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1. 发明申请

WO2009023061A2 DIELECTRICS USING SUBSTANTIALLY LONGITUDINALLY ORIENTED INSULATED CONDUCTIVE WIRES 审中-公开
标题翻译：介质使用大体垂直绝缘导电线
公开(公告)号：WO2009023061A2
公开(公告)日：2009-02-19
申请号：PCT/US2008007211
申请日：2008-06-10
申请人： NANOSYS INC , DUBROW ROBERT S , MILLER JEFFREY , STUMBO DAVID P
发明人： DUBROW ROBERT S , MILLER JEFFREY , STUMBO DAVID P
IPC分类号： H01G4/10
CPC分类号： H01B7/0009 , B82Y99/00 , H01B3/004 , H01G4/018 , H01G4/20 , Y10T428/249924
摘要： A dielectric material is disclosed comprising a plurality of substantially longitudinally oriented wires which are coupled together, wherein each of the wires includes a conductive core comprising a first material and one or more insulating shell layers comprising a compositionally different second material disposed about the core. In one embodiment, a dielectric layer is disclosed comprising a substrate comprising an insulating material having a plurality of nanoscale pores defined therein having a pore diameter less than about 100 nm, and a conductive material disposed within the nanoscale pores. Methods are also disclosed to create a dielectric material layer comprising, for example, providing a plurality of wires, wherein each of the wires includes a core comprising a first material and one or more insulating layers comprising a compositionally different second material disposed about the core; substantially longitudinally orienting said plurality of wires along their long axes; coupling the wires together; and depositing an insulating coating on at least one of a top and/or a bottom end of the wires.
摘要翻译：公开了一种介电材料，其包括多个基本上纵向定向的导线，所述导线耦合在一起，其中每个导线包括包含第一材料的导电芯和包含围绕芯设置的组成不同的第二材料的一个或多个绝缘壳层。在一个实施例中，公开了一种介电层，该介电层包括含有绝缘材料的衬底和设置在纳米级孔内的导电材料，绝缘材料具有限定在其中的多个纳米级孔隙，孔隙直径小于约100nm。还公开了制造电介质材料层的方法，该电介质材料层例如包括提供多个导线，其中每个导线包括包含第一材料的芯和包含围绕芯布置的组成不同的第二材料的一个或多个绝缘层; 使所述多根丝线沿其长轴基本纵向定向; 将导线连接在一起; 以及在导线的顶端和/或底端中的至少一个上沉积绝缘涂层。

2. 发明申请

WO2008060455A3 METHODS FOR NANOWIRE ALIGNMENT AND DEPOSITION 审中-公开
标题翻译：纳米线对准和沉积方法
公开(公告)号：WO2008060455A3
公开(公告)日：2008-11-20
申请号：PCT/US2007023625
申请日：2007-11-09
申请人： NANOSYS INC , SHARP KK , MARTIN SAMUEL , DUAN XIANGFENG , FUJII KATSUMASA , HAMILTON JAMES M , IWATA HIROSHI , LEON FRANCISCO , MILLER JEFFREY , NEGISHI TETSU , OHKI HIROSHI , PARCE J WALLACE , PEREIRA CHERI X Y , SCHUELE PAUL JOHN , SHIBATA AKIHIDE , STUMBO DAVID P , OKADA YASUNOBU
发明人： MARTIN SAMUEL , DUAN XIANGFENG , FUJII KATSUMASA , HAMILTON JAMES M , IWATA HIROSHI , LEON FRANCISCO , MILLER JEFFREY , NEGISHI TETSU , OHKI HIROSHI , PARCE J WALLACE , PEREIRA CHERI X Y , SCHUELE PAUL JOHN , SHIBATA AKIHIDE , STUMBO DAVID P , OKADA YASUNOBU
IPC分类号： H01L21/00 , B82B3/00
CPC分类号： H01L29/0665 , B82B3/00 , B82Y10/00 , B82Y30/00 , B82Y40/00 , H01L29/0673 , Y10S977/883
摘要： The present invention provides methods and systems for nanowire alignment and deposition. Energizing (e.g., an alternating current electric field) is used to align and associate nanowires with electrodes. By modulating the energizing, the nanowires are coupled to the electrodes such that they remain in place during subsequent wash and drying steps. The invention also provides methods for transferring nanowires from one substrate to another in order to prepare various device substrates. The present invention also provides methods for monitoring and controlling the number of nanowires deposited at a particular electrode pair, as well as methods for manipulating nanowires in solution.
摘要翻译：本发明提供用于纳米线对准和沉积的方法和系统。通电（例如，交流电场）用于将纳米线与电极对齐和关联。通过调节激励，纳米线连接到电极，使得它们在随后的洗涤和干燥步骤中保持在原位。本发明还提供了用于将纳米线从一个衬底转移到另一衬底以制备各种器件衬底的方法。本发明还提供了用于监测和控制沉积在特定电极对处的纳米线数量的方法，以及用于在溶液中操纵纳米线的方法。

3. 发明申请

WO2009108173A3 METHODS FOR FORMATION OF SUBSTRATE ELEMENTS 审中-公开
标题翻译：形成基底元素的方法
公开(公告)号：WO2009108173A3
公开(公告)日：2009-12-30
申请号：PCT/US2008013499
申请日：2008-12-09
申请人： NANOSYS INC , LEON FRANCISCO , LEMMI FRANCESCO , MILLER JEFFREY , DUTTON DAVID , STUMBO DAVID P
发明人： LEON FRANCISCO , LEMMI FRANCESCO , MILLER JEFFREY , DUTTON DAVID , STUMBO DAVID P
IPC分类号： H01L21/00
CPC分类号： H01L29/0665 , B81C1/00142 , B82Y10/00 , B82Y40/00 , H01L29/0673 , H01L29/42392 , H01L29/66439 , H01L29/66772 , H01L29/775 , H01L29/78603 , H01L29/78696
摘要： The present invention relates to methods of forming substrate elements, including semiconductor elements such as nanowires, transistors and other structures, as well as the elements formed by such methods.
摘要翻译：本发明涉及形成衬底元件的方法，包括诸如纳米线，晶体管和其它结构的半导体元件，以及由这些方法形成的元件。

4. 发明申请

WO2009152215A3 QUILTED IMPLANTABLE GRAFT 审中-公开
标题翻译：带有可植入的花纹
公开(公告)号：WO2009152215A3
公开(公告)日：2010-09-02
申请号：PCT/US2009046857
申请日：2009-06-10
申请人： COOK BIOTECH INC , MILLER JEFFREY , PATEL UMESH H
发明人： MILLER JEFFREY , PATEL UMESH H
IPC分类号： A61L27/24 , A61L27/36 , A61L27/58 , B32B5/26
CPC分类号： A61L27/3633 , A61L27/14 , A61L27/38 , A61L27/50 , A61L27/56 , B32B5/06 , B32B5/26 , B32B7/08 , B32B2262/08 , B32B2307/7163 , B32B2535/00
摘要： Described are embodiments of a multilaminate or multiple layer implantable surgical graft comprising remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.
摘要翻译：描述了包括可重塑的胶原片材料的多层或多层可植入手术移植物的实施方案，所述移植物包括一个或多个交织构件，以将移植物缝合在一起，以帮助防止层在处理过程中的分层或分离以及重塑的初始阶段。交织构件可以包括以期望的图案编织穿过生物材料层的缝合线，线，单个线迹，材料条等。在一个实施方案中，交织构件包含药理学活性物质，例如药物，生长因子等，以在宿主组织中引发所需的生物反应。在另一个实施方案中，移植物还包括在可重塑生物材料层内的增强材料，例如合成网，并由一个或多个交织构件缝合在一起。

5. 发明申请

WO2017048809A8 NK CELLS EXHIBITING AN ADAPTIVE PHENOTYPE AND METHODS FOR PREPARING AND FOR USING 审中-公开
标题翻译：展示自适应表型的NK细胞及其制备和使用方法
公开(公告)号：WO2017048809A8
公开(公告)日：2017-06-29
申请号：PCT/US2016051685
申请日：2016-09-14
申请人： UNIV MINNESOTA , MILLER JEFFREY , CICHOCKI FRANK , BRYCESON YENAN , SCHLUMS HEINRICH
发明人： MILLER JEFFREY , CICHOCKI FRANK , BRYCESON YENAN , SCHLUMS HEINRICH
IPC分类号： A61K35/17 , C12N5/0783
CPC分类号： C12N5/0646 , A61K35/17 , C12N2501/2315 , C12N2501/2321 , C12N2501/42 , C12N2502/1352
摘要： This disclosure describes an adaptive NK cell, an isolated population of adaptive Natural Killer (NK) cells, a composition including an adaptive NK cell, and methods for producing, preparing, and using an adaptive NK cell or an isolated population or composition including an adaptive NK cell. The adaptive NK cells may be used to treat a viral infection or a tumor.
摘要翻译：本公开描述了适应性NK细胞，适应性自然杀伤（NK）细胞的分离群体，包含适应性NK细胞的组合物，以及用于产生，制备和使用适应性NK细胞或分离的群体或组合物的方法， NK细胞。适应性NK细胞可用于治疗病毒感染或肿瘤。

6. 发明申请

WO2008009664A2 TREATMENT OF PAIN 审中-公开
标题翻译：治疗疼痛
公开(公告)号：WO2008009664A2
公开(公告)日：2008-01-24
申请号：PCT/EP2007057344
申请日：2007-07-17
申请人： BOEHRINGER INGELHEIM INT , BOEHRINGER INGELHEIM PHARMA , ROSENBURG RONALD , MILLER JEFFREY
发明人： ROSENBURG RONALD , MILLER JEFFREY
IPC分类号： A61K31/426 , A61K9/20 , A61K31/5415 , A61P29/00
CPC分类号： A61K45/06 , A61K9/0019 , A61K9/0031 , A61K9/02 , A61K9/08 , A61K9/1617 , A61K9/1635 , A61K9/1641 , A61K9/1652 , A61K9/2018 , A61K9/2027 , A61K9/2054 , A61K9/2059 , A61K9/5026 , A61K9/5047 , A61K31/426 , A61K31/5415 , A61K47/34 , A61K2300/00
摘要： The invention relates to a new medicamentation for the treatment of pain, in particular fibromyalgia. The medicamentation comprises the administration of pramipexole and meloxicam. The medicamentation is a combination of pramipexole an meloxicam which may be used in a fixed dose combination as well as in a free dose combination. The invention further is related to the manufacture of a medicament for the treatment of pain, in particular fibromyalgia comprising said medicamentation and a method of treatment of pain, in particular fibromyalgia comprising said medicamentation.
摘要翻译：本发明涉及用于治疗疼痛，特别是纤维肌痛的新药物。药物包括给予普拉克索和美洛昔康。药物是普拉克索美洛昔康的组合，其可以以固定剂量组合以及游离剂量组合使用。本发明还涉及用于治疗疼痛的药物的制备，特别是包括所述药物的纤维肌痛和治疗疼痛的方法，特别是包含所述药物化学的纤维肌痛。

7. 发明申请

WO2007011552A3 ORAL COOMPOSITIONS HAVING CATIONIC ACTIVE INGREDIENTS 审中-公开
标题翻译：具有阳离子活性成分的口服组合物
公开(公告)号：WO2007011552A3
公开(公告)日：2007-04-05
申请号：PCT/US2006026512
申请日：2006-07-10
申请人： COLGATE PALMOLIVE CO , MILLER JEFFREY , BOYD THOMAS J , ARVANITIDOU EVANGELIA S , PRENCIPE MICHAEL , MORGAN ANDRE
发明人： MILLER JEFFREY , BOYD THOMAS J , ARVANITIDOU EVANGELIA S , PRENCIPE MICHAEL , MORGAN ANDRE
IPC分类号： A61Q11/00 , A61K8/24 , A61K8/41 , A61K8/43
CPC分类号： A61K8/41 , A61K8/24 , A61K8/43 , A61Q11/00
摘要： An oral composition is provided covering one or more cationic active ingredients and a cationic-compatible inorganic particulate having a porous surface that is substantially inert to the cationic active ingredient. The oral composition also has a cationic-compatible surfactant system and a carrier that is stable in the presence of the cationic active ingredient. The oral composition can be provided in a dual tube or single tube form, if desired.
摘要翻译：提供覆盖一种或多种阳离子活性成分和具有对阳离子活性成分基本惰性的多孔表面的阳离子相容性无机颗粒的口腔组合物。口服组合物还具有阳离子相容的表面活性剂体系和在阳离子活性成分存在下稳定的载体。如果需要，口腔组合物可以以双管或单管形式提供。

8. 发明申请

WO2009134949A8 SELF DEPLOYING SIS IN NEEDLE 审中-公开
标题翻译：自己在针脚上部署SIS
公开(公告)号：WO2009134949A8
公开(公告)日：2010-01-21
申请号：PCT/US2009042200
申请日：2009-04-30
申请人： COOK BIOTECH INC , CHEN STEVE , DEMPSEY RYAN , MILLER JEFFREY , OVERBY AMY
发明人： CHEN STEVE , DEMPSEY RYAN , MILLER JEFFREY , OVERBY AMY
IPC分类号： A61B17/34 , A61B17/00 , A61B17/06 , A61F2/00
CPC分类号： A61F2/0059 , A61B17/3468 , A61B2017/00792 , A61B2017/00862 , A61B2017/00969 , A61B2017/061 , A61F2/0077
摘要： Described, in certain inventive embodiments, are unique devices and methods for introducing implants into soft tissue of a patient. One of these devices includes a tissue-penetrating member (21) that is configured to pass in its entirety through a volume of patient tissue. The tissue-penetrating member has a leading end (23) and a trailing end (24), and provides a receiving space for receipt of an implant body portion (28) for carrying the implant body portion into the volume of patient tissue. The device also includes an implant (22) that has an implant body portion removably received in the receiving space of the tissue-penetrating member. The implant body portion is configured for deployment from the receiving space in the volume of patient tissue so as to remain deployed there along a passageway traversed by the tissue-penetrating member.
摘要翻译：在某些发明实施例中描述了用于将植入物引入患者的软组织中的独特装置和方法。这些装置中的一个包括组织穿透构件（21），其构造成使其整体通过一定体积的患者组织。组织穿透构件具有前端（23）和后端（24），并且提供用于接收植入物主体部分（28）的接收空间，用于将植入物主体部分运送到患者组织的体积中。该装置还包括植入物（22），其具有可移除地容纳在组织穿透构件的容纳空间中的植入物主体部分。植入物主体部分构造成从患者组织体积中的接收空间展开，以便沿着由组织穿透构件穿过的通道保持展开。

9. 发明申请

WO2008086275A2 PAIRING A MEDIA SERVER AND A MEDIA CLIENT 审中-公开
标题翻译：配对媒体服务器和媒体客户端
公开(公告)号：WO2008086275A2
公开(公告)日：2008-07-17
申请号：PCT/US2008050385
申请日：2008-01-07
申请人： APPLE INC , ROBBIN JEFFREY , WYSOCKI CHRISTOPHER , JAWA AMANDEEP , MILLER JEFFREY , HELLER DAVID , HENZIE JUSTIN , BRODERSEN RAINER , PACURARIU MIHNEA CALIN
发明人： ROBBIN JEFFREY , WYSOCKI CHRISTOPHER , JAWA AMANDEEP , MILLER JEFFREY , HELLER DAVID , HENZIE JUSTIN , BRODERSEN RAINER , PACURARIU MIHNEA CALIN
IPC分类号： H04L29/06 , G06Q20/00 , H04L29/08
CPC分类号： H04L67/42 , H04L65/1069 , H04L65/4084 , H04L65/60 , H04L67/322
摘要： A system for use in presenting media content includes a media server configured to provide media content and a media client configured to obtain the media content from the media server and to present the media content on a device. The media client is configured to generate a first code and to transmit information to the media server. The information identifies the media client and the information indicates that the media client is available for pairing. The media server is configured to reply to the information with a second code that corresponds to the first code in order to enable pairing between the media server and the media client.
摘要翻译：用于呈现媒体内容的系统包括被配置为提供媒体内容的媒体服务器和被配置为从媒体服务器获取媒体内容并且将媒体内容呈现在设备上的媒体客户端。媒体客户端被配置为生成第一代码并将信息传送到媒体服务器。信息标识媒体客户端，信息表示媒体客户端可用于配对。媒体服务器被配置为使用与第一代码相对应的第二代码来回复信息，以便启用媒体服务器和媒体客户端之间的配对。

10. 发明申请

WO2008076290A2 OPTIMIZED NON-CANONICAL ZINC FINGER PROTEINS 审中-公开
标题翻译：优化的非正则锌指蛋白
公开(公告)号：WO2008076290A2
公开(公告)日：2008-06-26
申请号：PCT/US2007025455
申请日：2007-12-13
申请人： DOW AGROSCIENCES LLC , SANGAMO BIOSCIENCES INC , CAI QIHUA C , MILLER JEFFREY , URNOV FYODOR , SHUKLA VIPULA K , PETOLINO JOSEPH F , BAKER LISA W , GARRISON ROBBI J , BLUE RYAN C , MITCHELL JON C , ARNOLD NICOLE L , WORDEN SARAH E
发明人： CAI QIHUA C , MILLER JEFFREY , URNOV FYODOR , SHUKLA VIPULA K , PETOLINO JOSEPH F , BAKER LISA W , GARRISON ROBBI J , BLUE RYAN C , MITCHELL JON C , ARNOLD NICOLE L , WORDEN SARAH E
CPC分类号： C07K14/4702 , C07K2319/81 , C12N15/8213 , C12N15/8243
摘要： Disclosed herein are zinc fingers comprising CCHC zinc coordinating residues. Also described are zinc finger proteins and fusion proteins comprising these CCHC zinc fingers as well as polynucleotides encoding these proteins. Methods of using these proteins for gene editing and gene regulation are also described
摘要翻译：本文公开了包含CCHC锌配位残基的锌指。还描述了锌指蛋白和包含这些CCHC锌指的融合蛋白以及编码这些蛋白的多核苷酸。还描述了使用这些蛋白质进行基因编辑和基因调节的方法

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