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1. 发明申请

WO2021053676A1 ELECTRICAL SUBSTANCE CLEARANCE FROM THE BRAIN 审中-公开
公开(公告)号：WO2021053676A1
公开(公告)日：2021-03-25
申请号：PCT/IL2020/051022
申请日：2020-09-17
申请人： RAINBOW MEDICAL LTD.
发明人： GROSS, Yossi , TENDLER, Alex
IPC分类号： A61N1/05 , A61N1/32 , A61N1/36 , A61N1/30
摘要： Apparatus is provided that includes a two-dimensional arrangement (70) of extracranial electrodes (30), configured to be placed outside and in electrical contact with a skull of a subject identified as at risk of or suffering from a disease; and a cerebrospinal fluid (CSF) electrode (32), configured to be implanted in a ventricular system of a brain of the subject. Control circuitry is configured to drive the extracranial and the CSF electrodes (30, 32) to clear a substance from brain parenchyma of the subject into at least one region of the brain selected from the group consisting of: a subarachnoid space of the brain and dural sinuses of the brain. Other embodiments are also described.

2. 发明申请

WO2018122834A1 ACCOMMODATIVE INTRAOCULAR LENS 审中-公开
公开(公告)号：WO2018122834A1
公开(公告)日：2018-07-05
申请号：PCT/IL2017/051317
申请日：2017-12-05
申请人： RAINBOW MEDICAL LTD.
发明人： SOHN, Zev , GROSS, Yossi
IPC分类号： A61F2/16
摘要： An accommodating intraocular lens implant (10) is provided that is shaped so as to be assemblable into an assembled state in situ in a capsular bag of a human eye, and includes an anterior floating lens unit (24), which comprises an anterior lens (26); a posterior lens unit (50), which comprises a posterior lens (52); an anterior rim (44); levers (30), arranged to move the anterior floating lens unit (24) toward and away from the anterior rim (44), in an anterior-posterior direction; and a circumferential rim (48), which is attached to the levers (30). The lens implant (10) is arranged such that in the assemble state: elastic potential energy is stored in the lens implant (10) as a result of deformation of the lens implant (10) during a transition from a fully- accommodated state to a fully- unaccommodated state, and at least 50% of the elastic potential energy stored in the lens implant (10) as the result of the deformation is stored in the circumferential rim (48).

3. 发明申请

WO2011083491A2 ALVEOLAR RIDGE AUGMENTATION 审中-公开
标题翻译： ALVEOLAR RIDGE增强
公开(公告)号：WO2011083491A2
公开(公告)日：2011-07-14
申请号：PCT/IN2010/000975
申请日：2010-11-22
申请人： RAINBOW MEDICAL LTD. , BETTER, Hadar , FOSTICK, Gideon , GROSS, Yossi
发明人： BETTER, Hadar , FOSTICK, Gideon , GROSS, Yossi
IPC分类号： A61C17/16
CPC分类号： A61C8/0006 , A61B17/24 , A61B17/32 , A61B17/3209 , A61B18/14 , A61B18/20 , A61B2017/0647 , A61B2017/0648 , A61B2017/3225 , A61B2018/144 , A61B2018/1467 , A61N7/02
摘要： Apparatus is provided for use with a gingival periosteum (230) lining a bone. The apparatus comprises a periosteal mesher (200), which comprises a mesher surface (210), and a plurality of cutting elements (212) distributed over the mesher surface (210), which are configured to cut the gingival periosteum (230) to increase flexibility thereof. Other embodiments are also described.
摘要翻译：提供了用于衬有骨的齿龈骨膜（230）的装置。该设备包括具有网格表面（210）的骨膜网格（200）和分布在网格表面（210）上的多个切割元件（212），其被配置为切割牙龈骨膜（230）以增加其灵活性。还描述了其他实施例。

4. 发明申请

WO2009095920A2 INTRA-AORTIC ELECTRICAL COUNTERPULSATION 审中-公开
标题翻译：内部电动计数器
公开(公告)号：WO2009095920A2
公开(公告)日：2009-08-06
申请号：PCT/IL2009/000117
申请日：2009-01-29
申请人： RAINBOW MEDICAL LTD. , GROSS, Yossi , DAGAN, Amir
发明人： GROSS, Yossi , DAGAN, Amir
IPC分类号： A61N1/05
CPC分类号： A61N1/36114 , A61N1/05 , A61N1/36564 , A61N1/3962
摘要： In some embodiments of the present invention, apparatus is provided, including a sensing electrode (22) configured to be implanted at a non-cardiac site in a vicinity of an aorta (24) of a subject and to detect an electrical parameter of the aorta, and a control unit (26) configured to receive the detected parameter and to generate an output in response to the detected parameter. Additional embodiments are also described.
摘要翻译：在本发明的一些实施例中，提供了一种设备，包括被配置为植入在受试者的主动脉（24）附近的非心脏部位并且检测主动脉的电参数的感测电极（22），以及控制单元（26），被配置为接收检测到的参数并且响应于检测到的参数而生成输出。还描述了另外的实施例。

5. 发明申请

WO2015170256A2 PERICARDIAL ACCESS DEVICE 审中-公开
标题翻译： PERICARDIAL访问设备
公开(公告)号：WO2015170256A2
公开(公告)日：2015-11-12
申请号：PCT/IB2015/053280
申请日：2015-05-05
申请人： RAINBOW MEDICAL LTD
发明人： GROSS, Yossi , KARDOSH, Michael , KISHON, Amir , SADAN, Ido , YALOM, Jonathan , SOHN, Zev , GINO, Omri , YANOVITZ, Leonid , RIMER-COHEN, Ofir
IPC分类号： A61B17/34
CPC分类号： A61B17/3423 , A61B1/00082 , A61B1/00087 , A61B1/00089 , A61B1/00094 , A61B1/00135 , A61B1/00137 , A61B1/00179 , A61B1/00183 , A61B1/018 , A61B1/06 , A61B1/0623 , A61B1/0669 , A61B1/0676 , A61B1/0684 , A61B1/07 , A61B1/126 , A61B1/313 , A61B17/12013 , A61B17/135 , A61B17/3403 , A61B17/3468 , A61B17/3478 , A61B2017/00243 , A61B2017/00247 , A61B2017/003 , A61B2017/00867 , A61B2017/00907 , A61B2017/0092 , A61B2017/12004 , A61B2017/306 , A61B2017/320044 , A61B2017/320048 , A61B2017/3419 , A61B2017/3425 , A61B2017/3445 , A61B2017/3456 , A61B2017/3484 , A61B2017/3486 , A61B2017/3488 , A61B2090/034
摘要： Apparatus (120) is provided comprising: a longitudinal guide member (220) (a) comprising a blunt distal end (160) having an outer surface (164) at least part of which is transparent, (b) configured to be advanced distally toward a heart of a subject, and (c) shaped to define an at least partially distally-facing and side-facing suction port (660) at a distal portion (662) of the longitudinal guide member (220). The apparatus is configured to facilitate drawing a portion of a pericardium of the heart through the suction port and into the longitudinal guide member. The apparatus additionally comprises a puncturing element (50) configured to puncture the portion of the pericardium while the portion of the pericardium is in the longitudinal guide member. Other applications are also described.
摘要翻译：设备（120）包括：纵向引导件（220）（a），包括钝的远端（160），其具有至少部分透明的外表面（164），（b）被配置为朝向主体的心脏，以及（c）成形为在所述纵向引导构件（220）的远端部分（662）处限定至少部分地朝向远端并面向侧面的吸入口（660）。该装置被配置为便于通过吸入口并进入纵向引导构件来拉伸心脏心包的一部分。该装置还包括穿刺元件（50），其构造成在心包的部分位于纵向引导构件中时刺穿心包的部分。还描述了其它应用。

6. 发明申请

WO2013121424A2 REFLECTANCE-FACILITATED ULTRASOUND TREATMENT AND MONITORING 审中-公开
标题翻译：反射辅助超声治疗和监测
公开(公告)号：WO2013121424A2
公开(公告)日：2013-08-22
申请号：PCT/IL2013/050134
申请日：2013-02-13
申请人： RAINBOW MEDICAL LTD.
发明人： KARDOSH, Michael , KISHON, Amir , RABBAN, Navot , MAGNAZI, Gilad , GROSS, Yossi
IPC分类号： A61N7/02
CPC分类号： A61N7/022 , A61B5/0084 , A61B5/01 , A61B5/0422 , A61B5/065 , A61B5/1076 , A61B5/6853 , A61B5/7285 , A61B8/12 , A61B90/361 , A61B2018/0022 , A61B2018/00351 , A61B2018/00357 , A61B2018/00375 , A61B2018/00577 , A61B2090/378 , A61B2505/05 , A61M25/04 , A61M25/10 , A61M2025/1047 , A61N1/0563 , A61N1/0587 , A61N2007/0069
摘要： Apparatus for ablating tissue of a subject is provided. The apparatus includes a reflection-facilitation element (20) having an inflatable element (22), which is placed at a first side of the tissue of the subject; and an introducer (24), coupled to the inflatable element which delivers a fluid to the first side of the tissue, such that a portion of the fluid is disposed within the inflatable element, and another portion of the fluid is disposed outside of the inflatable element. The apparatus also includes an ultrasound tool (90), having at least one ultrasound transducer (92), which is placed at a second side of the tissue, and applies ultrasound energy such that at least a portion of the applied energy is reflected by the fluid. Other applications are also described.
摘要翻译：提供了用于消融受试者的组织的装置。该装置包括具有可膨胀元件（22）的反射促进元件（20），该可充气元件放置在被检体的组织的第一侧; 以及导引器（24），其连接到所述可充气元件，所述引导器将流体输送到所述组织的第一侧，使得所述流体的一部分设置在所述可膨胀元件内，并且所述流体的另一部分设置在所述可充气元件的外部元件。所述装置还包括具有至少一个超声换能器（92）的超声波工具（90），所述超声波换能器放置在所述组织的第二侧，并且施加超声波能量，使得所施加的能量的至少一部分被流体。还描述了其它应用。

7. 发明申请

WO2011083456A1 ALVEOLAR RIDGE AUGMENTATION 审中-公开
标题翻译：爱尔兰骑士队
公开(公告)号：WO2011083456A1
公开(公告)日：2011-07-14
申请号：PCT/IL2010/000975
申请日：2010-11-22
申请人： RAINBOW MEDICAL LTD. , BETTER, Hadar , FOSTICK, Gideon , GROSS, Yossi
发明人： BETTER, Hadar , FOSTICK, Gideon , GROSS, Yossi
IPC分类号： A61B17/32
CPC分类号： A61C8/0006 , A61B17/24 , A61B17/32 , A61B17/3209 , A61B18/14 , A61B18/20 , A61B2017/0647 , A61B2017/0648 , A61B2017/3225 , A61B2018/144 , A61B2018/1467 , A61N7/02
摘要： Apparatus is provided for use with a gingival periosteum (230) lining a bone. The apparatus comprises a periosteal mesher (200), which comprises a mesher surface (210), and a plurality of cutting elements (212) distributed over the mesher surface (210), which are configured to cut the gingival periosteum (230) to increase flexibility thereof. Other embodiments are also described.
摘要翻译：设置用于与骨衬里的牙龈骨膜（230）一起使用。该装置包括骨膜网（200），其包括网状物表面（210）和分布在所述网状物表面（210）上的多个切割元件（212），其被配置为切割牙龈骨（230）以增加灵活性。还描述了其它实施例。

8. 发明申请

WO2009095918A2 PERISTALTIC PUMP FOR TREATMENT OF ERECTILE DYSFUNCTION 审中-公开
标题翻译：用于治疗溃疡性功能障碍的尿液泵
公开(公告)号：WO2009095918A2
公开(公告)日：2009-08-06
申请号：PCT/IL2009/000115
申请日：2009-01-29
申请人： RAINBOW MEDICAL LTD. , GROSS, Yossi
发明人： GROSS, Yossi
IPC分类号： A61F5/00
CPC分类号： A61F2/26 , A61N1/0408 , A61N1/0476 , A61N1/0492 , A61N1/05 , A61N1/321 , A61N1/36007
摘要： In some embodiments of the present invention, apparatus is provided for treating erectile dysfunction of a subject. The apparatus includes one or more electrodes (22) configured to be coupled to a vicinity of a blood vessel (50) that carries blood into or out of a penis (52) of the subject, and a control unit (24) configured to facilitate erection of the penis by peristaltically pumping blood in the blood vessel by stimulating nitric oxide (NO) production in the vicinity, by driving the electrodes to drive a current into the vicinity. Additional embodiments are also described.
摘要翻译：在本发明的一些实施方案中，提供了用于治疗受试者勃起功能障碍的装置。该装置包括一个或多个电极（22），其被配置为耦合到携带血液进入或离开受试者的阴茎（52）的血管（50）附近;以及控制单元（24），其被配置为便于通过驱动电极驱动电流进入附近，通过刺激附近的一氧化氮（NO）生成，通过蠕动地抽血血液来竖立阴茎。还描述了另外的实施例。

9. 发明申请

WO2017208230A1 ACCOMMODATIVE INTRAOCULAR LENS 审中-公开
标题翻译：适应性人工晶状体
公开(公告)号：WO2017208230A1
公开(公告)日：2017-12-07
申请号：PCT/IL2017/050594
申请日：2017-05-29
申请人： RAINBOW MEDICAL LTD.
发明人： SOHN, Zev , GROSS, Yossi
IPC分类号： A61F2/16
摘要： An accommodating intraocular lens implant (10) includes an anterior floating lens unit (24), which includes an anterior lens (26); a posterior lens unit (50), which includes a posterior lens (52); an anterior rim complex (44); levers (30); and a ring (100). The levers (30) are (a) (i) in jointed connection with the anterior floating lens unit (24) at respective first longitudinal sites (60) along the levers (30), (ii) in pivotable connection with the anterior rim complex (44) at respective second longitudinal sites (62) along the levers (30), and (iii) in pivotable contact with the posterior lens unit (50) at respective third longitudinal sites (64) along the levers (30), and (b) arranged to move the anterior floating lens unit (24) toward and away from the anterior rim complex (44), in an anterior- posterior direction. The ring (100) has a diameter greater than that of the anterior lens (26), and is connected to the levers (30). The lens implant (10) is configured such that the ring (100) deforms during a transition of the lens implant (10) between a fully- accommodated state and a fully-unaccommodated state.
摘要翻译：可调节的人工晶状体植入物（10）包括前部浮动透镜单元（24），其包括前部透镜（26）; 后透镜单元（50），其包括后透镜（52）;后透镜单元前缘复合体（44）; 杠杆（30）; 和一个环（100）。杠杆（30）是（a）（i）在沿杠杆（30）的相应第一纵向位置（60）处与前部浮动透镜单元（24）接合连接，（ii）与前部边缘复合体（30）处的相应的第二纵向位置（62）处，以及（iii）在沿着所述杠杆（30）的相应的第三纵向位置（64）处与所述后透镜单元（50）枢转接触，以及 b）布置成沿前 - 后方向将前部浮动透镜单元（24）朝向和远离前部边缘复合体（44）移动。环（100）的直径大于前透镜（26）的直径，并连接到杠杆（30）。所述晶状体植入物（10）被配置为使得所述环（100）在所述晶状体植入物（10）在完全容纳状态和完全未适应状态之间转变期间变形。

10. 发明申请

WO2015170281A1 CONTROLLED TISSUE ABLATION TECHNIQUES 审中-公开
标题翻译：控制组织抽搐技术
公开(公告)号：WO2015170281A1
公开(公告)日：2015-11-12
申请号：PCT/IB2015/053350
申请日：2015-05-07
申请人： RAINBOW MEDICAL LTD
发明人： GROSS, Yossi , MEIRY, Gideon , ZADOK, Yehuda
IPC分类号： A61B18/14 , A61N1/36
CPC分类号： A61B18/1492 , A61B5/021 , A61B5/4836 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00642 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00839 , A61B2018/00863 , A61N1/0551 , A61N1/36007 , A61N1/36017 , A61N1/36117 , A61N1/36135 , G02B6/1228 , G02B6/136 , G02B6/305 , G02B2006/12061
摘要： Apparatus and methods are described, including a method for use with tissue of a renal nerve (770) passing longitudinally within a wall of a renal artery (8) of a subject. Using one or more stimulating electrodes (850a, 850b) disposed within the renal artery, the tissue is stimulated by passing a stimulating current through the wall of the renal 5 artery. Using a sensor (26), a rate of change of blood pressure of the subject is sensed, following the start of the stimulation of the tissue. In response to the rate of change, it is decided whether to ablate the tissue, and in response to deciding to ablate the tissue, the tissue is ablated. Other applications are also described.
摘要翻译：描述了装置和方法，包括与受试者的肾动脉（8）的壁内纵向通过的肾神经组织（770）一起使用的方法。使用设置在肾动脉内的一个或多个刺激电极（850a，850b），通过使刺激电流通过肾脏5动脉的壁来刺激组织。使用传感器（26），在组织的刺激开始之后，感测对象的血压变化率。响应于变化率，决定是否消融组织，并且响应于决定烧蚀组织，消融组织。还描述了其它应用。

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