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1. 发明申请

WO2009018367A2 NOVEL SALT FORMS OF (2S)-(4E)-N-METHYL-5-[3-(5-METHOXYPYRIDIN)YL]-4-PENTEN-2-AMINE 审中-公开
标题翻译：（2S） - （4E）-N-甲基-5- [3-（5-甲氧基吡啶）基] -4-丁烯-2-胺的新型盐形式
公开(公告)号：WO2009018367A2
公开(公告)日：2009-02-05
申请号：PCT/US2008/071631
申请日：2008-07-30
申请人： TARGACEPT, INC. , DULL, Gary Maurice , MUNOZ, Julio A. , GENUS, John , BHATTI, Balwinder Singh , YOUNG, Jennifer A. , BENCHERIF, Merouane , JAMES, John W. , WILLIAMS, Michael G. , JORDAN, Kristen , LIPPIELLO, Patrick M. , FORDHAM-MEIER, Beth
发明人： DULL, Gary Maurice , MUNOZ, Julio A. , GENUS, John , BHATTI, Balwinder Singh , YOUNG, Jennifer A. , BENCHERIF, Merouane , JAMES, John W. , WILLIAMS, Michael G. , JORDAN, Kristen , LIPPIELLO, Patrick M. , FORDHAM-MEIER, Beth
IPC分类号： C07D213/62 , A61K31/44 , A61P25/28
CPC分类号： C07D213/62
摘要： Salts of (2S)-(4E)-N-methyl-5-[3-(5-methoxypyridin)yl]-4-penten-2-amine, methods for their preparation, pharmaceutical compositions comprising said salts, and their use are disclosed. The salts can be administered to patients susceptible to or suffering from conditions and disorders, such as central nervous system disorders, to treat or prevent such disorders.
摘要翻译：（2S） - （4E）-N-甲基-5- [3-（5-甲氧基吡啶）基] -4-戊烯-2-胺的盐，其制备方法，包含所述盐的药物组合物及其用途披露。盐可以施用于易患或患有诸如中枢神经系统疾病的病症和障碍的患者，以治疗或预防这些疾病。

2. 发明申请

WO2013162680A1 CONFORMING SECUREMENT ARTICLES AND METHODS OF USE 审中-公开
标题翻译：符合安全条款和使用方法
公开(公告)号：WO2013162680A1
公开(公告)日：2013-10-31
申请号：PCT/US2013/026621
申请日：2013-02-19
申请人： 3M INNOVATIVE PROPERTIES COMPANY , KARIM, Naimul , WILLIAMS, Michael G.
发明人： KARIM, Naimul , WILLIAMS, Michael G.
IPC分类号： A61M25/02 , A61F13/02
CPC分类号： C09J7/02 , A61F13/023 , A61L15/58 , A61M25/02 , A61M2025/0266 , A61M2025/0273 , A61M2207/00 , B32B1/08 , B32B5/024 , B32B5/18 , B32B27/00 , B32B37/12 , B32B2305/022 , B32B2305/188 , B32B2405/00 , B32B2535/00 , C09J5/00 , C09J7/20 , C09J2201/16 , Y10T156/10 , Y10T428/1476 , Y10T428/15 , Y10T428/24314 , Y10T428/24612
摘要： An article (100) for securing an object to a surface is provided. The article comprises a conformable backing (30) having top and bottom major surfaces and a perimeter edge, an adhesive (36) coated on at least a portion of the bottom major surface of the backing, and a self- supporting carrier (50) rclcasably adhered to the top major surface of the backing, the carrier having spaced- apart first and second sections (50), each section having a central edge. The central edges define opposing borders of an object-conformable region (37) of the backing. On opposite sides of the object-conformable region, the backing comprises two anchor regions. Also provided is a method of using the article to secure an object to the surface. The method comprises using at least one section of the carrier to conform the backing to at least a portion of the topological shape of the object to be secured to the surface.
摘要翻译：提供了用于将物体固定到表面的物品（100）。该制品包括具有顶部和底部主表面和周边边缘的适形背衬（30），涂覆在背衬的底部主表面的至少一部分上的粘合剂（36）和可自由支撑的载体（50）粘附到背衬的顶部主表面上，载体具有间隔开的第一和第二部分（50），每个部分具有中心边缘。中心边缘限定背衬的物体适形区域（37）的相对边界。在物体相容区域的相对侧上，背衬包括两个锚定区域。还提供了使用该物品将物体固定到表面的方法。该方法包括使用载体的至少一个部分使背衬与要固定到表面的物体的拓扑形状的至少一部分相一致。

3. 发明申请

WO2013122852A1 BIOLOGICAL STERILIZATION INDICATOR DEVICES AND METHODS OF USE 审中-公开
标题翻译：生物灭菌指示剂装置及其使用方法
公开(公告)号：WO2013122852A1
公开(公告)日：2013-08-22
申请号：PCT/US2013/025500
申请日：2013-02-11
申请人： 3M INNOVATIVE PROPERTIES COMPANY , AHIMOU, Francois , CHANDRAPATI, Sailaja , HALVERSON, Kurt J. , WEBB, Heather M. , WILLIAMS, Michael G.
发明人： AHIMOU, Francois , CHANDRAPATI, Sailaja , HALVERSON, Kurt J. , WEBB, Heather M. , WILLIAMS, Michael G.
IPC分类号： C12Q1/22
CPC分类号： C12Q1/22 , G01N21/6428 , G01N2201/061
摘要： A biological sterilization indicator device is provided. The device comprises a body, a plurality of test microorganisms, and an oxygen-modulated first fluorescent sensor. The body comprises a first layer attached to a second layer, forming at least one isolatable microchamber and at least one primary passageway that provides fluidic communication between ambience and the at least one microchamber. The microchamber has an isolated volume of about 0.5 microliters to about 9.5 microliters. The plurality of test microorganisms and the oxygen-modulated first fluorescent sensor are disposed in the microchamber. A method of using the device to determine the effectiveness of a sterilization process is also provided.
摘要翻译：提供生物灭菌指示装置。该装置包括主体，多个测试微生物和氧调制的第一荧光传感器。主体包括附接到第二层的第一层，形成至少一个可隔离的微室和至少一个主要通道，其提供环境与至少一个微室之间的流体连通。微室具有约0.5微升至约9.5微升的隔离体积。多个测试微生物和氧调制的第一荧光传感器设置在微室中。还提供了使用该装置来确定灭菌过程的有效性的方法。

4. 发明申请

WO2007012932A1 MESSAGING MIDDLEWARE DYNAMIC, CONTINUOUS SEARCH AND RESPONSE AGENT SYSTEM 审中-公开
标题翻译：消息中间件动态，连续搜索和响应代理系统
公开(公告)号：WO2007012932A1
公开(公告)日：2007-02-01
申请号：PCT/IB2006/001888
申请日：2006-07-07
申请人： NOKIA CORPORATION , NOKIA INC. , WILLIAMS, Michael G.
发明人： WILLIAMS, Michael G.
IPC分类号： G06F17/30
CPC分类号： G06F17/30864 , H04L51/00
摘要： A technique is provided for searching for information on an Intranet or other private network implemented in a corporation or other business entity or organization, featuring an agent in the Intranet that scans email, messaging and/or Intranet resources and provides information in response to search request from a requesting node. In operation, the agent scans the dynamic flow of messaging for search items and level of authority and issues queries on behalf of the requesting node to regulate the secrecy and privacy of the information on the Intranet. In particular, a set of software agents scan email, messaging or Intranet resources during transmission and after storage on the Intranet. Eact agent issues queries on behalf of verified, authenticated and/or authorized individuals, to messaging accounts related to those messages or documents, and responds to queries from agents in the automatic mode.
摘要翻译：提供了一种用于搜索在公司或其他商业实体或组织中实现的内联网或其他专用网络上的信息的技术，其特征在于内联网中的代理扫描电子邮件，消息传递和/或内联网资源，并响应于搜索请求提供信息来自请求节点。在操作中，代理扫描用于搜索项的消息的动态流程和权限级别，并且代表请求节点发出查询以规范在内联网上的信息的保密性和隐私性。特别地，一组软件代理在传输和在内联网上存储之后扫描电子邮件，消息或内联网资源。 Eact代理人代表已验证的，经过身份验证的和/或授权的个人发送与这些消息或文档相关的邮件帐户的查询，并响应来自自动模式的代理的查询。

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