会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 9. 发明申请
    • ACYLOXYALKYL CARBAMATE PRODRUGS, METHODS OF SYNTHESIS AND USE
    • 丙烯酰基碳酸酯产品,合成和使用方法
    • WO2008033572A1
    • 2008-03-20
    • PCT/US2007/020210
    • 2007-09-13
    • XENOPORT, INC.GALLOP, Mark, A.XU, FengPHAN, ThuDILIP, UshaPENG, Ge
    • GALLOP, Mark, A.XU, FengPHAN, ThuDILIP, UshaPENG, Ge
    • C07F9/30A61K31/662A61P25/00
    • C07F9/301
    • Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphinic acid and analogs thereof, methods of making acyloxyalkyl carbamate prodrugs of 3- aminopropylphosphinic acid and analogs thereof, methods of using acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphinic acid and, analogs thereof, and pharmaceutical compositions comprising acyloxyalkyl carbamate prodrugs of 3- aminopropylphosphinic acid and analogs thereof for treating diseases or disorders such as mild cognitive impairment, cognitive impairment associated with Alzheimer's disease Alzheimer's disease, depression, anxiety, and epilepsy are disclosed. Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphinic acid and analogs thereof, which are suitable for oral administration and sustained release oral dosage forms are also disclosed.
    • 3-氨基丙基次膦酸的氨基甲酸烷基酯氨基甲酸酯前药及其类似物,制备3-氨基丙基次膦酸及其类似物的酰氨基烷基氨基甲酸酯前药的方法,使用3-氨基丙基次膦酸的酰氨基烷基氨基甲酸酯前药及其类似物,以及包含酰氨基烷基氨基甲酸酯前药的药物组合物 的3-氨基丙基次膦酸及其类似物用于治疗疾病或病症如轻度认知障碍,与阿尔茨海默病有关的认知障碍阿尔茨海默氏病,抑郁症,焦虑症和癫痫。 还公开了适用于口服给药和缓释口服剂型的3-氨基丙基次膦酸的氨基氧基烷基氨基甲酸酯前药及其类似物。