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1. 发明申请

WO2014015295A1 TRANSDUCER INTERFACE SYSTEM AND METHOD 审中-公开
标题翻译：传感器接口系统和方法
公开(公告)号：WO2014015295A1
公开(公告)日：2014-01-23
申请号：PCT/US2013/051365
申请日：2013-07-19
申请人： BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
发明人： PURDY, Phillip Douglas , JENNINGS, Ronald Bruce
IPC分类号： A61B5/02
CPC分类号： A61B5/02154 , A61B5/02156 , A61B5/02158 , A61B5/024 , A61B5/031 , A61B5/032 , A61B5/6853 , A61B5/72 , A61B5/7225 , A61B5/742 , G01L9/00 , G01L19/12 , G01L27/007
摘要： A transducer interface system/method allowing conversion from an analog sensor input to a standardized analog output interface is disclosed. In some preferred embodiments the system/method permits a fiber optic pressure sensor to be interfaced to a standard patient care monitor (PCM) system using standardized Wheatstone Bridge analog interface inputs. Within this context the Wheatstone Bridge sensed output is defined by stimulus from the PCM and modulation of bridge element values by the conditioned output of an analog pressure sensor. The use of analog-to-digital-to-analog conversion in this transducer interface permits retrofitting of PCM devices having analog Wheatstone Bridge inputs with advanced patient monitoring sensors without the need for specialized modifications to the baseline PCM data collection framework. Methods disclosed herein include techniques to connect arbitrary types/numbers of analog sensors to traditional PCM systems without the need for PCM system hardware/software modifications.
摘要翻译：公开了一种允许从模拟传感器输入到标准化模拟输出接口的转换的传感器接口系统/方法。在一些优选实施例中，系统/方法允许使用标准化的惠斯通电桥模拟接口输入将光纤压力传感器接口到标准的病人护理监视器（PCM）系统。在这种情况下，惠斯通电桥感测输出由PCM的激励定义，并通过模拟压力传感器的调节输出调制桥元件值。在该传感器接口中使用模数转换器可以对具有模拟惠斯顿电桥输入的PCM器件进行改造，并且不需要对基线PCM数据采集框架进行专门的修改。本文公开的方法包括将任意类型/数量的模拟传感器连接到传统PCM系统而不需要PCM系统硬件/软件修改的技术。

2. 发明申请

WO2011018706A1 IN SITU OFFSET COMPENSATION FOR PRESSURE SENSORS 审中-公开
标题翻译：用于压力传感器的现场偏移补偿
公开(公告)号：WO2011018706A1
公开(公告)日：2011-02-17
申请号：PCT/IB2010/002178
申请日：2010-08-12
申请人： BURGER, Juergen , BORK, Toralf
发明人： BURGER, Juergen , BORK, Toralf
IPC分类号： A61B5/00 , A61B5/03 , G01L9/00 , G01L27/00
CPC分类号： A61B5/6846 , A61B5/0031 , A61B5/031 , A61B5/032 , A61B2560/0223 , A61B2562/0247 , G01L19/02 , G01L27/002
摘要： A pressure sensor having a substrate and a first, deformable membrane, partially supported by the substrate, which generates a first sensor reading when deformed by pressure. A second membrane is contiguous to the first membrane. When the second membrane is energized, it deforms the first membrane to alter the first sensor reading. The objective of the invention is to enable automatic correction of sensor readings without input from a user.
摘要翻译：一种压力传感器，其具有基板和由基板部分支撑的第一可变形膜，当通过压力变形时产生第一传感器读数。第二个膜与第一个膜相邻。当第二个膜通电时，它会使第一个膜变形，从而改变第一个传感器读数。本发明的目的是使得能够在没有用户输入的情况下自动校正传感器读数。

3. 发明申请

WO2010112555A1 OPTIMIZATION OF HYDROCEPHALUS SHUNT SETTINGS 审中-公开
标题翻译： HYDROCEPHALUS SHUNT设置优化
公开(公告)号：WO2010112555A1
公开(公告)日：2010-10-07
申请号：PCT/EP2010/054334
申请日：2010-03-31
申请人： LIKVOR AB , SUNDSTRÖM, Nina , EKLUND, Anders , MALM, Jan
发明人： SUNDSTRÖM, Nina , EKLUND, Anders , MALM, Jan
IPC分类号： A61M27/00 , A61B5/03
CPC分类号： A61M27/006 , A61B5/031 , A61B5/032
摘要： A method is described for using a postoperative CSF dynamical examination to determine the CSF dynamical state of the patient and the dynamical state of the CSF shunt in conjunction therewith.
摘要翻译：描述了一种使用术后CSF动力学检查来确定患者的CSF动态状态和与其结合的CSF分流的动态状态的方法。

4. 发明申请

WO2010108337A1 硬膜外腔穿刺装置审中-公开
公开(公告)号：WO2010108337A1
公开(公告)日：2010-09-30
申请号：PCT/CN2009/071562
申请日：2009-04-29
申请人：孙东
发明人：孙东
IPC分类号： A61B17/34 , A61B5/03
CPC分类号： A61B5/032 , A61B17/3401 , A61B17/3403 , A61B2090/064 , A61B2090/0807

5. 发明申请

WO2007146616A2 DEVICES AND METHODS FOR DETECTION OF MARKERS OF AXIAL PAIN WITH OR WITHOUT RADICULOPATHY 审中-公开
标题翻译：用于检测具有或不具有RADICULOPATHY的轴向疼痛标记物的装置和方法
公开(公告)号：WO2007146616A2
公开(公告)日：2007-12-21
申请号：PCT/US2007/070174
申请日：2007-06-01
申请人： WARSAW ORTHOPEDIC, INC , MCKAY, William F. , GROSS, Jeffrey M. , TRIEU, Hai H. , ROY, Josee , DRAPEAU, Susan J. , SCHENDEL, Michael J. , WALSH, Andrew J.l.
发明人： MCKAY, William F. , GROSS, Jeffrey M. , TRIEU, Hai H. , ROY, Josee , DRAPEAU, Susan J. , SCHENDEL, Michael J. , WALSH, Andrew J.l.
CPC分类号： A61B5/14546 , A61B5/0031 , A61B5/0071 , A61B5/0084 , A61B5/01 , A61B5/032 , A61B5/14539 , A61B5/4514 , A61B5/4561 , A61B5/4824 , A61B5/4896 , A61B5/6848 , G01N33/54366 , G01N33/6896 , G01N2800/2842
摘要： The invention provides devices and related methods and composition useful for diagnosis and monitoring the pain generator(s) of axial pain with or without radiculopathy and methods for screening test compounds potentially useful for treating axial pain with or without radiculopathy. Alternatively, degenerated discs can be monitored and treated before occurrence of a pathological pain condition. Pain markers and markers of degenerating disc include markers of neuronal, vascular, immune and matrix elements.
摘要翻译：本发明提供了用于诊断和监测具有或不具有神经根病变的轴向疼痛的疼痛发生器的装置和相关方法和组合，以及用于筛选潜在地可用于治疗或不发生神经根病变的轴向疼痛的测试化合物的方法。或者，可以在发生病理性疼痛状况之前监测和治疗退化的椎间盘。退行性椎间盘的疼痛标志物和标志物包括神经元，血管，免疫和基质元件的标记物。

6. 发明申请

WO2004095179A2 INTEGRATED POINT-OF-CARE SYSTEMS AND METHODS 审中-公开
标题翻译：综合点保护系统和方法
公开(公告)号：WO2004095179A2
公开(公告)日：2004-11-04
申请号：PCT/US2004/011789
申请日：2004-04-16
申请人： MEDICAL INTERACTIVE CORPORATION , SMITH, Baird
发明人： SMITH, Baird
IPC分类号： G06F
CPC分类号： G06Q50/24 , A61B5/0013 , A61B5/02055 , A61B5/021 , A61B5/02152 , A61B5/032 , A61B5/0402 , A61B5/0833 , A61B5/0836 , A61B5/145 , A61B5/14532 , A61B5/411 , A61B2560/0437 , A61G7/05 , A61M2205/505 , G06F19/00 , G06F19/321 , G06F19/3418 , G06F19/3456 , G06Q50/22 , G16H10/60 , G16H40/63
摘要： An integrated point-of-care system includes a medical monitoring device, a medical care device, a computing system, and a structure. The medical monitoring device monitors patient information for a patient. The medical care device provides medical care to the patient. The computing system receives patient information from the medical monitoring device and transmits control instructions to the medical care device to control the medical care to the patient. The computing system also exchanges data with a central data respository through a communication network. The structure supports the patient, the medical monitoring device, the medical care device, and the computing system. The structure can also transport the patient, the medical monitoring device, the medical care device, and the computing system together.

7. 发明申请

WO2019012097A1 BIOMARKERS FOR VISUAL IMPAIRMENT AND INTRACRANIAL PRESSURE (VIIP) SYNDROME 审中-公开
公开(公告)号：WO2019012097A1
公开(公告)日：2019-01-17
申请号：PCT/EP2018/069061
申请日：2018-07-13
申请人： P&X MEDICAL NV
发明人： WOSTYN, Peter
IPC分类号： A61B3/12 , A61B5/03 , A61B5/00
CPC分类号： A61B5/032 , A61B3/12 , A61B5/031 , A61B5/1072 , A61B5/7275 , A61B2503/20 , A61M5/142 , A61M5/158 , A61M5/1723 , A61M2202/0464 , A61M2205/3331 , A61M2205/3344 , G16H20/13 , G16H50/30
摘要： The optic nerve sheath (ONS) response to alterations in cerebrospinal fluid (CSF) pressure induced by infusion of artificial cerebrospinal fluid is used as a biomarker for predicting the risk of developing Visual Impairment and Intracranial Pressure(VIIP) syndrome in a subject.

8. 发明申请

WO2015157320A1 IMPLANTABLE SELF-CALIBRATING SENSOR ASSEMBLIES AND ASSOCIATED METHODS 审中-公开
标题翻译：可植入的自我校准传感器总成及相关方法
公开(公告)号：WO2015157320A1
公开(公告)日：2015-10-15
申请号：PCT/US2015/024762
申请日：2015-04-07
申请人： BROWD, Samuel, R. , LUTZ, Barry , CLEMENT, Thomas, J. , RELETHFORD, Joel , SALSTROM, Jared
发明人： BROWD, Samuel, R. , LUTZ, Barry , CLEMENT, Thomas, J. , RELETHFORD, Joel , SALSTROM, Jared
IPC分类号： A61B5/03 , G01L7/02
CPC分类号： A61B5/032 , A61B5/031 , A61B5/6847 , A61B2560/0223 , A61B2562/0247 , A61M27/006 , A61M2205/3331 , A61M2230/005 , G01L9/0001 , G01L19/0023 , G01L27/002
摘要： Self-calibrating sensor assemblies for excess body fluid drainage systems are disclosed herein. Self-calibrating sensor assemblies can include a sensor assembly engaged with a flexible interface member of a drainage catheter. The assembly includes a sensor having a body and a shaft extending from the body. A contact member is slidably mated with the shaft and coupled to the flexible interface member. A resilient member is coupled to the sensor shaft and disposed between the contact member and the body. An actuator moves the sensor between a first position and a second position with respect to the drainage catheter. In the first position the sensor is positioned to measure the pressure and/or force at the flexible interface member, and in the second position the resilient member exerts a known force on the sensor.
摘要翻译：本文公开了用于多余体液排出系统的自校准传感器组件。自校准传感器组件可以包括与排水导管的柔性接口构件接合的传感器组件。组件包括具有主体和从主体延伸的轴的传感器。接触构件与轴可滑动地配合并联接到柔性接口构件。弹性构件联接到传感器轴并且设置在接触构件和主体之间。致动器相对于排水导管在第一位置和第二位置之间移动传感器。在第一位置，传感器被定位成测量柔性界面构件处的压力和/或力，并且在第二位置，弹性构件在传感器上施加已知的力。

9. 发明申请

WO2014088886A1 CSF SHUNT FLOW EVALUATION APPARATUS AND METHOD USING A CONFORMABLE EXPANDED DYNAMIC RANGE THERMOSENSOR 审中-公开
标题翻译： CSF SHUNT FLOW EVALUATION设备和使用一个可扩展的动态范围热传感器的方法
公开(公告)号：WO2014088886A1
公开(公告)日：2014-06-12
申请号：PCT/US2013/071928
申请日：2013-11-26
申请人： FRITZ, Frederick, J. , SWOBODA, Marek , MATTIUCCI, Mark, E. , HOCHMAN, Matias, G. , SHUNTCHECK, INC.
发明人： FRITZ, Frederick, J. , SWOBODA, Marek , MATTIUCCI, Mark, E. , HOCHMAN, Matias, G.
IPC分类号： A61B5/03
CPC分类号： A61B5/01 , A61B5/015 , A61B5/031 , A61B5/032 , A61B5/14507 , A61B5/6833 , A61B5/684 , A61B2562/0271 , A61B2562/043 , A61M27/006
摘要： An apparatus and method that utilizes thermal dilution to detect a wide range of flow rates and/or flow status in cerebrospinal fluid (CSF) shunt systems. The use of a large cold source in combination with thermosensor pad of a particular construction provide a fluid flow analyzer with the ability to detect very low levels of CSF flow. In addition, a method for adjusting thermal dilution readings to compensate for varying shunt catheter depth is shown and for determining a steady state of the thermal dilution readings. The thermosensor pad is conformable to a patient's skin contour thereby making the apparatus and method less sensitive to ambient temperature errors and, as a result, more accurate in assessing CSF flow. Furthermore, a software error check is provided for identifying poor sensor-to-skin contact for alerting an operator to re-apply the thermosensor pad to correct, as well as a post-test check to determine if temperature data is reasonable before determining flow status or flow rate.
摘要翻译：利用热稀释来检测脑脊液（CSF）分流系统中的宽范围的流速和/或流动状态的装置和方法。使用大的冷源与特定结构的热传感器垫组合提供了具有检测非常低水平的CSF流量的能力的流体流量分析仪。此外，显示了用于调节热稀释读数以补偿不同分流导管深度的方法，并且用于确定热稀释读数的稳定状态。热传感器垫符合患者的皮肤轮廓，从而使装置和方法对环境温度误差的敏感性降低，结果在评估CSF流动方面更准确。此外，提供软件错误检查以识别差的传感器到皮肤接触，用于警告操作者重新应用热敏传感器垫以进行校正，以及在确定流量状态之前确定温度数据是否合理的测试后检查或流量。

10. 发明申请

WO2014007949A1 DRUG INFUSION WITH PRESSURE SENSING AND NON-CONTINUOUS FLOW WITH INDENTIFICATION OF AND INJECTION INTO FLUID-FILLED ANATOMIC SPACES 审中-公开
标题翻译：具有压力感测和不连续流动的药物输注，将其注入和注射到流体填充的解剖空间
公开(公告)号：WO2014007949A1
公开(公告)日：2014-01-09
申请号：PCT/US2013/045142
申请日：2013-06-11
申请人： MILLESTONE SCIENTIFIC, INC.
发明人： HOCHMAN, Mark, N.
IPC分类号： A61M5/00
CPC分类号： A61M5/168 , A61B5/032 , A61F9/0008 , A61M19/00 , A61M2205/581 , A61M2205/583 , G06F19/00 , G16H20/17
摘要： An automatic injection apparatus uses non-continuous fluid-flow of drugs to identify an intended injection site and includes a drive mechanism, a sensor and a controller for establishing fluid flow and pressure and preventing fluid flow until the pressure drops below a predetermined threshold. The pressure threshold is determined based on an internal pressure generated during an injection and more fluid will not flow until it drops below a predetermined pressure. An injection is performed to establish an initial pressure threshhold and then to stop the fluid flow into a patient until the pressure drops below a predetermined pressure which allows fluid flow to resume, thus identifying a fluid filled tissue space. The initial pressure threshold is used as a control parameter to a microprocessor below which controls the rate of injection. Fluid flows below certain pressures are also used to identify a specific location within the body during injections.
摘要翻译：自动注射装置使用药物的非连续流体流动来识别预期的注射部位，并且包括驱动机构，传感器和控制器，用于建立流体流动和压力并防止流体流动直到压力降低到预定阈值以下。压力阈值基于在注射期间产生的内部压力来确定，并且更多的流体将不会流动，直到其下降到预定压力以下。执行注射以建立初始压力阈值，然后停止流入患者的流体，直到压力下降到允许流体流动恢复的预定压力，从而识别流体填充的组织空间。初始压力阈值用作微处理器的控制参数，微处理器控制喷射速率。在某些压力以下的流体流动也用于在注射期间识别身体内的特定位置。

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