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1. 发明申请

WO2011084387A2 METHODS AND KITS FOR DETECTING RISK FACTORS FOR DEVELOPMENT OF JAW OSTEONECROSIS AND METHODS OF TREATMENT THEREOF 审中-公开
标题翻译：检测风险因素的方法和检测手段，用于发展AW AW AW AW R IS IS IS IS OF OF OF OF OF OF OF OF OF OF
公开(公告)号：WO2011084387A2
公开(公告)日：2011-07-14
申请号：PCT/US2010/060139
申请日：2010-12-13
申请人： UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. , KATZ, Joseph , LANGAEE, Taimour, Y.
发明人： KATZ, Joseph , LANGAEE, Taimour, Y.
IPC分类号： C12Q1/68 , C12N15/12
CPC分类号： C12Q1/6883 , C12Q2600/156 , C12Q2600/172
摘要： Methods of and kits for determining the pharmacogenetic, pharmacokinetic and cellular basis of bisphosphonate-induced osteonecrosis of the jaw (BONJ) involve associating particular proteins and particular single nucleotide polymorphisms with a risk for developing BONJ after receiving bisphosphonate treatment. Methods and kits for identifying the genetic basis for a patient's predisposition to BONJ, and methods of identifying patients who are prone to develop BONJ following bisphosphonate administration provide for the development of a tool for physicians to prescribe treatment protocols for BONJ patients based on the patients' genomes ("personal/tailored medicine"). A haplotype tagging SNP approach was used to analyze candidate genes involved in bone absorption and destruction and to examine the influence of genetic variants on the susceptibility of BONJ. Bone biomarkers of BONJ were examined using molecular cell techniques. The methods described herein can be used to identify differences in how patients are genetically predisposed to BONJ as well as genetic differences amongst patients that account for differences in how these patients clear bisphosphonate s from their systems. Determining such genetic differences provides for improved monitoring of the drugs used to treat BONJ, improved prevention of BONJ, and optimized treatment for patients having BONJ or predisposed to BONJ.
摘要翻译：用于测定双膦酸盐诱导的颌骨骨坏死（BONJ）的药物遗传学，药代动力学和细胞学基础的方法和试剂盒涉及将具体的蛋白质和具体的单核苷酸多态性与接受双膦酸盐治疗后发生BONJ的风险相关联。用于鉴定患者对BONJ倾向的遗传基础的方法和试剂盒，以及鉴定双膦酸盐给药后容易发展BONJ的患者的方法，为医师开发出一种工具，用于根据患者的BONJ开发BONJ患者的治疗方案，基因组（“个人/定制药”）。使用单倍型标记SNP方法分析参与骨吸收和破坏的候选基因，并检查遗传变异对BONJ敏感性的影响。使用分子细胞技术检查BONJ的骨生物标志物。本文描述的方法可以用于鉴定患者如何遗传易感BONJ的差异以及患者之间的遗传差异，这些差异表明这些患者如何从其系统中清除双膦酸盐。确定这样的遗传差异提供改进的用于治疗BONJ的药物的监测，改善BONJ的预防，以及对具有BONJ或倾向于BONJ的患者的优化治疗。

2. 发明申请

WO2010005939A1 METHODS AND KITS FOR DETECTING RISK FACTORS FOR DEVELOPMENT OF JAW OSTEONECROSIS AND METHODS OF TREATMENT THEREOF 审中-公开
标题翻译：检测风险因素的方法和检测手段，用于发展AW AW AW AW R IS IS IS IS OF OF OF OF OF OF OF OF OF OF
公开(公告)号：WO2010005939A1
公开(公告)日：2010-01-14
申请号：PCT/US2009/049767
申请日：2009-07-07
申请人： UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. , KATZ, Joseph , LANGAEE, Taimour
发明人： KATZ, Joseph , LANGAEE, Taimour
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172
摘要： Determining the pharmacogenetic, pharmacokinetic and cellular basis of bisphosphonate-induced osteonecrosis of the jaw (BONJ) via associating particular proteins and particular single nucleotide polymorphisms with a risk for developing BONJ after receiving bisphosphonate treatment. Methods and kits for identifying the genetic basis for a patient's predisposition to BONJ. A haplotype tagging SNP approach was used to analyze candidate genes involved in bone absorption and destruction and to examine the influence of genetic variants on the susceptibility of BONJ. Bone biomarkers of BONJ are disclosed. Said biomarkers provide for improved monitoring of the drugs used to treat BONJ, improved prevention of BONJ, and optimized treatment of patients having BONJ or predisposed to BONJ.
摘要翻译：通过将特定蛋白质和特定单核苷酸多态性与接受双膦酸盐治疗后发生BONJ风险相关联，确定双膦酸盐诱导的颌骨骨坏死（BONJ）的药代动力学，药代动力学和细胞学基础。用于识别患者对BONJ倾向的遗传基础的方法和试剂盒。使用单倍型标记SNP方法分析参与骨吸收和破坏的候选基因，并检查遗传变异对BONJ敏感性的影响。 BONJ的骨生物标志物被公开。所述生物标志物提供对用于治疗BONJ的药物的改进监测，改善BONJ的预防，以及对具有BONJ或易患BONJ的患者的优化治疗。

3. 发明申请

WO2008095110A2 COMPOSITIONS AND METHODS FOR DETECTING CANCERS IN A SUBJECT 审中-公开
标题翻译：用于检测受试者中癌症的组合物和方法
公开(公告)号：WO2008095110A2
公开(公告)日：2008-08-07
申请号：PCT/US2008/052673
申请日：2008-01-31
申请人： UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. , KATZ, Joseph , CHAN, Edward
发明人： KATZ, Joseph , CHAN, Edward
CPC分类号： G01N33/57407 , G01N33/57419 , G01N33/57446 , G01N33/57484 , G01N2333/47
摘要： Disclosed are compositions and methods for detecting oral and gastrointestinal cancers in a subject. Autoantigen p90 was shown to be overexpressed in oral cancer cells, and this protein, as well as its companion autoantigen p62 and antibodies directed to both proteins, can be used as markers for detecting oral digestive and other cancers in a subject at an early stage.
摘要翻译：公开了用于检测受试者的口腔和胃肠癌的组合物和方法。自体抗原p90显示在口腔癌细胞中过表达，并且该蛋白质以及其伴侣自身抗原p62和针对这两种蛋白质的抗体可用作早期检测受试者口腔消化和其它癌症的标记物。

4. 发明申请

WO2013073645A1 ELEVATOR 审中-公开
标题翻译：电梯
公开(公告)号：WO2013073645A1
公开(公告)日：2013-05-23
申请号：PCT/JP2012/079721
申请日：2012-11-09
申请人： MITSUBISHI ELECTRIC CORPORATION , SHILPIEKANDULA, Vijay , YERAZUNIS, William , BARNWELL, John C., III , BORTOFF, Scott A. , KATZ, Joseph
发明人： SHILPIEKANDULA, Vijay , YERAZUNIS, William , BARNWELL, John C., III , BORTOFF, Scott A. , KATZ, Joseph
IPC分类号： B66B7/06 , B66B11/00 , B66B11/02
CPC分类号： B66B11/008 , B66B7/06 , B66B11/02 , Y10T29/49826
摘要： An elevator including a car is arranged in a shaft. A set of compensator cables are attached to a bottom of the car and engaged with a compensator drum. A set of hoist cables are attached to a top of the car and engaged with a hoist drum to move the car vertically in the shaft, wherein the set of compensator cables and the set of hoist cables are configured to only move the car vertically.
摘要翻译：包括轿厢的电梯布置在轴上。一组补偿电缆连接到汽车的底部并与补偿鼓接合。一组起重电缆连接到汽车的顶部并与起重机滚筒相接合，使轿厢在轴上垂直移动，其中，一组补偿电缆和一组起重电缆被构造成仅使轿厢垂直移动。

5. 发明申请

WO2005067314A1 METHOD AND APPARATUS FOR CONTROLLABLY COMPENSATING FOR DISTORTIONS IN A LASER PROJECTION DISPLAY 审中-公开
标题翻译：用于控制激光投影显示中的失真的方法和装置
公开(公告)号：WO2005067314A1
公开(公告)日：2005-07-21
申请号：PCT/US2004/043188
申请日：2004-12-21
申请人： SYMBOL TECHNOLOGIES, INC. , STERN, Miklos , DVORKIS, Paul , NAMBUDIRI, Narayan , WITTENBERG, Carl , TAN, Chinh , GOLDMAN, Ron , YAVID, Dmitriy , WOOD, Frederick, F. , KATZ, Joseph
发明人： STERN, Miklos , DVORKIS, Paul , NAMBUDIRI, Narayan , WITTENBERG, Carl , TAN, Chinh , GOLDMAN, Ron , YAVID, Dmitriy , WOOD, Frederick, F. , KATZ, Joseph
IPC分类号： H04N9/31
CPC分类号： H04N9/3129 , H04N5/74 , H04N9/3185 , H04N9/3194
摘要： A method and apparatus are provided to controllably compensate for distortions in an image produced by an LPD, where the distortion arises from the shape and/or angle of the viewing surface relative to the LPD. For example, the LPD can determine the angle of the viewing surface relative to the LPD and then adjust the horizontal and vertical scan mechanisms to return the image to its original configuration, such as rectangular.
摘要翻译：提供了一种方法和装置，用于可控地补偿由LPD产生的图像中的失真，其中由相对于LPD的观察表面的形状和/或角度产生变形。例如，LPD可以确定观察表面相对于LPD的角度，然后调整水平和垂直扫描机构以将图像返回到其原始配置，例如矩形。

6. 发明申请

WO2010129576A1 TRUST-BASED PERSONALIZED OFFER PORTAL 审中-公开
标题翻译：基于信任的个性化门市
公开(公告)号：WO2010129576A1
公开(公告)日：2010-11-11
申请号：PCT/US2010/033583
申请日：2010-05-04
申请人： FACE IT CORP. , FRIED, Lance , KATZ, Joseph
发明人： FRIED, Lance , KATZ, Joseph
IPC分类号： G06Q30/00
CPC分类号： G06Q30/0251 , G06Q30/02
摘要： A portal system for secure, aggregated and centralized management of delivering various offers in accordance with specified customer preferences is contemplated. An offer configuration server permits the vendor to specify offers based on various factors such as volume, start time, expiration, and to specify the particular customer device to which the offers are delivered. Customers have associated receive settings that define the preferred frequency, nature of the offers, vendors, and demographic exposure. The offers are delivered to the customer in accordance with these settings.
摘要翻译：考虑到根据指定的客户偏好来安全，集中和集中管理提供各种报价的门户系统。提供配置服务器允许供应商基于诸如卷，开始时间，到期之类的各种因素来指定报价，并且指定要提供报价的特定客户设备。客户具有相关的接收设置，定义首选频率，优惠性质，供应商和人口统计信息。根据这些设置，这些优惠将交付给客户。

7. 发明申请

WO2006093710A2 SYSTEM AND METHOD FOR ASSET LOCATION IN WIRELESS NETWORKS 审中-公开
标题翻译：无线网络资产定位系统与方法
公开(公告)号：WO2006093710A2
公开(公告)日：2006-09-08
申请号：PCT/US2006/005978
申请日：2006-02-21
申请人： SYMBOL TECHNOLOGIES, INC. , SHARONY, Jacob , KATZ, Joseph
发明人： SHARONY, Jacob , KATZ, Joseph
IPC分类号： H04W64/00
CPC分类号： G01S5/06 , G01S5/0252 , H04W4/029 , H04W4/043 , H04W64/00
摘要： A system for tracking an asset includes wireless access points and a computing arrangement communicating with the access points to determine a location of the device as a function of first data, second data indicative of a travel time of a third signal from the device to three access points and the locations of the three access points. The first data includes one of first signal strength data and second signal strength data indicative of the strength of first and second signals transmitted, respectively, by the device and received by the three access points. The location area is an area within a predetermined reception range of the three access points. The arrangement determines the location of the device within the location area as a function of second data and a further location of each of the at least three further access points of the plurality of access points.
摘要翻译：用于跟踪资产的系统包括无线接入点和与接入点通信的计算装置，以根据第一数据确定设备的位置，第二数据指示从设备到三次接入的第三信号的行进时间点和三个接入点的位置。第一数据包括第一信号强度数据和表示由设备分别由三个接入点接收的第一和第二信号的强度的第二信号强度数据中的一个。位置区域是三个接入点的预定接收范围内的区域。该布置根据第二数据和多个接入点中的至少三个其他接入点中的每一个的另一位置来确定设备在位置区域内的位置。

8. 发明申请

WO2013032925A1 NETWORK PREDICTIVE CUSTOMER SERVICE QUEUE MANAGEMENT 审中-公开
标题翻译：网络预测客户服务队伍管理
公开(公告)号：WO2013032925A1
公开(公告)日：2013-03-07
申请号：PCT/US2012/052330
申请日：2012-08-24
申请人： FACE IT CORP. , FRIED, Lance , KATZ, Joseph , KORFIN, Rick
发明人： FRIED, Lance , KATZ, Joseph , KORFIN, Rick
IPC分类号： G06Q10/00
CPC分类号： H04M3/5231 , H04M3/42059 , H04M3/42221 , H04M3/42306 , H04M3/4283 , H04M3/5238 , H04M7/125 , H04M2207/12
摘要： A communications portal for interfacing with a carrier network, a contact center, and a user is disclosed. Telecommunications links are connected to the communications portal to receive inbound calls and place outbound calls. A gateway signaling proxy containing an application server and a reverse automation subsystem is connected to the telecommunications links to recognize and store user selections, detect answer supervision, and execute scripts as configured in the user interface.
摘要翻译：公开了一种用于与运营商网络，联络中心和用户进行接口的通信门户。电信链路连接到通信门户，以接收来电和拨出呼叫。包含应用服务器和反向自动化子系统的网关信令代理连接到电信链路，以识别和存储用户选择，检测应答监视和执行在用户界面中配置的脚本。

9. 发明申请

WO2005067310A1 A LASER PROJECTION DISPLAY 审中-公开
标题翻译：激光投影显示
公开(公告)号：WO2005067310A1
公开(公告)日：2005-07-21
申请号：PCT/US2004/042836
申请日：2004-12-21
申请人： SYMBOL TECHNOLOGIES, INC. , STERN, Miklos , DVORKIS, Paul , NAMBUDIRI, Narayan , WITTENBERG, Carl , TAN, Chinh , GOLDMAN, Ron , YAVID, Dmitriy , WOOD, Frederick, F. , KATZ, Joseph
发明人： STERN, Miklos , DVORKIS, Paul , NAMBUDIRI, Narayan , WITTENBERG, Carl , TAN, Chinh , GOLDMAN, Ron , YAVID, Dmitriy , WOOD, Frederick, F. , KATZ, Joseph
IPC分类号： H04N9/31
CPC分类号： H04N9/3129
摘要： A method and apparatus are provided for controlling the operation of a Laser Projection Display (LPD). Generally, the LPD is comprised of a laser, an optical system and a controller. The laser is adapted to emit a beam of laser light. The optical system is adapted to scan the beam of laser light on a display surface in a two-dimensional raster pattern. The controller is adapted to control the rate at which the laser beam is scanned to produce regions of varying resolution on the display surface. The controller is also adapted to present laser light onto the display surface within only selected portions of the two-dimensional raster scan pattern so that spaced apart image regions may be created.
摘要翻译：提供了一种用于控制激光投射显示器（LPD）的操作的方法和装置。通常，LPD由激光器，光学系统和控制器组成。激光器适于发射激光束。光学系统适于以二维光栅图案扫描显示表面上的激光束。控制器适于控制激光束被扫描的速率，以在显示表面上产生不同分辨率的区域。该控制器还适于在二维光栅扫描图案的所选部分内的显示表面上呈现激光，从而可以产生间隔开的图像区域。

10. 发明申请

WO2013036822A1 SOCIAL PROXY AND PROTOCOL GATEWAY 审中-公开
标题翻译：社会代表和协议网关
公开(公告)号：WO2013036822A1
公开(公告)日：2013-03-14
申请号：PCT/US2012/054245
申请日：2012-09-07
申请人： FACE IT CORP. , FRIED, Lance , KATZ, Joseph
发明人： FRIED, Lance , KATZ, Joseph
IPC分类号： H04M3/00
CPC分类号： G06Q10/10 , G06Q50/01 , G10L15/30 , H04L51/32 , H04L67/327 , H04M3/5141 , H04M3/5231 , H04M2201/39 , H04M2201/40 , H04M2201/60 , H04M2203/655
摘要： A social proxy and protocol gateway for interfacing with a carrier network, a social listening device, a social network or proprietary social feedback apparatus, and a contact center and contact center database is disclosed. A data link is connected to a carrier network to receive, author tags, attributes, and routing information requests and other routing data. Additional data links are connected to a contact center database and a social network listening device or proprietary social feedback apparatus to obtain information used in determining routing and tagging instructions. A user interface is connected to the social proxy and protocol gateway to accept configurable conditions for determining routing instructions. A text conversion function and speech conversion function is disclosed for providing media conversion for the requirements of each target enterprise contact center.
摘要翻译：公开了一种用于与运营商网络，社交监听设备，社交网络或专有社交反馈设备进行接口的社交代理和协议网关，以及联络中心和联络中心数据库。数据链路连接到运营商网络以接收，作者标签，属性和路由信息请求和其他路由数据。附加数据链路连接到联络中心数据库和社交网络监听设备或专有社会反馈设备，以获得用于确定路由和标记指令的信息。用户界面连接到社交代理和协议网关，以接受用于确定路由指令的可配置条件。公开了文本转换功能和语音转换功能，用于为每个目标企业联络中心的要求提供媒体转换。

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