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1. 发明申请

WO2009104825A1 METHOD FOR INDUCING THE DEFFERENTIATION OF EMBRYONIC STEM CELLS INTO HEMANGIOBLAST 审中-公开
标题翻译：诱导胚胎干细胞分化为HEMANGIOBLAST的方法
公开(公告)号：WO2009104825A1
公开(公告)日：2009-08-27
申请号：PCT/KR2008/000952
申请日：2008-02-18
申请人： KAIST , HAN, Yong-Mahn , PARK, Sang-Wook , LEE, Eun-Young
发明人： HAN, Yong-Mahn , PARK, Sang-Wook , LEE, Eun-Young
IPC分类号： C12N5/08 , C12N5/02
CPC分类号： C12N5/069 , C12N5/0647 , C12N5/0691 , C12N5/0692 , C12N2501/115 , C12N2501/155 , C12N2501/165 , C12N2501/999 , C12N2506/02 , C12N2506/28
摘要： The present invention relates to a composition for inducing embryonic stem cell differentiation comprising a MEK/ERK (mitogen-activated protein kinase kinase/extracellular regulated kinase) signal transduction inhibitor and BMP (bone morphogenetic protein), and a method for inducing differentiation of embryonic stem cells into mesodermal cells using the same. Further, the mesodermal cells obtained by the above method are able to differentiate into various mesenchymal tissue cells. In particular, the present invention relates to a method for inducing differentiation into hemangioblast by culturing the mesodermal cells obtained by the above method in the presence of VEGF (vascular endothelial cell growth factor) and bFGF (basic fibroblast growth factor). The differentiated hemangioblasts can be further differentiated into vascular endothelial cells, vascular smooth muscle cells, and hematopoietic stem cells under various culture conditions.
摘要翻译：本发明涉及一种用于诱导胚胎干细胞分化的组合物，其包含MEK / ERK（丝裂原活化蛋白激酶激酶/细胞外调节激酶）信号转导抑制剂和BMP（骨形态发生蛋白）），以及诱导胚胎干细胞分化的方法细胞使用相同的细胞进入中胚层细胞。此外，通过上述方法获得的中胚层细胞能够分化成各种间充质组织细胞。特别地，本发明涉及通过在VEGF（血管内皮细胞生长因子）和bFGF（碱性成纤维细胞生长因子）的存在下培养通过上述方法获得的中胚层细胞，诱导分化成成血管细胞的方法。分化的成血管细胞可以在各种培养条件下进一步分化成血管内皮细胞，血管平滑肌细胞和造血干细胞。

2. 发明申请

WO2002082008A1 A METHOD AND APPARATUS OF TWO WAVELENGTH INTERFEROMETRY FOR MEASURING ACCURATE HEIGHT OF SMALL STEP COMPOSED OF TWO DIFFERENT MATERIALS 审中-公开
标题翻译：用于测量由两种不同材料组成的小步骤的精确高度的两个波长干涉测量方法和装置
公开(公告)号：WO2002082008A1
公开(公告)日：2002-10-17
申请号：PCT/KR2002/000609
申请日：2002-04-08
申请人： KAIST , KIM, Seung-Woo , PARK, Min-Cheol
发明人： KIM, Seung-Woo , PARK, Min-Cheol
IPC分类号： G01B9/02
CPC分类号： G01B11/0608 , G01B9/02007 , G01B9/02057 , G01B9/02084 , G01B9/0209
摘要： This invention is on a measurement method and apparatus for measuring the accurate height of a very small step composed of two different flat materials. In this method, two wavelength-white light interferometry is used and the measuring error caused by the change in phase difference by two materials is compensated by a unique equation.
摘要翻译：本发明是用于测量由两种不同平板材料组成的非常小的台阶的精确高度的测量方法和装置。在这种方法中，使用两种波长 - 白光干涉测量法，由两种材料的相位差变化引起的测量误差由一个独特的方程补偿。

3. 发明申请

WO2007043731A1 METHOD OF THE PREPARATION OF MICROPOROUS CRYSTALLINE MOLECULAR SIEVE POSSESSING MESOPOROUS FRAMEWORKS 审中-公开
标题翻译：微孔结构分子筛制备多孔骨架的方法
公开(公告)号：WO2007043731A1
公开(公告)日：2007-04-19
申请号：PCT/KR2006/000720
申请日：2006-03-02
申请人： KAIST , RYOO, Ryong , CHOI, Minkee
发明人： RYOO, Ryong , CHOI, Minkee
IPC分类号： C01B33/14
CPC分类号： C01B39/40 , B01J29/40 , B01J29/83 , B01J29/89 , B01J35/1061 , B01J2229/64 , C01B37/005 , C01B37/02 , C01B39/04 , C01B39/145 , C01B39/265 , C01B39/48 , C01B39/54
摘要： The present invention relates to a method of preparing a microporous crystalline molecular sieve having mesoporous skeleton, comprising following steps: (a) adding a meso-SDA (meso-Structure Directing Agent) into a gel composition of synthesizing molecular sieve, (b) subjecting the mixture obtained in the above step (a) to crystallization by a hydrothermal reaction, a microwave reaction, a dry-gel synthesis, etc., and (c) removing selectively organic materials from the resulted material obtained in the above step (b) by a calcination or a chemical treatment. Molecular sieve having mesoporous skeleton synthesized by the present invention exhibits, as compared with conventional zeolite, a good molecule diffusion ability and a greatly improved catalytic activity.
摘要翻译：本发明涉及一种制备具有介孔骨架的微孔结晶分子筛的方法，包括以下步骤：（a）将内消旋-SSD（内消旋结构定向剂）加入合成分子筛的凝胶组合物中，（b）在上述步骤（a）中获得的混合物通过水热反应，微波反应，干凝胶合成等结晶，和（c）从上述步骤（b）中获得的所得材料中选择性地除去有机材料，通过煅烧或化学处理。通过本发明合成的具有中孔骨架的分子筛，与现有的沸石相比，具有良好的分子扩散能力和大大提高的催化活性。

4. 发明申请

WO2002096564A1 METHOD AND DEVICE FOR STABILIZING LENGTH OF ENGINEERING MATERIAL USING THERMOPHYSICAL CHARACTERISTIC OF GALLIUM 审中-公开
标题翻译：使用GALLIUM的热物理特性来稳定工程材料的长度的方法和装置
公开(公告)号：WO2002096564A1
公开(公告)日：2002-12-05
申请号：PCT/KR2002/000954
申请日：2002-05-21
申请人： KAIST , KIM, Seung-Woo , KEEM, Taeho
发明人： KIM, Seung-Woo , KEEM, Taeho
IPC分类号： B01L11/00
CPC分类号： B01L7/00
摘要： Disclosed are a device and a method for making an experiment on temperature characteristic of material. The device includes a small volume thermostat for maintaining temperature uniformly and an interferometer for measuring a length change according to a temperature change of a measured fragment. Material, which maintains inside temperature of the thermostat uniformly, is disposed around the thermostat. The material maintains temperature uniformly for a long time when phase is changed. A hole is formed in a front surface of the thermostat to allow beam to be transmitted, thereby measuring the length change of the measured fragment inside the thermostat. By measuring the length change in a noncontact way when beam is transmitted through the hole, the temperature characteristic of the material is tested according to temperature.
摘要翻译：公开了用于对材料的温度特性进行实验的装置和方法。该装置包括用于保持温度均匀的小体积恒温器和用于根据测量碎片的温度变化来测量长度变化的干涉仪。恒温器的内部温度均匀地保持在恒温器周围的材料。当相变改变时，材料长时间保持一致。在恒温器的前表面形成一个孔，以允许光束被透射，从而测量恒温器内的测量碎片的长度变化。通过在通过孔传输光束时以非接触方式测量长度变化，材料的温度特性根据温度进行测试。

5. 发明申请

WO2015140638A1 GLYCOSYLATED VEGF DECOY RECEPTOR FUSION PROTEIN 审中-公开
公开(公告)号：WO2015140638A1
公开(公告)日：2015-09-24
申请号：PCT/IB2015/000674
申请日：2015-03-17
申请人： KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KAIST) , SEOUL NATIONAL UNIVERSITY
发明人： KIM, Ho Min , LEE, Jung-Eun , KIM, Chan , HONG, Hye, Kyoung , WOO, Se, Joon , KOH, Gou, Young , LEE, Gyun, Min
IPC分类号： C12N15/12 , C12N15/63 , C07K14/475 , C07K14/71 , A61K38/17 , A61K38/18 , A61P27/02
CPC分类号： C12N9/12 , A61K33/24 , A61K38/00 , A61K38/45 , A61K39/395 , A61K48/00 , A61K2039/505 , C07K14/71 , C07K16/00 , C07K2319/30 , C07K2319/32 , C07K2319/70 , C07K2319/91 , C12Y207/10001
摘要： The present application describes an isolated nucleic acid molecule encoding a polypeptide capable of synchronously binding VEGF polypeptide and placenta growth factor (PIGF) polypeptide comprising a nucleotide sequence encoding a VEGFR1 component.
摘要翻译：本申请描述了编码能够同时结合VEGF多肽和胎盘生长因子（PIGF）多肽的分离的核酸分子，其包含编码VEGFR1组分的核苷酸序列。

6. 发明申请

WO2014190148A1 NI/CGO AND NI-RU/CGO BASED PRE-REFORMING CATALYSTS FORMULATION FOR METHANE RICH GAS PRODUCTION FROM DIESEL PROCESSING FOR FUEL CELL APPLICATIONS 审中-公开
标题翻译：用于燃料电池应用的柴油加工生产甲烷气体的NI / CGO和NI-RU / CGO的预改性催化剂
公开(公告)号：WO2014190148A1
公开(公告)日：2014-11-27
申请号：PCT/US2014/039132
申请日：2014-05-22
申请人： SAUDI ARABIAN OIL COMPANY , ARAMCO SERVICES COMPANY , KAIST (KOREA ADVANCED INSTITUTE OF SCIENCE & TECH)
发明人： KATIKANENI, Sai, P. , BAE, Joongmyeon , LEE, Shangho
IPC分类号： B01J35/02 , B01J37/18 , B01J38/06 , B01J38/10 , B01J23/755 , B01J23/83 , B01J23/89 , H01M4/00
CPC分类号： C07C4/06 , B01J23/755 , B01J23/76 , B01J23/83 , B01J23/892 , B01J23/894 , B01J35/026 , B01J37/031 , B01J37/18 , B01J38/06 , B01J38/10 , B01J2523/00 , C01B3/40 , C01B2203/0233 , C01B2203/066 , C01B2203/1041 , C01B2203/1058 , C01B2203/1064 , C01B2203/1235 , C01B2203/1247 , C10L3/06 , H01M8/0618 , H01M2008/1293 , Y02E60/525 , Y02P20/52 , Y02P20/584 , Y02P70/56 , B01J2523/3712 , B01J2523/375 , B01J2523/847
摘要： In one aspect, the invention provides a catalyst for converting diesel type liquid hydrocarbons to methane rich gas. The catalyst includes a nickel component, a cerium oxide component, and gadolinium oxide component. The catalysts provide high conversion, selectivity, and stability compare to the state of the art commercial catalysts. The catalyst compositions can improve the overall fuel cell efficiency for both mobile and stationary fuel cell applications.
摘要翻译：一方面，本发明提供了一种用于将柴油型液体烃转化为富甲烷气体的催化剂。催化剂包括镍组分，氧化铈组分和氧化钆组分。与现有技术的商业催化剂相比，催化剂提供高转化率，选择性和稳定性。催化剂组合物可以提高移动和固定燃料电池应用的总体燃料电池效率。

7. 发明申请

WO2014024049A3 METHOD FOR FORMING ENDOTHELIAL CELLS 审中-公开
公开(公告)号：WO2014024049A3
公开(公告)日：2014-02-13
申请号：PCT/IB2013/002502
申请日：2013-08-07
申请人： KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KAIST) , KOH, Gou, Young
发明人： KOH, Gou, Young , JOO, Hyung, Joon , CHOI, Dong, Kyu , PARK, Jin-Sung , CHO, Sung, Woo
IPC分类号： C12N5/071 , C12N15/11 , A61K35/12
摘要： The present application discloses a method of promoting differentiation and expansion of endothelial cells (EC) and cardiomyocytes from a pluripotent cell, which includes contacting the pluripotent cell with a Rho-associated protein kinase (ROCK) suppressor.

8. 发明申请

WO2018080575A1 SYSTEM AND METHOD FOR CORRECTING COLOR OF DIGITAL IMAGE BASED ON THE HUMAN SCLERA AND PUPIL 审中-公开
标题翻译：基于人类SCLERA和瞳孔校正数字图像颜色的系统和方法
公开(公告)号：WO2018080575A1
公开(公告)日：2018-05-03
申请号：PCT/US2017/016384
申请日：2017-02-03
申请人： ELC MANAGEMENT LLC , KAIST UNIVERSITY
发明人： SUK, Hyeon-Jeong , CHOI, Kyungah , CHOI, Hayan , KIM, Songyup
IPC分类号： G06T5/00 , G06T7/11 , G06T7/33 , G06T7/90 , G06K9/00
摘要： The color correction method in accordance with an embodiment of the present invention can comprise the steps of: acquiring an image from a captured image; detecting the face and eyes from the captured image; separating the sclera and pupil of the detected eye(s); correcting the image by comparing the areas of the sclera and pupil extracted by separating the sclera and pupil with the reference values stored in a database; and extracting the skin color of the face from the corrected image.
摘要翻译：根据本发明实施例的色彩校正方法可以包括以下步骤：从捕获的图像获取图像; 从拍摄的图像中检测脸部和眼睛; 分离检测到的眼睛的巩膜和瞳孔; 通过将通过将巩膜和瞳孔分离而提取的巩膜和瞳孔的面积与存储在数据库中的参考值进行比较来校正图像; 并从修正后的图像中提取脸部的肤色。

9. 发明申请

WO2009022839A2 NOVEL METHOD FOR PREPARING PREGABALIN 审中-公开
标题翻译：制备PREGABALIN的新方法
公开(公告)号：WO2009022839A2
公开(公告)日：2009-02-19
申请号：PCT/KR2008/004672
申请日：2008-08-11
申请人： KAIST , LEE, Hee-Seung , LEE, Joohee , OK, Taedong
发明人： LEE, Hee-Seung , LEE, Joohee , OK, Taedong
IPC分类号： C07C227/12
CPC分类号： C07C229/08
摘要： The present invention relates to a method for preparing pregabalin{ (S) -3- (aminomethyl) -5-methylhexanoic acid}, which is useful for the prevention and treatment of seizure disorders, pains, and psychiatric disorders. According to the present invention, pregabalin can be prepared in a high enantiomeric excess of 99% or more, without an additional step of separating or purifying its enantiomer.
摘要翻译：本发明涉及制备普瑞巴林{（S）-3-（氨基甲基）-5-甲基己酸}的方法，其用于预防和治疗癫痫症，疼痛和精神障碍。根据本发明，普瑞巴林可以以99％或更高的高对映体过量制备，而无需另外的分离或纯化其对映体的步骤。

10. 发明申请

WO2006005981A3 SHARED HIGH-INTENSITY BROADBAND LIGHT SOURCE FOR WAVELENGTH-DIVISION MULTIPLE ACCESS PASSIVE OPTICAL NETWORK 审中-公开
公开(公告)号：WO2006005981A3
公开(公告)日：2006-01-19
申请号：PCT/IB2004/002187
申请日：2004-06-01
申请人： NOVERA OPTICS KOREA CO. LTD , INSTITUTE OF INFORMATION TECHNOLOGY ASSESMENT , KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KAIST) , LEE, Chang, Hee , OH, Tae, Won , KIM, Bong, Soo
发明人： LEE, Chang, Hee , OH, Tae, Won , KIM, Bong, Soo
IPC分类号： H04J14/02
摘要： An optical power distributor is coupled to a high-intensity broadband light source to distribute in a shared manner an output of the high-intensity broadband light source to a plurality of optical line terminals. A depolarizer is also described having an input coupled to an output of a polarized broadband light source. A first integrated module has optical transmitters and an optical wavelength router for a first band. A second integrated module has optical receivers and an optical wavelength router for a second band.

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