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    • 7. 发明申请
    • PESTICIDES
    • 农药
    • WO1998017631A2
    • 1998-04-30
    • PCT/EP1997005857
    • 1997-10-23
    • NOVARTIS AGMÜLLER, Urs
    • NOVARTIS AG
    • C07C251/00
    • C07D213/643C07C251/60C07D231/12C07D233/56C07D239/34C07D249/08C07D277/28C07D277/32C07D307/81C07D417/04
    • The invention relates to novel pesticidally active compounds of formula (1) and to their possible isomers and mixtures of isomers, wherein: R1 is hydrogen, C1-C5alkyl, C3-C6alkenyl, C3-C6alkynyl, or Ar-C1-C5alkyl unsubstituted or substituted in the aryl moiety by halogen, C1-C5alkyl, C1-C5haloalkyl, C1-C5haloalkoxy or by cyano; R2 is C1-C5alkyl, C1-C3alkoxy-C1-C5alkyl, C3-C6alkenyl, C3-C6alkynyl, or Ar-C1-C5alkyl unsubstituted or substituted in the aryl moiety by halogen, C1-C5alkyl, C1-C5haloalkyl or by cyano; R3/R4 are each independently hydrogen, C1-C5alkyl or C1-C3alkoxy-C1-C5alkyl; A is a ketimino or aldimino group; and X is oxygen, NH or NR9 wherein R9 is hydrogen or C1-C5alkyl. The novel active ingredients have plant-protecting properties and are suitable for the protection of plants against infestation by phytopathogenic microorganisms.
    • 本发明涉及式(1)的新型杀虫活性化合物及其可能的异构体和异构体混合物,其中:R 1是氢,C 1 -C 5烷基,C 3 -C 6烯基,C 3 -C 6炔基或未取代或取代的Ar-C 1 -C 5烷基 在芳基部分由卤素,C 1 -C 5烷基,C 1 -C 5卤代烷基,C 1 -C 5卤代烷氧基或氰基取代; R 2是在芳基部分被卤素,C 1 -C 5烷基,C 1 -C 5卤代烷基或氰基取代的C 1 -C 5烷基,C 1 -C 3烷氧基-C 1 -C 5烷基,C 3 -C 6烯基,C 3 -C 6炔基或C 1 -C 5烷基。 R 3 / R 4各自独立地为氢,C 1 -C 5烷基或C 1 -C 3烷氧基-C 1 -C 5烷基; A是酮缩酮或阿霉素基; 并且X是氧,NH或NR 9,其中R 9是氢或C 1 -C 5烷基。 新型活性成分具有植物保护性质,适用于防止植物对植物病原微生物侵袭的侵害。
    • 10. 发明申请
    • TRANSGENIC PLANTS EXPRESSING CELLULOLYTIC ENZYMES
    • 表达微生物酶的转基因植物
    • WO1998011235A2
    • 1998-03-19
    • PCT/US1997016187
    • 1997-09-12
    • NOVARTIS AGLEBEL, EdouardHEIFETZ, PeterWARD, EricUKNES, Scott
    • NOVARTIS AG
    • C12N15/56
    • C12N15/8216C12N9/2437C12N15/8214C12N15/8217C12N15/8237C12N15/8238C12N15/8242C12N15/8246C12Y302/01004Y02E50/16Y02E50/17
    • The invention provides novel methods of controlling gene expression in plastids, using an inducible, transactivator-mediated system, and plants comprising the novel expression systems. The present invention further describes the production of cellulose-degrading enzymes in plants via the application of genetic engineering techniques. Cellulase coding sequences are fused to promoters active in plants and transformed into the nuclear genome and the chloroplast genome. As cellulases may be toxic to plants, preferred promoters are those that are chemically-inducible. In this manner, expression of the cellulase genes transformed into plants may be chemically induced at an appropriate time. In addition, the expressed cellulases may be targeted to vacuoles or other organelles to alleviate toxicity problems. The present invention finds utility in any industrial process requiring a plentiful supply of cellulases, but particularly finds utility in the conversion of cellulosic biomass to ethanol.
    • 本发明提供了使用诱导型反式激活因子介导的系统以及包含新型表达系统的植物来控制质体中基因表达的新方法。 本发明进一步描述了通过应用基因工程技术在植物中生产纤维素降解酶。 纤维素酶编码序列与在植物中有活性的启动子融合,并转化到核基因组和叶绿体基因组中。 由于纤维素酶对植物有毒性,优选的启动子是化学诱导型的启动子。 以这种方式,可以在适当的时间化学诱导转化到植物中的纤维素酶基因的表达。 此外,表达的纤维素酶可以靶向液泡或其他细胞器以减轻毒性问题。 本发明可用于需要大量供应纤维素酶的任何工业过程中,特别是在纤维素生物质转化为乙醇方面具有实用价值。