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1. 发明申请

WO2008010668A1 20(S -GINSENOSIDE RG3 AS AN ANTI-ANGIOGENIC COMPOSITION 审中-公开
标题翻译： 20（S-GINSENOSIDE RG3作为抗血小板衍生物
公开(公告)号：WO2008010668A1
公开(公告)日：2008-01-24
申请号：PCT/KR2007/003473
申请日：2007-07-18
申请人： SK CHEMICALS CO., LTD. , SUN, Won Suck , CHOI, Wonrack , CHOI, Sang-Keun , HAN, Chang-Kyun , YOON, Mi-Sun , KIM, Tae-Kon , KIM, Taek-Soo , IM, Guang-Jin , SHIN, Dong-Chul , KIM, Woong-Sik , OH, Joon-Gyo , SUNG, Jin-Heung , UM, Key-An , CHO, Yong-Baik
发明人： SUN, Won Suck , CHOI, Wonrack , CHOI, Sang-Keun , HAN, Chang-Kyun , YOON, Mi-Sun , KIM, Tae-Kon , KIM, Taek-Soo , IM, Guang-Jin , SHIN, Dong-Chul , KIM, Woong-Sik , OH, Joon-Gyo , SUNG, Jin-Heung , UM, Key-An , CHO, Yong-Baik
IPC分类号： A61K36/258 , A61K31/704 , A61K31/56
CPC分类号： A61K36/258 , A61K31/56 , A61K31/704
摘要： The present invention relates to an anti-angiogenic composition comprising ginsenoside Rg3. In particular, the present invention relates to an anti-angiogenic composition comprising 20(S)-ginsenoside Rg3 at a concentration of from 40 to 60 %(w/v) which shows excellent inhibitory effect on angiogenesis and tumor growth by inhibiting the activity of vascular endothelial growth factor receptor-1 (VEGFR-1) and lowering in vivo level of vascular endothelial growth factor (VEGF).
摘要翻译：本发明涉及包含人参皂苷Rg3的抗血管生成组合物。特别地，本发明涉及一种抗血管生成组合物，其包含浓度为40〜60％（w / v）的20（S） - 人参皂甙Rg3，其对血管生成和肿瘤生长具有优异的抑制作用血管内皮生长因子受体-1（VEGFR-1）和降低血管内皮生长因子（VEGF）的体内水平。

2. 发明申请

WO2008063024A1 INCLUSION COMPLEX OF SIBUTRAMINE AND BETA-CYCLODEXTRIN 审中-公开
标题翻译：包含SIBUTRAMINE和BETA-CYCLODEXTRIN的复合物
公开(公告)号：WO2008063024A1
公开(公告)日：2008-05-29
申请号：PCT/KR2007/005922
申请日：2007-11-22
申请人： SK CHEMICALS CO., LTD. , KIM, Jae-Sun , KIM, Nam Ho , LEE, Jin Young , LEE, Nam Kyu , OH, Joon Gyo , HWANG, Yong Youn , SHIN, Dong-Chul , LEE, Yoon-Jung , UM, Key An , KIM, Sun Ho , SUNG, Jin-Heung
发明人： KIM, Jae-Sun , KIM, Nam Ho , LEE, Jin Young , LEE, Nam Kyu , OH, Joon Gyo , HWANG, Yong Youn , SHIN, Dong-Chul , LEE, Yoon-Jung , UM, Key An , KIM, Sun Ho , SUNG, Jin-Heung
IPC分类号： A61K47/48
CPC分类号： A61K31/135 , A61K47/6951 , B82Y5/00 , C08B37/0015
摘要： The present invention relates to a sibutramine-containing inclusion complex having superior storage stability, and particularly to a pharmaceutically stable inclusion complex suitable for the drug formulation, which prepared by reacting a sibutramine (N,N-dimethyl-l-[l-(4-chlorophenyl)-cyclobutyl]-3-methylbutylamine) of Formula 1 and beta- cyclodextrin in a predetermined ratio, its preparation method and a pharmaceutical composition comprising the same.
摘要翻译：本发明涉及具有优异储存稳定性的西布曲明含量复合物，特别涉及适用于药物制剂的药学上稳定的包合物，其通过使西布曲明（N，N-二甲基-1- [1-（4 - 氯苯基） - 环丁基] -3-甲基丁胺）和β-环糊精，其制备方法和包含其的药物组合物。

3. 发明申请

WO2007049868A1 STABILIZED PHARMACEUTICAL ORAL PREPARATION CONTAINING CLOPIDOGREL BISULFATE 审中-公开
标题翻译：含有双歧杆菌的稳定的药物口服制剂
公开(公告)号：WO2007049868A1
公开(公告)日：2007-05-03
申请号：PCT/KR2006/004046
申请日：2006-10-09
申请人： SK CHEMICALS CO., LTD. , OH, Joon Gyo , SHIN, Dong-Chul , SHIN, Ji Young , YOUN, Won-No , UM, Key An , MIN, Dong-Sun , KIM, Jae-Sun , KIM, Nam Ho , LEE, Nam Kyu
发明人： OH, Joon Gyo , SHIN, Dong-Chul , SHIN, Ji Young , YOUN, Won-No , UM, Key An , MIN, Dong-Sun , KIM, Jae-Sun , KIM, Nam Ho , LEE, Nam Kyu
IPC分类号： A61K31/4365 , A61K9/14 , A61K9/20 , A61K9/48 , A61K47/36
CPC分类号： A61K9/2077 , A61K9/2866 , A61K31/4365
摘要： The present invention relates to a stabilized oral preparation comprising clopidogrel bisulfate, and in particular the oral preparation herein further comprises starch and cellulose along with the crystalline form 1 or form 2 clopidogrel bisulfate, which is susceptible to moisture and produces hydrated product-related impurities when formulated into oral preparations, thus showing storage stability even in the same dosage form with the conventional preparations.
摘要翻译：本发明涉及包含氯吡格雷硫酸氢盐的稳定的口服制剂，特别是本文的口服制剂还包括淀粉和纤维素以及结晶形式1或形式2的氯吡格雷硫酸氢盐，其易受潮湿并产生水合产物相关的杂质，当配制成口服制剂，因此即使以与常规制剂相同的剂型也显示出储存稳定性。

4. 发明申请

WO2008056835A1 AN APPARATUS FOR MOVING THE SNORKEL IN CHEMICAL HEATING IN SNORKEL OF REFINING UTILITY 审中-公开
标题翻译：化学加热装置中精炼加工机组的装置
公开(公告)号：WO2008056835A1
公开(公告)日：2008-05-15
申请号：PCT/KR2006/004614
申请日：2006-11-06
申请人： POSCO ENGINEERING & CONSTRUCTION CO., LTD. , JUNG, Byung-Kyu , SHIN, Dong-Chul , SON, Jung-Oh , LEE, Chai-Rok , KIM, Wan-Sung
发明人： JUNG, Byung-Kyu , SHIN, Dong-Chul , SON, Jung-Oh , LEE, Chai-Rok , KIM, Wan-Sung
IPC分类号： C21C7/00 , C21C7/10
CPC分类号： C21C7/10 , C21C2250/08 , F27D3/16
摘要： Disclosed herein is an apparatus for moving a snorkel in a chemical-heating-in-snorkel (CHIS or CAS-OB) refining facility. The CHIS(CAS-OB) refining facility includes a ladle having a plurality of porous plugs formed in the bottom thereof, a snorkel mounted to an arm vertically movably assembled to a column such that the lower end of the snorkel is deposited in molten steel contained in the ladle, and a blowing lance having a lower end extending into the snorkel, thereby increasing the temperature of the molten steel contained in the ladle. The snorkel moving apparatus includes a snorkel transfer car having wheels mounted at both right and left sides thereof such that the snorkel transfer car can be reciprocated along guides mounted at both right and lefts ends of the arm, the upper part of the snorkel being assembled to the snorkel transfer car, and at least one actuating member, having an operational end thereof connected to one end of the snorkel transfer car, for providing an external force necessary to move the snorkel transfer car forward and backward along the guides. According to the present invention, it is possible to selectively locate the snorkel above one porous plug whose opening state is good, thereby improving the facility operation rate and operation success rate. Therefore, it is possible to exclude the provision of an additional facility due to the poor opening state of the porous plug, thereby accomplishing the construction of an economical and efficient facility.
摘要翻译：本文公开了一种用于在化学加热吸管（CHIS或CAS-OB）精炼设备中移动通气管的设备。 CHIS（CAS-OB）精炼设备包括一个浇包，该浇包具有形成在其底部的多个多孔塞子，一个浮筒，安装在垂直可移动地组装到一个柱上的臂上，使得浮筒的下端沉积在钢水中在钢包中，吹风枪具有延伸到通气管中的下端，从而提高钢包中所含钢水的温度。呼吸管移动装置包括具有安装在其左右两侧的轮的通气管传送车，使得该呼吸管转移车可以沿着安装在臂的左右两端的引导件往复运动，该吸管的上部组装成所述通气管传送车以及至少一个致动构件，其操作端连接到所述通气管传送车的一端，用于提供沿着所述引导件向前和向后移动所述通气管传送车所需的外力。根据本发明，可以将打开状态良好的多孔塞上方的通气管选择性地定位，从而提高设备运转率和运转成功率。因此，由于多孔塞的打开状态不良，可以排除设置附加设备，从而实现经济，高效的设备的构造。

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