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1. 发明申请

WO2020181281A1 IMPLANT FOR CONTINUOUS PATIENT MONITORING AND INTELLIGENT TREATMENT 审中-公开
公开(公告)号：WO2020181281A1
公开(公告)日：2020-09-10
申请号：PCT/US2020/021710
申请日：2020-03-09
申请人： PROCEPT BIOROBOTICS CORPORATION , STAID, Kevin , MANTRI, Surag
发明人： STAID, Kevin , MANTRI, Surag , ALJURI, Nikolai
IPC分类号： A61B5/145 , A61F2/02 , A61N1/18
摘要： An implant with one or more sensors to measure fluid and tissues of the patient. The sensor may comprise a mechanical sensor configured to measure growth of a tissue such as BPH or a tumor. Alternatively or in combination, the implant may comprise one or more electrodes to stimulate tissue related to urinary urgency or male sexual function.

2. 发明申请

WO2022226103A1 SURGICAL PROBE WITH INDEPENDENT ENERGY SOURCES 审中-公开
公开(公告)号：WO2022226103A1
公开(公告)日：2022-10-27
申请号：PCT/US2022/025617
申请日：2022-04-20
申请人： PROCEPT BIOROBOTICS CORPORATION , MANTRI, Surag , STAID, Kevin Patrick , BADIA, James Luis , HO, Friedrich , TAYLOR, Scott D. , BENTLEY, Peter
发明人： MANTRI, Surag , STAID, Kevin Patrick , BADIA, James Luis , HO, Friedrich , TAYLOR, Scott D. , BENTLEY, Peter
IPC分类号： A61B17/32 , A61B17/3203 , A61B34/30
摘要： An energy source is offset from an elongate probe axis with an extension. The amount of offset of the energy source can be controlled by varying an amount of offset of the extension. The energy source rotated and translated at the offset distance to resect tissue. In some embodiments, the probe is configured to receive a second treatment probe comprising a second energy source, in which the second energy source is rotated and translated relative to the first treatment probe, which can improve positional accuracy and stability. The energy source and the extension can be coupled to a linkage to offset the energy source, and to translate and rotate the energy source with varying amounts of offset. The linkage can be coupled to a processor and one or more of the energy source moved in accordance with a treatment profile.

3. 发明申请

WO2017161331A1 MINIMALLY INVASIVE METHODS AND SYSTEMS FOR HEMOSTASIS IN A BLEEDING CLOSED TISSUE VOLUME 审中-公开
标题翻译：出血闭合组织体积中微创血栓形成的微创方法和系统
公开(公告)号：WO2017161331A1
公开(公告)日：2017-09-21
申请号：PCT/US2017/023062
申请日：2017-03-17
申请人： PROCEPT BIOROBOTICS CORPORATION
发明人： MANTRI, Surag , ALJURI, Nikolai , STAID, Kevin, Patrick , BADIA, James, Luis , BENTLEY, Peter , WANCHOO, Nishey
IPC分类号： A61F2/958 , A61F2/01 , A61M31/00 , A61M25/00 , A61M25/04 , A61M25/10
摘要： Disclosed herein are improved methods and apparatuses for providing hemostasis within a cavity defined by an internal surface of a bleeding tissue space. A catheter comprising a proximal end and a distal end may be advanced into the cavity through a proximal opening of the tissue space into the cavity. A distal balloon coupled to the catheter may be positioned adjacent a distal opening of the tissue space, and expanded to seal the distal opening. A hemostatic agent may be applied from the catheter to the internal surface of the tissue space to inhibit bleeding of the tissue space. The hemostatic agent may be applied without occluding the proximal opening, the distal opening, and a path extending therebetween with the hemostatic agent.
摘要翻译：本文公开了用于在由出血组织空间的内表面限定的腔内提供止血的改进的方法和设备。包括近端和远端的导管可以通过组织空间的近侧开口推进到腔中进入腔中。联接到导管的远端球囊可以定位在组织空间的远侧开口附近，并且扩张以密封远侧开口。止血剂可以从导管施加到组织空间的内表面以抑制组织空间的渗出。止血剂可以在不阻塞近端开口，远端开口以及用止血剂在其间延伸的路径的情况下施加。

4. 发明申请

WO2021263276A1 INTEGRATION OF ROBOTIC ARMS WITH SURGICAL PROBES 审中-公开
公开(公告)号：WO2021263276A1
公开(公告)日：2021-12-30
申请号：PCT/US2021/070760
申请日：2021-06-23
申请人： PROCEPT BIOROBOTICS CORPORATION
发明人： MANTRI, Surag , STAID, Kevin Patrick , ADAMS, David Vincent , HEMPHILL, Jason , HOANG, Jonathan Trung , SIRDESAI, Rishabh Mayur
IPC分类号： A61B34/30 , A61B17/28 , A61B17/29 , A61B34/00 , A61B34/20 , A61B34/37 , A61B1/00149 , A61B1/307 , A61B10/04 , A61B2034/2048 , A61B2034/2059 , A61B2034/301 , A61B2090/378 , A61B2560/0437 , A61B34/71 , A61B8/12 , A61B8/4218 , B25J15/0441 , B25J9/102
摘要： Embodiments of the present disclosure provide improved methods and apparatus for coupling a probe to an instrument device manipulator (e.g., robotic arm). In some embodiments, a probe, which may be carried by a handpiece, is configured to couple to the end of a device manipulator of a robotic arm. A transmission can be provided that is configured to couple to the probe and also couple to the instrument device manipulator. The transmission can be configured to receive motion input from the instrument device manipulator and transfer the motion input into motion of the probe. The transmission can provide improved movement of the probe. By decreasing the number of components on the handpiece and probe, the handpiece and probe can be provided as a sterile, single use consumable device and the transmission can be reused.

5. 发明申请

WO2016037132A1 GENE ANALYSIS AND GENERATION OF STEM CELL METHODS AND APPARATUS 审中-公开
标题翻译：干细胞方法和装置的基因分析和产生
公开(公告)号：WO2016037132A1
公开(公告)日：2016-03-10
申请号：PCT/US2015/048687
申请日：2015-09-04
申请人： PROCEPT BIOROBOTICS CORPORATION
发明人： ALJURI, Nikolai , MANTRI, Surag
IPC分类号： A61B10/02 , A61B10/04 , A61M1/00
CPC分类号： A61B10/02 , A61B10/0241 , A61B34/30 , A61B2017/00274 , A61B2017/32032 , A61B2217/005 , A61B2217/007 , G01N1/00
摘要： A surgical treatment apparatus comprises a waterjet configured to fragment tissue and provide intact cells such as stem cells with the fragmented tissue. The intact cells can be used in one or more of many ways such as for genetic or other testing, and the intact cells can be identified as stem cells. In many embodiments, the intact cells comprise stem cells. In many embodiments, a waterjet is configured to fragment tissue. The fragmented tissue can be collected with a filter having pores sized smaller than the tissue fragments. In many embodiments cavitation with a waterjet is used to fragment the tissue comprising the intact stem cells. The waterjet may comprise a waterjet immersed in a liquid comprising water so as to form a plurality of shedding pulses. The plurality of shedding pulses can be generated with a frequency sufficient to fragment the tissue. The shedding pulses can generate cavitations that fragment the tissue.
摘要翻译：手术治疗装置包括水射流，其被配置为将组织分离并且提供完整的细胞，例如具有碎片组织的干细胞。完整的细胞可以以许多方式中的一种或多种使用，例如用于遗传或其他测试，并且完整的细胞可以被鉴定为干细胞。在许多实施方案中，完整细胞包含干细胞。在许多实施例中，水射流被构造成分裂组织。可以用具有小于组织碎片的孔的过滤器收集碎片组织。在许多实施例中，使用水射流进行空化用于将包含完整干细胞的组织分裂。水射流可以包括浸入包含水的液体中的水射流，以形成多个脱落脉冲。可以以足以使组织分裂的频率产生多个脱落脉冲。脱落脉冲可以产生使组织碎裂的空化。

6. 发明申请

WO2015035249A2 AUTOMATED IMAGE-GUIDED TISSUE RESECTION AND TREATMENT 审中-公开
标题翻译：自动图像指导组织治疗和治疗
公开(公告)号：WO2015035249A2
公开(公告)日：2015-03-12
申请号：PCT/US2014/054412
申请日：2014-09-05
申请人： PROCEPT BIOROBOTICS CORPORATION
发明人： ALJURI, Nikolai , MANTRI, Surag , BAEZ, Luis , SURJAN, George , SASNETT, Michael, W. , FOOTE, Jonathan
IPC分类号： A61B18/12
CPC分类号： A61B8/085 , A61B8/12 , A61B17/3203 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/24 , A61B90/36 , A61B2017/00274 , A61B2018/00166 , A61B2018/00517 , A61B2018/00547 , A61B2018/00589 , A61B2018/00636 , A61B2018/00916 , A61B2018/00982 , A61B2018/00994 , A61B2018/1405 , A61B2018/141 , A61B2034/254 , A61B2218/001
摘要： A fluid stream is directed toward tissue to generate a plurality of shedding clouds. The fluid stream can be scanned such that the plurality of shedding clouds arrive a different overlapping locations. Each of the plurality of shedding clouds can remove a portion of the tissue. In many embodiments, an apparatus to ablate tissue comprises a source of pressurized fluid, and a nozzle coupled to the source of pressurized fluid to release a fluid stream, in which the fluid stream generates a plurality of shedding clouds.
摘要翻译：流体流被引向组织以产生多个脱落云。可以扫描流体流，使得多个脱落的云到达不同的重叠位置。多个脱落云中的每一个可以去除组织的一部分。在许多实施例中，用于烧蚀组织的装置包括加压流体源，以及连接到加压流体源以释放流体流的喷嘴，其中流体流产生多个脱落云。

7. 发明申请

WO2021262565A1 SYSTEMS AND METHODS FOR DEFINING AND MODIFYING RANGE OF MOTION OF PROBE USED IN PATIENT TREATMENT 审中-公开
公开(公告)号：WO2021262565A1
公开(公告)日：2021-12-30
申请号：PCT/US2021/038175
申请日：2021-06-21
申请人： PROCEPT BIOROBOTICS CORPORATION
发明人： MANTRI, Surag , STAID, Kevin Patrick , HEMPHILL, Jason , HUDELSON, Kevin Louis
IPC分类号： A61B5/05 , A61B2034/301 , A61B34/25 , A61B34/30 , A61B34/32 , A61B34/37 , A61B34/70 , A61B90/03 , A61B90/361 , A61B90/37 , B25J9/02 , B25J9/1664
摘要： A system for treating a target tissue of a patient comprises a first robotic arm coupled to a treatment probe for treating the target tissue of the patient, and a second robotic arm coupled to an imaging probe for imaging the target tissue of the patient. The system further comprises one or more computing devices operably coupled with the first robotic arm and the second robotic arm, the one or more computing devices configured to execute instructions for controlling movement of one or more of the first robotic arm or the second robotic arm. The treatment probe and/or imaging probe may be constrained to be moved only within an allowable range of motion.

8. 发明申请

WO2020181290A1 ROBOTIC ARMS AND METHODS FOR TISSUE RESECTION AND IMAGING 审中-公开
公开(公告)号：WO2020181290A1
公开(公告)日：2020-09-10
申请号：PCT/US2020/021756
申请日：2020-03-09
申请人： PROCEPT BIOROBOTICS CORPORATION
发明人： HEMPHILL, Jason , MANTRI, Surag , ALJURI, Nikolai , STAID, Kevin Patrick
IPC分类号： A61B34/30 , A61B8/00 , A61B8/12 , A61B34/00 , A61B90/00
摘要： A system for treating a target tissue of a patient comprises a first robotic arm coupled to a treatment probe for treating the target tissue of the patient, and a second robotic arm coupled to an imaging probe for imaging the target tissue of the patient. The system further comprises one or more computing devices operably coupled with the first robotic arm and the second robotic arm, the one or more computing devices configured to execute instructions for controlling movement of one or more of the first robotic arm or the second robotic arm.

9. 发明申请

WO2020181280A1 STIFF SHEATH FOR IMAGING PROBE 审中-公开
公开(公告)号：WO2020181280A1
公开(公告)日：2020-09-10
申请号：PCT/US2020/021708
申请日：2020-03-09
申请人： PROCEPT BIOROBOTICS CORPORATION
发明人： MANTRI, Surag , STAID, Kevin
IPC分类号： A61B1/015 , A61B1/00 , A61B1/01 , A61B1/012 , A61B1/12 , A61B1/313 , A61B8/12
摘要： An imaging probe is covered with a stiff sheath, which allows the imaging probe to move while the stiff sheath remains in a substantially fixed location for at least a portion of the surgical procedure while the probe moves within the stiff sheath. The stiff sheath may comprise sufficient stiffness to resist deformation as the imaging probe moves along an internal channel of the sheath. The sheath can be sized and shaped in many ways and may comprise one or more openings to allow fluid to move within the channel in which the probe is located.

10. 发明申请

WO2015200538A1 TISSUE SAMPLING AND CANCER TREATMENT METHODS AND APPARATUS 审中-公开
标题翻译：组织采样和癌症治疗方法和装置
公开(公告)号：WO2015200538A1
公开(公告)日：2015-12-30
申请号：PCT/US2015/037521
申请日：2015-06-24
申请人： PROCEPT BIOROBOTICS CORPORATION
发明人： ALJURI, Nikolai , PERKINS, Rodney , MANTRI, Surag
IPC分类号： A61M25/00 , A61M25/10
CPC分类号： A61B10/0283 , A61B10/0241 , A61B17/3203 , A61B17/32037 , A61B18/1492 , A61B2017/00274 , A61B2018/0022 , A61B2018/00547 , A61B2018/00595 , A61N5/1007 , A61N5/1015 , A61N5/1027 , A61N2005/1021 , A61N2005/1024 , A61N2005/1025
摘要： A catheter treatment apparatus comprises an elongate tubular member and an expandable support. The expandable support comprises a radioactive substance to treat cancerous tissue and is configured to expand from a narrow profile for insertion to a wide profile to engage and treat tissue remaining after resection. The expandable support can be sized to fit within a volume of removed tissue to place the radioactive substance in proximity to the capsule and remaining tissue, to spare the capsule and proximate nerves and vessels to treat tissue in proximity to the capsule. The elongate tubular member may comprise a channel such as a lumen to pass a bodily fluid such as urine when the expandable support engages the tissue to treat the patient for a plurality of days. The treatment apparatus can be used to resect and diagnose tissue concurrently. Based on the diagnosis, targeted segmental treatment may be given.
摘要翻译：导管治疗装置包括细长管状构件和可扩张支撑件。可扩张支架包括用于治疗癌性组织的放射性物质，并被构造成从狭窄的轮廓扩展到广泛的轮廓以接合和治疗切除后残留的组织。可膨胀支撑件的尺寸可以适合于移除的组织的体积以将放射性物质放置在胶囊和剩余组织附近，以便使胶囊和邻近的神经和血管以处理胶囊附近的组织。细长管状构件可以包括诸如内腔的通道，以在可膨胀支撑件与组织接合以治疗患者多天时通过诸如尿液的体液。治疗装置可用于同时切除和诊断组织。根据诊断，可以给予目标分期治疗。

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