会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 1. 发明申请
    • CLEANING COMPOSITIONS CONTAINING MULTIPLY-SUBSTITUTED PROTEASE VARIANTS
    • 含有多取代蛋白质变体的清洁组合物
    • WO9920727A9
    • 1999-09-02
    • PCT/US9822588
    • 1998-10-23
    • PROCTER & GAMBLEGENENCOR INTGHOSH CHANCHAL KUMARBAECK ANDRE CESAROHTANI RYOHEIBUSCH ALFREDSHOWELL MICHAEL STANFORDSCHELLENBERGER VOLKERKELLIS JAMES T JRPAECH CHRISTIANNADHERNY JOANNENAKI DONALD PCOLLIER KATHERINE DCALDWELL ROBERT MPOULOSE AYROOKARAN J
    • GHOSH CHANCHAL KUMARBAECK ANDRE CESAROHTANI RYOHEIBUSCH ALFREDSHOWELL MICHAEL STANFORDSCHELLENBERGER VOLKERKELLIS JAMES T JRPAECH CHRISTIANNADHERNY JOANNENAKI DONALD PCOLLIER KATHERINE DCALDWELL ROBERT MPOULOSE AYROOKARAN J
    • A23G4/00A23G4/12A61K8/66A61Q11/00C11D1/74C11D3/37C11D3/386C12N9/54A23G3/30A61K7/28A61K7/48
    • A23G4/123A61K8/66A61Q11/00C11D1/74C11D3/3776C11D3/386C12N9/54C12Y304/21062
    • The present invention relates to cleaning compositions comprising a protease variant. One cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at an amino acid residue position corresponding to position 103 of Bacillus amyloliquefaciens subtilisin in combination with a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 1, 3, 4, 8, 9, 10, 12, 13, 16, 17, 18, 19, 20, 21, 22, 24, 27, 33, 37, 38, 42, 43, 48, 55, 57, 58, 61, 62, 68, 72, 75, 76, 77, 78, 79, 86, 87, 89, 97, 98, 99, 101, 102, 104, 106, 107, 109, 111, 114, 116, 117, 119, 121, 123, 126, 128, 130, 131, 133, 134, 137, 140, 141, 142, 146, 147, 158, 159, 160, 166, 167, 170, 173, 174, 177, 181, 182, 183, 184, 185, 188, 192, 194, 198, 203, 204, 205, 206, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 222, 224, 227, 228, 230, 232, 236, 237, 238, 240, 242, 243, 244, 245, 246, 247, 248, 249, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 265, 268, 269, 270, 271, 272, 274 and 275 of Bacillus amyloliquefaciens subtilisin; wherein when said protease variant includes a substitution of amino acid residues positions corresponding to positions 103 and 76, there is also a substitution of an amino acid residue at one or more amino acid residue positions other than amino acid residue positions corresponding to positions 27, 99, 101, 104, 107, 109, 123, 128, 166, 204, 206, 210, 216, 217, 218, 222, 260, 265 or 274 of Bacillus amyloliquefaciens subtilisin; and one or more cleaning adjunct materials. Another cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 62, 212, 230, 232, 252 and 257 of DOLLAR (Bacillus amyloliquefaciens) subtilisin; and one or more cleaning adjunct materials. Methods for using the cleaning compositions are also provided.
    • 本发明涉及包含蛋白酶变体的清洁组合物。 一种清洁组合物包含蛋白酶变体,其包括氨基酸残基与对应于解淀粉芽孢杆菌枯草杆菌蛋白酶的位置103的氨基酸残基处的另一个天然存在的氨基酸残基的取代,以及氨基酸残基与另一天然存在的 一个或多个对应于1,2,3,4,8,9,10,12,13,16,17,18,19,20,21,22,24,27,33, 37,38,42,43,48,55,57,58,61,62,68,72,75,76,77,78,79,86,87,89,97,98,99,101,102, 104,106,107,109,111,114,116,117,119,121,123,126,128,130,131,133,134,137,140,141,142,146, 160,166,167,170,173,174,177,181,182,183,184,185,188,192,194,198,203,204,205,206,209,210,211,212,213, 214,215,216,217,218,222,224,227,228,222,224,227,228,230,232,236,237,238,240,242,243,244,245,246,247,248,249,251,252,225,216,217,218,222,224,227,218,222,224,227,218,222,224,227,218,222,224,227,218,222,224,227,218,222,224,227,218,222,224 253,254,25 5,256,257,258,259,260,261,262,263,265,268,269,270,271,272,274和275的解淀粉芽孢杆菌枯草杆菌蛋白酶; 其中当所述蛋白酶变体包括对位置103和76的氨基酸残基置换时,还有一个或多个除对应于位置27,99的氨基酸残基位置之外的氨基酸残基的氨基酸残基的取代 ,解淀粉芽孢杆菌枯草杆菌蛋白酶的101,104,107,109,123,128,166,204,206,210,216,217,218,222,260,265或274; 和一种或多种清洁辅助材料。 另一种清洁组合物包含蛋白酶变体,其包括氨基酸残基与对应于DOLLAR(解淀粉芽孢杆菌)的位置62,212,230,232,252和257的一个或多个氨基酸残基处的另一个天然存在的氨基酸残基取代, 枯草杆菌蛋白酶; 以及一种或多种清洁辅助材料。 还提供了使用清洁组合物的方法。
    • 3. 发明申请
    • MULTIPLY-SUBSTITUTED PROTEASE VARIANT AND AMYLASE VARIANT-CONTAINING CLEANING COMPOSITIONS
    • 多种取代的蛋白质变体和淀粉含有变化的清洁组合物
    • WO9920723A9
    • 1999-09-02
    • PCT/US9822486
    • 1998-10-23
    • PROCTER & GAMBLEGHOSH CHANCHAL KUMARBAECK ANDRE CESAROHTANI RYOHEIBUSCH ALFREDSHOWELL MICHAEL STANTON
    • GHOSH CHANCHAL KUMARBAECK ANDRE CESAROHTANI RYOHEIBUSCH ALFREDSHOWELL MICHAEL STANTON
    • A23G4/00A23G4/12A23K1/165A61K8/00A61K8/25A61K8/36A61K8/37A61K8/40A61K8/41A61K8/44A61K8/46A61K8/60A61K8/64A61K8/66A61Q1/02A61Q1/14A61Q11/00A61Q11/02A61Q19/00A61Q19/10C11D3/386C11D3/395C11D7/42C12N1/15C12N1/19C12N1/21C12N5/10C12N9/50C12N9/54C12N9/56C12N9/58C12N15/09C12N15/57C12R1/07C11D
    • C12N9/54A23G4/123A23K20/189A61K8/66A61K2800/86A61Q11/00A61Q19/00C11D3/386C11D3/38609C11D3/38618C11D3/3907C11D3/3945C12Y304/00C12Y304/21062
    • The present invention relates to cleaning compositions comprising a protease variant. One cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at an amino acid residue position corresponding to position 103 of Bacillus amyloliquefaciens subtilisin in combination with a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 1, 3, 4, 8, 9, 10, 12, 13, 16, 17, 18, 19, 20, 21, 22, 24, 27, 33, 37, 38, 42, 43, 48, 55, 57, 58, 61, 62, 68, 72, 75, 76, 77, 78, 79, 86, 87, 89, 97, 98, 99, 101, 102, 104, 106, 107, 109, 111, 114, 116, 117, 119, 121, 123, 126, 128, 130, 131, 133, 134, 137, 140, 141, 142, 146, 147, 158, 159, 160, 166, 167, 170, 173, 174, 177, 181, 182, 183, 184, 185, 188, 192, 194, 198, 203, 204, 205, 206, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 222, 224, 227, 228, 230, 232, 236, 237, 238, 240, 242, 243, 244, 245, 246, 247, 248, 249, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 265, 268, 269, 270, 271, 272, 274 and 275 of Bacillus amyloliquefaciens subtilisin; wherein when said protease variant includes a substitution of amino acid residues at positions corresponding to positions 103 and 76, there is also a substitution of an amino acid residue at one or more amino acid residue positions other than amino acid residue positions corresponding to positions 27, 99, 101, 104, 107, 109, 123, 128, 166, 204, 206, 210, 216, 217, 218, 222, 260, 265 or 274 of Bacillus amyloliquefaciens subtilisin; and one or more cleaning adjunct materials. Another cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 62, 212, 230, 232, 252 and 257 of Bacillus amyloliquefaciens subtilisin; an amylase variant and one or more cleaning adjunct materials. Methods for using the cleaning compositions are also provided.
    • 本发明涉及包含蛋白酶变体的清洁组合物。 一种清洁组合物包含蛋白酶变体,其包括氨基酸残基与对应于解淀粉芽孢杆菌枯草杆菌蛋白酶的位置103的氨基酸残基处的另一个天然存在的氨基酸残基的取代,以及氨基酸残基与另一个天然存在的 在一个或多个对应于1,2,3,4,8,9,10,12,13,16,17,18,19,20,21,22,24,27,33, 37,38,42,43,48,55,57,58,61,62,68,72,75,76,77,78,79,86,87,89,97,98,99,101,102, 104,106,107,109,111,114,116,117,119,121,123,126,128,130,131,133,134,137,140,141,142,146,147, 160,166,167,170,173,174,177,181,182,183,184,185,188,192,194,188,203,204,205,206,209,210,211,212,213, 214,215,216,217,218,222,224,227,228,222,224,227,228,223,232,236,237,238,240,242,243,244,245,246,247,248,249,251,218,222,224,227,218,222,224,227,218,222,224,227,218,222,224,227,218,222,224,227,218,222,224,227,218,222,224,227,218,223,232 253,254,25 5,256,257,258,259,260,261,262,263,265,268,269,270,271,272,274和275的解淀粉芽孢杆菌枯草杆菌蛋白酶; 其中当所述蛋白酶变体包含氨基酸残基在对应于位置103和76的位置上的取代时,还存在氨基酸残基在一个或多个除对应于位置27的氨基酸残基位置之外的一个或多个氨基酸残基位置的取代, 99,101,104,107,109,123,128,166,204,206,210,216,217,218,222,260,265或274的解淀粉芽孢杆菌枯草杆菌蛋白酶; 和一种或多种清洁辅助材料。 另一种清洁组合物包含蛋白酶变体,其包括氨基酸残基与对应于解淀粉芽孢杆菌枯草杆菌蛋白酶的位置62,212,230,232,252和257的一个或多个氨基酸残基处的另一个天然存在的氨基酸残基取代; 淀粉酶变体和一种或多种清洁辅助材料。 还提供了使用清洁组合物的方法。