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1. 发明申请

WO2021053676A1 ELECTRICAL SUBSTANCE CLEARANCE FROM THE BRAIN 审中-公开
公开(公告)号：WO2021053676A1
公开(公告)日：2021-03-25
申请号：PCT/IL2020/051022
申请日：2020-09-17
申请人： RAINBOW MEDICAL LTD.
发明人： GROSS, Yossi , TENDLER, Alex
IPC分类号： A61N1/05 , A61N1/32 , A61N1/36 , A61N1/30
摘要： Apparatus is provided that includes a two-dimensional arrangement (70) of extracranial electrodes (30), configured to be placed outside and in electrical contact with a skull of a subject identified as at risk of or suffering from a disease; and a cerebrospinal fluid (CSF) electrode (32), configured to be implanted in a ventricular system of a brain of the subject. Control circuitry is configured to drive the extracranial and the CSF electrodes (30, 32) to clear a substance from brain parenchyma of the subject into at least one region of the brain selected from the group consisting of: a subarachnoid space of the brain and dural sinuses of the brain. Other embodiments are also described.

2. 发明申请

WO2018122834A1 ACCOMMODATIVE INTRAOCULAR LENS 审中-公开
公开(公告)号：WO2018122834A1
公开(公告)日：2018-07-05
申请号：PCT/IL2017/051317
申请日：2017-12-05
申请人： RAINBOW MEDICAL LTD.
发明人： SOHN, Zev , GROSS, Yossi
IPC分类号： A61F2/16
摘要： An accommodating intraocular lens implant (10) is provided that is shaped so as to be assemblable into an assembled state in situ in a capsular bag of a human eye, and includes an anterior floating lens unit (24), which comprises an anterior lens (26); a posterior lens unit (50), which comprises a posterior lens (52); an anterior rim (44); levers (30), arranged to move the anterior floating lens unit (24) toward and away from the anterior rim (44), in an anterior-posterior direction; and a circumferential rim (48), which is attached to the levers (30). The lens implant (10) is arranged such that in the assemble state: elastic potential energy is stored in the lens implant (10) as a result of deformation of the lens implant (10) during a transition from a fully- accommodated state to a fully- unaccommodated state, and at least 50% of the elastic potential energy stored in the lens implant (10) as the result of the deformation is stored in the circumferential rim (48).

3. 发明申请

WO2014068577A3 CONTROLLED TISSUE ABLATION 审中-公开
标题翻译：控制组织消融
公开(公告)号：WO2014068577A3
公开(公告)日：2014-06-26
申请号：PCT/IL2013050903
申请日：2013-11-03
申请人： RAINBOW MEDICAL LTD
发明人： GROSS YOSSI
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B5/0215 , A61B2018/0016 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00642 , A61B2018/00672 , A61B2018/00678 , A61B2018/00708 , A61B2018/0072 , A61B2018/00839 , A61B2018/00863 , A61B2018/00994 , A61B2018/1467 , A61N1/36071 , A61N1/36117
摘要： A catheter (28) has a distal portion that comprises an electrode unit (22) and an ablation unit (24). A control unit (32) is configured: (i) to receive a preliminary blood pressure value (BPV), (ii) to receive a target excited BPV, (iii) to iteratively: (a) drive the electrode unit to apply an excitatory current to nerve of a renal artery (8), (b) receive a detected excited BPV, and (c) alter a value of a property of the excitatory current, until the detected excited BPV crosses a first threshold, and (iv) subsequently, to iteratively: (d) drive the ablation unit to apply ablating energy to the nerve, (e) subsequently, drive the electrode unit to apply a selected excitatory current to the nerve, and (f) receive a detected ablated BPV, until the detected ablated BPV crosses a second threshold. Other embodiments are also described.
摘要翻译：导管（28）具有包括电极单元（22）和消融单元（24）的远端部分。控制单元（32）被配置为：（i）接收初步血压值（BPV），（ii）接收目标激励BPV，（iii）迭代地：（a）驱动电极单元施加兴奋剂（8），（b）接收检测到的激发的BPV，和（c）改变兴奋性电流的性质的值，直到检测到的激发的BPV跨越第一阈值，和（iv）随后（d）驱动消融单元向神经施加消融能量，（e）随后驱动电极单元向神经施加选定的兴奋电流，和（f）接收检测到的消融BPV，直到检测到的消融BPV跨越第二阈值。还描述了其它实施例。

4. 发明申请

WO2013111137A2 WIRELESS NEURQSTIMULATQRS 审中-公开
标题翻译：无线NEURQSTIMULATQRS
公开(公告)号：WO2013111137A2
公开(公告)日：2013-08-01
申请号：PCT/IL2013050069
申请日：2013-01-24
申请人： RAINBOW MEDICAL LTD , GROSS YOSSI , NEEMAN DANY , ORON GUR , RONEN SHLOMO , STERN-COHEN ALI
发明人： GROSS YOSSI , NEEMAN DANY , ORON GUR , RONEN SHLOMO , STERN-COHEN ALI
IPC分类号： A61N5/02
CPC分类号： A61H23/00 , A61N1/0556 , A61N1/36067 , A61N1/36071 , A61N1/36139 , A61N1/36167 , A61N1/37205 , A61N1/37288 , A61N1/3787 , A61N5/022 , A61N5/04
摘要： Apparatus for applying a treatment (216) to at least one tissue of a subject is described, the apparatus comprising a transmitting unit (210) configured to transmit a wireless power signal (214), a first implant (202a), and a second implant (202b), each of the implants being configured to receive the power signal and to apply the treatment asynchronously to each other, in response to the power signal. Other embodiments are also described.
摘要翻译：描述了用于对受试者的至少一个组织施加治疗（216）的装置，所述装置包括：发射单元（210），被配置为发射无线功率信号（214），第一植入物（202a）和第二植入物（202b），每个所述植入物被配置为响应于所述功率信号而接收所述功率信号并将所述治疗异步地施加于彼此。还描述了其它实施例。

5. 发明申请

WO2011083491A2 ALVEOLAR RIDGE AUGMENTATION 审中-公开
标题翻译： ALVEOLAR RIDGE增强
公开(公告)号：WO2011083491A2
公开(公告)日：2011-07-14
申请号：PCT/IN2010/000975
申请日：2010-11-22
申请人： RAINBOW MEDICAL LTD. , BETTER, Hadar , FOSTICK, Gideon , GROSS, Yossi
发明人： BETTER, Hadar , FOSTICK, Gideon , GROSS, Yossi
IPC分类号： A61C17/16
CPC分类号： A61C8/0006 , A61B17/24 , A61B17/32 , A61B17/3209 , A61B18/14 , A61B18/20 , A61B2017/0647 , A61B2017/0648 , A61B2017/3225 , A61B2018/144 , A61B2018/1467 , A61N7/02
摘要： Apparatus is provided for use with a gingival periosteum (230) lining a bone. The apparatus comprises a periosteal mesher (200), which comprises a mesher surface (210), and a plurality of cutting elements (212) distributed over the mesher surface (210), which are configured to cut the gingival periosteum (230) to increase flexibility thereof. Other embodiments are also described.
摘要翻译：提供了用于衬有骨的齿龈骨膜（230）的装置。该设备包括具有网格表面（210）的骨膜网格（200）和分布在网格表面（210）上的多个切割元件（212），其被配置为切割牙龈骨膜（230）以增加其灵活性。还描述了其他实施例。

6. 发明申请

WO2009095920A3 INTRA-AORTIC ELECTRICAL COUNTERPULSATION 审中-公开
标题翻译：内部电动计数器
公开(公告)号：WO2009095920A3
公开(公告)日：2010-03-11
申请号：PCT/IL2009000117
申请日：2009-01-29
申请人： RAINBOW MEDICAL LTD , GROSS YOSSI , DAGAN AMIR
发明人： GROSS YOSSI , DAGAN AMIR
IPC分类号： A61B5/04
CPC分类号： A61N1/36114 , A61N1/05 , A61N1/36564 , A61N1/3962
摘要： In some embodiments of the present invention, apparatus is provided, including a sensing electrode (22) configured to be implanted at a non-cardiac site in a vicinity of an aorta (24) of a subject and to detect an electrical parameter of the aorta, and a control unit (26) configured to receive the detected parameter and to generate an output in response to the detected parameter. Additional embodiments are also described.
摘要翻译：在本发明的一些实施例中，提供了一种设备，包括被配置为植入在受试者的主动脉（24）附近的非心脏部位并且检测主动脉的电参数的感测电极（22），以及控制单元（26），被配置为接收检测到的参数并且响应于检测到的参数而生成输出。还描述了另外的实施例。

7. 发明申请

WO2009095920A2 INTRA-AORTIC ELECTRICAL COUNTERPULSATION 审中-公开
标题翻译：内部电动计数器
公开(公告)号：WO2009095920A2
公开(公告)日：2009-08-06
申请号：PCT/IL2009/000117
申请日：2009-01-29
申请人： RAINBOW MEDICAL LTD. , GROSS, Yossi , DAGAN, Amir
发明人： GROSS, Yossi , DAGAN, Amir
IPC分类号： A61N1/05
CPC分类号： A61N1/36114 , A61N1/05 , A61N1/36564 , A61N1/3962
摘要： In some embodiments of the present invention, apparatus is provided, including a sensing electrode (22) configured to be implanted at a non-cardiac site in a vicinity of an aorta (24) of a subject and to detect an electrical parameter of the aorta, and a control unit (26) configured to receive the detected parameter and to generate an output in response to the detected parameter. Additional embodiments are also described.
摘要翻译：在本发明的一些实施例中，提供了一种设备，包括被配置为植入在受试者的主动脉（24）附近的非心脏部位并且检测主动脉的电参数的感测电极（22），以及控制单元（26），被配置为接收检测到的参数并且响应于检测到的参数而生成输出。还描述了另外的实施例。

8. 发明申请

WO2017208230A1 ACCOMMODATIVE INTRAOCULAR LENS 审中-公开
标题翻译：适应性人工晶状体
公开(公告)号：WO2017208230A1
公开(公告)日：2017-12-07
申请号：PCT/IL2017/050594
申请日：2017-05-29
申请人： RAINBOW MEDICAL LTD.
发明人： SOHN, Zev , GROSS, Yossi
IPC分类号： A61F2/16
摘要： An accommodating intraocular lens implant (10) includes an anterior floating lens unit (24), which includes an anterior lens (26); a posterior lens unit (50), which includes a posterior lens (52); an anterior rim complex (44); levers (30); and a ring (100). The levers (30) are (a) (i) in jointed connection with the anterior floating lens unit (24) at respective first longitudinal sites (60) along the levers (30), (ii) in pivotable connection with the anterior rim complex (44) at respective second longitudinal sites (62) along the levers (30), and (iii) in pivotable contact with the posterior lens unit (50) at respective third longitudinal sites (64) along the levers (30), and (b) arranged to move the anterior floating lens unit (24) toward and away from the anterior rim complex (44), in an anterior- posterior direction. The ring (100) has a diameter greater than that of the anterior lens (26), and is connected to the levers (30). The lens implant (10) is configured such that the ring (100) deforms during a transition of the lens implant (10) between a fully- accommodated state and a fully-unaccommodated state.
摘要翻译：可调节的人工晶状体植入物（10）包括前部浮动透镜单元（24），其包括前部透镜（26）; 后透镜单元（50），其包括后透镜（52）;后透镜单元前缘复合体（44）; 杠杆（30）; 和一个环（100）。杠杆（30）是（a）（i）在沿杠杆（30）的相应第一纵向位置（60）处与前部浮动透镜单元（24）接合连接，（ii）与前部边缘复合体（30）处的相应的第二纵向位置（62）处，以及（iii）在沿着所述杠杆（30）的相应的第三纵向位置（64）处与所述后透镜单元（50）枢转接触，以及 b）布置成沿前 - 后方向将前部浮动透镜单元（24）朝向和远离前部边缘复合体（44）移动。环（100）的直径大于前透镜（26）的直径，并连接到杠杆（30）。所述晶状体植入物（10）被配置为使得所述环（100）在所述晶状体植入物（10）在完全容纳状态和完全未适应状态之间转变期间变形。

9. 发明申请

WO2015170281A1 CONTROLLED TISSUE ABLATION TECHNIQUES 审中-公开
标题翻译：控制组织抽搐技术
公开(公告)号：WO2015170281A1
公开(公告)日：2015-11-12
申请号：PCT/IB2015/053350
申请日：2015-05-07
申请人： RAINBOW MEDICAL LTD
发明人： GROSS, Yossi , MEIRY, Gideon , ZADOK, Yehuda
IPC分类号： A61B18/14 , A61N1/36
CPC分类号： A61B18/1492 , A61B5/021 , A61B5/4836 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00642 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00839 , A61B2018/00863 , A61N1/0551 , A61N1/36007 , A61N1/36017 , A61N1/36117 , A61N1/36135 , G02B6/1228 , G02B6/136 , G02B6/305 , G02B2006/12061
摘要： Apparatus and methods are described, including a method for use with tissue of a renal nerve (770) passing longitudinally within a wall of a renal artery (8) of a subject. Using one or more stimulating electrodes (850a, 850b) disposed within the renal artery, the tissue is stimulated by passing a stimulating current through the wall of the renal 5 artery. Using a sensor (26), a rate of change of blood pressure of the subject is sensed, following the start of the stimulation of the tissue. In response to the rate of change, it is decided whether to ablate the tissue, and in response to deciding to ablate the tissue, the tissue is ablated. Other applications are also described.
摘要翻译：描述了装置和方法，包括与受试者的肾动脉（8）的壁内纵向通过的肾神经组织（770）一起使用的方法。使用设置在肾动脉内的一个或多个刺激电极（850a，850b），通过使刺激电流通过肾脏5动脉的壁来刺激组织。使用传感器（26），在组织的刺激开始之后，感测对象的血压变化率。响应于变化率，决定是否消融组织，并且响应于决定烧蚀组织，消融组织。还描述了其它应用。

10. 发明申请

WO2014068563A1 PNEUMATIC MEDICAL MOTORS FOR A SURGICAL CONTROLLER 审中-公开
标题翻译：用于外科手术的气动医用电动机
公开(公告)号：WO2014068563A1
公开(公告)日：2014-05-08
申请号：PCT/IL2013/050887
申请日：2013-10-30
申请人： RAINBOW MEDICAL LTD.
发明人： SOHN, Zev , GROSS, Yossi , KINROT, Opher
IPC分类号： A61M25/01 , A61M25/082 , A61M25/10
CPC分类号： A61B17/00234 , A61B17/00 , A61B17/0218 , A61B17/1628 , A61B17/17 , A61B17/320016 , A61B34/30 , A61B90/00 , A61B90/37 , A61B90/50 , A61B90/57 , A61B2017/00203 , A61B2017/00216 , A61B2017/00296 , A61B2017/00398 , A61B2017/00544
摘要： Apparatus is provided, comprising first and second rails (140) and a pneumatic motor assembly (22). The assembly comprises a first motor subassembly (180), comprising a first- motor subassembly locking balloon (160), which locks the first rail to the first motor subassembly by inflation thereof; and a first-motor subassembly moving balloon (170), which moves the first rail by a mechanism of either inflation or deflation of the first-motor subassembly moving balloon, when the first-motor locking balloon is inflated. Assembly (22) additionally comprises a second motor subassembly (185), comprising a second-motor assembly locking balloon (165), which locks the second rail to the second motor subassembly by inflation thereof; and a second-motor subassembly moving balloon (175), configured to move the second rail by a mechanism selected from either inflation or deflation of the second-motor subassembly moving balloon, when the second-motor subassembly locking balloon is inflated. Other applications are also provided.
摘要翻译：提供了包括第一和第二轨道（140）和气动马达组件（22）的设备。组件包括第一电动机子组件（180），其包括第一电动机子组件锁定球囊（160），其通过其膨胀将第一轨道锁定到第一电动机子组件; 以及当所述第一电动机锁定气囊膨胀时，所述第一电动机子组件移动气囊（170）通过所述第一电动机子组件移动气囊的充气或放气的机构移动所述第一轨道。组件（22）还包括第二电动机子组件（185），其包括第二电动机组件锁定球囊（165），其通过其膨胀将第二轨道锁定到第二电动机子组件; 以及第二电动机子组件移动气囊（175），其构造成当所述第二电动机子组件锁定气囊膨胀时，通过选自所述第二电动机子组件移动气囊的充气或放气的机构来移动所述第二轨道。还提供其他应用。

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