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1. 发明申请

WO2011109106A2 IMMUNOGENIC COMPOSITIONS AGAINST HUMAN PROGASTRIN PEPTIDES 审中-公开
标题翻译：免疫组织化学反应人类孕激素
公开(公告)号：WO2011109106A2
公开(公告)日：2011-09-09
申请号：PCT/US2011000413
申请日：2011-03-03
申请人： ONKOLOGIX LTD , ASCIONE RICHARD , QI SHENGMEI , WANG BIN
发明人： ASCIONE RICHARD , QI SHENGMEI , WANG BIN
CPC分类号： A61K39/0005 , A61K47/646 , A61K47/65 , C07K14/595
摘要： Immunogens against human extended-progastrin species comprise (A) a mimetic peptide comprised of (i) the amino acid sequence of a progastrin or a N- and/or C-terminal processed species of a progastrin joined to (ii) a 7 amino-acid spacer coupled to (B) an immunogenic carrier. Illustrative of the mimetic peptide/spacer combination are a 21 amino-acid peptide (SEQ ID NO.: 1) and other, related polypeptides (SEQ ID NOs.: 2-5). Pharmaceutical compositions containing such an immunogen display improved immunological properties, including the induction of effective antibody levels shortly after the administration of an initial course of immunogen. Levels of antibody thus elicited stay elevated for several months and readily elevate to higher levels upon subsequent boosting by a single injection of immunogen.
摘要翻译：针对人类延伸的前胃泌素物种的免疫原包含（A）模仿肽，其包含（i）泌乳素或N-和/或C-末端加工物种的泌乳素的氨基酸序列，连接到（ii）与（B）免疫原性载体偶联的酸性间隔基。示例性的模拟肽/间隔物组合是21个氨基酸的肽（SEQ ID NO：1）和其它相关多肽（SEQ ID NO：2-5）。含有这种免疫原的药物组合物显示出改善的免疫学性质，包括在施用免疫原的初始过程之后不久诱导有效的抗体水平。因此引发的抗体水平保持升高几个月，并且通过单次注射免疫原随后升高时容易升高至较高水平。

2. 发明申请

WO2012019426A8 PHTHALAZINONE DERIVATIVE, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF 审中-公开
标题翻译：邻苯二酚衍生物及其制备方法及药物用途
公开(公告)号：WO2012019426A8
公开(公告)日：2012-05-10
申请号：PCT/CN2011001222
申请日：2011-07-26
申请人： SHANGHAI HENGRUI PHARM CO LTD , JIANGSU HENGRUI MEDICINE CO , TANG PENGCHO , LI XIN , WANG BIN , LI XIANGQIN , CHEN YANG , CHEN XUEJIANG , ZHANG LEI , SONG MIN
发明人： TANG PENGCHO , LI XIN , WANG BIN , LI XIANGQIN , CHEN YANG , CHEN XUEJIANG , ZHANG LEI , SONG MIN
IPC分类号： C07D471/04 , A61K31/502 , A61K31/506 , A61K31/519 , A61K31/5383 , A61P35/00 , C07D403/10 , C07D487/04 , C07D491/048 , C07D495/04 , C07D498/04 , C07D498/14
CPC分类号： C07D498/14 , C07D403/10 , C07D471/04 , C07D487/04 , C07D491/048 , C07D495/04 , C07D498/04
摘要： The present invention relates to a phthalazinone derivative, and a preparation method and a pharmaceutical use thereof, and specifically the present invention relates to a new phthalazinone derivative represented by a general formula (I), a preparation method, a pharmaceutical composition containing the derivative, and a use thereof as a therapeutic agent and especially a poly (ADP-ribose) polymerase (PARP) inhibitor.
摘要翻译：本发明涉及酞嗪酮衍生物及其制备方法和药物用途，具体涉及通式（I）表示的新的2,3-二氮杂萘酮衍生物，其制备方法，含有该衍生物的药物组合物，及其作为治疗剂，尤其是聚（ADP-核糖）聚合酶（PARP））抑制剂的用途。

3. 发明申请

WO2011137712A3 ANTENNA, TERMINAL, COMMUNICATION SYSTEM AND ASSETS MANAGEMENT METHOD 审中-公开
标题翻译：天线，终端，通信系统和资产管理方法
公开(公告)号：WO2011137712A3
公开(公告)日：2012-03-08
申请号：PCT/CN2011072824
申请日：2011-04-14
申请人： HUAWEI TECH CO LTD , CHEN YONGZHAN , WANG JISONG , WANG BIN , WAN LILONG
发明人： CHEN YONGZHAN , WANG JISONG , WANG BIN , WAN LILONG
IPC分类号： H04W24/00 , G06K17/00 , H01Q1/22
CPC分类号： H01Q1/22 , G06K2017/0051 , H01Q1/242
摘要： An antenna, terminal, communication system and assets management method are disclosed in the present invention which is belonging to the field of mobile communications. The antenna includes: an electronic tag device, wherein the electronic tag device is used for feeding back, when a detection command is received, antenna assets information stored locally to the terminal sending the detection command. The terminal includes a sending module and a receiving module. The communication system includes an antenna and a terminal matching with the antenna. The method includes: receiving a detection command, and according to the detection command, feeding back antenna assets information stored locally to the terminal sending the detection command. By using the electronic tag to feed back the antenna assets information to a demand side in the process of antenna assets management, the present invention can realize querying the antenna assets information in real time without visiting the station on the spot or checking the manual records, thus realizing informatization and real time of the antenna assets management, and reducing the risk of manual record errors.
摘要翻译：在本发明中公开了属于移动通信领域的天线，终端，通信系统和资产管理方法。天线包括：电子标签装置，其中当接收到检测命令时，电子标签装置用于反馈，天线资产信息本地存储在发送检测命令的终端。终端包括发送模块和接收模块。通信系统包括天线和与天线匹配的终端。该方法包括：接收检测命令，并根据检测命令将本地存储的天线资产信息反馈给发送检测命令的终端。通过使用电子标签在天线资产管理过程中将天线资产信息反馈给需求方，本发明可以实时地实时查询天线资产信息，而不是现场访问该站或者检查手动记录，从而实现天线资产管理的信息化和实时化，降低手动记录错误的风险。

4. 发明申请

WO2011038028A3 ENHANCED BLOCK REQUEST STREAMING USING BLOCK PARTITIONING OR REQUEST CONTROLS FOR IMPROVED CLIENT-SIDE HANDLING 审中-公开
标题翻译：使用分块分割或请求控制增强了块请求流，从而改进了客户端处理
公开(公告)号：WO2011038028A3
公开(公告)日：2011-10-06
申请号：PCT/US2010049862
申请日：2010-09-22
申请人： QUALCOMM INC , LUBY MICHAEL G , WATSON MARK , VICISANO LORENZO , PAKZAD PAYAM , WANG BIN
发明人： LUBY MICHAEL G , WATSON MARK , VICISANO LORENZO , PAKZAD PAYAM , WANG BIN
IPC分类号： H04L29/06 , H04N7/24
CPC分类号： H04L65/604 , H04L65/4084 , H04L65/602 , H04L65/607 , H04L65/80 , H04N21/23106 , H04N21/23406 , H04N21/234327 , H04N21/235 , H04N21/2401 , H04N21/25808 , H04N21/2662 , H04N21/435 , H04N21/44004 , H04N21/440227 , H04N21/44209 , H04N21/84 , H04N21/8456
摘要： A block request streaming system provides for improvements in the user experience and bandwidth efficiency of such systems, typically using an ingestion system that generates data in a form to be served by a conventional file server (HTTP, FTP, or the like), wherein the ingestion system intakes content and prepares it as files or data elements to be served by the file server. A client device can be adapted to take advantage of the ingestion process. The client device might be configured to optimize use of resources, given the information available to it from the ingestion system. This may include configurations to determine the sequence, timing and construction of block requests based on monitoring buffer size and rate of change of buffer size, use of variable sized requests, mapping of block requests to underlying transport connections, flexible pipelining of requests, and/or use of whole file requests based on statistical considerations.
摘要翻译：块请求流式传输系统通常使用产生由常规文件服务器（HTTP，FTP等）提供的形式的数据的摄取系统来改善这种系统的用户体验和带宽效率，其中，摄取系统摄取内容并将其准备为文件服务器要提供的文件或数据元素。可以调整客户端设备以利用摄取过程。考虑到从摄取系统可获得的信息，客户端设备可能被配置为优化资源的使用。这可以包括用于基于监视缓冲区大小和缓冲区大小的改变速率，可变大小的请求的使用，阻止请求到底层传输连接的映射，灵活流水线化请求和/或请求来确定阻止请求的顺序，时间和构造的配置，或基于统计考虑使用整个文件请求。

5. 发明申请

WO2008011090A3 METHOD OF SUBSALT VELOCITY ANALYSIS 审中-公开
标题翻译：方法分析速度分析
公开(公告)号：WO2008011090A3
公开(公告)日：2008-10-23
申请号：PCT/US2007016347
申请日：2007-07-19
申请人： CGG AMERICAS INC , WANG BIN , AUDEBERT FRANCOIS
发明人： WANG BIN , AUDEBERT FRANCOIS
IPC分类号： G01V1/28
CPC分类号： G01V1/303
摘要： A low-cost general method to perform subsalt velocity analysis is provided. For instances where sediment velocity structure is relatively simple, the method includes a single one-time redatuming to the base of salt, using existing prestack wave equation tools. For instances where the sediment velocity structure has a variable topography, the method includes multi-step redatuming to the base of salt. The method is designed to completely remove the salt-sediment overburden effects, and redatum the surface seismic data to a flat arbitrary subsalt datum, removing the complexity of the wavefield caused by the salt bodies. Once having obtained a simplified wavefield by stripping off the effects of the complex overburden, less expensive Kirchhoff imaging algorithms are employed for performing subsalt velocity model building.
摘要翻译：提供了一种执行子速度分析的低成本通用方法。对于泥沙速度结构相对简单的情况，该方法包括使用现有的叠前波方程工具对盐基进行单次一次性重绘。对于沉积物速度结构具有可变地形的情况，该方法包括多步地向盐底部进行重新排列。该方法旨在完全消除盐沉积物上覆层的影响，并将地表地震数据转化为平坦的任意盐点数据，消除盐体引起的波场复杂性。一旦通过剥离复杂覆盖层的影响获得了简化的波场，则采用较便宜的基尔霍夫成像算法来执行子速度模型建立。

6. 发明申请

WO2012122865A3 PHARMACEUTICALLY ACCEPTABLE SALT OF (E)-N-[4-[[3-CHLORO-4-(2-PYRIDYLMETHOXY)PHENYL]AMINO]-3-CYANO-7-ETHOXY-6-QUINOLYL]-3-[(2R)-1-METHYLPYRROLIDIN-2-YL]PROP-2-ENAMIDE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF 审中-公开
标题翻译：（E）-N- [4 - [[3-氯-4-（2-吡啶基甲基）苯基]氨基] -3-氰基-7-乙氧基-6-喹啉基〕-3 - 〔（2R） -1-甲基吡咯烷-2-基]丙-2-酮，其制备方法及其医疗用途
公开(公告)号：WO2012122865A3
公开(公告)日：2012-11-08
申请号：PCT/CN2012071015
申请日：2012-02-10
申请人： SHANGHAI HENGRUI PHARM CO LTD , JIANGSU HENGRUI MEDICINE CO , LI XIN , WANG BIN
发明人： LI XIN , WANG BIN
IPC分类号： C07D401/12 , A61K31/4709 , A61P35/00 , A61P43/00
CPC分类号： C07D401/14 , A61K31/4709 , C07C57/13 , C07C57/145 , C07C309/04 , C07C309/30
摘要： Provided as represented by formula (I) is a pharmaceutically acceptable salt of (E)-N-[4-[[3-chloro-4-(2-pyridylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolyl]-3-[(2R)-1-methylpyrrolidin-2-yl]prop-2-enamide, a preparation method therefor, and a use thereof as a therapeutic agent and especially as a protein kinase inhibitor.
摘要翻译：由式（I）表示的是（E）-N- [4 - [[3-氯-4-（2-吡啶基甲氧基）苯基]氨基] -3-氰基-7-乙氧基-6 - 喹啉基] -3 - [（2R）-1-甲基吡咯烷-2-基]丙-2-烯酰胺，其制备方法及其作为治疗剂，特别是作为蛋白激酶抑制剂的用途。

7. 发明申请

WO2009002792A3 REFLECTION-REPRESSED WIRE-GRID POLARIZER 审中-公开
标题翻译：反射回路电极偏振器
公开(公告)号：WO2009002792A3
公开(公告)日：2009-03-26
申请号：PCT/US2008067427
申请日：2008-06-19
申请人： MOXTEK INC , WANG BIN , GARDNER ERIC W , PERKINS RAYMOND T
发明人： WANG BIN , GARDNER ERIC W , PERKINS RAYMOND T
IPC分类号： G02B27/28 , G02B5/02 , G02B5/30
CPC分类号： G02B5/3058
摘要： A reflection repressed wire-grid polarizer (10a-e) for polarizing incident visible or infrared light (12) and selectively repressing a reflected polarization includes at least three layers (18a-d) disposed on a substrate (14). A polarizing wire-grid layer (18a) has an array of parallel metal wires (22) with a period less than half the wavelength of the incident light. A reflection-repressing layer or grid (18c) includes an inorganic and non-dielectric material which is optically absorptive of visible or infrared light, A dielectric layer or grid (18b, 18d) includes an inorganic and dielectric material.
摘要翻译：用于偏振入射的可见光或红外光（12）并选择性地抑制反射偏振的反射抑制线栅偏振器（10a-e）包括设置在基板（14）上的至少三层（18a-d）。极化线栅层（18a）具有平行金属线（22）的阵列，其周期小于入射光的波长的一半。反射抑制层或栅格（18c）包括光学吸收可见光或红外光的无机和非介电材料。电介质层或栅格（18b，18d）包括无机和电介质材料。

8. 发明申请

WO0132855A9 TRANSGENIC ANIMAL PRODUCTION USING LOPU-DERIVED OOCYTES 审中-公开
标题翻译：使用LOPU衍生的OOCYTES进行转基因动物生产
公开(公告)号：WO0132855A9
公开(公告)日：2001-09-27
申请号：PCT/US0029751
申请日：2000-10-27
申请人： NEXIA BIOTECH INC , BALDASSARRE HERNAN , KEEFER CAROL L , WANG BIN , KARATZAS COSTAS N
发明人： BALDASSARRE HERNAN , KEEFER CAROL L , WANG BIN , KARATZAS COSTAS N
IPC分类号： C12N15/873 , C12N15/00 , C12N5/00 , C12N15/09 , C12N15/63
CPC分类号： C12N15/873 , C12N2510/00
摘要： Methods for generating transgenic non-human animals using oocytes derived from laparoscopic ovum pick up.
摘要翻译：使用从腹腔镜卵子获取的卵母细胞产生转基因非人动物的方法。

9. 发明申请

WO2007049041A8 4- (3-AMINOPYRAZOLE) PYRIMIDINE DERIVATIVES FOR USE AS TYROSINE KINASE INHIBITORS IN THE TREATMENT OF CANCER 审中-公开
标题翻译：在治疗癌症中用作酪氨酸激酶抑制剂的4-（3-氨基吡唑）吡嗪衍生物
公开(公告)号：WO2007049041A8
公开(公告)日：2012-11-01
申请号：PCT/GB2006003978
申请日：2006-10-26
申请人： ASTRAZENECA AB , ASTRAZENECA UK LTD , FENG XIAOMEI , GUAN HUIPING , KAN YING , IOANNIDIS STEPHANOS , PENG BO , SU MEI , WANG BIN , WANG TAO , ZHANG HAI-JUN
发明人： FENG XIAOMEI , GUAN HUIPING , KAN YING , IOANNIDIS STEPHANOS , PENG BO , SU MEI , WANG BIN , WANG TAO , ZHANG HAI-JUN
IPC分类号： C07D403/14 , A61K31/506 , A61P35/00
CPC分类号： C07D403/14
摘要： This invention relates to novel compounds having the formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment for cancer.
摘要翻译：本发明涉及具有式（I）的新化合物及其药物组合物及其使用方法。这些新型化合物为癌症提供治疗。

10. 发明申请

WO2011038028A9 ENHANCED BLOCK REQUEST STREAMING USING BLOCK PARTITIONING OR REQUEST CONTROLS FOR IMPROVED CLIENT-SIDE HANDLING 审中-公开
公开(公告)号：WO2011038028A9
公开(公告)日：2011-05-19
申请号：PCT/US2010049862
申请日：2010-09-22
申请人： QUALCOMM INC , LUBY MICHAEL G , WATSON MARK , VICISANO LORENZO , PAKZAD PAYAM , WANG BIN
发明人： LUBY MICHAEL G , WATSON MARK , VICISANO LORENZO , PAKZAD PAYAM , WANG BIN
IPC分类号： H04L29/06
CPC分类号： H04L65/604 , H04L65/4084 , H04L65/602 , H04L65/607 , H04L65/80 , H04N21/23106 , H04N21/23406 , H04N21/234327 , H04N21/235 , H04N21/2401 , H04N21/25808 , H04N21/2662 , H04N21/435 , H04N21/44004 , H04N21/440227 , H04N21/44209 , H04N21/84 , H04N21/8456
摘要： A block request streaming system provides for improvements in the user experience and bandwidth efficiency of such systems, typically using an ingestion system that generates data in a form to be served by a conventional file server (HTTP, FTP, or the like), wherein the ingestion system intakes content and prepares it as files or data elements to be served by the file server. A client device can be adapted to take advantage of the ingestion process. The client device might be configured to optimize use of resources, given the information available to it from the ingestion system. This may include configurations to determine the sequence, timing and construction of block requests based on monitoring buffer size and rate of change of buffer size, use of variable sized requests, mapping of block requests to underlying transport connections, flexible pipelining of requests, and/or use of whole file requests based on statistical considerations.

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