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1. 发明申请

WO2017046103A1 METHOD AND APPARATUS FOR IMPROVED NEONATAL CARE 审中-公开
标题翻译：改善新生儿护理方法和装置
公开(公告)号：WO2017046103A1
公开(公告)日：2017-03-23
申请号：PCT/EP2016/071592
申请日：2016-09-13
申请人： KONINKLIJKE PHILIPS N.V.
发明人： MEFTAH, Mohammed , NIJSEN, Tamara, Mathea, Elisabeth
IPC分类号： A61G11/00 , A61B5/097 , G01N33/497
CPC分类号： A61B5/082 , A61B5/097 , A61B5/14507 , A61B5/7221 , A61B2503/045 , A61G11/00 , G01N2033/4975
摘要： Methods and apparatus are described herein for analyzing gas samples obtained from an interior of a neonatal incubator. In various embodiments, a neonatal gas analysis apparatus (110) may include: a gas sampler (112) to obtain one or more samples of gas from a neonatal incubator (100); a preconditioner (116) configured to capture, concentrate, and/or isolate various types of molecules from the one or more samples of gas; a gas analyzer (114) configured to analyze the isolated molecules and provide one or more signals of one or more health indicators based on the analysis; and/or a reliability indicator (128) to provide a signal indicative of reliability of the gas samples. In some embodiments, a user interface (126) may be provided to output indicative of the one or more health indicators. In some embodiments, a vital signs component (132) and/or an air quality controller (136) may also be provided.
摘要翻译：本文描述了用于分析从新生儿培养箱内部获得的气体样品的方法和装置。在各种实施例中，新生儿气体分析装置（110）可以包括：气体采样器（112），用于从新生儿孵化器（100）获得一个或多个气体样本; 配置成从气体的一个或多个样品捕获，浓缩和/或分离各种类型的分子的预处理器（116）气体分析器（114），其被配置为基于所述分析来分析所分离的分子并提供一个或多个健康指标的一个或多个信号; 和/或可靠性指示器（128），以提供指示气体样品的可靠性的信号。在一些实施例中，可以提供用户界面（126）以输出指示一个或多个健康指示符。在一些实施例中，还可以提供生命体征部件（132）和/或空气质量控制器（136）。

2. 发明申请

WO2021122672A1 A COUGH DETECTION SYSTEM AND METHOD 审中-公开
公开(公告)号：WO2021122672A1
公开(公告)日：2021-06-24
申请号：PCT/EP2020/086322
申请日：2020-12-16
申请人： KONINKLIJKE PHILIPS N.V.
发明人： DEN BRINKER, Albertus, Cornelis , PRIORI, Rita , NIJSEN, Tamara, Mathea, Elisabeth , DELLIMORE, Kiran, Hamilton, J.
IPC分类号： G16H50/20
摘要： A cough detection system and method uses a first database of physiological information relating to a user for whom cough detection is to be implemented and relating to other people likely to be in the vicinity of the user. A second database (used in real time or as a part of a system calibration) has cough data associated with the physiological information. There is a set of cough detection algorithms, each one tailored to a particular set of physiological characteristics. A cough detection algorithm is selected or constructed which is suitable for identifying coughs of the user while ignoring coughs of the other people. This selected algorithm is applied to sound collected to identify coughs of the user.

3. 发明申请

WO2018134214A1 ALIGNMENT OF BREATH SAMPLE DATA FOR DATABASE COMPARISONS 审中-公开
公开(公告)号：WO2018134214A1
公开(公告)日：2018-07-26
申请号：PCT/EP2018/051039
申请日：2018-01-17
申请人： KONINKLIJKE PHILIPS N.V.
发明人： WEDA, Johannes , VINK, Teunis, Johannes , KNOBEL, Hugo, Hubertus , NIJSEN, Tamara, Mathea, Elisabeth
IPC分类号： A61B5/00 , G01N33/00 , G01N27/62 , G01N33/497 , G01N30/86 , A61B5/08
摘要： A method (RT_A) for synchronizing data for a plurality of gas samples, e.g. breath samples, with volatile organic compounds. The data comprises chromatographic data indicative of molecule elution times, and preferably also mass spectrography data. The method comprises identifying or selecting (I_MM) marker molecules, e.g. 5-20 molecules, preferably easily identifiable molecues for each of the plurality of gas samples, and clustering (CL) the plurality of gas samples into a plurality of clusters according to a clustering criterion, e.g. including additional information such as time of obtaining the data and/or analzing equipment used. Next, a first correction of retention time deviations (P_C1) is performed on the data for the gas samples between clusters by using the marker molecules as anchor points, so as to provide a coarse reduction of retention time deviations (d) between the data for the gas samples. Finally, a second correction of retention time deviations (P_C2) on the data for the gas samples, so as to further reduce retention time deviations (d) between the data for the gas samples, e.g. by using standard software packages. The method can reduce significant retention time deviations so as to allow e.g. breath sample fingerprints obtained by different equipment at different periods of time to be compared in one database for use on a digital platform (DP) such as the HSDP.

4. 发明申请

WO2017032635A1 SYSTEM, METHOD AND COMPUTER PROGRAM FOR PROVIDING A HEALTH ADVICE TO A SUBJECT 审中-公开
标题翻译：用于向主体提供健康建议的系统，方法和计算机程序
公开(公告)号：WO2017032635A1
公开(公告)日：2017-03-02
申请号：PCT/EP2016/069366
申请日：2016-08-16
申请人： KONINKLIJKE PHILIPS N.V.
发明人： SAINI, Privender, Kaur , DEKKER, Marian , STUT, Wilhelmus, Johannes, Joseph , PRIORI, Rita , BARRETTO, Chevone, Marie , XANTHOPOULAKIS, Charalampos , SCHONENBERG, Maartje, Helena , NIJSEN, Tamara, Mathea, Elisabeth , VAN GENUGTEN, Lenneke , KLEE, Mareike
IPC分类号： A61B5/11 , G06F19/00 , A61B5/00
CPC分类号： A61B5/1118 , A61B5/0002 , A61B5/486 , A61B5/6895 , A61B5/743 , A61B2505/09 , G06F19/00 , G16H20/30 , G16H50/20
摘要： The invention relates to a system (200), mobile device (210), processing device (220), method (700) and computer program for providing a health advice to a subject. An activity sensor (211) determines a subject's activity level (211a) during a first time period. An activity evaluation unit (221) compares the activity level (211a) to at least one activity threshold. A categorization unit (212) enables the subject to assign an activity to said first time period. An advice providing unit (222) provides a health advice to the subject based on the activity evaluation unit's comparison and on the assigned activity. The system (200) is not limited to activity sensing but can also comprise other sensors of other vital parameters such as, e.g., heart rate, respiration rate, blood pressure, glucose level, etc.
摘要翻译：本发明涉及系统（200），移动设备（210），处理设备（220），方法（700）和用于向对象提供健康建议的计算机程序。活动传感器（211）在第一时间段期间确定受试者的活动水平（211a）。活动评估单元（221）将活动水平（211a）与至少一个活动阈值进行比较。分类单元（212）使得受试者能够将活动分配给所述第一时间段。咨询提供单元（222）基于活动评估单元的比较和所分配的活动向受试者提供健康建议。系统（200）不限于活动感测，而是还可以包括其他生物参数的其他传感器，例如心率，呼吸速率，血压，葡萄糖水平等。

5. 发明申请

WO2020109424A1 GAS ANALYSIS SAMPLING WITH OVERLOAD DETECTION 审中-公开
公开(公告)号：WO2020109424A1
公开(公告)日：2020-06-04
申请号：PCT/EP2019/082806
申请日：2019-11-27
申请人： KONINKLIJKE PHILIPS N.V.
发明人： WEDA, Johannes , NIJSEN, Tamara, Mathea, Elisabeth , KNOBEL, Hugo, Hubertus , KLOOTWIJK, Johan, Hendrik , VERSCHUEREN, Alwin, Rogier, Martijn
IPC分类号： G01N30/02 , G01N30/46 , G01N30/78 , G01N33/00 , G01N33/497
摘要： A gas sampling device suited for e.g. sampling of exhaled breath from a subject in a sorbent tube (T) with volatile organic compound (VOC) from a gas sample (G_S) received at a gas inlet (G_I). A gas circuit (GC) provides a flow path from the gas inlet (G_I) to a port (P) where the sorbent tube (T) is connected, so as to allow the gas sample (G_S) to load the sorbent tube (T). A VOC detector (DT1) in the flow path serves to detect VOC concentration during the sampling process. A control module (CM) continuously calculates a measure of cumultative sum of VOCs based on the output from the VOC detector (DT1), and this measure is then compared with a predetermined threshold value (TH). When the measure exceeds the threshold value (TH), the control module (CM) generates an output (O), and the sampling process is then preferably stopped accordingly, e.g. by controlling a pump or value in the flow path to stop gas flow in response to the output (O). Such device can eliminate the problem with overloading of sorbent tubes, which leads to invalid gas measurements that needs to be redone. Thus, the device can save time, costs, and risks.

6. 发明申请

WO2018011113A1 SYSTEM AND METHOD FOR MONITORING ASTHMA SYMPTOMS 审中-公开
标题翻译：用于监测哮喘症状的系统和方法
公开(公告)号：WO2018011113A1
公开(公告)日：2018-01-18
申请号：PCT/EP2017/067204
申请日：2017-07-10
申请人： KONINKLIJKE PHILIPS N.V.
发明人： PRITCHARD, John, Nigel , KLEE, Mareike , DEN BRINKER, Albertus, Cornelis , WILLARD, Nicolaas, Petrus , HILBIG, Rainer , DEKKER, Marian , NIJSEN, Tamara, Mathea, Elisabeth , HOOGEWERF, Hanneke
IPC分类号： A61B5/00 , A61B7/00 , A61B5/08 , A61B5/11 , G06F19/00
摘要： The present invention relates to a system for monitoring asthma symptoms of a subject (12), comprising a monitoring unit (14) configured to monitor at least one objective asthma symptom of the subject, an analysis unit (16) configured to determine an asthma status of the subject based on the at least one objective asthma symptom monitored by the monitoring unit, a test unit (18) configured to provide a test for collecting subjective asthma symptoms from the subject, if the at least one objective asthma symptom monitored by the monitoring unit (14) has changed in a manner that the change reveals a deterioration of the asthma status of the subject. Further the system comprises a calibration unit (24) configured to calibrate the at least one objective asthma symptom gathered from the subject with respect to a calibration test, wherein the calibration unit (24) is arranged to perform calibration at least once during an initial phase of use of the system (10).
摘要翻译：本发明涉及用于监测受试者的哮喘症状的系统（12），其包括监测单元（14），其配置成监测受试者的至少一种客观哮喘症状，分析单元（被配置为基于由所述监测单元监测到的所述至少一种客观哮喘症状来确定所述受试者的哮喘状态;测试单元（18），其被配置为提供用于从所述受试者收集主观哮喘症状的测试，如果所述至少一种由监测单元（14）监测的一种客观哮喘症状以改变显示受试者的哮喘状态恶化的方式改变。此外，所述系统包括校准单元（24），所述校准单元（24）被配置为校准从所述对象收集的关于校准测试的所述至少一个客观哮喘症状，其中所述校准单元（24）被布置成在初始阶段期间执行至少一次校准使用系统（10）。

7. 发明申请

WO2017216079A1 COMPACT GAS ANALYSIS DEVICE AND METHOD 审中-公开
标题翻译：紧凑型气体分析装置和方法
公开(公告)号：WO2017216079A1
公开(公告)日：2017-12-21
申请号：PCT/EP2017/064210
申请日：2017-06-12
申请人： KONINKLIJKE PHILIPS N.V.
发明人： NIJSEN, Tamara, Mathea, Elisabeth , WEDA, Johannes
IPC分类号： G01N33/00 , G01N33/497 , G01N30/60 , G01N30/62 , G01N30/02 , G01N30/88
摘要： A gas analysis device suited for e.g. medical analysis of exhaled breath from a subject. A gas inlet receives a gas sample to a flow path for guiding the gas sample to two or more gas separators, e.g. gaschromatography columns, with respective molecule selectivity properties which are different. One or more detectors, each with a sensor, are arranged to generate respective responses to outputs from the two or more gas separators. A communication module generate output data in response to the respective responses from the one or more detectors, e.g. data indicative of selected molecules in the gas sample, e.g. data indicative of one or more diseases identified as a result of idenfitied biomarkers in the gas sample. The device is suitable as a compact device, e.g. a handheld breath analysis device, since the use of a plurality of gas separators allows use of very molecule specific gas separators which can be implemented with a small size. E.g. a flow path with several parallel paths each comprising one or more gas separator may be used.
摘要翻译：气体分析装置适用于例如气体分析装置。对某个主题呼出气的医学分析。气体入口将气体样品接收到流动路径以将气体样品引导到两个或更多个气体分离器，例如气体分离器。气相色谱柱，其各自的分子选择性性质不同。每个具有传感器的一个或多个检测器被布置为对来自两个或更多个气体分离器的输出产生各自的响应。通信模块响应于来自一个或多个检测器的相应响应而产生输出数据，例如，指示气体样品中所选分子的数据，例如，指示由于气体样品中的识别的生物标志物而鉴定的一种或多种疾病的数据。该设备适合作为紧凑设备，例如，手持式呼吸分析装置，因为使用多个气体分离器允许使用可以以小尺寸实施的非常分子特定的气体分离器。例如。可以使用具有多个平行路径的流路，每个平行路径包含一个或多个气体分离器。

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