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1. 发明申请

WO2019136096A1 SYSTEMS AND METHODS FOR GUIDING A PATIENT OR A CAREGIVER THEROF 审中-公开
公开(公告)号：WO2019136096A1
公开(公告)日：2019-07-11
申请号：PCT/US2019/012092
申请日：2019-01-02
申请人： PREEME+YOU
发明人： REN, Yayu , ANDREWS, Bree Landis
IPC分类号： G16H15/00
CPC分类号： G16H80/00 , A61B5/0015 , A61B5/0205 , A61B5/044 , A61B5/7435 , A61B5/7465 , A61B2503/045 , G16H10/60 , G16H15/00
摘要： Methods for guiding a patient or a caregiver thereof along a medical trajectory associated with a medical problem of the patient include: (a) displaying, by a processor, at least one designating query to the patient and/or the caregiver, the at least one designating query designed to ascertain a severity level of a first biomarker associated with the medical problem; (b) receiving a response from the patient and/or the caregiver to the at least one designating query; (c) correlating the response to the at least one designating query with a severity level of the first biomarker; and (d) displaying a designated severity level of the first biomarker in a graphical format. Systems for guiding a patient or a caregiver thereof along a medical trajectory associated with a medical problem of the patient are described.

2. 发明申请

WO2018056811A1 WEARABLE DEVICE, METHOD AND SYSTEM FOR MONITORING ONE OR MORE VITAL SIGNS OF A HUMAN BODY 审中-公开
标题翻译：用于监视人体的一个或更多个重要标志的可佩戴装置，方法和系统
公开(公告)号：WO2018056811A1
公开(公告)日：2018-03-29
申请号：PCT/NL2017/050624
申请日：2017-09-20
申请人： BAMBI BELT HOLDING B.V.
发明人： BAMBANG OETOMO, Sidarto , TEN BHÖMER, Martijn , CAPARELLI, Claudia
IPC分类号： A61B5/0205 , A61B5/0408 , A61B5/0488 , A61B5/00 , A61B5/08 , A61B5/04
CPC分类号： A61B5/0205 , A61B5/04012 , A61B5/04085 , A61B5/0488 , A61B5/0803 , A61B5/0816 , A61B5/6804 , A61B5/6823 , A61B5/6831 , A61B5/7203 , A61B2503/045 , A61B2562/043
摘要： The present document describes a wearable device for monitoring one or more vital signs of a human body, the device comprising a carrier suitable for being worn around an abdominal part of the body, and an electrode arrangement comprising a plurality of conductive electrodes, wherein the electrodes are arranged on the carrier such as to be brought in contact with a skin of the body in use, and wherein the electrodes are arranged for receiving electric physiologic signals from the body for enabling monitoring of a membrane potential of one or more muscles in the body, wherein the electrodes comprise one or more first electrodes arranged on the carrier such as to be in contact with a side part of a torso of the body, such as to receive via said first electrodes a first electrical signal indicative of a membrane potential of a thoracic diaphragm of the body; wherein the carrier further comprises at least one second electrode in addition to the one or more first electrodes, the at least one second electrode being arranged on the carrier such as to be in contact with a mid front part of the abdominal part of the body, the at least one second electrode thereby being arranged for receiving a second electrical signal indicative of one or more further electric physiologic signals from the body, for enabling filtering of the first electrical signal using the second electrical signal for enabling electromyography of the thoracic diaphragm.
摘要翻译：本文件描述了一种用于监测人体的一个或多个生命体征的可佩戴装置，该装置包括适于佩戴在身体腹部周围的载体以及包括多个导电电极，其中所述电极布置在所述载体上以便与使用中的所述身体的皮肤接触，并且其中所述电极被布置用于接收来自所述身体的电生理信号，以能够监测膜电位，其中所述电极包括布置在所述载体上的一个或多个第一电极，以便与所述身体的躯干的侧部接触，例如以经由所述第一电极接收第一电气指示身体的胸膜的膜电位的信号; 其中除了所述一个或多个第一电极之外，所述载体还包括至少一个第二电极，所述至少一个第二电极布置在所述载体上以便与所述身体的所述腹部的中间前部接触，所述至少一个第二电极因此布置成用于接收指示来自身体的一个或多个其他电生理信号的第二电信号，以使得能够使用第二电信号对第一电信号进行滤波以用于使胸膜片肌电图成像。 / p>

3. 发明申请

WO2018053383A1 BIOMETRIC READING APPARATUS, SYSTEM AND METHOD OF USE THEREOF 审中-公开
标题翻译：生物计量读取装置，系统及其使用方法
公开(公告)号：WO2018053383A1
公开(公告)日：2018-03-22
申请号：PCT/US2017/051963
申请日：2017-09-18
申请人： WELCH, Gregory, P.
发明人： WELCH, Gregory, P.
IPC分类号： A61B5/02 , A61B5/0205 , A61B5/024
CPC分类号： A61B5/0404 , A61B5/00 , A61B5/0002 , A61B5/0006 , A61B5/0015 , A61B5/01 , A61B5/02055 , A61B5/0245 , A61B5/04085 , A61B5/0452 , A61B5/0816 , A61B5/14532 , A61B5/14551 , A61B5/6802 , A61B5/6823 , A61B5/6833 , A61B5/6838 , A61B2503/045 , A61B2560/0412 , A61B2560/045 , A61B2560/0468
摘要： Biometric sensor devices, systems and methods for obtaining biometric data and displaying biometric information based on the data on the sensor devices. The systems allow for additional biometric data collection and/or analysis through wireless communication capabilities. The devices and systems provide real-time information to the medical professional working on a patient. The information may be further based upon medical guidelines associated with the performed medical activity.
摘要翻译：生物特征传感器装置，系统和方法，用于获取生物特征数据并基于传感器装置上的数据显示生物特征信息。该系统允许通过无线通信功能进行额外的生物统计数据收集和/或分析。这些设备和系统为在病人身上工作的医学专业人员提供实时信息。该信息可以进一步基于与执行的医疗活动相关的医学指导。

4. 发明申请

WO2017055214A1 SECURE PULSE OXIMETER, MONITOR AND CLOUD CONNECTION 审中-公开
标题翻译：安全脉冲输出，监视和云连接
公开(公告)号：WO2017055214A1
公开(公告)日：2017-04-06
申请号：PCT/EP2016/072848
申请日：2016-09-26
申请人： KONINKLIJKE PHILIPS N.V.
发明人： CRONIN, John , GOGUEN, Jonathan , HUFFINES, Christopher
IPC分类号： A61B5/145 , A61B5/00 , G06F19/00 , H04L9/08
CPC分类号： A61B5/0022 , A61B5/02438 , A61B5/082 , A61B5/145 , A61B5/14532 , A61B5/14551 , A61B5/4842 , A61B2503/045 , A61B2505/01 , A61B2505/07 , G06F19/00 , G06F19/32 , G16H40/67 , H04L9/0662 , H04L9/0825 , H04L9/0894 , H04L9/3213
摘要： A method for transmitting and receiving pulse oximetry data comprising: transmitting pulse oximeter sensor data to a pulse oximeter monitor; encrypting the transmitted pulse oximeter data by the pulse oximeter monitor; transmitting the encrypted data to a cloud-based medical service; sending back the encrypted data from the cloud-based medical service to the pulse oximeter monitor, where the data is decrypted and displayed; 5 generating a random number by the pulse oximeter monitor via a random number generator that is triggered by a random number on the sensor, creating a unique ID for a device pulse oximeter monitor for a device; and sending the unique ID over the cloud for each event.
摘要翻译：一种用于发送和接收脉搏血氧饱和度数据的方法，包括：向脉搏血氧计监测器发送脉搏血氧计传感器数据; 通过脉搏血氧计监测器加密传输的脉搏血氧仪数据; 将加密的数据传输到基于云的医疗服务; 将加密的数据从基于云的医疗服务发送回脉搏血氧计监视器，数据被解密和显示; 5通过由传感器上的随机数触发的随机数发生器由脉搏血氧计监视器生成随机数，为装置创建用于装置脉搏血氧计监测器的唯一ID; 并为每个事件发送云上的唯一ID。

5. 发明申请

WO2017046103A1 METHOD AND APPARATUS FOR IMPROVED NEONATAL CARE 审中-公开
标题翻译：改善新生儿护理方法和装置
公开(公告)号：WO2017046103A1
公开(公告)日：2017-03-23
申请号：PCT/EP2016/071592
申请日：2016-09-13
申请人： KONINKLIJKE PHILIPS N.V.
发明人： MEFTAH, Mohammed , NIJSEN, Tamara, Mathea, Elisabeth
IPC分类号： A61G11/00 , A61B5/097 , G01N33/497
CPC分类号： A61B5/082 , A61B5/097 , A61B5/14507 , A61B5/7221 , A61B2503/045 , A61G11/00 , G01N2033/4975
摘要： Methods and apparatus are described herein for analyzing gas samples obtained from an interior of a neonatal incubator. In various embodiments, a neonatal gas analysis apparatus (110) may include: a gas sampler (112) to obtain one or more samples of gas from a neonatal incubator (100); a preconditioner (116) configured to capture, concentrate, and/or isolate various types of molecules from the one or more samples of gas; a gas analyzer (114) configured to analyze the isolated molecules and provide one or more signals of one or more health indicators based on the analysis; and/or a reliability indicator (128) to provide a signal indicative of reliability of the gas samples. In some embodiments, a user interface (126) may be provided to output indicative of the one or more health indicators. In some embodiments, a vital signs component (132) and/or an air quality controller (136) may also be provided.
摘要翻译：本文描述了用于分析从新生儿培养箱内部获得的气体样品的方法和装置。在各种实施例中，新生儿气体分析装置（110）可以包括：气体采样器（112），用于从新生儿孵化器（100）获得一个或多个气体样本; 配置成从气体的一个或多个样品捕获，浓缩和/或分离各种类型的分子的预处理器（116）气体分析器（114），其被配置为基于所述分析来分析所分离的分子并提供一个或多个健康指标的一个或多个信号; 和/或可靠性指示器（128），以提供指示气体样品的可靠性的信号。在一些实施例中，可以提供用户界面（126）以输出指示一个或多个健康指示符。在一些实施例中，还可以提供生命体征部件（132）和/或空气质量控制器（136）。

6. 发明申请

WO2016153472A1 ISOLETTE ENVIRONMENT CONTROLLER AND METHOD 审中-公开
标题翻译：隔离环境控制器和方法
公开(公告)号：WO2016153472A1
公开(公告)日：2016-09-29
申请号：PCT/US2015/021939
申请日：2015-03-23
申请人： ADVANCED IMAGING RESEARCH, INC.
发明人： SRINIVASAN, Ravi
IPC分类号： A61G11/00 , A61F7/00
CPC分类号： A61G11/006 , A61B5/0555 , A61B6/0428 , A61B2503/045 , A61F7/0053 , A61F7/007 , A61F2007/0055 , A61F2007/006 , A61F2007/0072 , A61F2007/0093 , A61F2007/0096 , A61G11/00 , A61G11/009 , A61G2203/20 , A61G2203/46 , A61G2210/50 , A61G2210/90
摘要： An apparatus and method of controlling a temperature within an isolette includes obtaining a temperature of ambient air external to the isolette, obtaining a base-line ambient air temperature, and calculating a maximum heater power level based on a relationship between the base-line ambient air temperature and the actual ambient air temperature.
摘要翻译：控制等离子体内的温度的装置和方法包括获得等离子体外部的环境空气的温度，获得基线环境空气温度，以及基于基线环境空气之间的关系来计算最大加热器功率水平温度和实际环境空气温度。

7. 发明申请

WO2016149107A1 SYSTEMS AND METHODS FOR MEASURING NEONATAL CEREBRAL OXYGENATION 审中-公开
标题翻译：用于测量新生儿谷氨酸氧化酶的系统和方法
公开(公告)号：WO2016149107A1
公开(公告)日：2016-09-22
申请号：PCT/US2016/022045
申请日：2016-03-11
申请人： BOARD OF REGENTS
发明人： ESENALIEV, Rinat, O. , PROUGH, Donald, S. , PETROV, Yuriy , PETROV, Irene, Y. , RICHARDSON, C., Joan
IPC分类号： A61B5/00
CPC分类号： A61B5/6803 , A61B5/0095 , A61B5/14542 , A61B2503/045
摘要： Disclosed herein are systems and methods for monitoring cerebral oxygenation that can be used to perform accurate, noninvasive measurement of cerebral venous blood oxygen saturation in neonatal patients. A neonatal cerebral oxygenation detection apparatus comprises a wearable support having a light emitter and an acoustic sensor coupled thereto. The wearable support can be secured onto a head of an infant, and the light emitter can be configured to emit a light signal toward a superior sagittal sinus of the infant's head. The acoustic sensor can be configured to detect acoustic pressure generated from the superior sagittal sinus when the superior sagittal sinus absorbs the light signal. Cerebral oxygenation can be determined based on the acoustic pressure detected by the acoustic detector.
摘要翻译：本文公开了用于监测脑氧合的系统和方法，其可用于对新生儿患者的脑静脉血氧饱和度进行准确的无创测量。新生儿脑氧合检测装置包括具有光发射器和耦合到其上的声学传感器的可穿戴支架。可佩戴支撑件可以固定在婴儿的头部上，并且发光器可被配置为朝向婴儿头部的上矢状窦发射光信号。声传感器可被配置为当上矢状窦吸收光信号时，检测从上矢状窦产生的声压。可以基于由声学检测器检测到的声压来确定脑氧合。

8. 发明申请

WO2016110786A1 SOLUBE FGFR3 DECOYS FOR TREATING SKELETAL GROWTH DISORDERS 审中-公开
标题翻译：用于治疗骨质增生疾病的溶解性FGFR3解决方案
公开(公告)号：WO2016110786A1
公开(公告)日：2016-07-14
申请号：PCT/IB2016/000403
申请日：2016-01-07
申请人： THERACHON , INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RESEARCH MEDICALE) , UNIVERSITY NICE SOPHIA ANTIPOLIS
发明人： GOUZE, Elvire , GARCIA, Stephanie
IPC分类号： C07K14/71 , A61K38/17 , A61P19/08
CPC分类号： C07K14/71 , A61B5/4538 , A61B5/4848 , A61B6/505 , A61B6/508 , A61B2503/045 , A61B2503/06 , A61B2503/40 , A61K9/0019 , A61K38/00 , A61K38/1709 , A61K38/179 , C07K14/47 , C07K2319/30 , C07K2319/32 , C07K2319/33 , C07K2319/43 , C07K2319/70 , Y02A50/401
摘要： The invention features soluble FGF decoy polypeptides and fusion polypeptides comprising an FGF decoy polypeptide linked to a heterologous polypeptide, such as an aggrecan binding protein. Both soluble FGF decoy polypeptides and fusion polypeptides can be used to prevent or treat skeletal disorders, such as achondroplasia.
摘要翻译：本发明的特征在于可溶性FGF诱饵多肽和包含与异源多肽例如聚集蛋白聚糖结合蛋白连接的FGF诱饵多肽的融合多肽。可溶性FGF诱饵多肽和融合多肽均可用于预防或治疗诸如软骨发育不良的骨骼疾病。

9. 发明申请

WO2015142603A1 DETECTION OF AORTIC COARCTATION USING PHOTOPLETHYSMOGRAPHY 审中-公开
标题翻译：使用光学显微镜的检测
公开(公告)号：WO2015142603A1
公开(公告)日：2015-09-24
申请号：PCT/US2015/020077
申请日：2015-03-12
申请人： THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH , JERUSALEM COLLEGE OF TECHNOLOGY
发明人： KOPPEL, Robert , NITZAN, Meir
IPC分类号： A61B5/021
CPC分类号： A61B5/02007 , A61B5/02427 , A61B5/0261 , A61B5/0295 , A61B5/14551 , A61B5/6825 , A61B5/6829 , A61B5/7203 , A61B5/7207 , A61B5/7246 , A61B5/725 , A61B5/7275 , A61B2503/04 , A61B2503/045 , G06F19/00
摘要： Methods and systems are described for detecting the likelihood of an aortic coarctation in an infant using photoplethysmographic pulse signals obtained from the hand and foot of the infant.
摘要翻译：描述了使用从婴儿的手和脚获得的光电体积描记术脉冲信号来检测婴儿中主动脉缩窄的可能性的方法和系统。

10. 发明申请

WO2015029044A3 INCUBATOR WITH A NOISE MUFFLING MECHANISM AND METHOD THEREOF 审中-公开
标题翻译：具有噪声消除机制的吸入器及其方法
公开(公告)号：WO2015029044A3
公开(公告)日：2015-07-23
申请号：PCT/IL2014050785
申请日：2014-09-02
申请人： ASPECT IMAGING LTD
发明人： RAPOPORT URI
IPC分类号： G10K11/175 , A61F7/00 , A61G11/00 , G01H3/14 , G10K11/162 , G10K11/168 , G10K11/20
CPC分类号： A61F7/0053 , A61B5/0555 , A61B2503/045 , A61F2007/0054 , A61F2007/0055 , A61F2007/0057 , A61F2007/006 , A61F2007/0093 , A61F2007/0095 , A61G11/00 , A61G11/009 , A61G2200/14 , A61G2203/30 , A61G2203/36 , A61G2203/44 , A61G2203/46 , A61G2203/70 , A61G2210/50 , A61M16/0003 , A61M16/105 , A61M16/161 , A61M2016/0027 , A61M2205/0233 , A61M2205/3633 , A61M2205/42 , G01H3/14 , G10K11/162 , G10K11/168 , G10K11/172 , G10K11/175 , G10K11/20 , G10K2210/116 , G10K2210/118 , G10K2210/129 , G10K2210/301 , G10K2210/3223 , G10K2210/3224 , G10K2210/509
摘要： A noise-attenuating neonate incubator (NANI) comprising sound attenuating module (SAM) configured to decrease the ratio, (AmpRatt_i), of the sound's amplitude at a time, t_i, to a reference amplitude, to a critical amplitude ratio value of said sound measured over a predetermined time, At, (AmpRQVΔt) or less. The SAM comprises passive noise attenuating, active noise attenuating or both. A method for sound attenuating a neonate incubator,characterized by: (a) obtaining a noise-attenuating neonate incubator (NANI) comprising sound attenuating module (SAM) configured to decrease AmpRatt_i to AmpRQVΔtor less; (b) accommodating said neonate in said NANI; and, (c) attenuating said noise by said at least one SAM, thereby changing the sound signature.
摘要翻译：一种噪声衰减的新生儿培养箱（NANI），包括声音衰减模块（SAM），其被配置为将一次的声音振幅t_i的比值（AmpRatt_i）降低到参考振幅，达到所述声音的临界幅度比值在预定时间At（AmpRQVΔt）以下测量。 SAM包括被动噪声衰减，有源噪声衰减或两者。一种用于声音衰减新生儿培养箱的方法，其特征在于：（a）获得包含声音衰减模块（SAM）的噪声衰减新生儿培养箱（NANI），其配置为将AmpRatt_i减小到AmpRQVΔtor; （b）在所述NANI中容纳所述新生儿; 和（c）通过所述至少一个SAM衰减所述噪声，从而改变声音签名。

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