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1. 发明申请

WO1988009790A1 4H-3,1-BENZOXAZIN-4-ONE COMPOUNDS AND SERINE PROTEASE-INHIBITING MEDICINAL COMPOSITION CONTAINING SAME 审中-公开
标题翻译： 4H-3,1-BENZOXAZIN-4-ONE化合物和含有其的丝氨酸蛋白酶抑制药物组合物
公开(公告)号：WO1988009790A1
公开(公告)日：1988-12-15
申请号：PCT/JP1988000556
申请日：1988-06-09
申请人： TEIJIN LIMITED , KOKUBO, Masayuki , FUJII, Katsuhiko , OSHIDA, Junichi , TOMIMORI, Koji , UEJIMA, Yasuhide
发明人： TEIJIN LIMITED
IPC分类号： C07D265/22
CPC分类号： C07D265/22 , C07D265/24 , C07D265/26 , C07K5/00 , Y02P20/55
摘要： 4H-3,1-Benzoxazin-4-one compounds represented by general formula (I) (wherein R represents a hydrogen atom or an alkyl group, A represents an amino acid residue or a peptide containing 2 to 3 amino acid residues (provided that side chains of these amino acid residues may be protected by protective groups), X represents an alkyl group, a fluoroalkyl group, OR1 or NHR1 (wherein R1 represents an alkyl group) and Y represents an amino group-protective group) and their salts are disclosed. They show an excellent inhibitory action on serine protease, particularly human leukocyte elastase, thus being useful as the component of elastase-inhibiting drugs.

2. 发明申请

WO1991012245A1 4H-3,1-BENZOXAZIN-4-ONE COMPOUND AND ELASTASE INHIBITOR COMPOSITION CONTAINING THE SAME 审中-公开
标题翻译： 4H-3,1-苄氧基-4-酮化合物和含有该化合物的弹性酶抑制剂组合物
公开(公告)号：WO1991012245A1
公开(公告)日：1991-08-22
申请号：PCT/JP1991000183
申请日：1991-02-15
申请人： TEIJIN LIMITED , OSHIDA, Junichi , KAWABATA, Hiroshi , KATO, Yoshinori , KOKUBO, Masayuki , UEJIMA, Yasuhide , SATO, Osami , FUJII, Katsuhiko
发明人： TEIJIN LIMITED
IPC分类号： C07D265/24
CPC分类号： C07D413/04 , A61K38/00 , C07D265/24 , C07K5/0207
摘要： A 4H-3,1-benzoxazin-4-one compound of general formula (I), salts thereof, and pharmaceutical composition containing the same as the active ingredient. They have a protease inhibiting effect, particularly a selective inhibiting effect on a human leukocyte elastase and are excellent in water solubility and residence in the tissue.

3. 发明申请

WO1990010014A1 NEW VITAMIN B12 DERIVATIVE, PRODUCTION THEREOF, AND APPLICATION THEREOF 审中-公开
标题翻译：新维生素B12衍生物，其生产方法及其应用
公开(公告)号：WO1990010014A1
公开(公告)日：1990-09-07
申请号：PCT/JP1990000253
申请日：1990-02-28
申请人： TEIJIN LIMITED , TORAYA, Tetsuo , ISHIDA, Atsuhiko , UEJIMA, Yasuhide , FUJII, Katsuhiko
发明人： TEIJIN LIMITED
IPC分类号： C07H23/00
CPC分类号： C07H23/00 , C07F15/065
摘要： A vitamin B12 derivative of formula (I) and salts thereof, wherein L represents a ligand bound to the cobalt atom of the corrin ring, B represents a base having a heterocyclic structure, and R represents an (un)substituted hydrocarbon group.

4. 发明申请

WO1996004903A1 VASCULAR SMOOTH MUSCLE CELL MIGRATION INHIBITOR 审中-公开
标题翻译：血管平滑肌细胞移植抑制剂
公开(公告)号：WO1996004903A1
公开(公告)日：1996-02-22
申请号：PCT/JP1995001492
申请日：1995-07-27
申请人： TEIJIN LIMITED , MASEGI, Tsukio , TOMIMORI, Koji , WATANABE, Kunihito
发明人： TEIJIN LIMITED
IPC分类号： A61K31/215
CPC分类号： A61K31/5575
摘要： A vascular smooth muscle cell migration inhibitor and a preventive or remedy for post-PTCA restenosis, each containing an isocarbacyclin represented by general formula (1) and/or an enantiomer thereof as the active ingredient, wherein W represents o-, m- or p-phenylene, C3-C7 cycloalkylene or thiophenediyl; R represents hydrogen, methyl, ethyl or vinyl; R represents optionally substituted linear or branched C3-C9 alkyl, alkenyl or alkynyl, or C3-C7 cycloalkyl; R represents hydrogen, C1-C10 alkyl, phenyl, naphthyl, benzyl or a mono-equivalent cation; Z and Z represent each independently hydrogen, tri(C1-C7 hydrocarbyl)silyl or a group that forms an acetal or ester linkage together with the oxygen atom to which it is bonded; n represents 0 or 1; and m represents an integer of 0 to 4.
摘要翻译：血管平滑肌细胞迁移抑制剂和用于PTCA后再狭窄的预防或治疗，每种含有由通式（1）表示的异卡巴环素和/或其对映异构体作为活性成分，其中W表示o-，m-或p 亚苯基，C3-C7亚环烷基或噻吩二基; R 1表示氢，甲基，乙基或乙烯基; R 2表示任选取代的直链或支链C 3 -C 9烷基，烯基或炔基或C 3 -C 7环烷基; R 30表示氢，C 1 -C 10烷基，苯基，萘基，苄基或单当量阳离子; Z 10和Z 20各自独立地表示氢，三（C 1 -C 7烃基）甲硅烷基或与其键合的氧原子一起形成缩醛或酯键的基团; n表示0或1; m表示0〜4的整数。

5. 发明申请

WO1987003284A1 VASCULARIZATION FACTOR AND PROCESS FOR ITS PREPARATION 审中-公开
标题翻译：血管因子及其制备方法
公开(公告)号：WO1987003284A1
公开(公告)日：1987-06-04
申请号：PCT/JP1986000591
申请日：1986-11-19
申请人： TEIJIN LIMITED , FUKUMOTO, Yuji , OHTSU, Akira , FUJII, Katsuhiko
发明人： TEIJIN LIMITED
IPC分类号： C07K05/04
CPC分类号： A61K35/44
摘要： A vascularization factor which can be yielded by endothelial cells of a blood vessel, which is absorbed by an agarose gel having heparin immobilized thereon and is eluted by 0.7 M to 1.0 M sodium chloride, which is adsorbed by a diethylaminoethyl anion exchanger and is eluted by 0.2 M to 0.4 M sodium chloride, and which has a molecular weight of about 5,000 to 10,000. This factor can be utilized in treating ischemic diseases and wounds.

6. 发明申请

WO1988000182A1 'gamma'-L-GLUTAMYL-L-CYSTEINE ETHYL ESTER AND DRUG CONTAINING IT AS EFFECTIVE INGREDIENT 审中-公开
标题翻译：（GAMMA）-L-GLUTAMYL-L-CYSTEINE ETHYL ESTER和含有有效成分的药物
公开(公告)号：WO1988000182A1
公开(公告)日：1988-01-14
申请号：PCT/JP1987000475
申请日：1987-07-07
申请人： TEIJIN LIMITED , KITAHARA, Shigehisa , OHTSU, Akira , FUJII, Katsuhiko
发明人： TEIJIN LIMITED
IPC分类号： C07C149/243
CPC分类号： A61K31/195 , A61K31/22 , C07K5/02
摘要： gamma-L-Glutamyl-L-cysteine ethyl ester effective in increasing the tissue glutathione level and a drug containing said ester for treating liver diseases, cataract, kidney diseases, etc.

7. 发明申请

WO1998026119A1 PLUSH FABRIC CAPABLE OF GENERATING LONG/SHORT PILES, PILL-LIKE FABRIC AND METHOD OF PRODUCTION THEREOF 审中-公开
标题翻译：用于生产长/短绒的普通织物，类似布的织物及其生产方法
公开(公告)号：WO1998026119A1
公开(公告)日：1998-06-18
申请号：PCT/JP1997004581
申请日：1997-12-12
申请人： TEIJIN LIMITED , KASAOKA, Katsuyuki , TAKAHASHI, Shigeru , MATSUMOTO, Mitsuo , KIMURA, Akio
发明人： TEIJIN LIMITED
IPC分类号： D03D27/00
CPC分类号： D04B1/04 , D03D15/04 , D03D27/00 , D04B21/04 , Y10T428/23936 , Y10T428/23957
摘要： A plush fabric forming cut piles by synthetic resin multi-filament yarns, wherein the synthetic resin multi-filament yarn comprises a mixed yarn of a crimped multi-filament yarn and a high heat-shrinkable uncrimped multi-filament yarn which has a higher heat shrinkage ratio as a whole than the crimped multi-filament yarn and has thick and thin portions in a longitudinal direction and whose thick portion has a higher heat shrinkage ratio than the thin portion. When the plush fabric is heat-treated, a long-and-short pile fabric having a unique appearance can be obtained. Particularly when at least the distal end portions of the crimped multi-filaments among the multi-filament mixed yarn forming the plush are interlaced, a pill-like fabric having a corrugation feel can be obtained.
摘要翻译：一种由合成树脂复丝纱切成的毛绒织物，其中合成树脂复丝包括卷曲复丝纱的混合纱线和具有较高热收缩率的高热收缩未卷曲复丝纱线比率比卷曲复丝纱长，并且在长度方向上具有厚薄部分，并且其厚部具有比薄部分更高的热收缩率。当毛绒织物被热处理时，可以获得具有独特外观的长短绒毛织物。特别是在形成毛绒的复丝混纺纱中的卷曲多丝丝的至少前端部交织时，可以得到具有波纹感的片状织物。

8. 发明申请

WO1998021396A1 DYED FILAMENT YARN HAVING CLEAR HUE 审中-公开
标题翻译：染色纱线有清洁色调
公开(公告)号：WO1998021396A1
公开(公告)日：1998-05-22
申请号：PCT/JP1997004045
申请日：1997-11-06
申请人： TEIJIN LIMITED , AOYAMA, Saori , SUZUKI, Togi
发明人： TEIJIN LIMITED
IPC分类号： D06P03/52
CPC分类号： D01F6/84 , D06P1/0004 , D06P1/0032 , D06P1/0096 , D06P3/54
摘要： A colored aromatic polyester filament yarn having a clear hue, wherein the filament comprises an aromatic polyester polymer having a glass transition temperature (Tg) of 65 DEG C or below and prepared by copolymerizing an aliphatic dicarboxylic acid component and/or an aliphatic diol component, while the whole yarn exhibits a visually homogeneous dyed state despite the presence of dyed spots in the longitudinal direction in each filament constituting the yarn, and the chroma C* value represented by the L*a*b* color space of the yarn dyed with a 1 % (owf) aqueous solution of a disperse dye composed mainly of C.I. Disperse Blue 56 is at least 36.
摘要翻译：具有透明色调的有色芳香族聚酯长丝纱，其中，长丝包含玻璃化转变温度（Tg）为65℃以下且通过使脂肪族二羧酸成分和/或脂肪族二醇成分共聚制备的芳香族聚酯聚合物，尽管在构成纱线的每根细丝中，尽管在长丝方向上存在着染色斑点，但是整个纱线表现出视觉上均匀的染色状态，并且由染色的纱线的L * a * b *颜色空间表示的色度C *值主要由CI组成的分散染料的1％（owf）水溶液分散蓝56至少为36。

9. 发明申请

WO1997045583A1 METHOD OF FILLING HOLLOW FIBER WITH GEL 审中-公开
标题翻译：填充中空纤维与凝胶的方法
公开(公告)号：WO1997045583A1
公开(公告)日：1997-12-04
申请号：PCT/JP1997001689
申请日：1997-05-20
申请人： TEIJIN LIMITED , IZAWA, Hajime , SUZUKI, Togi
发明人： TEIJIN LIMITED
IPC分类号： D06M15/00
CPC分类号： D06M23/00 , D01D5/24
摘要： A method of efficiently filling the hollow of a hollow fiber with gel without requiring specific set-ups such as a pressure-proof device, making it possible to mass-produce such fibers on an industrial basis, comprising the steps of dipping a hollow fiber having dispersedly communication holes leading from the fiber surface to the hollow in a liquid having gel formation capability, then leaving the hollow fiber standing at room temperature so as to fill the hollow with the liquid through the communication holes, and gelatinizing the liquid.
摘要翻译：一种在不需要诸如耐压装置的特定装置之前有效地填充中空纤维的中空纤维的方法，使得可以在工业上大量生产这种纤维，包括以下步骤：将具有从具有凝胶形成能力的液体中将纤维表面引导到中空的分散连通孔，然后将中空纤维放置在室温下，以便通过连通孔填充中空液体并使液体糊化。

10. 发明申请

WO1997044510A1 AROMATIC POLYAMIDE BRISTLE 审中-公开
标题翻译：芳香族聚酰胺
公开(公告)号：WO1997044510A1
公开(公告)日：1997-11-27
申请号：PCT/JP1997001688
申请日：1997-05-20
申请人： TEIJIN LIMITED , KAKIHARA, Ryuichi , NOMA, Takashi
发明人： TEIJIN LIMITED
IPC分类号： D01F06/60
CPC分类号： D01F6/605 , Y10T428/2913 , Y10T428/2969
摘要： An aromatic polyamide bristle which has excellent resistance to chemicals, such as acids and alkalis, and good rigidity, mechanical properties, such as strength and modulus of elasticity, and heat resistance and is suitable for use in tension members, fishing guts, catheters and other industrial applications. This bristle is formed from an optically isotropic solution and has a monofilament fineness of 10 to 200 deniers, a flatness of not more than 3, and, as mechanical properties, a tensile strength of not less than 15 g/de, an elongation at break of not more than 4.0 %, and an initial modulus of not less than 500 g/de.
摘要翻译：具有优异的耐酸碱性的化学物质，具有良好的刚性，机械性能，如强度，弹性模量和耐热性的芳香族聚酰胺刷毛，适用于拉伸部件，钓鱼肠，导管等工业应用。该刷毛由光学各向同性溶液形成，单丝细度为10〜200旦，平坦度为3以下，作为机械性能，拉伸强度为15g / d以上，断裂伸长率不大于4.0％，初始模量不小于500g / de。

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