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1. 发明申请

WO2005091953A3 MORINDA CITRIFOLIA LEAF EXTRACT COMPOSITIONS AND METHODS OF OBTAINING THE SAME 审中-公开
标题翻译：茉莉花叶提取物组合物及其获得方法
公开(公告)号：WO2005091953A3
公开(公告)日：2007-04-12
申请号：PCT/US2005006923
申请日：2005-03-04
申请人： MORINDA INC , ZHOU BING-NAN , PALU AFA KEHAATI , SU CHEN , JENSEN CLAUDE JARAKAE , STORY STEPHEN
发明人： ZHOU BING-NAN , PALU AFA KEHAATI , SU CHEN , JENSEN CLAUDE JARAKAE , STORY STEPHEN
IPC分类号： A61K36/746 , A61K36/00
CPC分类号： A61K36/746
摘要： Methods and compositions relating to leaf extracts obtained from removing liquids from relatively dry Morinda citrifolia leaves. Methods and compositions relating to a leaf serum created from combining leaf extract and fruit juice from the Morinda citrifolia L. plant. Methods and compositions relating to leaf extract compositions comprising one or more of the leaf extracts and leaf serums.
摘要翻译：与从相对干燥的香茅草叶中除去液体获得的叶提取物相关的方法和组合物。与从叶片提取物和来自海巴戟天植物的果汁组合产生的叶片血清的方法和组合物。涉及包含一种或多种叶提取物和叶血清的叶提取物组合物的方法和组合物。

2. 发明申请

WO2006104892A2 MORINDA CITRIFOLIA BASED ANTIFUNGAL FORMULATIONS AND METHODS 审中-公开
标题翻译：基于MORINDA CITRIFOLIA的反义制剂和方法
公开(公告)号：WO2006104892A2
公开(公告)日：2006-10-05
申请号：PCT/US2006010798
申请日：2006-03-24
申请人： MORINDA INC , ISAMI FUMIYUKI , WADSWORTH JOHN W , GERSON SCOTT , PALU AFA KEHAATI , ZHOU BING-NAN , JENSEN CLAUDE JARAKAE , STORY STEPHEN P
发明人： ISAMI FUMIYUKI , WADSWORTH JOHN W , GERSON SCOTT , PALU AFA KEHAATI , ZHOU BING-NAN , JENSEN CLAUDE JARAKAE , STORY STEPHEN P
IPC分类号： A61K31/7048 , A01N65/00 , A61K31/353
CPC分类号： C05G3/02 , A01N65/08 , A23B7/154 , A23L3/3472 , A23L3/3481 , A23V2002/00 , A61K36/746 , A23V2200/10 , A23V2250/21168 , A23V2250/2117 , A01N43/16
摘要： The present invention provides a formulation which may be utilized in agricultural practice that is eco-friendly and effective as plant growth promotion agent, soil improvement agent, bactericide and insecticide agent, disease and harmful insect prevention agent, and is suitable for organic farming. The formulation of the present invention is comprised of a Morinda citrifolia product or extract. The formulation of the present invention may be applied to fruit vegetables, leafy vegetables, root vegetables, grains as well as flowers and shrubs, increasing the amount of yield and extending freshness period after harvest. Further, the present invention relates to antifungal and antibacterial activity of processed Morinda citrifolia products, as well as from various fractions of extracts from these processed products and the Morinda citrifolia L plant, and related methods to determine mean inhibitory concentrations. In particular, the present invention relates to ethanol, methanol and ethyl acetate extracts from Morinda citrifolia L. and their inhibitory activities on common fungi and bacteria and the identification of mean inhibitory concentrations.
摘要翻译：本发明提供一种可用于农业实践中的作为植物生长促进剂，土壤改良剂，杀菌剂和杀虫剂，疾病和害虫防治剂的生态友好和有效的制剂，并且适用于有机农业。本发明的制剂由海巴戟天产品或提取物组成。本发明的制剂可应用于水果蔬菜，叶菜类，根类蔬菜，谷物以及花和灌木，收获后增加产量和延长新鲜期。此外，本发明涉及加工的海巴戟天产品的抗真菌和抗菌活性，以及来自这些加工产品的提取物和Morinda citrifolia L植物的各种馏分以及确定平均抑制浓度的相关方法。特别地，本发明涉及来自海巴戟天的乙醇，甲醇和乙酸乙酯提取物及其对常见真菌和细菌的抑制活性以及平均抑制浓度的鉴定。

3. 发明申请

WO2005086834A2 METHODS AND COMPOSITIONS FOR REACTIVATING ACETYLCHOLINESTERASE 审中-公开
标题翻译：反应乙酰胆碱酯酶的方法和组合物
公开(公告)号：WO2005086834A2
公开(公告)日：2005-09-22
申请号：PCT/US2005007662
申请日：2005-03-09
申请人： MORINDA INC , PALU AFA KEHAATI , WEST BRETT , ZHOU BING-NAN , JENSEN JARAKAE , STORY STEPHEN
发明人： PALU AFA KEHAATI , WEST BRETT , ZHOU BING-NAN , JENSEN JARAKAE , STORY STEPHEN
IPC分类号： A61K36/746 , A61K45/06
CPC分类号： A61K36/746 , A61K45/06 , A61K2300/00
摘要： The present invention relates to methods and compositions for reactivating Acetylcholinesterase in living organisms using contents from the Morinda citrifolia L. plant. More particularly, the present invention relates to methods and compositions involving the reactivation of Acetylcholinesterase using fruit juice obtained from the Morinda citrifolia L. plant.
摘要翻译：本发明涉及使用来自Morinda citrifolia L.植物的内含物活化生物体中的乙酰胆碱酯酶的方法和组合物。更具体地说，本发明涉及使用从Morinda citrifolia L.植物获得的果汁重新活化乙酰胆碱酯酶的方法和组合物。

4. 发明申请

WO2004091545A2 SELECTIVELY INHIBITING ESTROGEN PRODUCTION AND PROVIDING ESTROGENIC EFFECTS IN THE HUMAN BODY 审中-公开
标题翻译：选择性抑制雌激素在人体内的生产和提供雌激素作用
公开(公告)号：WO2004091545A2
公开(公告)日：2004-10-28
申请号：PCT/US2004009129
申请日：2004-03-25
申请人： MORINDA INC , PALU AFA KEHAATI
发明人： PALU AFA KEHAATI , WANG MIAN YING , SU CHEN XING , WEST BRETT JUSTIN , WESTENDORF JOHANNES JOSEPH , JENSEN CLAUDE JARAKAE , STORY STEPHEN PAUL
IPC分类号： A61K31/353 , A61K36/00 , A61K36/746 , A61K
CPC分类号： A61K36/746 , A61K31/353
摘要： Implementation is directed to selectively inhibiting estrogen production and providing estrogenic effects in a human body. A dietary supplement includes a processed Morinda citrifolia product that is used to inhibit aromatase or aromatase enzymes that function to convert androgens to estrogens, inhibit receptors from binding with estrogen, and reduce and/or regulate estrogen production, as well as reduce the amount of estrogen produced within the body and regulating such production. The dietary supplement further provides estrogenic effects. The present invention methods and compositions effectively function to treat estrogen-dependent cancers, and particularly inhibit, destroy, and reverse the effects of of estrogendependent cancerous tumors through the introduction into the body (e.g. ingesting) a safe, pre-determined dosage of a naturaceutical composition formulated with or comprising one or more processed Morinda citrifolia products for a safe, predetermined duration.
摘要翻译：实施的目的是选择性地抑制雌激素产生并在人体内提供雌激素作用。膳食补充剂包括加工的Morinda citrifolia产品，其用于抑制将雄激素转化成雌激素，抑制受体与雌激素结合的芳香酶或芳香酶，以及减少和/或调节雌激素的产生以及减少雌激素的量在体内生产并调节这种生产。膳食补充剂进一步提供雌激素作用。本发明的方法和组合物有效地用于治疗雌激素依赖性癌症，特别是抑制，破坏和逆转雌激素依赖性癌性肿瘤的作用通过引入体内（例如摄取）安全的预定剂量的药物配制或包含一种或多种加工的Morinda citrifolia产品的组合物用于安全的，预定的持续时间。

5. 发明申请

WO2007064521A3 MORINDA CITRIFOLIA LEAF JUICE AND LEAF EXTRACT BASED FORMULATIONS 审中-公开
标题翻译： MORINDA CITRIFOLIA LEAF JUICE和LEAF提取物制剂
公开(公告)号：WO2007064521A3
公开(公告)日：2010-02-18
申请号：PCT/US2006044949
申请日：2006-11-21
申请人： TAHITIAN NONI INT INC , PALU AFA KEHAATI , ZHOU BING-NAN , SU CHEN XING , JENSEN CLAUDE JARAKAE , WEST BRETT JUSTIN , STORY STEPHEN P
发明人： PALU AFA KEHAATI , ZHOU BING-NAN , SU CHEN XING , JENSEN CLAUDE JARAKAE , WEST BRETT JUSTIN , STORY STEPHEN P
IPC分类号： A61K36/746 , A61K36/00
CPC分类号： A61K36/746
摘要： A method and composition for inhibiting certain enzymes, where such inhibition results in various health benefits is provided. More particularly, a method and composition using one or more of the following: Noni Leaf Extract; Noni Leaf Juice; and/or Roast Leaf to inhibit the following: HMG-CoA Reductase; Phosphodiesterases (3 and 4) PDE3 and PDE4; 5 -Lipoxygenase (LOX) and 15-LOX; Xanthine Oxidase (XO); Gamma Amino Butyric Acid (GABA) and the growth of the second most common human skin cancer cell line, is provided. Moreover, the foregoing enzymatic inhibitions result in: alleviating pain and inflammation; treating prostate cancers; lowering cholesterol levels; counteracting Diabetes Type II; maintaining the highest possible integrity of cellular interactions in the brain resulting in an undisturbed neural function, (i.e., neuroprotection); ameliorating the effects of asthma and allergies; improving energy; improving insulin secretion; decreasing kidney stone accumulation; alleviating the effects of gout; minimizing convulsions related to epilepsy and other seizure disorders; and providing palliative effects to those addicted to drugs.
摘要翻译：用于抑制某些酶的方法和组合物，其中这种抑制作用提供了各种健康益处。更具体地，使用以下一种或多种的方法和组合：非叶提取物; 诺丽叶汁和/或烤叶抑制以下：HMG-CoA还原酶; 磷酸二酯酶（3和4）PDE3和PDE4; 5 -Lipoxygenase（LOX）和15-LOX; 黄嘌呤氧化酶（XO）; 提供γ-氨基丁酸（GABA）和第二常见的人类皮肤癌细胞系的生长。此外，上述酶抑制导致：缓解疼痛和炎症; 治疗前列腺癌; 降低胆固醇水平; 抵制糖尿病II型; 维持脑中细胞相互作用的最高可能完整性，导致不受干扰的神经功能（即神经保护）; 改善哮喘和过敏的作用; 改善能源; 改善胰岛素分泌; 减少肾结石积累; 减轻痛风的影响; 减少与癫痫和其他癫痫发作相关的惊厥; 并为吸毒成瘾者提供姑息治疗。

6. 发明申请

WO2011106432A3 MORINDA CITRIFOLIA AND IRIDOID BASED FORMULATIONS 审中-公开
标题翻译：基于摩尔多瓦和基于红薯的制剂
公开(公告)号：WO2011106432A3
公开(公告)日：2012-02-02
申请号：PCT/US2011025935
申请日：2011-02-23
申请人： TAHITIAN NONI INTERNATIONAL INC , WEST BRETT JUSTIN , JENSEN CLAUDE JARAKAE , PALU AFA KEHAATI , DENG SHIXIN , WASDEN JEFFREY A
发明人： WEST BRETT JUSTIN , JENSEN CLAUDE JARAKAE , PALU AFA KEHAATI , DENG SHIXIN , WASDEN JEFFREY A
IPC分类号： A23L33/00 , A23L2/38 , A23L2/56 , A23L2/58 , A23L2/66
CPC分类号： A61K36/746 , A61K2300/00
摘要： Embodiments of the invention relate to fortified food and dietary supplement products which may be administered to produce desirable physiological improvement. In particular, embodiments of the invention relates to the administration of products enhanced with Morinda citrifolia and iridoids.
摘要翻译：本发明的实施方案涉及可以施用以产生理想的生理学改善的强化食物和膳食补充剂产品。特别地，本发明的实施方案涉及对用Morinda citrifolia和环烯醚萜增强的产品的施用。

7. 发明申请

WO2005067489A2 TYPE II DIABETES 审中-公开
标题翻译： II型糖尿病
公开(公告)号：WO2005067489A2
公开(公告)日：2005-07-28
申请号：PCT/US2004042393
申请日：2004-12-17
申请人： SU CHEN , PALU AFA KEHAATI , ZHOU BING-NAN , JENSEN CLAUDE JARAKAE
发明人： SU CHEN , PALU AFA KEHAATI , ZHOU BING-NAN , JENSEN CLAUDE JARAKAE
IPC分类号： A23L1/30 , A23L2/02 , A23L2/04 , A61K31/353 , A61K31/7048 , A61K36/00 , A61K36/746
CPC分类号： A61K31/7048 , A23L2/02 , A23L2/04 , A23L33/105 , A61K31/353 , A61K36/746 , A61K2300/00
摘要： The present invention features a unique, natural formulation and method of administering the same to treat and prevent diabetes, or rather advances treatment of diabetes, by providing a nutraceutical composition or treatment formulated with one or more processed Morinda citrifolia products, including TAHITIAN NONI(R) juice and juice concentrate, as derived from the Indian Mulberry plant.
摘要翻译：本发明具有独特的天然配方和方法，通过提供一种或多种加工的Morinda citrifolia产品配制的营养组合物或治疗，包括TAHITIAN NONI（R ）果汁和果汁浓缩物，源自印度桑树植物。

8. 发明申请

WO2011106417A3 GARCINIA MANGOSTANA L. AND IRIDOID BASED FORMULATIONS 审中-公开
标题翻译： GARCINIA MANGOSTANA L.和IRIDOID的制剂
公开(公告)号：WO2011106417A3
公开(公告)日：2012-01-05
申请号：PCT/US2011025915
申请日：2011-02-23
申请人： TAHITIAN NONI INTERNATIONAL INC , WEST BRETT JUSTIN , JENSEN CLAUDE JARAKAE , PALU AFA KEHAATI , DENG SHIXIN , WASDEN JEFFREY A
发明人： WEST BRETT JUSTIN , JENSEN CLAUDE JARAKAE , PALU AFA KEHAATI , DENG SHIXIN , WASDEN JEFFREY A
IPC分类号： A23L33/00 , A23L19/00
CPC分类号： A61K31/352 , A23L2/02 , A23L2/52 , A23L33/10 , A23L33/105 , A23V2002/00 , A61K36/38 , A61K2300/00 , A23V2250/21 , A23V2200/02 , A23V2200/324
摘要： Embodiments of the invention relate to fortified food and dietary supplement products, which may be administered to produce desirable physiological improvement. In particular, embodiments of the invention relate to the administration of products enhanced with Garcinia mangostana L. and iridoids.
摘要翻译：本发明的实施方案涉及强化的食物和膳食补充剂产品，其可以被施用以产生期望的生理学改善。特别地，本发明的实施方案涉及用芒果加藤和环烯醚萜苷增强的产品的施用。

9. 发明申请

WO2011106423A3 ACAI AND IRIDOID BASED FORMULATIONS 审中-公开
标题翻译：基于ACAI和IRIDOID的制剂
公开(公告)号：WO2011106423A3
公开(公告)日：2012-01-05
申请号：PCT/US2011025923
申请日：2011-02-23
申请人： TAHITIAN NONI INTERNATIONAL INC , WEST BRETT JUSTIN , JENSEN CLAUDE JARAKAE , PALU AFA KEHAATI , DENG SHIXIN , WASDEN JEFFREY A
发明人： WEST BRETT JUSTIN , JENSEN CLAUDE JARAKAE , PALU AFA KEHAATI , DENG SHIXIN , WASDEN JEFFREY A
IPC分类号： A23L1/29 , A23L1/30
CPC分类号： A61K36/889 , A23L33/105 , A23L33/15 , A61K31/7048 , A61K2300/00
摘要： Embodiments of the invention relate to fortified food and dietary supplement products, which may be administered to produce desirable physiological improvement. In particular, embodiments of the invention relate to the administration of products enhanced with Acai and iridoids.
摘要翻译：本发明的实施方案涉及强化的食物和膳食补充剂产品，其可以被施用以产生期望的生理学改善。特别地，本发明的实施方案涉及用Acai和环烯醚萜增强的产品的施用。

10. 发明申请

WO2007064547A3 MORINDA CITRIFOLIA BASED FORMULATION AND METHODS FOR WEIGHT MANAGEMENT 审中-公开
标题翻译： MORINDA CITRIFOLIA为基础的配方和体重管理方法
公开(公告)号：WO2007064547A3
公开(公告)日：2007-12-06
申请号：PCT/US2006045222
申请日：2006-11-22
申请人： TAHITIAN NONI INT INC , PALU AFA KEHAATI , ZHOU BING-NAN , WEST BRETT JUSTIN , JENSEN CLAUDE JARAKAE , STORY STEPHEN P
发明人： PALU AFA KEHAATI , ZHOU BING-NAN , WEST BRETT JUSTIN , JENSEN CLAUDE JARAKAE , STORY STEPHEN P
IPC分类号： A23L7/10 , A01N65/00
CPC分类号： A61K36/746 , A23L33/105 , A23V2002/00 , A61K36/45 , A61K36/73 , A61K36/87 , A61K2300/00 , A23V2250/21 , A23V2200/332
摘要： The present invention relates to weight management utilizing processed Morinda citrifolia products. Research supporting this invention indicates that processed Morinda citrifolia products may be used in weight management. The present invention is supported by research findings that suggest that oral administration of Morinda citrifolia can increase metabolic rate. An increased metabolic rate causes an individual to burn an increased amount of body fat. These observations are consistent with the concept that noni, can positively affect the regulation of excess body weight.
摘要翻译：本发明涉及利用加工的海巴戟天产物的体重管理。支持本发明的研究表明加工的海巴戟天产品可用于体重管理。本发明得到研究结果的支持，这表明口服海巴戟天可以提高代谢率。代谢率增加会导致个体燃烧体内脂肪量增加。这些观察结果与noni可以积极影响过量体重调节的概念是一致的。

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