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1. 发明申请

WO2022120423A1 PEPTIDES AND USES THEREOF 审中-公开
公开(公告)号：WO2022120423A1
公开(公告)日：2022-06-16
申请号：PCT/AU2021/051465
申请日：2021-12-08
申请人： JAMES COOK UNIVERSITY [AU]/[AU] , THE UNIVERSITY OF QUEENSLAND [AU]/[AU]
发明人： COBOS, Claudia , DALY, Norelle , LOUKAS, Alex , BANSAL, Paramjit , TOTH, Istvan , SKWARCZYNSKI, Mariusz
IPC分类号： C07K14/435 , A61K35/62 , A61K38/00 , A61K38/08 , A61K38/10 , A61P1/00 , A61P11/06 , A61P29/00 , A61P37/06
摘要： The present invention relates to a peptide for treating an inflammatory or autoimmune condition, pharmaceutical compositions comprising same, and methods of use comprising same.

2. 发明申请

WO2020113279A1 NOVEL COMPOSITION 审中-公开
公开(公告)号：WO2020113279A1
公开(公告)日：2020-06-11
申请号：PCT/AU2019/051335
申请日：2019-12-06
申请人： JAMES COOK UNIVERSITY , PACIFIC BIOTECHNOLOGIES LTD
发明人： DE NYS, Rocky , MAGNUSSON, Marie, Elisabeth
IPC分类号： A61K36/04 , A23K50/10 , A23K10/10 , A61P1/14
摘要： The field of the invention relates to processes for preparing Asparagopsis oil compositions, comprising extracting at least one bioactive from a biomass of Asparagopsis into an oil to form the compositions. These compositions are suitable for reducing total gas production and/or methane production in a ruminant or pseudo-ruminant animal.

3. 发明申请

WO2015149121A1 METHOD FOR THE CULTIVATION AND PRODUCTION OF MACROALGAE 审中-公开
标题翻译：用于生产和生产大肠杆菌的方法
公开(公告)号：WO2015149121A1
公开(公告)日：2015-10-08
申请号：PCT/AU2015/050112
申请日：2015-03-17
申请人： JAMES COOK UNIVERSITY , MBD ENERGY LIMITED
发明人： CARL, Christina , PAUL, Nicholas , DE NYS, Rocky
IPC分类号： A01G33/00
CPC分类号： A01G33/00 , Y02A40/241
摘要： A method is provided for the cultivation and/or production of green macroalgae, such as Ulva spp . The green macroalgae are exposed to a temperature shock, such as a cold shock or a heat shock to induce reproduction, then maintained under suitable conditions. The method may further comprise fragmenting the temperature shocked green macroalgae. Green macroalgae may be produced according to the invention, such as for the production of biomass, wastewater treatment, bioremediation, human consumption, animal feed, and/or feedstock for the supply of pharmaceuticals, nutraceuticals, cosmeceuticals and/or biofuels. The method may be performed within a marine or brackish water environment, such as an aquaculture farm.
摘要翻译：提供了一种用于培养和/或生产诸如Ulva spp的绿色大型藻类的方法。绿色的大型海藻暴露于温度冲击，例如寒冷的休克或热休克，以诱导繁殖，然后在合适的条件下保持。该方法还可以包括破碎温度震惊的绿色大型藻类。可以根据本发明生产绿色大型藻类，例如用于生产生物质，废水处理，生物修复，人类消费，动物饲料和/或用于供应药物，营养保健品，药用植物和/或生物燃料的原料。该方法可以在海水或微咸水环境中进行，例如水产养殖场。

4. 发明申请

WO2015027274A1 COATING FOR AN IMPLANTABLE BIOMATERIAL, IMPLANTABLE BIOMATERIAL AND METHOD OF MAKING THE COATING AND BIOMATERIAL 审中-公开
标题翻译：用于可植入生物材料的涂层，可植入的生物材料以及制造涂层和生物材料的方法
公开(公告)号：WO2015027274A1
公开(公告)日：2015-03-05
申请号：PCT/AU2014/000845
申请日：2014-08-27
申请人： JAMES COOK UNIVERSITY
发明人： JACOB, Mohan Vadakkedam , BAZAKA, Kateryna
IPC分类号： C09D193/04 , A61L27/34 , A61L27/58 , B05D3/14 , C23C4/04
CPC分类号： C23C16/52 , A61L31/022 , A61L31/048 , A61L31/10 , A61L2420/02 , B05D1/62 , B05D2202/00 , C09D191/00 , C23C16/505 , C08L9/10
摘要： The invention provides a coating for a biomaterial, the coating comprising monomeric units comprising a terpene or terpene analogue or derivative polymerised by plasma polymerisation. The invention also provides a method of coating a biomaterial in which monomeric units comprising a terpene or terpene analogue or derivative are polymerised with plasma polymerisation to form a polymer and the polymer is deposited as a coating on a biomaterial substrate. Also provided is a biomaterial comprising a substrate and the polymeric coating along with a method of making a biomaterial comprising polymerising terpene or terpene analogue or derivative monomeric units and depositing the polymer as a coating on a. biomaterial substrate. The invention also provides a method of reducing the degradation rate of a biomaterial.
摘要翻译：本发明提供了一种用于生物材料的涂层，该涂层包含包含萜烯或萜烯类似物的单体单元或通过等离子体聚合聚合的衍生物。本发明还提供一种涂覆生物材料的方法，其中包含萜烯或萜烯类似物或衍生物的单体单元与等离子体聚合聚合以形成聚合物，并且聚合物作为涂层沉积在生物材料基材上。还提供了包含基底和聚合物涂层的生物材料以及制备生物材料的方法，所述生物材料包括聚合萜烯或萜烯类似物或衍生物单体单元并将聚合物作为涂层沉积在其上。生物材料基材。本发明还提供降低生物材料的降解速率的方法。

5. 发明申请

WO2008067609A1 METHOD AND COMPOSITION FOR REDUCING REPERFUSION INJURY 审中-公开
标题翻译：减少再灌注损伤的方法和组合物
公开(公告)号：WO2008067609A1
公开(公告)日：2008-06-12
申请号：PCT/AU2007/001885
申请日：2007-12-07
申请人： ADELAIDE RESEARCH & INNOVATION PTY LTD , JAMES COOK UNIVERSITY , NIMMO, Alan, John , WHITFIELD, Karen, Margaret , TURNER, Renée, Jade , VINK, Robert
发明人： NIMMO, Alan, John , WHITFIELD, Karen, Margaret , TURNER, Renée, Jade , VINK, Robert
IPC分类号： A61K31/405 , A61K38/43 , A61P7/02 , A61K31/00 , A61K38/49 , A61P9/10
CPC分类号： A61K31/405 , A61K31/00 , A61K31/451 , A61K38/04 , A61K38/49 , A61K45/06 , A61K2300/00
摘要： The present invention relates to a method of preventing and/or reducing reperfusion injury to a tissue, organ, or organ system in a subject. The method includes administering to the subject an effective amount of a substance P receptor antagonist.
摘要翻译：本发明涉及一种预防和/或减少对受试者的组织，器官或器官系统的再灌注损伤的方法。该方法包括向受试者施用有效量的P物质受体拮抗剂。

6. 发明申请

WO2006021031A1 PROCESS FOR COPPER ELECTROWINNING AND ELECTROREFINING 审中-公开
标题翻译：铜电镀和电镀工艺
公开(公告)号：WO2006021031A1
公开(公告)日：2006-03-02
申请号：PCT/AU2005/001262
申请日：2005-08-23
申请人： JAMES COOK UNIVERSITY , FABIAN, Cesimiro, Paulino , LANCASTER, Thomas, William
发明人： FABIAN, Cesimiro, Paulino , LANCASTER, Thomas, William
IPC分类号： C22B15/00
CPC分类号： C22B15/0084 , C22B3/0097 , C22B15/0069 , C25C1/12 , Y02P10/234 , Y02P10/236
摘要： A method of electrowinning or electrorefining copper from a copper electrolyte solution which contains chloride ions, the method comprising the steps of: (a) forming a polyacrylamide solution by dissolving polyacrylamide, having a molecular weight range of 5,000 to 20,000,000 Daltons, in an acidic medium and under conditions to form a polyacrylamide block copolymer having blocks of carboxyl groups dispersed along the polymer backbone; (b) introducing the polyacrylamide solution into an electrolytic cell containing the copper electrolyte solution at a polyacrylamide concentration of 0.01-10 mg/L; and (c) electroplating copper from the copper electrolyte solution to form a copper cathode.
摘要翻译：一种从包含氯离子的铜电解液中电解或电解铜的方法，所述方法包括以下步骤：（a）通过将分子量范围为5,000至20,000,000道尔顿的聚丙烯酰胺溶解在酸性介质中形成聚丙烯酰胺溶液并在条件下形成具有沿聚合物主链分散的羧基嵌段的聚丙烯酰胺嵌段共聚物; （b）以聚丙烯酰胺浓度为0.01〜10mg / L，将聚丙烯酰胺溶液引入含有铜电解质溶液的电解槽中; 和（c）从铜电解液中电镀铜以形成铜阴极。

7. 发明申请

WO1995032605A1 PRINTED CIRCUIT BOARD SOCKET 审中-公开
标题翻译：打印电路板插座
公开(公告)号：WO1995032605A1
公开(公告)日：1995-11-30
申请号：PCT/AU1995000301
申请日：1995-05-25
申请人： JAMES COOK UNIVERSITY OF NORTH QUEENSLAND , SUEHRCKE, Harry , LOVISA, Noel, Wilhelmus
发明人： JAMES COOK UNIVERSITY OF NORTH QUEENSLAND
IPC分类号： H05K01/16
CPC分类号： H05K1/119 , H05K3/306 , H05K3/326 , H05K2201/09063 , H05K2201/09081 , H05K2201/10053 , H05K2201/1059
摘要： An electrical socket is formed in a printed circuit board (PCB) using standard automated PCB production techniques. The socket (20) comprises a respective three legged slotted aperture (22) for each pin (11) of a male plug. The slotted aperture (22) defines two cantilevered portions (23) which receive a respective pin (11) in a slot defined therebetween. The slot is of slightly narrower width than the corresponding pin (11), but the cantilevered portions (23) are resiliently movable to enable the slot to receive and frictionally retain the pin therein. Plated contact surfaces are formed on either side of the slot to make physical and electrical contact with the pin. A modified socket (40) includes an integrally formed isolation switch. The cantilevered portions (41) extend beyond the point where the pin (11) is inserted therebetween. The distal ends of the cantilevered portions (41) are provided with respective contact surfaces (43, 44) which are normally spaced apart, but come into contact to close the switch when the cantilevered portions (41) are splayed apart by the insertion of a pin therebetween. Alternatively, contacts (32) on the cantilevered portions may be arranged to come into contact with corresponding contacts (33) on the circuit board.
摘要翻译：使用标准的自动PCB生产技术在印刷电路板（PCB）中形成电插座。插座（20）包括用于公插头的每个销（11）的相应的三个有腿的开口孔（22）。开槽孔（22）限定两个悬臂部分（23），它们在限定在其间的槽中容纳相应的销钉（11）。狭槽的宽度比对应的销（11）略窄，但是悬臂部分（23）是可弹性移动的，以使缝隙能够容纳和摩擦地将销保持在其中。电镀的接触表面形成在槽的任一侧，以与销物理和电接触。改进的插座（40）包括一体形成的隔离开关。悬臂部分（41）延伸超过销（11）插入其间的点。悬臂部分（41）的远端设有各自的接触表面（43,44），其通常间隔开，但是当悬臂部分（41）通过插入在它们之间。或者，悬臂部分上的触点（32）可以布置成与电路板上的对应触点（33）接触。

8. 发明申请

WO2022170394A1 RECOMBINANT STRAINS OF MYCOBACTERIUM BOVIS BCG 审中-公开
公开(公告)号：WO2022170394A1
公开(公告)日：2022-08-18
申请号：PCT/AU2022/050086
申请日：2022-02-10
申请人： JAMES COOK UNIVERSITY , KRISHNAMOORTHY, Gopinath , HUSAIN, Aliabbas A.
发明人： KUPZ, Andreas
IPC分类号： A61K39/04 , A61P31/06 , C07K14/35 , C12N1/20 , C12N1/36 , C12N15/74 , C12R1/32
摘要： The present invention provides recombinant strains of M. bovis BCG comprising a heterologous nucleic acid encoding a fusion protein, wherein the fusion protein comprises or consists of: a) a polypeptide that is at least about 80% identical to an ESAT-6 protein and b) a secretion peptide for enabling secretion of the polypeptide via an ESX-5 secretion system of M. bovis BCG.

9. 发明申请

WO2012135902A1 PROTEASE ACTIVITY ASSAY 审中-公开
标题翻译： PROTEASE活动测定
公开(公告)号：WO2012135902A1
公开(公告)日：2012-10-11
申请号：PCT/AU2012/000343
申请日：2012-04-04
申请人： JAMES COOK UNIVERSITY , SCHAEFFER, Patrick
发明人： SCHAEFFER, Patrick
IPC分类号： G01N33/52 , C12N15/62 , G01N33/58
CPC分类号： C12N15/62 , C07K2319/50 , C07K2319/60 , C12Q1/37 , G01N33/542 , G01N33/582
摘要： The present invention discloses methods for assessing protease activity and fusion protein substrates suitable for use in such methods. The fusion protein substrates comprise a stable fluorescent protein, a linker and an unstable non- fluorescent protein, wherein the linker comprises a protease recognition sequence recognised by the protease to be quantified. More particularly, this invention relates to improved assays for quantifying protease activity.
摘要翻译：本发明公开了适用于这些方法的蛋白酶活性评估方法和融合蛋白底物。所述融合蛋白底物包含稳定的荧光蛋白，接头和不稳定的非荧光蛋白，其中所述连接体包含待定量的蛋白酶识别的蛋白酶识别序列。更具体地，本发明涉及用于定量蛋白酶活性的改进的测定法。

10. 发明申请

WO2012092647A1 A METHOD AND SYSTEM FOR LINEARISING A RADIO FREQUENCY TRANSMITTER 审中-公开
标题翻译：用于线性化无线电频率发射机的方法和系统
公开(公告)号：WO2012092647A1
公开(公告)日：2012-07-12
申请号：PCT/AU2011/001690
申请日：2011-12-23
申请人： JAMES COOK UNIVERSITY , LAKI, Bradley Dean , KIKKERT, Cornelis Jan
发明人： LAKI, Bradley Dean , KIKKERT, Cornelis Jan
IPC分类号： H04L27/00
CPC分类号： H04L27/368 , H04B1/62 , H04B2201/70706 , H04L27/2626
摘要： A method for linearising a multi-carrier radio frequency transmitter or a multi-user CDMA radio frequency transmitter enables improved linearisation. The method includes measuring a function of out-of-band signal power in the frequency domain at an output of the radio frequency transmitter. A digital base-band pre-distortion, performed by a digital base-band pre-distortion network, is then applied to the radio frequency transmitter according to the measured function of the out-of-band signal power.
摘要翻译：用于线性化多载波射频发射机或多用户CDMA射频发射机的方法使得能够改进线性化。该方法包括在射频发射机的输出处测量频域中的带外信号功率的功能。然后，由数字基带预失真网络执行的数字基带预失真根据测量的带外信号功率的功能被施加到射频发射机。

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