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    • 1. 发明申请
    • ELECTRICAL SUBSTANCE CLEARANCE FROM THE BRAIN
    • 电气物质从大脑中清除
    • WO2017072769A1
    • 2017-05-04
    • PCT/IL2016/051161
    • 2016-10-27
    • RAINBOW MEDICAL LTD.
    • FOSTICK, GideonGROSS, YossiTENDLER, Alex
    • A61N1/32A61N1/30
    • A61N1/36082A61N1/0529A61N1/0534A61N1/306A61N1/327
    • A system (20) is provided that includes a parenchymal electrode (30), configured to be implanted in brain parenchyma (50) of a subject identified as at risk of or suffering from a disease; and a cerebrospinal fluid (CSF) electrode (32), configured to be implanted in a CSF-filled space of a brain (52) of the subject, the CSF-filled space selected from the group consisting of: a ventricular system (54) and a subarachnoid space (144). Control circuitry (34) is configured to drive the parenchymal electrode (30) and the CSF electrode (32) to clear a substance from the brain parenchyma (50) into the CSF-filled space of the brain (52). Other embodiments are also described.
    • 提供了包括实质电极(30)的系统(20),所述实质电极(30)被配置为植入被鉴定为处于患病或患有疾病的受试者的脑实质(50)中; 和脑脊液(CSF)电极(32),所述脑脊液(CSF)电极被配置为植入所述受试者的大脑(52)的CSF填充空间中,所述CSF填充空间选自:心室系统(54) 和蛛网膜下腔(144)。 控制电路(34)被配置为驱动实质电极(30)和CSF电极(32)以将来自脑实质(50)的物质从脑部(52)的脑脊液填充空间中清除。 还描述了其他实施例。