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1. 发明申请

WO2013177058A1 TAGATOSE PRODUCTION USING SIMULATED MOVING BED SEPARATION 审中-公开
标题翻译：使用模拟移动床分离的标签生产
公开(公告)号：WO2013177058A1
公开(公告)日：2013-11-28
申请号：PCT/US2013/041853
申请日：2013-05-20
申请人： OROCHEM TECHNOLOGIES, INC.
发明人： OROSKAR, Anil, R. , KULKARNI, Omkar, M. , HOUSE, David, W. , SHARMA, Deepak , VIKRAMAN NAIR REMA, Rakesh
IPC分类号： C07H3/02 , C07H1/06 , B01D15/02 , B01D15/08
CPC分类号： C13K13/00 , B01D15/185 , B01D15/365 , B01J39/05 , B01J39/26 , B01J47/022 , C13K1/00
摘要： Disclosed is a process for the production of d-tagatose from lactose after acid hydrolysis to provide a hydrolysate having 1 equiv of d-glucose and 1 equiv of d-galactose for each unit of lactose converted. More particularly, the invention relates to a process for the isomerization of d-galactose to d-tagatose and the use of a simplified separation scheme based on simulated moving bed (SMB) separation. The isomerization of d-galactose to d-tagatose is carried out in the presence of calcium oxide or calcium hydroxide. The process is useful for providing a simplified processing route to providing pure d-tagatose and glucose as two products from lactose hydrolysate. In an alternate embodiment, a process is disclosed for the production of d-tagatose from fermented lactose hydrolysate to provide a crystallized d-tagatose product. D-tagatose is useful as a food additive, as a sweetener, as a texturizer, as a stabilizer, or as a humectant.
摘要翻译：公开了一种在酸水解之后从乳糖生产d-塔格糖的方法，以提供具有1当量的D-葡萄糖和1当量的D-半乳糖的水解产物，用于转化的每单位乳糖。更具体地，本发明涉及将D-半乳糖异构化为d-塔格糖的方法，以及使用基于模拟移动床（SMB）分离的简化分离方案。 D-半乳糖与D-塔格糖的异构化在氧化钙或氢氧化钙的存在下进行。该方法可用于提供简单的处理途径以从乳糖水解产物中提供纯的d-塔格糖和葡萄糖作为两种产物。在替代实施方案中，公开了用于从发酵乳糖水解产物生产d-塔格糖的方法，以提供结晶的d-塔格糖产品。 D-塔格糖可用作食品添加剂，甜味剂，增白剂，稳定剂，或作为保湿剂。

2. 发明申请

WO2013026159A1 TREATMENT OF WATER TO EXTEND HALF-LIFE OF OZONE 审中-公开
标题翻译：处理水以延长臭氧的使用寿命
公开(公告)号：WO2013026159A1
公开(公告)日：2013-02-28
申请号：PCT/CA2012/050572
申请日：2012-08-20
申请人： TERSANO INC. , HENGSPERGER, Steve, L. , NAMESPETRA, Justin, L. , O'NEIL, Jamie
发明人： HENGSPERGER, Steve, L. , NAMESPETRA, Justin, L. , O'NEIL, Jamie
IPC分类号： A61L2/20 , B01F3/04 , B01J47/00 , C01B13/10 , C02F1/78
CPC分类号： C02F9/00 , B01F3/04985 , B01F2003/04886 , B01J39/05 , B01J39/07 , B01J39/20 , B01J47/022 , B01J49/06 , B01J49/53 , C01B13/11 , C01B2201/22 , C01B2201/64 , C02F1/42 , C02F1/78 , C02F2001/425 , C02F2209/06
摘要： A system for providing an acidic ionized ozonated liquid. The system includes a liquid inlet arranged to accept a liquid into the system; an acid- based cation-exchange resin in fluid communication with the liquid inlet, the resin adapted to exchange cations in the accepted liquid with H+ ions on the resin; an ozone dissolving apparatus in fluid communication with the liquid inlet and the acid-based cation-exchange resin; and a liquid outlet in fluid communication with the liquid inlet, the acid-based cation-exchange resin and the ozone dissolving apparatus. The ozone dissolving apparatus and the acid-based cation-exchange resin cooperating to produce the acidic ionized ozonated liquid for dispensation out of the system via the liquid outlet.
摘要翻译：一种用于提供酸性离子化臭氧化液体的系统。该系统包括设置成将液体接纳到系统中的液体入口; 与液体入口流体连通的酸性阳离子交换树脂，树脂适于在树脂上与H +离子交换接受的液体中的阳离子; 与液体入口和酸性阳离子交换树脂流体连通的臭氧溶解装置; 以及与液体入口，酸性阳离子交换树脂和臭氧溶解装置流体连通的液体出口。臭氧溶解装置和酸性阳离子交换树脂协同生产酸性离子化臭氧化液体，用于通过液体出口排出系统。

3. 发明申请

WO2005123602A1 METHOD FOR MANUFACTURING CONTAINERS FOR THE TREATMENT OF LIQUIDS FOR FOOD USE 审中-公开
标题翻译：用于制造用于食物用液体处理的容器的方法
公开(公告)号：WO2005123602A1
公开(公告)日：2005-12-29
申请号：PCT/EP2005/005709
申请日：2005-05-24
申请人： AQUA S.P.A. , BONACINI, Claudio
发明人： BONACINI, Claudio
IPC分类号： C02F1/42
CPC分类号： B01J47/022 , B29C65/02 , B29C65/20 , B29C66/32 , B29C66/5432 , B29C66/8322 , B29L2031/14 , B29L2031/7154 , C02F1/42
摘要： The containers of the invention comprise a generally cylindrical intermediate tubular shell (2) and two opposing endpieces (3, 4) for its upper and lower closure. The manufacturing method of the invention comprises the following operative steps: separately preparing said shell (2) by obtaining it by cutting section from a commercial extruded tube of indeterminate length, separately preparing said two endpieces (3, 49 from a plastic material generally compatible with that of said shell (2), closely fitting said two endpieces (3, 4) to the opposing ends of said shell (2), and joining said endpieces (3, 4) and shell (2) together in a secure and sealed manner.
摘要翻译：本发明的容器包括一个大致圆柱形的中间管状壳体（2）和用于其上部和下部闭合件的两个相对的端部件（3,4）。本发明的制造方法包括以下操作步骤：通过从不确定长度的商业挤出管切割切割部分来分别制备所述外壳（2），分别制备所述两个末端（3,49，与塑料材料通常与所述壳体（2）的所述壳体（2）紧密地配合到所述壳体（2）的相对端部，并且将所述端部件（3,4）和壳体（2）以安全和密封的方式连接在一起。

4. 发明申请

WO2005000745A2 FLUID TREATMENT AND MEDIA MANAGEMENT DEVICE 审中-公开
标题翻译：流体处理和媒体管理设备
公开(公告)号：WO2005000745A2
公开(公告)日：2005-01-06
申请号：PCT/US2004/018654
申请日：2004-06-12
申请人： MARTIN, John, D.
发明人： MARTIN, John, D.
IPC分类号： C02F
CPC分类号： B01D46/30 , B01D15/00 , B01D15/206 , B01D24/08 , B01D24/4631 , B01D2265/06 , B01J47/022 , B01J49/00 , B01J49/75 , C02F1/281 , C02F2101/103
摘要： A fluid treatment and media management device having concentric inner and outer perforated cylinders defining a chamber therebetween for containing a media. A case surrounds the perforated cylinders and forms an annular space between the case and the outer perforated cylinder. Respective end caps engage the opposite ends of the case and perforated cylinders to support such members. One or both of the end caps provide ports to the central core of the inner perforated cylinder, to the media chamber and to the annular space. The media can be removed from the fluid treatment and media management device without disassembly of the device for the purpose of disposal and/or regeneration of the media.
摘要翻译：流体处理和介质管理装置（130）具有同心的内部（32）和外部（22）穿孔的圆柱体，在其间限定一个用于容纳介质的腔室（38）。壳体（16）围绕穿孔的圆柱体并且在壳体和外部穿孔圆筒之间形成环形空间（64）。相应的端盖（12,14）接合壳体的相对端和穿孔圆柱体以支撑这些构件。端盖中的一个或两个提供到内穿孔圆筒的中心芯部，介质室和环形空间的端口。介质可以从流体处理和介质管理装置中移除，而不用拆卸设备以便处理和/或再生介质。

5. 发明申请

WO2003059527A1 TOROIDAL VESSEL FOR UNIFORM, PLUG-FLOW FLUID DISTRIBUTION APPLICATIONS 审中-公开
标题翻译： TOROIDAL VESSEL FOR UNIFORM，PLUG-FLOW FLUID DISTRIBUTION APPLICATION
公开(公告)号：WO2003059527A1
公开(公告)日：2003-07-24
申请号：PCT/US2002/041308
申请日：2002-12-20
申请人： AMALGAMATED RESEARCH, INC.
发明人： COX, John, R.
IPC分类号： B05B17/08
CPC分类号： B01D53/0446 , B01D15/14 , B01J47/022 , B01J2219/1945 , G01N30/6017 , G01N30/6047 , Y10T137/2224 , Y10T137/85938 , Y10T137/86372
摘要： The present invention is an improved vessel body (1) for use in uniform plug-flow fluid applications, such as chromatography and adsorption bed processes. The improved vessel (1) is toroidal shaped and allows for a simpler distribution and collection system which is likewise claimed.
摘要翻译：本发明是一种改进的容器体（1），用于均匀的流动流体应用，例如色谱和吸附床方法。改进的容器（1）是环形的，并且允许同样要求保护的更简单的分配和收集系统。

6. 发明申请

WO01005502A1 DEVICE FOR THE SECONDARY PURIFICATION OF FERMENTATIVELY PRODUCED ORGANIC ACIDS 审中-公开
标题翻译： DEVICE FOR细洁发酵种植的有机ACIDS
公开(公告)号：WO01005502A1
公开(公告)日：2001-01-25
申请号：PCT/EP2000/006713
申请日：2000-07-13
IPC分类号： B01D15/04 , B01J47/02 , C07C51/47
CPC分类号： B01J47/022
摘要： The invention relates to a container in which a first horizontal nozzle grid is located. Said grid carries at least 1 m of an ion-exchanger bulk material. The container comprises a bottom section, a lid, at least one liquid inlet and at least one liquid outlet. The individual nozzles of the grid are detachably linked with the nozzle grid by screw connections.
摘要翻译：该装置包括在该第一水平喷嘴格栅布置在容器中。网格携带离子交换材料的床的至少1m <3>。该容器具有一个底部，一个盖，至少一个液体入口和至少一个液体出口。炉篦的各个喷嘴可释放地通过螺纹连接于喷嘴格栅连接。

7. 发明申请

WO1996007462A1 SIEVE SYSTEM FOR AN ION EXCHANGE COLUMN 审中-公开
标题翻译：离子交换柱SIEVE系统
公开(公告)号：WO1996007462A1
公开(公告)日：1996-03-14
申请号：PCT/US1995010729
申请日：1995-08-29
申请人： HENKEL CORPORATION
发明人： HENKEL CORPORATION , HART, Robert, G. , AHMED, Bashir, M. , GONZALES, Carlos , KOZAK, William, G.
IPC分类号： B01D24/38
CPC分类号： C02F1/42 , B01D29/15 , B01J47/022
摘要： Apparatus for use in an ion exchange unit or column comprising a riser pipe, a port (16) coupled to one end of said pipe, a first rigid cylinder (64) having apertures therein mounted concentrically on the pipe, a port coupled to the space between the pipe and said cylinder (64), a mesh sleeve (74) concentrically mounted about the cylinder (64), a sieve (84) mounted about the mesh sleeve (74), a second rigid cylinder (94) concentric with the pipe and near its outer end, a second mesh sleeve (104) mounted about said second rigid cylinder (94), and a sieve bag (114) containing the second mesh sleeve (104). The aperture size in said sieve material is only sufficiently fine to prevent the passage of ion exchange resin beads.
摘要翻译：用于离子交换单元或柱的装置，其包括提升管，连接到所述管的一端的端口（16），具有其中同心地安装在管上的孔的第一刚性圆筒（64），连接到所述空间的端口在所述管和所述圆筒（64）之间，围绕所述圆筒（64）同心安装的网孔套筒（74），围绕所述网孔套筒（74）安装的筛子（84），与所述管道同心的第二刚性圆柱体并且在其外端附近，围绕所述第二刚性圆筒（94）安装的第二网眼套筒（104）和包含所述第二网状套筒（104）的筛袋（114）。所述筛材料中的孔径尺寸仅足够小以防止离子交换树脂珠粒通过。

8. 发明申请

WO1995011754A1 DEMINERALIZATION CARTRIDGE 审中-公开
标题翻译：分解盒
公开(公告)号：WO1995011754A1
公开(公告)日：1995-05-04
申请号：PCT/FR1994001201
申请日：1994-10-17
申请人： MOULINEX S.A. , FOURNY, Jacky, René, Paul , GUILLOT, Gérard, Louis, Henri
发明人： MOULINEX S.A.
IPC分类号： B01J47/02
CPC分类号： D06F75/14 , B01J47/022 , B01J47/024 , B01J49/90
摘要： Removable demineralization cartridge (1) for insertion in the water system of an appliance. Said cartridge comprises a chamber (8) located between a liquid inlet (5) and outlet (6), and containing a powder demineralization resin (7). According to the invention, the chamber (8) contains means (10) for offseting the variations in the volume of the resin (7). Said means are capable of either expanding to offset a reduction in the volume of the resin, or contracting to absorb an increase in the volume of said resin. The removable cartridge is useful for demineralizing water used in irons.
摘要翻译：用于插入设备的水系统中的可移除的软化软管（1）。所述筒包括位于液体入口（5）和出口（6）之间并包含粉末脱矿质树脂（7）的腔室（8）。根据本发明，室（8）包含用于抵消树脂（7）的体积变化的装置（10）。所述装置能够膨胀以抵消树脂体积的减小，或收缩以吸收所述树脂体积的增加。可拆卸的墨盒可用于熨斗熨斗中使用的水。

9. 发明申请

WO1991008814A1 FLUID TREATMENT DEVICES 审中-公开
标题翻译：流体处理装置
公开(公告)号：WO1991008814A1
公开(公告)日：1991-06-27
申请号：PCT/US1990007298
申请日：1990-12-17
申请人： EASTMAN KODAK COMPANY
发明人： EASTMAN KODAK COMPANY , EDWARDS, Evan, Albert , HARISSIS, Peter, John , MENON, Krishna, Sankarankutty
IPC分类号： B01D15/00
CPC分类号： B01J47/022 , C02F1/283 , C02F1/42 , C02F2201/006
摘要： A fluid treatment device (10) is described which includes a cylindrical housing (12) with fluid inlet and outlet means (18, 40) at or adjacent opposite ends (16, 18). Particulate material (62) for treating fluid flowed through the device (10), is disposed within the housing, between the inlet and outlet means (18, 40). A helical baffle (60) is disposed within the housing (12) in the particulate material (62). The baffle (60) extends axially along the housing (12) and the free edges of its fins (68, 72, 80) are in contact with the housing (12). The baffle (60) serves to impose a helical path on fluid flowing through the device so that, when the device is mounted with its axis (64) horizontal and with a volume of particulate material (62) less than the volume of the space within the housing (12), fluid flows through the particulate material (62) most of the time and not entirely along the void as would be the case if the baffle were not present.

10. 发明申请

WO2017100674A1 SCALABLE PURIFICATION METHOD FOR AAV1 审中-公开
标题翻译：可扩展的AAV1净化方法
公开(公告)号：WO2017100674A1
公开(公告)日：2017-06-15
申请号：PCT/US2016/065974
申请日：2016-12-09
申请人： THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
发明人： LOCK, Martin , ALVIRA, Mauricio
IPC分类号： B01D15/08 , B01J20/281 , C12N7/00
CPC分类号： B01D15/08 , B01D15/166 , B01D15/363 , B01D15/3804 , B01J41/05 , B01J41/13 , B01J41/20 , B01J47/022 , C12N7/00
摘要： A two-step chromatography purification scheme is described which selectively captures and isolates the genome-containing rAAV vector particles from the clarified, concentrated supematant of a rAAV production cell culture. The process utilizes an affinity capture method performed at a high salt concentration followed by an anion exchange resin method performed at high pH to provide rAAV vector particles which are substantially free of rAAV intermediates.
摘要翻译：描述了两步色谱纯化方案，其从rAAV生产细胞培养物的澄清浓缩上清液中选择性捕获和分离含基因组的rAAV载体颗粒。该方法利用在高盐浓度下进行的亲和捕获方法，接着在高pH下进行阴离子交换树脂方法，以提供基本上不含rAAV中间体的rAAV载体颗粒。

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