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1. 发明申请

WO02089901A2 METHOD AND APPARATUS FOR DETERMINING SPATIAL RELATION OF MULTIPLE IMPLANTABLE ELECTRODES 审中-公开
标题翻译：用于确定多个可植入电极的空间关系的方法和装置
公开(公告)号：WO02089901A2
公开(公告)日：2002-11-14
申请号：PCT/US0213152
申请日：2002-04-25
申请人： QUETZAL BIOMEDICAL INC
发明人： PRENTICE JOHN K , COSTELLO JIM , FUKA MARY Z
IPC分类号： A61N1/05 , A61N1/368 , A61N1/39 , A61N
CPC分类号： A61N1/3686 , A61N1/056 , A61N1/36185 , A61N1/3684 , A61N1/3956
摘要： An apparatus (100) and method to determine the relative locations of a set of implantable electrodes (E1-Ed), preferably five or more, which can be positioned in a chamber of the heart (18) or within another organ or chamber. At least two electrodes are configured to be a known distance from each other. A signal generation apparatus provides a signal having a frequency through a set of pairs of electrodes. This signal is detected on all other electrodes. Additional pairs of signal-emitting electrodes are selected and measurements are made on all other electrodes until sufficient sets of data have been acquired specify a set of equations. Solution of the sets of equations by numerical methods provides the relative locations of the electrodes in a dielectric medium. Where the electrodes are implanted in an environment comprising dielectric media of differing characteristics, such as blood and myocardial tissue, the signal generation apparatus is capable of producing signals at multiple frequencies. Sets of equations are acquired for multiple frequencies. Solutions of the equations derived from each of the sets of equations are combined to eliminate the effect of a non-uniform dielectric medium. Alternatively, the effect of differing media can be eliminated by calculating position vectors for image charges or virtual electrodes. Location of a dielectric boundary, such as the myocardial wall, may be determined.
摘要翻译：一种用于确定一组可植入电极（E1-Ed）的相对位置的装置（100）和方法，优选为五个或更多个，其可以位于心脏（18）的腔室中或在另一个器官或腔室内。至少两个电极被配置为彼此已知的距离。信号发生装置通过一组电极提供具有频率的信号。在所有其他电极上检测到该信号。选择附加的信号发射电极对，并且在所有其它电极上进行测量，直到获得足够的数据集来指定一组方程式。通过数值方法求解方程组提供电极在电介质中的相对位置。在电极被植入包括诸如血液和心肌组织等不同特征的电介质的环境中的情况下，信号发生装置能够产生多个频率的信号。针对多个频率采集一组方程式。将来自各组方程的方程的解组合起来以消除非均匀介电介质的影响。或者，可以通过计算图像电荷或虚拟电极的位置矢量来消除不同介质的影响。可以确定电介质边界的位置，例如心肌壁。

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