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1. 发明申请

WO2008150068A1 MEDICINAL HERBAL EXTRACT HAVING ANTI-OBESITY EFFECT 审中-公开
标题翻译：具有抗焦虑作用的药用草药提取物
公开(公告)号：WO2008150068A1
公开(公告)日：2008-12-11
申请号：PCT/KR2008/002584
申请日：2008-05-08
申请人： NEWGEX INC. , SEO, Jong-Bae , CHOI, Sun-Mi , CHOI, Eun-Jung , PARK, Sang-Wook , CHOI, Eun-Wook , SEEN, Dong-Seung , LEE, Tae-Gyu
发明人： SEO, Jong-Bae , CHOI, Sun-Mi , CHOI, Eun-Jung , PARK, Sang-Wook , CHOI, Eun-Wook , SEEN, Dong-Seung , LEE, Tae-Gyu
IPC分类号： A61K36/185
CPC分类号： A61K36/185 , A61K9/0019 , A61K9/08 , A61K9/2059 , A61K9/4866
摘要： Disclosed is an anti-obesity active extract obtained from a medicinal plant. More specifically, the extract obtained from lysimachiae f oenum-graeci herba (which is a medicinal plant traditionally used in the East) can be used as an active ingredient for a raw material, a functional food, cosmetic, a crude drug, etc. for an obesity preventing or therapeutic agent because the extract can suppress the adipocyte differentiation and decrease the body weight and body fat in an obese animal, thereby suppressing fat accumulation (that is, a factor for obesity).
摘要翻译：公开了从药用植物获得的抗肥胖活性提取物。更具体地说，可以将从赖氏植物得到的提取物（其是东方传统使用的药用植物）可用作原料，功能性食品，化妆品，生药等的活性成分，用于因为提取物能够抑制肥胖动物的脂肪细胞分化和降低体重和体脂肪，从而抑制脂肪蓄积（即，肥胖的因素）。

2. 发明申请

WO2009084875A3 COMPOSITION FOR PREVENTING AND TREATING METABOLIC DISEASES COMPRISING THE EXTRACT OF LYSIMACHIAE FOENUM-GRAECI HERBA 审中-公开
公开(公告)号：WO2009084875A3
公开(公告)日：2009-07-09
申请号：PCT/KR2008/007706
申请日：2008-12-26
申请人： NEWGEX INC. , SEO, Jong-Bae , PARK, Jae-Young , CHOI, Sun-Mi , PARK, Sang-Wook , CHOE, Sung-Sik , CHOI, Eun-Wook , SEEN, Dong-Seung , LEE, Tae-Gyu
发明人： SEO, Jong-Bae , PARK, Jae-Young , CHOI, Sun-Mi , PARK, Sang-Wook , CHOE, Sung-Sik , CHOI, Eun-Wook , SEEN, Dong-Seung , LEE, Tae-Gyu
IPC分类号： A61K36/185
摘要： Disclosed are raw material, functional foods, and herb medicines for preventing and treating metabolic diseases, which comprise a Lysimachiae Foenum-Graeci Herba extract as an effective ingredient. The Lysimachiae Foenum-Graeci Herba extract have an activity of reducing blood glucose levels, triglycerides and cholesterol levels, AST and ALT levels, and fat in the liver, and thus can be effectively used as a hepatic protector and a remedy for preventing and treating various metabolic diseases including diabetes, high blood pressure, fatty liver, cardiovascular diseases, and hyperlipidemia.

3. 发明申请

WO2008093902A1 MEDICINAL PLANT EXTRACTS ACTING AS BETA2 AGONIST FOR ASTHMA TREATMENT 审中-公开
标题翻译：作为用于ASTHMA治疗的BETA2激动剂的药物植物提取物
公开(公告)号：WO2008093902A1
公开(公告)日：2008-08-07
申请号：PCT/KR2007/000523
申请日：2007-01-31
申请人： NEUROGENEX CO., LTD. , CHOI, Eun-Wook , LEE, Dong-Seok , LEE, Tae-Gyu , SEEN, Dong-Seung , PARK, Sang-Wook , CHOI, Eun-Jung
发明人： CHOI, Eun-Wook , LEE, Dong-Seok , LEE, Tae-Gyu , SEEN, Dong-Seung , PARK, Sang-Wook , CHOI, Eun-Jung
IPC分类号： A61K36/47 , A61K36/23 , A61K36/714 , A61K36/83 , A61K36/39 , A23L1/29 , A61P11/06 , A61P11/08
CPC分类号： A61K36/23 , A23L33/105 , A23V2002/00 , A61K36/47 , A61K36/714 , A61K36/83 , A23V2200/314 , A23V2250/21
摘要： The present invention relates to medicinal plant extracts acting as β2 receptor agonist. More specifically, this invention relates to extracts from one or more medicinal plants or parts of the plants, such as Euphorbiae kansui, Anthriscus sylvestris, Croton Tiglium, Aconitum carmichaeli, Daphne genkwa, Calystegia soldanellan and Sapium japonicum, wherein the extracts enhance β2 receptor activity and relieve airway contraction of an asthmatic patient. This invention also relates to a method of extracting medicinal plant constituents more efficiently, and relates to raw materials, functional foods or natural product medicines, which contain the medicinal plant extracts, for preventing and treating asthma.
摘要翻译：本发明涉及用作β2受体激动剂的药用植物提取物。更具体地，本发明涉及来自一种或多种药用植物或植物部分的提取物，例如大戟科，蓟马蓟马，巴豆ium，乌头乌头，达芙妮genkwa，卡桑半胱氨酸和日本札幌，其中提取物增强β2受体活性并减轻哮喘患者的气道收缩。本发明还涉及更有效地提取药用植物成分的方法，涉及含有用于预防和治疗哮喘的药用植物提取物的原料，功能性食品或天然产物药物。

4. 发明申请

WO2005053378A1 DEVICE FOR RAISING SEEDLINGS 审中-公开
标题翻译：提高种子的装置
公开(公告)号：WO2005053378A1
公开(公告)日：2005-06-16
申请号：PCT/KR2004/003133
申请日：2004-12-01
申请人： NAM JIN AGRICULTURE TECHNIQUE LTD. , PARK, Sang-Wook , YOO, Nam-Jin , PARK, Sung-Tae
发明人： PARK, Sang-Wook , YOO, Nam-Jin , PARK, Sung-Tae
IPC分类号： A01G9/02
CPC分类号： A01G31/06 , Y02P60/216
摘要： The present invention discloses a device for raising seedlings, which is convenient to use and by use thereof manufacturing costs can be reduced and processing procedure can be simplified. The device for raising seedlings has a plurality of pole members standing in parallel. A plurality of tray members disposed in parallel between the plurality of pole members include at least one partition therein. A plurality of boxes for raising seedlings are disposed between the partitions of the tray members to raise young rice plants and include a plurality of through holes in the bottom surface thereof. A water supplying part is mounted onto a plurality of pole members to supply water into the boxes for raising seedlings. A warm air supplying part is disposed around the pole members and the tray members to supply warm air into the boxes for raising seedlings.
摘要翻译：本发明公开了一种用于育苗的装置，其使用方便，并且通过使用可以减少制造成本，并且可以简化处理程序。育苗装置具有平行站立的多个杆件。并列设置在多个极构件之间的多个托盘构件包括至少一个分隔件。多个用于培育幼苗的盒子设置在托盘构件的隔板之间，以提升幼米，并在其底面包括多个通孔。供水部件安装在多个杆件上，以将水供入到用于养殖幼苗的箱中。热空气供应部分设置在极构件和托盘构件周围，以将暖空气供应到用于养殖幼苗的箱中。

5. 发明申请

WO2011025179A2 METHOD OF INDUCING THE DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS INTO MESENCHYMAL STEM CELLS 审中-公开
标题翻译：诱导人胚胎干细胞分化为间质干细胞的方法
公开(公告)号：WO2011025179A2
公开(公告)日：2011-03-03
申请号：PCT/KR2010/005471
申请日：2010-08-18
申请人： KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY , HAN, Yong-Mahn , TUNG, Tran-Ngoc , PARK, Sang-Wook , JANG, Mi-jin
发明人： HAN, Yong-Mahn , TUNG, Tran-Ngoc , PARK, Sang-Wook , JANG, Mi-jin
IPC分类号： C12N5/00 , C12N7/00
CPC分类号： C12N5/0606 , C12N5/0662 , C12N2501/115 , C12N2501/155 , C12N2501/16 , C12N2501/415 , C12N2501/999 , C12N2506/02
摘要： Disclosed is a method for inducing human embryonic stem cells to differentiate into mesenchymal stem cells, using an optimal medium. Human embryonic stem cells are induced differentiate into mesodermal progenitors by activating TGF-β (Transforming growth factor-β), WNT and BMP (Bone morphogenic protein) signaling pathways and further into mesenchymal stem cells by treating with bFGF. The method is effective for producing mesenchymal stem cells, useful cell-based therapies, on a large scale.
摘要翻译：公开了使用最佳培养基诱导人胚胎干细胞分化为间充质干细胞的方法。通过激活TGF-β（转化生长因子-β），WNT和BMP（骨形态发生蛋白）信号传导途径并通过用bFGF处理进一步进入间充质干细胞，诱导人胚胎干细胞分化成中胚层祖细胞。该方法对于大规模生产间充质干细胞是有效的基于细胞的疗法是有效的。

6. 发明申请

WO2009104825A1 METHOD FOR INDUCING THE DEFFERENTIATION OF EMBRYONIC STEM CELLS INTO HEMANGIOBLAST 审中-公开
标题翻译：诱导胚胎干细胞分化为HEMANGIOBLAST的方法
公开(公告)号：WO2009104825A1
公开(公告)日：2009-08-27
申请号：PCT/KR2008/000952
申请日：2008-02-18
申请人： KAIST , HAN, Yong-Mahn , PARK, Sang-Wook , LEE, Eun-Young
发明人： HAN, Yong-Mahn , PARK, Sang-Wook , LEE, Eun-Young
IPC分类号： C12N5/08 , C12N5/02
CPC分类号： C12N5/069 , C12N5/0647 , C12N5/0691 , C12N5/0692 , C12N2501/115 , C12N2501/155 , C12N2501/165 , C12N2501/999 , C12N2506/02 , C12N2506/28
摘要： The present invention relates to a composition for inducing embryonic stem cell differentiation comprising a MEK/ERK (mitogen-activated protein kinase kinase/extracellular regulated kinase) signal transduction inhibitor and BMP (bone morphogenetic protein), and a method for inducing differentiation of embryonic stem cells into mesodermal cells using the same. Further, the mesodermal cells obtained by the above method are able to differentiate into various mesenchymal tissue cells. In particular, the present invention relates to a method for inducing differentiation into hemangioblast by culturing the mesodermal cells obtained by the above method in the presence of VEGF (vascular endothelial cell growth factor) and bFGF (basic fibroblast growth factor). The differentiated hemangioblasts can be further differentiated into vascular endothelial cells, vascular smooth muscle cells, and hematopoietic stem cells under various culture conditions.
摘要翻译：本发明涉及一种用于诱导胚胎干细胞分化的组合物，其包含MEK / ERK（丝裂原活化蛋白激酶激酶/细胞外调节激酶）信号转导抑制剂和BMP（骨形态发生蛋白）），以及诱导胚胎干细胞分化的方法细胞使用相同的细胞进入中胚层细胞。此外，通过上述方法获得的中胚层细胞能够分化成各种间充质组织细胞。特别地，本发明涉及通过在VEGF（血管内皮细胞生长因子）和bFGF（碱性成纤维细胞生长因子）的存在下培养通过上述方法获得的中胚层细胞，诱导分化成成血管细胞的方法。分化的成血管细胞可以在各种培养条件下进一步分化成血管内皮细胞，血管平滑肌细胞和造血干细胞。

7. 发明申请

WO2005051941A1 THIONE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 审中-公开
标题翻译：其衍生物，其制备方法和含有该衍生物的药物组合物
公开(公告)号：WO2005051941A1
公开(公告)日：2005-06-09
申请号：PCT/KR2003/002553
申请日：2003-11-25
申请人： CJ CORPORATION , CHO, Il-Hwan , CHAE, Myeong-Yun , KIM, Young-Hoon , YEON, Kyu-Jeong , LYU, Chun-Seon , KIM, Jong-Hoon , JUNG, Sung-Hak , PARK, Sang-Wook , RYU, Hyung-Chul , NOH, Ji-Young , PARK, Hyun-Jung , PARK, Jie-Eun , CHUNG, Young-Mee
发明人： CHO, Il-Hwan , CHAE, Myeong-Yun , KIM, Young-Hoon , YEON, Kyu-Jeong , LYU, Chun-Seon , KIM, Jong-Hoon , JUNG, Sung-Hak , PARK, Sang-Wook , RYU, Hyung-Chul , NOH, Ji-Young , PARK, Hyun-Jung , PARK, Jie-Eun , CHUNG, Young-Mee
IPC分类号： C07D339/04
CPC分类号： C07D231/18 , C07C317/44 , C07D213/55 , C07D339/04 , C07D409/04
摘要： A 1,2,4-triazole derivative of formula (1) or a non-toxic salt thereof, a preparation method thereof, and a pharmaceutical composition containing the derivative or the salt as an active ingredient are provided.
摘要翻译：提供式（1）的1,2,4-三唑衍生物或其无毒盐，其制备方法和含有该衍生物或盐作为有效成分的药物组合物。

8. 发明申请

WO2004048347A1 1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME 审中-公开
标题翻译： 1,2,4-三唑衍生物，其制备方法和含有该衍生物的药物组合物
公开(公告)号：WO2004048347A1
公开(公告)日：2004-06-10
申请号：PCT/KR2003/002574
申请日：2003-11-26
申请人： CJ CORPORATION , CHO, Il-Hwan , KO, Dong-Hyun , CHAE, Myeong-Yun , MIN, In-Ki , KIM, Young-Hoon , YEON, Kyu-Jeong , KIM, Jong-Hoon , JUNG, Sung-Hak , PARK, Sang-Wook , KIM, Il-Hwan , RYU, Hyung-Chul , NOH, Ji-Young , PARK, Hyun-Jung , PARK, Jie-Eun , CHUNG, Young-Mee
发明人： CHO, Il-Hwan , KO, Dong-Hyun , CHAE, Myeong-Yun , MIN, In-Ki , KIM, Young-Hoon , YEON, Kyu-Jeong , KIM, Jong-Hoon , JUNG, Sung-Hak , PARK, Sang-Wook , KIM, Il-Hwan , RYU, Hyung-Chul , NOH, Ji-Young , PARK, Hyun-Jung , PARK, Jie-Eun , CHUNG, Young-Mee
IPC分类号： C07D249/12
CPC分类号： C07D249/12 , C07D249/10
摘要： A 1,2,4-triazole derivative of formula 1 or a non-toxic salt thereof, a preparation method thereof, and a pharmaceutical composition containing the derivative or the salt as an active ingredient are provided.
摘要翻译：提供式1的1,2,4-三唑衍生物或其无毒盐，其制备方法和含有该衍生物或盐作为有效成分的药物组合物。

9. 发明申请

WO2003055874A1 BIPYRIDINYL DERIVATIVES AS A HIGHLY SELECTIVE CYCLOOXYGENASE-2 INHIBITOR 审中-公开
标题翻译： BIPYRIDINYL衍生物作为高选择性CYCLOOXYGENASE-2抑制剂
公开(公告)号：WO2003055874A1
公开(公告)日：2003-07-10
申请号：PCT/KR2002/002446
申请日：2002-12-27
申请人： CJ CORP. , CHO, Il-Hwan , LIM, Jee-Woong , NOH, Ji-Young , KIM, Jong-Hoon , PARK, Sang-Wook , RYU, Hyung-Chul , KIM, Je-Hak , KIM, Jong-Ho , WANG, So-Young , KIM, Dal-Hyun
发明人： CHO, Il-Hwan , LIM, Jee-Woong , NOH, Ji-Young , KIM, Jong-Hoon , PARK, Sang-Wook , RYU, Hyung-Chul , KIM, Je-Hak , KIM, Jong-Ho , WANG, So-Young , KIM, Dal-Hyun
IPC分类号： C07D401/02
CPC分类号： C07D213/71
摘要： The present invention relates to a novel bipyridinyl derivative having a structure of formula (1) and its pharmaceutically acceptable salts, optical isomer and method for preparing it as a highly selective cyclooxygenase-2 inhibitor, wherein R is defined in this specification
摘要翻译：本发明涉及具有式（1）结构的新型联吡啶衍生物及其药学上可接受的盐，旋光异构体及其制备为高选择性环氧合酶-2抑制剂的方法，其中R在本说明书中定义

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