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1. 发明申请

WO2012156725A1 DOSE CONTAINER 审中-公开
标题翻译：剂量容器
公开(公告)号：WO2012156725A1
公开(公告)日：2012-11-22
申请号：PCT/GB2012/051082
申请日：2012-05-16
申请人： THE TECHNOLOGY PARTNERSHIP PLC , SELBY, Robert Gordon Maurice , POLLOCK, Neil , CRICHTON, Daniel , BRADSHAW, Douglas Robert Saunders
发明人： SELBY, Robert Gordon Maurice , POLLOCK, Neil , CRICHTON, Daniel , BRADSHAW, Douglas Robert Saunders
IPC分类号： A61M15/00 , A61M15/08
CPC分类号： A61J1/14 , A61J3/07 , A61M11/005 , A61M11/06 , A61M15/0028 , A61M15/0035 , A61M15/0041 , A61M15/0053 , A61M15/0063 , A61M15/0085 , A61M2202/04 , B05B17/06 , B05B17/0638 , B65D25/08
摘要： A unit dose container for holding a single dose of a given liquid, the container comprising: a chamber (8) in which, in use, the given liquid is stored, the chamber having a wall through which, in use, the liquid is to be supplied; a release mechanism (7), at least part of which is internal to, or forms part of the wall of, the chamber, the release mechanism being movable relative to the chamber between first and second positions; and means for allowing the release mechanism (7) to move from the first to the second positions, thereby opening a passage through the wall so that the liquid can exit the chamber (8), the means including at least one flexible wall portion.
摘要翻译：用于保持单剂量给定液体的单位剂量容器，所述容器包括：室（8），其中在使用中储存给定液体，所述腔室具有壁，在使用中，所述液体在所述腔供应; 释放机构（7），其至少一部分位于所述腔室的内部或壁的一部分中，所述释放机构可相对于所述腔室在第一和第二位置之间移动; 以及用于允许释放机构（7）从第一位置移动到第二位置的装置，从而打开通过壁的通道，使得液体可以离开室（8），该装置包括至少一个柔性壁部分。

2. 发明申请

WO2012156724A2 SEPARABLE MEMBRANE IMPROVEMENTS 审中-公开
标题翻译：可分离的膜改进
公开(公告)号：WO2012156724A2
公开(公告)日：2012-11-22
申请号：PCT/GB2012/051081
申请日：2012-05-16
申请人： THE TECHNOLOGY PARTNERSHIP PLC , CRICHTON, Daniel , SELBY, Robert Gordon Maurice , POOLEY, David Martin
发明人： CRICHTON, Daniel , SELBY, Robert Gordon Maurice , POOLEY, David Martin
IPC分类号： B05B17/06
CPC分类号： B05B17/0646
摘要： A liquid droplet production apparatus comprising a perforate membrane, a means for supplying liquid to one side of the membrane, an actuator for vibrating the membrane said vibration causing liquid droplets to be ejected from the other side of the membrane, in which magnetic force is used to connect the actuator to the membrane so that the vibration can be transmitted.
摘要翻译：一种液滴制造装置，包括穿孔膜，用于向膜的一侧供给液体的装置，用于使膜振动的致动器，所述振动使得从使用磁力的膜的另一侧喷出液滴将致动器连接到膜上，从而可以传递振动。

3. 发明申请

WO2021087249A1 AGENT DELIVERY SYSTEMS, DEVICES, AND METHODS 审中-公开
公开(公告)号：WO2021087249A1
公开(公告)日：2021-05-06
申请号：PCT/US2020/058192
申请日：2020-10-30
申请人： THERMALIN, INC. , MEGLAN, Dwight , BERENSON, Richard William , MICHAEL, Mervyn Dodson , CHUNG, Charles , CONTRERAS, Daniel , HARRISON, Kimberly , YANG, Xue'en , SELBY, Robert Gordon Maurice , GREENENKO, Alon , FLAHERTY, J., Christopher
发明人： MEGLAN, Dwight , BERENSON, Richard William , MICHAEL, Mervyn Dodson , CHUNG, Charles , CONTRERAS, Daniel , HARRISON, Kimberly , YANG, Xue'en , SELBY, Robert Gordon Maurice , GREENENKO, Alon , FLAHERTY, J., Christopher
IPC分类号： A61M5/142 , A61M5/162 , A61M5/168
摘要： A system for delivering an agent to a patient, comprises a delivery device. The delivery device is configured to deliver a first agent to the patient, and comprises a reservoir, a transcutaneous delivery assembly, a pumping mechanism, a control module, a power supply, and a housing. The reservoir stores the first agent. The transcutaneous delivery assembly delivers the first agent to the patient transcutaneously. The pumping mechanism receives the first agent from the reservoir and propels the first agent to the transcutaneous delivery assembly. The control module controls at least the pumping mechanism. The power supply provides energy to at least the control module and the pumping mechanism. The housing surrounds at least the pumping mechanism. Methods of delivering an agent to the patient are also described.

4. 发明申请

WO2015173569A1 AEROSOLISATION ENGINE FOR LIQUID DRUG DELIVERY BACKGROUND 审中-公开
标题翻译：用于液体药物输送的喷雾发动机背景技术
公开(公告)号：WO2015173569A1
公开(公告)日：2015-11-19
申请号：PCT/GB2015/051413
申请日：2015-05-13
申请人： THE TECHNOLOGY PARTNERSHIP PLC
发明人： STRANGE, Daniel Geoffrey Tyler , SELBY, Robert Gordon Maurice , GUION, Romain Ulysses Gabriel , PHILLIPS, Timothy James , RICHARDSON, William
IPC分类号： A61M11/00
CPC分类号： A61M11/007 , A61F9/0008 , A61M11/002 , A61M11/003 , A61M15/0021 , A61M15/0065 , A61M15/08 , A61M2205/0238 , A61M2205/8225 , A61M2205/8281 , A61M2210/0612 , B05B1/262 , B05B14/00
摘要： A spray device for generating an aerosol of a liquid such as a medicament. The device includes a perforate element comprising one or more nozzles, each nozzle having an inlet and an outlet. A drive mechanism causes, in use, liquid to be driven through the one or more nozzles, thereby forming a liquid spray having one or more streams of liquid. At least one impaction surface is provided onto which, in use, the liquid impacts, the impaction surface being located downstream of the nozzle outlet(s).
摘要翻译：一种用于产生诸如药物的液体气溶胶的喷雾装置。该装置包括一个包括一个或多个喷嘴的穿孔元件，每个喷嘴具有入口和出口。驱动机构在使用中导致液体被驱动通过一个或多个喷嘴，从而形成具有一个或多个液体流的液体喷雾。提供至少一个冲击表面，在使用中液体冲击到其上，冲击表面位于喷嘴出口的下游。

5. 发明申请

WO2016075433A1 LOW COST IMPINGING JET NOZZLE 审中-公开
标题翻译：低成本喷射喷嘴
公开(公告)号：WO2016075433A1
公开(公告)日：2016-05-19
申请号：PCT/GB2015/053221
申请日：2015-10-27
申请人： THE TECHNOLOGY PARTNERSHIP PLC
发明人： SELBY, Robert Gordon Maurice , STRANGE, Daniel Geoffrey Tyler , RICHARDSON, Will
IPC分类号： A61M11/00 , A61M15/00 , B29C45/26 , B05B1/26
CPC分类号： B05B1/26 , A61F9/0008 , A61M11/00 , A61M15/0003 , A61M15/08 , A61M2205/75 , A61M2207/00 , B05B1/34
摘要： A spray device for generating a slow moving aerosol, whereby the aerosol is generated from at least two impinging jets and the jets are formed by forcing liquid through a single moulded plastic nozzle assembly comprising: a. one or more thin walled sections (typically 200 µm) (18) where the thin wall sections (18) are supported by one or more thick walled sections (typically > 200 µm) (17, 19). b. at least two opposing holes (13) with hydraulic diameters of 5 pm to 100µm (typically 30 µm) and axes at an angle of between 55 and 125 degrees (preferably 90 degrees) to an external surface of the thin walled section (18), such that the projected areas of the holes (13) at least partially intersect at the outlet side of the nozzle.
摘要翻译：一种用于产生缓慢移动的气溶胶的喷射装置，由此由至少两个冲击射流产生气溶胶，并且喷射通过迫使液体通过单个模制塑料喷嘴组件形成，包括：a。一个或多个薄壁部分（通常<200μm）（18），其中薄壁部分（18）由一个或多个厚壁部分（通常>200μm）（17,19）支撑。湾至少两个水平直径为5μm至100μm（通常为30μm）的相对孔（13）和与薄壁部分（18）的外表面55度至125度（优选90度）的角度的轴线，使得孔（13）的投影面积在喷嘴的出口侧至少部分地相交。

6. 发明申请

WO2015004449A1 SEPARABLE MEMBRANE IMPROVEMENTS 审中-公开
标题翻译：可分离的膜改进
公开(公告)号：WO2015004449A1
公开(公告)日：2015-01-15
申请号：PCT/GB2014/052084
申请日：2014-07-09
申请人： THE TECHNOLOGY PARTNERSHIP PLC
发明人： SELBY, Robert Gordon Maurice , STRANGE, Daniel Geoffrey Tyler
IPC分类号： B05B17/06 , B05B17/00
CPC分类号： B05B17/0646 , A61M11/005
摘要： An apparatus is provided for nebulising a liquid from a liquid supply through a membrane comprising first and second surfaces and a plurality of apertures extending through the membrane. The apparatus comprises an area for receiving a liquid supply, arranged to deliver a liquid to the first surface of the membrane, a vibrator member, arranged to vibrate the membrane to eject liquid droplets from the front surface of the membrane on vibration; and a mechanical coupling means, arranged to provide a removable mechanical clamping force for clamping the membrane to the vibrator member. Various means for implementing the mechanical coupling are provided, and liquid containers and membranes for use in the device are proposed.
摘要翻译：提供了一种用于通过包括第一和第二表面的膜和延伸穿过膜的多个孔的液体来雾化液体的装置。该装置包括用于接收液体供应的区域，其布置成将液体输送到膜的第一表面;振动器构件，被布置成振动膜以在振动时从膜的前表面喷出液滴; 以及机械联接装置，其布置成提供用于将膜夹持到振动器构件的可移除的机械夹紧力。提供了用于实现机械联接的各种手段，并且提出了用于装置中的液体容器和膜。

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