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    • 10. 发明申请
    • COMPOSITIONS AND METHODS OF DELIVERING BLEACHING AGENTS TO TEETH
    • 将漂白剂递送给TEETH的组合物和方法
    • WO2005058268A1
    • 2005-06-30
    • PCT/US2004/042974
    • 2004-12-17
    • THE PROCTER & GAMBLE COMPANYSCOTT, Douglas, CraigGHOSH, Chanchal, Kumar
    • SCOTT, Douglas, CraigGHOSH, Chanchal, Kumar
    • A61K7/16
    • A61K8/8111A61K8/22A61Q11/00
    • The present invention relates to compositions and methods of whitening teeth of a subject in need thereof, by applying a safe and effective amount of a composition to a plurality of teeth, the composition comprising: a. a safe and effective amount of a bleaching agent; b. a safe and effective amount of a water insoluble solid phase; c. a safe and effective amount of a water soluble liquid phase; wherein the ratio of the water insoluble solid phase to water soluble liquid phase is from about 1:4 to about 4:1; wherein the composition is applied for a sufficient period of time to achieve whitening; and wherein in one embodiment the composition has a Whitening Index of from about 0.5 to about 4. The composition comprises a hydrophobically modified polymer. The present invention also relates to a delivery system comprising the present compositions used with an integral carrier, e.g. a strip material, dental tray or sponge material.
    • 本发明涉及通过将安全有效量的组合物施用于多个牙齿来增加有需要的受试者牙齿的组合物和方法,所述组合物包含:a。 安全有效量的漂白剂; 湾 安全有效量的水不溶性固相; C。 安全有效量的水溶性液相; 其中水不溶性固相与水溶性液相的比例为约1:4至约4:1; 其中组合物施用足够的时间以实现美白; 并且其中在一个实施方案中,所述组合物具有约0.5至约4的美白指数。所述组合物包含疏水改性的聚合物。 本发明还涉及包含与整体载体一起使用的本发明组合物的递送系统。 条带材料,牙科托盘或海绵材料。