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    • 2. 发明申请
    • FLUIDIZED BED SYSTEMS AND METHODS INCLUDING SECONDARY GAS FLOW
    • 流化床系统和包括二次气流的方法
    • WO2008061015A3
    • 2008-07-24
    • PCT/US2007084284
    • 2007-11-09
    • NEW JERSEY TECH INSTEVONIK DEGUSSA GMBHPFEFFER ROBERTQUEVEDO JOSE AJUERGEN FLESCH
    • PFEFFER ROBERTQUEVEDO JOSE AJUERGEN FLESCH
    • B01J8/18B01F13/02B01J8/24B01J8/32
    • B01J8/32B01F3/18B01F13/02B01F13/0272B01J8/1818B01J8/1872B82Y15/00B82Y30/00
    • Methods and systems for enhancing fluidization of nanoparticle and/or nanoagglomerates and for mixing nanoparticle/nanoagglomerate systems at the nanoscale are provided. A fluidization chamber is provided with a fluidizing medium (e.g., a fluidizing gas) directed in a first fluidizing direction, e.g., upward into and through a bed containing a volume of nanoparticles and/or nanopowders. A second source of air/gas flow is provided with respect to the fluidization chamber, the secondary air/gas flow generally being oppositely (or substantially oppositely) directed relative to the fluidizing medium. Turbulence created by the secondary gas flow, e.g., a jet from a micro-jet nozzle, is advantageously effective to aerate the agglomerates and the shear generated by the jet is advantageously effective to break apart nanoagglomerates and/or reduce the tendency for nanoagglomerates to form or reform. A downwardly directed source of secondary gas flow located near the main gas distributor leads to full fluidization of the entire amount of powder in the column. In addition, the oppositely directed fluid flow facilitates powder circulation within the fluidization chamber, thereby enhancing fluidization and mixing/blending results.
    • 提供了用于增强纳米粒子和/或纳米团聚体的流化和用于以纳米级混合纳米粒子/纳米团聚体系统的方法和系统。 流化室设置有沿第一流化方向(例如向上进入并穿过含有一定体积的纳米颗粒和/或纳米粉末的床)的流化介质(例如流化气体)。 相对于流化室提供第二空气/气流来源,第二空气/气流通常相对于流化介质相反(或基本相反)。 由二次气流产生的湍流,例如来自微喷嘴的射流有利地有效地使附聚物充气,并且由射流产生的剪切有利地有效地分解纳米团聚体和/或减小纳米团聚体形成的倾向 或改革。 位于主气体分配器附近的向下定向的二次气流来源导致塔中全部粉末的充分流化。 另外,相反方向的流体流动促进了流化室内的粉末循环,从而增强了流化和混合/混合结果。
    • 5. 发明申请
    • ORDERED PARTICLE STRUCTURES AND METHODS OF MAKING SAME
    • 订购颗粒结构及其制备方法
    • WO2005103137A3
    • 2009-04-02
    • PCT/US2004036386
    • 2004-11-02
    • NEW JERSEY TECH INST
    • GOGOS COSTASYOUNG MING-WANDAVE RAJESHPFEFFER ROBERTDAVIDSON THEODORETODD DAVIDQIAN BAINIANYANG JUN
    • C06B25/34C08J3/12C08K7/00C08L1/28C08L3/02C10L5/00
    • C08J3/12C08J2303/02C08L1/284C08L3/02C08L2666/26
    • Techniques and methods of formation of ordered mixtures of particles by "clustering". Clustering comprises local "structuring" consisting of a large "host" and smaller "guest" particles by various techniques. Small amounts of polymer are coated onto solid particles by various means. In one embodiment, an ordered mixture is created wherein the material that is of lesser quantity is of small particle size (the "B" particles) and the "A" particles are of larger size, The "B" particles are then coated onto a single A particle. By creating this ordered structure, each composite particle has the proper or stoichiometric amount of all ingredients. This dry composite material produced is appropriately used in various applications such as pharmaceutical formulations in the form of tablets, capsules, oral suspensions, inhalant, parental formulations and the like; energetics manufacture such as but not limited to explosives, propellants and pyrotechnics; agricultural products including but not limited to fertilizers, herbicides and pesticides; nutritional supplements and the like.
    • 通过“聚类”形成有序粒子混合物的技术和方法。 聚类包括通过各种技术由大型“主机”和较小的“客体”粒子组成的本地“结构化”。 少量聚合物通过各种方式涂覆在固体颗粒上。 在一个实施方案中,产生有序混合物,其中少量的材料具有较小的粒度(“B”颗粒)和“A”)颗粒的尺寸较大。然后将“B”颗粒涂覆到 单A颗粒。 通过创建这种有序结构,每个复合颗粒具有适当或化学计量的所有成分。 生产的这种干燥复合材料适用于各种应用,例如片剂,胶囊,口服悬浮液,吸入剂,亲本制剂等形式的药物制剂; 能源制造,例如但不限于爆炸物,推进剂和烟火; 农产品包括但不限于化肥,除草剂和农药; 营养补品等。
    • 6. 发明申请
    • SYSTEM AND METHOD FOR NANOPARTICLE AND NANOGGLOMERATE FLUIDIZATION
    • 用于纳米颗粒和纳米粒子流化的系统和方法
    • WO2005022667A3
    • 2006-03-30
    • PCT/US2004025514
    • 2004-07-28
    • NEW JERSEY TECH INST
    • PFEFFER ROBERTNAM CAROLINE HDAVE RAJESH NLIU GUANGLIANGQUEVEDO JOSE AYU QUNZHU CHAO
    • B01F11/02B01F13/02B01F13/08B01J8/24B01J8/40B01J8/42B01J19/10H01M20060101B02C19/06
    • B01F13/0809B01F11/0266B01F13/0255B01J8/1872B01J8/40B01J8/42B01J19/10B01J2208/00681B82Y15/00
    • With the coupling of an external field and aeration (or a flow of another gas), nanoparticles can be smoothly and vigorously fluidized. Multiple external fields and/or pre­treatment may be employed with the fluidizing gas: sieving, magnetic assistance, vibration, acoustic/sound or rotational/centrifugal forces. Any of these forces, either alone or in combination, when coupled with a fluidizing medium, provide excellent means for achieving homogenous nanofluidization. The additional force(s) help to break channels as well as provide enough energy to disrupt the strong interparticle forces, thereby establishing an advantageous agglomerate size distribution. Enhanced fluidization is reflected by at least one of the following performance-related attributes: reduced levels of bubbles within the fluidized system, reduced gas bypass relative to the fluidized bed, smooth fluidization behavior, reduced elutriation, a high level of bed expansion, reduced gas velocity levels to achieve desired fluidization performance, and/or enhanced control of agglomerate size/distribution. The fluidized nanoparticles may be coated, surface-treated and/or surface­modified in the fluidized state. In addition, the fluidized nanoparticles may participate in a reaction, either as a reactant or a catalyst, while in the fluidized state.
    • 通过外场和通气(或另一种气体的流动)的耦合,纳米颗粒可以顺利且剧烈流化。 多种外部场和/或预处理可以与流化气体一起使用:筛分,磁辅助,振动,声/声或旋转/离心力。 当与流化介质结合时,单独或组合的这些力中的任何一个提供了实现均匀纳米流化的极好手段。 额外的力有助于破坏通道,并提供足够的能量来破坏强大的颗粒间力,从而建立有利的聚集体尺寸分布。 增强的流化反应由以下性能相关属性中的至少一个反映:流化系统内的气泡水平降低,相对于流化床的气体旁路减少,流化性能平稳,淘汰率降低,床膨胀高度降低 速度水平以实现期望的流化性能,和/或增强聚集体尺寸/分布的控制。 流化的纳米颗粒可以在流化状态下被涂覆,表面处理和/或表面改性。 此外,流化的纳米颗粒可以在流化状态下作为反应物或催化剂参与反应。