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1. 发明申请

WO2013052261A3 HARMONIC COLD PLASMA DEVICES AND ASSOCIATED METHODS 审中-公开
标题翻译：谐波冷等离子体装置和相关方法
公开(公告)号：WO2013052261A3
公开(公告)日：2013-06-27
申请号：PCT/US2012055571
申请日：2012-09-14
申请人： COLD PLASMA MEDICAL TECHNOLOGIES INC , WATSON GREGORY A , HUMMEL ROBERT M , JACOFSKY MARC C , JACOFSKY DAVID J
发明人： WATSON GREGORY A , HUMMEL ROBERT M , JACOFSKY MARC C , JACOFSKY DAVID J
IPC分类号： H01J7/24
CPC分类号： H05H1/46 , A61L2/00 , A61L2/0011 , A61L2/0094 , A61L2/14 , A61L2202/11 , A61M15/02 , A61M16/06 , A61M16/12 , A61M2202/0208 , A61M2202/025 , A61N1/40 , A61N1/44 , H01J37/321 , H01J37/32348 , H01J37/3244 , H01J37/3266 , H05H1/2406 , H05H2001/2412 , H05H2001/466 , H05H2001/4682 , H05H2240/20 , H05H2245/1225 , H05H2277/10
摘要： A gas cartridge is described that is configured to provide sufficient gas to support cold plasma generation for a specific medical process. The gas cartridge has a seal that is pierced upon connection of the gas cartridge to the cold plasma delivery system. Different embodiments are described that use different connection locations between the gas cartridge and the cold plasma delivery system. A shroud is also described that shields the user if the cold plasma delivery system is dropped and the gas cartridge ruptures. Use of an ID system assists in ensuring that the correct gas mixture, correct gas cartridge and correct power supply settings are used for the particular medical treatment process.
摘要翻译：描述了配置成提供足够的气体以支持特定医疗过程的冷等离子体产生的储气瓶。储气筒具有密封件，在将储气筒连接到冷等离子体输送系统时，密封件被刺穿。描述了使用储气瓶与冷等离子体输送系统之间的不同连接位置的不同实施例。还描述了一种护罩，如果冷等离子体输送系统掉落并且储气筒破裂，则该护罩可以保护使用者。使用ID系统有助于确保在特定的医疗处理过程中使用正确的气体混合物，正确的气体墨盒和正确的电源设置。

2. 发明申请

WO2013052261A2 HARMONIC COLD PLASMA DEVICES AND ASSOCIATED METHODS 审中-公开
标题翻译：谐波冷等离子体装置及相关方法
公开(公告)号：WO2013052261A2
公开(公告)日：2013-04-11
申请号：PCT/US2012/055571
申请日：2012-09-14
申请人： COLD PLASMA MEDICAL TECHNOLOGIES, INC. , WATSON, Gregory, A. , HUMMEL, Robert, M. , JACOFSKY, Marc, C. , JACOFSKY, David, J.
发明人： WATSON, Gregory, A. , HUMMEL, Robert, M. , JACOFSKY, Marc, C. , JACOFSKY, David, J.
IPC分类号： A61M37/00
CPC分类号： H05H1/46 , A61L2/00 , A61L2/0011 , A61L2/0094 , A61L2/14 , A61L2202/11 , A61M15/02 , A61M16/06 , A61M16/12 , A61M2202/0208 , A61M2202/025 , A61N1/40 , A61N1/44 , H01J37/321 , H01J37/32348 , H01J37/3244 , H01J37/3266 , H05H1/2406 , H05H2001/2412 , H05H2001/466 , H05H2001/4682 , H05H2240/20 , H05H2245/1225 , H05H2277/10
摘要： A gas cartridge is described that is configured to provide sufficient gas to support cold plasma generation for a specific medical process. The gas cartridge has a seal that is pierced upon connection of the gas cartridge to the cold plasma delivery system. Different embodiments are described that use different connection locations between the gas cartridge and the cold plasma delivery system. A shroud is also described that shields the user if the cold plasma delivery system is dropped and the gas cartridge ruptures. Use of an ID system assists in ensuring that the correct gas mixture, correct gas cartridge and correct power supply settings are used for the particular medical treatment process.
摘要翻译：描述了一种气体盒，其构造成提供足够的气体以支持用于特定医疗过程的冷等离子体产生。燃气筒具有密封件，该密封件在气瓶连接到冷等离子体输送系统时被刺穿。描述了使用气瓶和冷等离子体输送系统之间的不同连接位置的不同实施例。还描述了如果冷等离子体输送系统掉落并且气瓶破裂，则屏蔽用户。使用ID系统有助于确保在特定医疗过程中使用正确的气体混合物，正确的气瓶和正确的电源设置。

3. 发明申请

WO2013040486A1 COLD PLASMA TREATMENT DEVICES AND ASSOCIATED METHODS 审中-公开
标题翻译：冷等离子体处理装置及相关方法
公开(公告)号：WO2013040486A1
公开(公告)日：2013-03-21
申请号：PCT/US2012/055615
申请日：2012-09-14
申请人： COLD PLASMA MEDICAL TECHNOLOGIES, INC. , WATSON, Gregory, A. , JACOFSKY, Marc, C.
发明人： WATSON, Gregory, A. , JACOFSKY, Marc, C.
IPC分类号： H01J7/24
CPC分类号： H05H1/46 , A61L2/00 , A61L2/0011 , A61L2/0094 , A61L2/14 , A61L2202/11 , A61M15/02 , A61M16/06 , A61M16/12 , A61M2202/0208 , A61M2202/025 , A61N1/40 , A61N1/44 , H01J37/321 , H01J37/32348 , H01J37/3244 , H01J37/3266 , H05H1/2406 , H05H2001/2412 , H05H2001/466 , H05H2001/4682 , H05H2240/20 , H05H2245/1225 , H05H2277/10
摘要： An inhalable cold plasma mask device for generation of a breathable cold plasma for delivery to a patient. A biocompatible gas is received in a dielectric barrier discharge (DBD) device that is energized by an electrode that receives energy from a pulsed source. The DBD device can be grounded by a grounding structure. A grounding screen can be used prior to inhalation of the cold plasma. The inhalable cold plasma mask device includes the use of a single-layer or a two-layer approach to its construction. The inhalable cold plasma mask device can have one or two DBD devices. Such a device and associated method can be used to treat upper respiratory tract infections, as well as reducing inflammation, sinus and esophageal polyps in both size and frequency of occurrence.
摘要翻译：一种可吸入的冷等离子体掩模装置，用于产生用于输送给患者的透气冷等离子体。在由从脉冲源接收能量的电极激励的介电阻挡放电（DBD）器件中接收生物相容性气体。 DBD设备可以通过接地结构接地。在吸入冷等离子体之前可以使用接地屏。可吸入的冷等离子体掩模装置包括使用单层或双层方法构造。可吸入的冷等离子体掩模装置可以具有一个或两个DBD装置。这种装置和相关方法可用于治疗上呼吸道感染，以及减少发生的大小和频率的炎症，窦和食道息肉。

4. 发明申请

WO2011100165A1 APPARATUS AND METHOD FOR TREATING STORED CROPS INFECTED WITH TOXINS 审中-公开
标题翻译：用于治疗用毒素感染的储存的作物的装置和方法
公开(公告)号：WO2011100165A1
公开(公告)日：2011-08-18
申请号：PCT/US2011/023751
申请日：2011-02-04
申请人： PURELINE TREATMENT SYSTEMS, LLC , O'CONNELL, Thomas W.
发明人： O'CONNELL, Thomas W.
IPC分类号： A23B9/18 , A23B9/30 , A23L3/3409 , A23L3/358
CPC分类号： A61L2/0094 , A23B9/18 , C01B11/024 , C01B11/026
摘要： A method of reducing toxins in stored crops comprises producing a stream of aqueous or gas ClO 2 and exposing the stored crops to the ClO 2 wherein the ClO 2 kills toxin- producing microorganisms and/or reacts with toxins to reduce the toxins in said stored crops. An apparatus for reducing toxins in stored crops comprises a treatment area for containing the stored crops and a ClO 2 generator comprising an inlet for introducing at least one chlorine-containing feed chemical and an outlet for exhausting a stream of aqueous or gas ClO 2 from the generator into the treatment area wherein introducing the ClO 2 kills toxin- producing microorganisms and/or reacts with toxin molecules to reduce the toxins in the stored crops.
摘要翻译：减少储存作物中的毒素的方法包括产生水或气体ClO 2流，并将储存的作物暴露于ClO 2，其中ClO 2杀死产生毒素的微生物和/或与毒素反应以减少所述存储的作物中的毒素。用于减少储存的作物中的毒素的装置包括用于容纳储存的作物的处理区域和包含用于引入至少一个含氯进料化学品和用于将来自发生器的水或气体ClO气流排出的出口的入口的ClO 2发生器其中引入ClO 2的处理区域杀死产生毒素的微生物和/或与毒素分子反应以减少存储的作物中的毒素。

5. 发明申请

WO2009079309A3 ULTRAVIOLET LIGHT TREATMENT CHAMBER 审中-公开
标题翻译： ULTRAVIOLET光源处理室
公开(公告)号：WO2009079309A3
公开(公告)日：2009-09-11
申请号：PCT/US2008086305
申请日：2008-12-11
申请人： ULTRAVIOLET SCIENCES INC , COOPER JAMES RANDALL , MAY RICHARD
发明人： COOPER JAMES RANDALL , MAY RICHARD
IPC分类号： C02F1/32 , A61L2/10 , A61L9/20 , G01N21/00
CPC分类号： B01J19/123 , A61L2/0011 , A61L2/0094 , A61L9/015 , A61L9/205 , A61L2209/212 , A61M1/3681 , A61M1/3683 , A61M2205/053 , B01J19/124 , B01J2219/0877 , C02F1/283 , C02F1/325 , C02F1/42 , C02F1/441 , C02F2201/003 , C02F2201/3223 , C02F2201/3228 , C02F2201/328
摘要： An apparatus for the treatment of a liquid comprising includes a chamber having at least one inner surface. The chamber is at least 80 percent enclosed. The apparatus also includes an ultraviolet (UV) transmissive tube and the UV transmissive tube disposed within the chamber and adapted for the passage of the liquid therethrough. The apparatus further includes an UV lamp and the UV lamp being disposed within the UV transmissive tube. A reflective material is interspersed between the chamber and the transmissive tube, and the reflective material is adapted so as to reflect at least a portion of light emitted by the UV lamp. Additionally, the reflective material is at least 80 percent reflective.
摘要翻译：一种用于处理液体的设备包括具有至少一个内表面的腔室。该室至少80％封闭。该设备还包括紫外（UV）透射管和设置在腔室内并适于使液体通过其中的UV透射管。该设备还包括UV灯，并且UV灯设置在UV透射管内。反射材料散布在腔室和透射管之间，并且反射材料适于反射由UV灯发射的至少一部分光。另外，反射材料至少80％是反射性的。

6. 发明申请

WO2008154628A3 PROCESS FOR STERILIZING ACELLULAR SOFT TISSUE UNDER VACUUM 审中-公开
标题翻译：在真空下灭菌细胞软组织的方法
公开(公告)号：WO2008154628A3
公开(公告)日：2009-02-12
申请号：PCT/US2008066697
申请日：2008-06-12
申请人： MUSCULOSKELETAL TRANSPLANT , NGO MANH-DAN , CARTMELL JEFFREY STUART , GERTZMAN ARTHUR A
发明人： NGO MANH-DAN , CARTMELL JEFFREY STUART , GERTZMAN ARTHUR A
IPC分类号： A61L27/36 , A61L2/14 , A61L2/20 , A61L27/60
CPC分类号： A61L27/60 , A61L2/0082 , A61L2/0094 , A61L27/362 , A61L27/3687 , A61L27/3691
摘要： The present invention is a process for preparing skin removed from a human donor, removal of cellular components and sterilizing the decellularized skin. The process comprises the following steps: (a) decellularizing the skin including soaking the skin in a detergent and rinsing same with sterile water; (b) sterilizing the skin under vacuum with one or more of ozone, vapor H2O2, plasma H 2O2, ethylene oxide gas, or sodium hydroxide for a time period to achieve a concentration to achieve sterilization of the skin; and (c) processing the skin by cutting the skin to a designated size.
摘要翻译：本发明是用于制备从人供体移除的皮肤的方法，去除细胞组分并对脱细胞的皮肤进行灭菌。该方法包括以下步骤：（a）使皮肤脱细胞化，包括将皮肤浸泡在洗涤剂中并用无菌水冲洗; （b）用真空中的一种或多种臭氧，蒸汽H 2 O 2，血浆H 2 O 2，环氧乙烷气体或氢氧化钠对皮肤进行灭菌一段时间以达到浓缩以实现皮肤的灭菌; 和（c）通过将皮肤切割成指定尺寸来处理皮肤。

7. 发明申请

WO2008077155A1 STERILIZATION OF OBJECTS CONTAINING BIOLOGICAL MOLECULES 审中-公开
标题翻译：包含生物分子的物体的灭菌
公开(公告)号：WO2008077155A1
公开(公告)日：2008-06-26
申请号：PCT/US2007/088728
申请日：2007-12-21
申请人： GENENTECH, INC. , LAM, Xanthe, M. , NGUYEN, Tue
发明人： LAM, Xanthe, M. , NGUYEN, Tue
IPC分类号： A61L2/00 , A61L2/20
CPC分类号： A61L2/206 , A61L2/0094
摘要： The invention relates to methods for surface-sterilizing objects containing ethylene-oxide-sensitive, temperature-sensitive compounds, including biological molecules.
摘要翻译：本发明涉及用于表面消毒含有环氧乙烷敏感的温度敏感化合物（包括生物分子）的物体的方法。

8. 发明申请

WO2008046211A1 METHODS AND DEVICES FOR THE DELIVERY OF THERAPEUTIC GASES INCLUDING NITRIC OXIDE 审中-公开
标题翻译：用于输送包括氮氧化物的治疗气体的方法和装置
公开(公告)号：WO2008046211A1
公开(公告)日：2008-04-24
申请号：PCT/CA2007/001838
申请日：2007-10-19
申请人： PULMONOX TECHNOLOGIES CORPORATION , HOLE, Douglas, R. , FIGLEY, Curtis , LEE, Robert, E. , HUDEC, Michael , ROLFSON, Robert
发明人： HOLE, Douglas, R. , FIGLEY, Curtis , LEE, Robert, E. , HUDEC, Michael , ROLFSON, Robert
IPC分类号： A61L2/20 , A61F13/00 , A61J1/05 , A61L15/44 , A61M16/10 , A61M31/00 , A61M37/00 , A61K9/70 , A61K33/00
CPC分类号： A61K33/00 , A61F13/0216 , A61F13/0226 , A61F13/8405 , A61F2013/00646 , A61F2013/0091 , A61J3/08 , A61K9/7007 , A61L2/0094 , A61L15/44 , A61L2300/114 , A61L2300/60 , A61M16/1055 , A61M16/106 , A61M16/12 , A61M16/208 , A61M2202/0275
摘要： Gas packages for the delivery of therapeutic gases, and in particular gaseous nitric oxide (gNO) are provided herein. The gas packages comprise one or more of a gas reservoir, interface layer, sealing layer, and holding container. The interface layer regulates discharge of the therapeutic gas from the gas reservoir to the external environment. The sealing layer and/or holding container prevent evolution of the gas until the sealing layer is compromised or the holding container is opened. The gas packages and methods for using them are useful for the treatment, alleviation, and prevention of various disease and non-disease, medical and non-medical, conditions in humans and animals.
摘要翻译：用于递送治疗气体的气体包装，特别是气态一氧化氮（gNO）。气体包装包括气体储存器，界面层，密封层和保持容器中的一个或多个。界面层调节治疗气体从气体储存器到外部环境的排放。密封层和/或保持容器防止气体逸出，直到密封层受损或保持容器打开。气体包装和使用它们的方法可用于治疗，缓解和预防人类和动物中的各种疾病和非疾病，医学和非医学的条件。

9. 发明申请

WO2007106888A3 OZONE BASED SANITIZER 审中-公开
标题翻译：基于臭氧的消毒剂
公开(公告)号：WO2007106888A3
公开(公告)日：2007-12-13
申请号：PCT/US2007064070
申请日：2007-03-15
申请人： GERMGARD LIGHTING LLC , GORDON EUGENE I
发明人： GORDON EUGENE I
IPC分类号： A61L2/20 , A61L2/18 , A61L9/00
CPC分类号： A61L2/0094 , A61L2/202
摘要： A sanitizing apparatus having an enclosure (110), and inlet connector (120) and an exhaust-outlet (140) is provided. The enclosure (110) of the apparatus is substantially impermeable to ozone and has an inner volume and a sealable opening (160). Inanimate items or user's bodily extremities can be inserted into the opening (160) which can be sealed to form an airtight barrier around or with the inserted item. Ozone can be introduced to the inner volume through the inlet-connector (120). Pathogens on the surface of the item are deactivated through the exposure to ozone. Clumped pathogens can be broken down using vibrational energy or rubbing. Once sanitized, the oxygen-based gas mixture contained in the enclosure can be released through the exhaust-outlet (140). Catalysts, such as carbon filters and heat, can be used to ensure that all ozone has been decomposed into oxygen. The sanitizing apparatus is safe, rapid, and effective.
摘要翻译：提供具有外壳（110）和入口连接器（120）和排气口（140）的消毒设备。设备的外壳（110）基本上不可渗透臭氧并具有内容积和可密封的开口（160）。无生命物品或用户的肢体可以插入到开口（160）中，该开口可以被密封以在插入的物品周围或与插入的物品形成气密的屏障。臭氧可以通过入口连接器（120）引入内部容积。物品表面的病原体通过暴露于臭氧而被去活化。聚集的病原体可以使用振动能量或摩擦来分解。一旦消毒，包含在外壳中的氧基气体混合物可以通过排气口（140）释放。可以使用诸如碳过滤器和热量的催化剂来确保所有臭氧已经分解成氧气。消毒设备安全，快速，有效。

10. 发明申请

WO2007070301A9 VASCULAR GRAFT STERILIZATION AND DECELLULARIZATION 审中-公开
标题翻译：血管移植杀菌和去细胞化
公开(公告)号：WO2007070301A9
公开(公告)日：2007-09-20
申请号：PCT/US2006046514
申请日：2006-12-05
申请人： REGENERATION TECH INC , SQUILLACE DONNA , ALEXANDER ANTHONY
发明人： SQUILLACE DONNA , ALEXANDER ANTHONY
IPC分类号： A61K35/14 , A61F2/02
CPC分类号： A61L2/0088 , A61L2/0094 , A61L27/3687 , A61L27/507 , A61L2430/40
摘要： The present technology is related to the field of sterilization and decellularization of allografts or xenografts, specifically to processes that achieve effective removal of the cells contained within a vascular tissue matrix and an effective reduction in potential harmful organisms to create grafts suitable for human implantation. In some embodiments, vascular grafts, vascular tissue and/or blood vessels are contacted with cleaning solution under conditions suitable conditions to reduce immune reaction in patients. More specifically, the present technology is directed to sterilization and decellularization of vascular grafts.
摘要翻译：本技术涉及同种异体移植物或异种移植物的灭菌和去细胞化领域，具体涉及实现有效去除血管组织基质内包含的细胞并有效减少潜在有害生物体以产生适合人类移植的移植物的过程。在一些实施例中，血管移植物，血管组织和/或血管在适合条件的条件下与清洁溶液接触以减少患者的免疫反应。更具体地说，本技术涉及血管移植物的灭菌和脱细胞。

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