专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2004106329A2 NOVEL ANTIINFECTIVE COMPOUNDS AND THEIR PHARMACEUTICAL COMPOSITIONS 审中-公开
标题翻译：新型抗生素化合物及其药物组合物
公开(公告)号：WO2004106329A2
公开(公告)日：2004-12-09
申请号：PCT/IB2004001811
申请日：2004-06-03
申请人： REDDYS LAB LTD DR , MOHAMED TAKHI , DAS JAGATTARAN , NATESAN SELVAKUMAR , TREHAN SANJAY , IQBAL JAVED , MAGADI SITARAM KUMAR
发明人： MOHAMED TAKHI , DAS JAGATTARAN , NATESAN SELVAKUMAR , TREHAN SANJAY , IQBAL JAVED , MAGADI SITARAM KUMAR
IPC分类号： A61P31/04 , C07D405/10 , C07D405/14 , C07D409/10 , C07D409/14 , C07D405/00
CPC分类号： C07D405/10 , C07D405/14 , C07D409/10 , C07D409/14
摘要： The present invention provides novel triazole compounds of formula (I), their pharmaceutically acceptable salts and their pharmaceutical compositions, where all symbols are as defined in the specification
摘要翻译：本发明提供新的式（I）三唑化合物，其药学上可接受的盐及其药物组合物，其中所有符号如说明书中所定义

2. 发明申请

WO2005082892A3 TRIAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM 审中-公开
标题翻译：三唑化合物作为抗菌剂和含有它们的药物组合物
公开(公告)号：WO2005082892A3
公开(公告)日：2006-03-23
申请号：PCT/IB2005000343
申请日：2005-02-11
申请人： REDDYS LAB LTD DR , DAS JAGATTARAN , TAKHI MOHAMED , NATESAN SELVAKUMAR , TREHAN SANJAY , IQBAL JAVED , MAGADI SITARAM KUMAR , KANDEPU SREENIVAS
发明人： DAS JAGATTARAN , TAKHI MOHAMED , NATESAN SELVAKUMAR , TREHAN SANJAY , IQBAL JAVED , MAGADI SITARAM KUMAR , KANDEPU SREENIVAS
IPC分类号： C07D249/06 , C07D401/10 , C07D401/14 , C07D403/00 , C07D403/06 , C07D403/12 , C07D405/12 , C07D405/14 , C07D413/12
CPC分类号： C07D403/06 , C07D249/06 , C07D401/10 , C07D401/14 , C07D403/12 , C07D405/12 , C07D405/14 , C07D413/12
摘要： The present invention relates to novel triazole compounds of formula (I), where all symbols are as defined in the detailed description; their pharmaceutically acceptable salts their stereosiomers thereof, their prodrugs, their rotamers, their pharmaceutical compositions containing them. The present invention also relates to a process for the preparation of the above said novel compounds.
摘要翻译：本发明涉及新的式（I）三唑化合物，其中所有符号如详细描述中所定义; 其药学上可接受的盐，它们的立体异构体，它们的前药，它们的旋转异构体，它们含有它们的药物组合物。本发明还涉及制备上述新化合物的方法。

3. 发明申请

WO2005035528A3 TRIAZOLE DERIVATIVES AS ANTIBACTERIAL AGENTS 审中-公开
标题翻译：三唑衍生物作为抗菌剂
公开(公告)号：WO2005035528A3
公开(公告)日：2005-06-02
申请号：PCT/IB2004003360
申请日：2004-10-14
申请人： REDDYS LAB LTD DR , NATESAN SELVAKUMAR , DAS JAGATTARAN , TAKHI MOHAMED , TREHAN SANJAY , IQBAL JAVED , MAGADI SITARAM KUMAR , KANDEPU SREENIVAS
发明人： NATESAN SELVAKUMAR , DAS JAGATTARAN , TAKHI MOHAMED , TREHAN SANJAY , IQBAL JAVED , MAGADI SITARAM KUMAR , KANDEPU SREENIVAS
IPC分类号： A61K31/395 , A61K31/495 , A61K31/55 , A61P31/00 , C07D401/14 , C07D403/10
CPC分类号： C07D401/14 , C07D403/10
摘要： The present invention relates to novel triazole compounds of formula (I), their prodrugs, their pharmaceutically acceptable salts and their stereoisomers thereof. The present invention also relates to a process for the preparation of the novel compound of the formula (I).
摘要翻译：本发明涉及式（I）的新型三唑化合物，其前药，其药学上可接受的盐及其立体异构体。本发明还涉及制备式（I）的新型化合物的方法。

4. 发明申请

WO2008143649A2 NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS 审中-公开
标题翻译：新型氧杂环丁酮化合物作为抗菌药物
公开(公告)号：WO2008143649A2
公开(公告)日：2008-11-27
申请号：PCT/US2007024843
申请日：2007-12-04
申请人： REDDYS LAB LTD DR , REDDYS LAB INC DR , TAKHI MOHAMED , DAS JAGATTARAN , IQBAL JAVED , SELVAKUMAR NATESAN , KANDEPU SREENIVAS , KUMAR M SITARAM
发明人： TAKHI MOHAMED , DAS JAGATTARAN , IQBAL JAVED , SELVAKUMAR NATESAN , KANDEPU SREENIVAS , KUMAR M SITARAM
IPC分类号： C07D413/02
CPC分类号： C07D413/14 , C07D417/14
摘要： The present invention relates to novel oxazolidinone compounds of formula (I) with antibacterial activity, their pharmaceutically acceptable salts, their stereoisomers, their prodrugs, pharmaceutical compositions comprising the same and to their use as therapeutic agents
摘要翻译：本发明涉及具有抗菌活性的式（I）的恶唑烷酮化合物，其药学上可接受的盐，其立体异构体，其前药，包含它们的药物组合物及其作为治疗剂的用途

5. 发明申请

WO2006029075A2 FIBRATE COMPOUNDS HAVING PPAR AGONIST ACTIVITY 审中-公开
标题翻译：具有PPAR激动剂活性的纤维化合物
公开(公告)号：WO2006029075A2
公开(公告)日：2006-03-16
申请号：PCT/US2005031532
申请日：2005-09-06
申请人： REDDYS LAB LTD DR , REDDYS LAB LTD DR , DAS SAIBAL KUMAR , SINGH SUNIL KUMAR , MADHAVAN GURRAM RANGA , BHUNIYA DEBNATH , IQBAL JAVED , SHARMA SUDHIR KUMAR , CHAKRABARTI RANJAN
发明人： DAS SAIBAL KUMAR , SINGH SUNIL KUMAR , MADHAVAN GURRAM RANGA , BHUNIYA DEBNATH , IQBAL JAVED , SHARMA SUDHIR KUMAR , CHAKRABARTI RANJAN
IPC分类号： A61K31/519 , C07D487/02
CPC分类号： C07D487/04 , C07D239/90
摘要： There are provided derivatives having PPAR agonist activity. The derivatives include compounds and/or their pharmaceutically acceptable salts; the compounds having the formula (I) wherein A has the structure (II) or (III); X is chosen from -CH 2 -, -O-, -NH-, and -S-; Y is chosen from -O-, -NH-, and -S-; Z, which may be located in any position of substitution, is hydrogen or halogen; R 1 and R 2 , which may be the same or different, are independently chosen from hydrogen and C 1 -C 8 alkyl, or R 1 and R 2 together form a carbocyclic ring having from 4 to 6 carbon atoms; R 3 is chosen from hydrogen and C 1 -C 8 alkyl; R 4 , R 5 , and R 6 , which may be the same or different, are independently chosen from hydrogen and C 1 -C 8 alkyl; and n is 1 to 6. Various embodiments and variants are provided. In accordance with other aspects, the invention also provides methods of producing a PPARa agonist activity in a mammal, the methods including administering to the mammal an effective amount of certain derivative(s) of the first aspect of the invention, a method of producing a PPARa agonist activity and a PPARa agonist activity in a mammal, the method including administering to the mammal an effective amount of certain derivative(s); and a pharmaceutical composition that includes the derivative(s) of the first aspect of the invention and one or more pharmaceutically-acceptable excipients. Various embodiments and variants are provided.
摘要翻译：提供具有PPAR激动剂活性的衍生物。衍生物包括化合物和/或其药学上可接受的盐; 具有式（I）的化合物其中A具有结构（II）或（III）; X选自-CH 2 - ， - O - ， - N - 和-S-; Y选自-O - ， - NH-和-S-; 可以位于任何取代位置的Z是氢或卤素; R 1和R 2可以相同或不同，独立地选自氢和C 1 -C 8烷基，或者R 1和R 2一起形成具有4至6个碳原子的碳环; R 3选自氢和C 1 -C 8烷基; R 4，R 5，R 5和R 6可以相同或不同，独立地选自氢和C 1 C 8 -C 14烷基; 并且n为1至6.提供了各种实施方案和变体。根据其它方面，本发明还提供了在哺乳动物中产生PPARα激动剂活性的方法，所述方法包括向哺乳动物施用有效量的本发明第一方面的某些衍生物， PPARα激动剂活性和PPARα激动剂活性，所述方法包括向哺乳动物施用有效量的某些衍生物; 和包含本发明第一方面的衍生物和一种或多种药学上可接受的赋形剂的药物组合物。提供了各种实施例和变型。

6. 发明申请

WO2009019600A3 MODULATION OF ENDOGENOUS AMPK LEVELS FOR THE TREATMENT OF OBESITY 审中-公开
标题翻译：内源性AMPK水平的调节用于治疗肥胖
公开(公告)号：WO2009019600A3
公开(公告)日：2009-12-30
申请号：PCT/IB2008002140
申请日：2008-08-08
申请人： REDDYS LAB LTD DR , MISRA PARIMAL , CHAKRABARTI RANJAN , MADHURAREKHA CHINNABOINA , HASHAM SUMERA NIKHAT , POTLURI VIJAY KUMAR , SASMAL PRADIP KUMAR , DAS SAIBAL KUMAR , IQBAL JAVED
发明人： MISRA PARIMAL , CHAKRABARTI RANJAN , MADHURAREKHA CHINNABOINA , HASHAM SUMERA NIKHAT , POTLURI VIJAY KUMAR , SASMAL PRADIP KUMAR , DAS SAIBAL KUMAR , IQBAL JAVED
IPC分类号： G01N33/00
CPC分类号： C12Q1/485 , G01N2800/044
摘要： A method for identifying an AMPK activator is provided. The method includes providing a sample of cells that include AMPK and perilipin, providing a sample of an AMPK activator-candidate, contacting the cell sample and the activator-candidate, and measuring a quantitative indicator of the AMPK activation within the cell sample after the contacting step.
摘要翻译：提供了一种用于鉴定AMPK激活剂的方法。该方法包括提供包含AMPK和肾上腺素的细胞样品，提供AMPK激活剂候选物的样品，接触细胞样品和活化剂候选物，并测量接触后细胞样品中AMPK活化的定量指标步。

7. 发明申请

WO2007005785B1 THIAZOLES DERIVATIVES AS AMPK ACTIVATOR 审中-公开
标题翻译： THAZOLES衍生物作为AMPK激活剂
公开(公告)号：WO2007005785B1
公开(公告)日：2007-03-22
申请号：PCT/US2006025898
申请日：2006-06-30
申请人： REDDYS LAB LTD DR , REDDYS LAB INC DR , POTLURI VIJAY KUMAR , DAS SAIBAL KUMAR , SASMAL PRADIP KUMAR , IQBAL JAVED , MISRA PARIMAL , CHAKRABARTI RANJAN , TALWAR RASHMI
发明人： POTLURI VIJAY KUMAR , DAS SAIBAL KUMAR , SASMAL PRADIP KUMAR , IQBAL JAVED , MISRA PARIMAL , CHAKRABARTI RANJAN , TALWAR RASHMI
IPC分类号： C07D277/14 , A61K31/426 , A61K31/5377 , C07D265/32
CPC分类号： C07D277/42
摘要： The present application provides novel thiazole derivatives that are useful as activators of Adenosine 5'-Monophosphate-Activated Protein Kinase and pharmaceutical compositions containing such compounds.
摘要翻译：本申请提供了可用作腺苷5'-单磷酸激活蛋白激酶的激活剂的新型噻唑衍生物和含有这些化合物的药物组合物。

8. 发明申请

WO2012146980A3 PREPARATION OF FINGOLIMOD AND ITS SALTS 审中-公开
标题翻译：鱼类及其盐的制备
公开(公告)号：WO2012146980A3
公开(公告)日：2012-12-27
申请号：PCT/IB2012000922
申请日：2012-04-27
申请人： REDDYS LAB LTD DR , KATKAM SRINIVAS , SAGYAM RAJESWAR REDDY , MORTHALA RAGHAVENDAR RAO , IRENI BABU , VINIGARI KRISHNA , RAMDOSS SURESH KUMAR , RANGINENI SRINIVASULU , TUMMALA ARJUNKUMAR , IQBAL JAVED , ORUGANTI SRINIVAS , KANDAGATLA BHASKAR
发明人： KATKAM SRINIVAS , SAGYAM RAJESWAR REDDY , MORTHALA RAGHAVENDAR RAO , IRENI BABU , VINIGARI KRISHNA , RAMDOSS SURESH KUMAR , RANGINENI SRINIVASULU , TUMMALA ARJUNKUMAR , IQBAL JAVED , ORUGANTI SRINIVAS , KANDAGATLA BHASKAR
IPC分类号： C07C211/00 , C07D333/20
CPC分类号： C07C205/45 , C07C201/10 , C07C201/12 , C07C213/00 , C07C213/02 , C07C213/10 , C07C215/28 , C07C205/04
摘要： The present application provide processes for the preparation of fingolimod and its pharmaceutically acceptable salts, process for the purification of fingolimod hydrochloride and process for the preparation of amorphous fingolimod hydrochloride.
摘要翻译：本申请提供了芬戈莫德及其药学上可接受的盐的制备方法，盐酸芬戈莫德的纯化方法和用于制备无定形芬戈莫德盐酸盐的方法。

9. 发明申请

WO2004069145A2 NEW ANTICANCER COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM 审中-公开
标题翻译：新型化合物及其制备方法及含有它们的药物组合物
公开(公告)号：WO2004069145A2
公开(公告)日：2004-08-19
申请号：PCT/IB2004000299
申请日：2004-02-06
申请人： REDDYS LAB LTD DR , VEDULA MANOHAR SHARMA , KATTUBOINA VENKATA ADISESHU , IQBAL JAVED , RAMANUJAM RAJAGOPALAN , RAJAGOPAL SRIRAM , MAMIDI NAGA VENKATA SRINIVASA , JOSYULA RAMANATHAM , GUTTA MADHUSUDHAN
发明人： VEDULA MANOHAR SHARMA , KATTUBOINA VENKATA ADISESHU , IQBAL JAVED , RAMANUJAM RAJAGOPALAN , RAJAGOPAL SRIRAM , MAMIDI NAGA VENKATA SRINIVASA , JOSYULA RAMANATHAM , GUTTA MADHUSUDHAN
IPC分类号： A61K20060101 , C07D215/00 , C07D215/44 , C07D215/54 , C07D239/72 , C07D239/94 , A61K
CPC分类号： C07D239/94 , C07D215/44 , C07D215/54
摘要： The present invention relates to novel anticancer agents, their pharmaceutically acceptable salts, their geometrical isomers and their pharmaceutically acceptable compositions containing them. the present invention more particularly relates to novel quinazoline compounds, their pharmaceutically acceptable salts and their pharmaceutically acceptable compositions containing them. the novel quinazoline compounds have the general formula (I), where all symbols are as defined in the specification.
摘要翻译：本发明涉及新型抗癌剂，其药学上可接受的盐，它们的几何异构体及其含有它们的药学上可接受的组合物。本发明更具体地涉及新的喹唑啉化合物，其药学上可接受的盐及其含有它们的药学上可接受的组合物。新的喹唑啉化合物具有通式（I），其中所有符号如说明书中所定义。

10. 发明申请

WO2006029075A8 FIBRATE COMPOUNDS HAVING PPAR AGONIST ACTIVITY 审中-公开
标题翻译：具有PPAR激动剂活性的纤维化合物
公开(公告)号：WO2006029075A8
公开(公告)日：2007-04-26
申请号：PCT/US2005031532
申请日：2005-09-06
申请人： REDDYS LAB LTD DR , REDDYS LAB INC DR , DAS SAIBAL KUMAR , SINGH SUNIL KUMAR , MADHAVAN GURRAM RANGA , BHUNIYA DEBNATH , IQBAL JAVED , SHARMA SUDHIR KUMAR , CHAKRABARTI RANJAN
发明人： DAS SAIBAL KUMAR , SINGH SUNIL KUMAR , MADHAVAN GURRAM RANGA , BHUNIYA DEBNATH , IQBAL JAVED , SHARMA SUDHIR KUMAR , CHAKRABARTI RANJAN
IPC分类号： A61K31/519 , C07D487/02
CPC分类号： C07D487/04 , C07D239/90
摘要： There are provided derivatives having PPAR agonist activity. The derivatives include compounds and/or their pharmaceutically acceptable salts; the compounds having the formula (I) wherein A has the structure (II) or (III); X is chosen from -CH 2 -, -O-, -NH-, and -S-; Y is chosen from -O-, -NH-, and -S-; Z, which may be located in any position of substitution, is hydrogen or halogen; R 1 and R 2 , which may be the same or different, are independently chosen from hydrogen and C 1 -C 8 alkyl, or R 1 and R 2 together form a carbocyclic ring having from 4 to 6 carbon atoms; R 3 is chosen from hydrogen and C 1 -C 8 alkyl; R 4 , R 5 , and R 6 , which may be the same or different, are independently chosen from hydrogen and C 1 -C 8 alkyl; and n is 1 to 6. Various embodiments and variants are provided. In accordance with other aspects, the invention also provides methods of producing a PPARa agonist activity in a mammal, the methods including administering to the mammal an effective amount of certain derivative(s) of the first aspect of the invention, a method of producing a PPARa agonist activity and a PPARa agonist activity in a mammal, the method including administering to the mammal an effective amount of certain derivative(s); and a pharmaceutical composition that includes the derivative(s) of the first aspect of the invention and one or more pharmaceutically-acceptable excipients. Various embodiments and variants are provided.
摘要翻译：提供了具有PPAR激动剂活性的衍生物。衍生物包括化合物和/或其药学上可接受的盐; 其中A具有结构（II）或（III）的具有式（I）的化合物; X选自-CH 2 - ， - O - ， - NH-和-S-; Y选自-O - ， - NH-和-S-; 可以位于任何取代位置的Z是氢或卤素; R 1和R 2可以相同或不同，独立地选自氢和C 1 -C 8烷基，烷基或R 1和R 2一起形成具有4至6个碳原子的碳环; R 3选自氢和C 1 -C 8烷基; R 3选自氢和C 1 -C 8烷基; R 4，R 5和R 6可以相同或不同，独立地选自氢和C 1 -C 4烷基， -C 8烷基; 并且n是1至6.提供了各种实施例和变体。根据其它方面，本发明还提供了在哺乳动物中产生PPARα激动剂活性的方法，所述方法包括向哺乳动物施用有效量的本发明第一方面的某些衍生物，产生 PPARα激动剂活性和PPARα激动剂活性，所述方法包括给哺乳动物施用有效量的某些衍生物; 以及包含本发明第一方面的衍生物和一种或多种药学上可接受的赋形剂的药物组合物。提供了各种实施例和变体。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式