基本信息:
- 专利标题： RECOMBINANT STRAINS OF MYCOBACTERIUM BOVIS BCG
- 申请号：PCT/AU2022/050086 申请日：2022-02-10
- 公开(公告)号：WO2022170394A1 公开(公告)日：2022-08-18
- 发明人： KUPZ, Andreas
- 申请人： JAMES COOK UNIVERSITY , KRISHNAMOORTHY, Gopinath , HUSAIN, Aliabbas A.
- 申请人地址： 1 James Cook Drive; c/- 1 James Cook Drive; c/- 1 James Cook Drive
- 专利权人： JAMES COOK UNIVERSITY,KRISHNAMOORTHY, Gopinath,HUSAIN, Aliabbas A.
- 当前专利权人： JAMES COOK UNIVERSITY,KRISHNAMOORTHY, Gopinath,HUSAIN, Aliabbas A.
- 当前专利权人地址： 1 James Cook Drive; c/- 1 James Cook Drive; c/- 1 James Cook Drive
- 代理机构： FPA PATENT ATTORNEYS PTY LTD
- 优先权： AU2021900320 2021-02-10
- 主分类号： A61K39/04
- IPC分类号： A61K39/04 ; A61P31/06 ; C07K14/35 ; C12N1/20 ; C12N1/36 ; C12N15/74 ; C12R1/32
摘要：
The present invention provides recombinant strains of M. bovis BCG comprising a heterologous nucleic acid encoding a fusion protein, wherein the fusion protein comprises or consists of: a) a polypeptide that is at least about 80% identical to an ESAT-6 protein and b) a secretion peptide for enabling secretion of the polypeptide via an ESX-5 secretion system of M. bovis BCG.
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K39/00 | 含有抗原或抗体的医药配制品 |
| --------A61K39/002 | .原生动物抗原 |
| ----------A61K39/04 | ..分枝杆菌属如结核杆菌 |