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1. 发明申请

WO2022265694A1 ANTI-AGING DIETARY SUPPLEMENT 审中-公开
公开(公告)号：WO2022265694A1
公开(公告)日：2022-12-22
申请号：PCT/US2022/017557
申请日：2022-02-23
申请人： MORINDA, INC
发明人： WILLIS, Brent D. , SWARTZ, Fernando , PALU, Afa K. , WEST, Brett J.
IPC分类号： A23L33/105 , A23L33/15 , A23L33/16 , A23L33/175
摘要： The present invention relates to a formulation providing anti-aging benefits that may include ingredients from various ingredient groups such as amino acids, vitamins or mineral co-factors, antioxidants or carotenoids, an herbal, plant derivative, or phytonutrients, and other nutrients. When combined, these ingredients and, more specifically, the herbal, plant derivative, or phytonutrients blend provide increased and unexpected synergistic effects that inhibit DPP4 activity and provide anti-aging benefits.

2. 发明申请

WO2006050012A2 MORINDA CITRIFOLIA BASED COMPOSITIONS AND METHODS FOR INHIBITING XANTHINE OXIDASE 审中-公开
标题翻译：基于MORINDA CITRIFOLIA的组合物和抑制XANTHINE氧化酶的方法
公开(公告)号：WO2006050012A2
公开(公告)日：2006-05-11
申请号：PCT/US2005/038727
申请日：2005-10-26
申请人： MORINDA, INC.
发明人： PALU, Afa, Kehaati , SU, Chen , ZHOU, Bing-Nan , JENSEN, Claude, Jarakae , ASAY, Kim , STORY, Stephen, P.
IPC分类号： A61K36/45 , A61K36/73 , A61K36/746
CPC分类号： A61K36/73 , A61K36/45 , A61K36/746 , A61K2300/00
摘要： The present invention relates to the inhibition of xanthine oxidase. In particular, the present invention relates to systems and methods for utilizing Morinda citrifolia L. based compositions and methods to inhibit xanthine oxidase activity.
摘要翻译：本发明涉及黄嘌呤氧化酶的抑制。特别地，本发明涉及利用基于烟草柠檬酸的组合物和抑制黄嘌呤氧化酶活性的方法的系统和方法。

3. 发明申请

WO2005025410A3 FORMULATIONS AND METHODS FOR TREATING BREAST CANCER WITH MORINDA CITRIFOLIA AND METHYLSULFONYMETHANE 审中-公开
标题翻译：治疗乳腺癌与MORINDA CITRIFOLIA和甲基磺酰甲胺的制剂和方法
公开(公告)号：WO2005025410A3
公开(公告)日：2005-12-22
申请号：PCT/US2004029896
申请日：2004-09-10
申请人： MORINDA INC
发明人： WANG MIAN-YING , JENSEN CLAUDE JARAKAE , SU CHEN , STORY STEPHEN
IPC分类号： A23L1/30 , A61B20060101 , A61K31/10 , A61K36/746 , A61K35/78
CPC分类号： A61K31/10 , A23L33/10 , A23L33/105 , A23V2002/00 , A61K36/746 , A61K2300/00 , A23V2200/308 , A23V2250/21
摘要： The present invention advances prior art techniques, formulations, and methods for treating mammary breast cancer during its initial phases, as well as for preventing mammary breast cancer, by providing a safe, nutraceutical formulation comprising Morinda citrifolia, methylsulfonylmethane (MSM), and other ingredients.
摘要翻译：本发明通过提供一种安全的营养制剂，其包含柠檬酸海巴戟天，甲基磺酰甲烷（MSM）和其他成分，从而推进了在其初始阶段用于治疗乳腺癌的现有技术，制剂和方法，以及用于预防乳腺癌。

4. 发明申请

WO2002045654A3 CANCER PREVENTATIVE EFFECT OF MORINDA CITRIFOLIA 审中-公开
公开(公告)号：WO2002045654A3
公开(公告)日：2002-06-13
申请号：PCT/US2001/046835
申请日：2001-12-05
申请人： MORINDA, INC. , SU, Chen, Xing , JENSEN, Claud, Jarakae , STORY, Stephen, P. , WANG, Mian-Ying
发明人： SU, Chen, Xing , JENSEN, Claud, Jarakae , STORY, Stephen, P. , WANG, Mian-Ying
IPC分类号： A61K35/78
摘要： Providing and using a dietary supplement to inhibit cancer and/or to otherwise provide a cancer preventative effect at the initiation stage of carcinogenesis. The dietary supplement includes reconstituted Morinda citrifolia fruit juice from pure juice puree of French Polynesia, and may include other natural juices, such as a natural grape juice concentrate, natural blueberry juice concentrate, and/or another natural juice concentrate. The dietary supplement reduces the DMBA-DNA adduct formation in various organs, such as the heart, kidneys, lungs, and liver. The DNA adduct formation in various organs, such as the heart, kidneys, lungs, and liver. The DNA adduct formation furthers chemical carcinogenesis. The use of the dietary supplement protects cells and/or lipids from oxidative modification mediated by SAR. As such, the use of the dietary supplement contributes to cancer inhibitation.

5. 发明申请

WO2005091953A3 MORINDA CITRIFOLIA LEAF EXTRACT COMPOSITIONS AND METHODS OF OBTAINING THE SAME 审中-公开
标题翻译：茉莉花叶提取物组合物及其获得方法
公开(公告)号：WO2005091953A3
公开(公告)日：2007-04-12
申请号：PCT/US2005006923
申请日：2005-03-04
申请人： MORINDA INC , ZHOU BING-NAN , PALU AFA KEHAATI , SU CHEN , JENSEN CLAUDE JARAKAE , STORY STEPHEN
发明人： ZHOU BING-NAN , PALU AFA KEHAATI , SU CHEN , JENSEN CLAUDE JARAKAE , STORY STEPHEN
IPC分类号： A61K36/746 , A61K36/00
CPC分类号： A61K36/746
摘要： Methods and compositions relating to leaf extracts obtained from removing liquids from relatively dry Morinda citrifolia leaves. Methods and compositions relating to a leaf serum created from combining leaf extract and fruit juice from the Morinda citrifolia L. plant. Methods and compositions relating to leaf extract compositions comprising one or more of the leaf extracts and leaf serums.
摘要翻译：与从相对干燥的香茅草叶中除去液体获得的叶提取物相关的方法和组合物。与从叶片提取物和来自海巴戟天植物的果汁组合产生的叶片血清的方法和组合物。涉及包含一种或多种叶提取物和叶血清的叶提取物组合物的方法和组合物。

6. 发明申请

WO2005120538A1 MORINDA CITRIFOLIA-BASED FORMULATION 5-LOX AND 15-LOX 审中-公开
标题翻译：基于MORINDA CITRIFOLIA的配方5-LOX和15-LOX
公开(公告)号：WO2005120538A1
公开(公告)日：2005-12-22
申请号：PCT/US2004/019781
申请日：2004-06-18
申请人： MORINDA, INC.
发明人： PALU, Afa, Kehaati , ZHOU, Bing-Nan , SU, Chen , JENSEN, Claude, Jarakae , STORY, Stephen
IPC分类号： A61K35/78
CPC分类号： A23L2/02 , A23L33/105 , A61K36/746 , A61K2300/00
摘要： The present invention is directed to methods and formulations for inhibiting Lipoxygenase enzymes that function to biosynthesize or metabolize arachidonic acid into its intermediate Leukotriene constituents, as well as a method and formulation for treating and preventing diseases, including inflammatory diseases, and the symptoms associated with such diseases. The present invention methods and formulations effectively function as such through the introduction into the body (e.g. ingesting) a safe, pre-determined dosage of a naturaceutical composition formulated with or comprising one or more processed Morinda citrifolia products for a safe, predetermined duration, wherein the processed Morinda citrifolia product may comprise one or more isolated active ingredients.
摘要翻译：本发明涉及用于抑制作用于将花生四烯酸生物合成或代谢为其中间白细胞三烯成分的脂氧合酶的方法和制剂，以及用于治疗和预防包括炎性疾病在内的疾病的方法和制剂，以及与之相关的症状疾病。本发明的方法和制剂通过引入身体（例如摄入）安全，预定剂量的与一种或多种经加工的Morinda citrifolia产品配制或包含一种或多种加工的Morinda citrifolia产品的安全，预定的持续时间，有效地起作用，其中加工的Morinda citrifolia产品可以包含一种或多种分离的活性成分。

7. 发明申请

WO2005086937A3 METHODS AND COMPOSITIONS FOR INHIBITING MONOAMINE OXIDASE AND CATECHOL-L-METHYLTRANSFERASE 审中-公开
公开(公告)号：WO2005086937A3
公开(公告)日：2005-09-22
申请号：PCT/US2005/008069
申请日：2005-03-09
申请人： MORINDA, INC. , PALU, Afa, Kehaati , ZHOU, Bing-Nan , JENSEN, Claude, Jarakae , STORY, Stephen
发明人： PALU, Afa, Kehaati , ZHOU, Bing-Nan , JENSEN, Claude, Jarakae , STORY, Stephen
IPC分类号： A01N65/00
摘要： The present invention relates to methods and compositions for inhibiting Monoamine Oxidase and/or Catechol-O-Methyltransferase in living organisms. More particularly, the present invention relates to methods and compositions involving the inhibition of Monoamine Oxidase and/or Catechol-O-Methyltransferase using processed Morinda citrifolia L. plant products.

8. 发明申请

WO2002083159A1 PALLIATIVE EFFECTS OF MORINDA CITRIFOLIA OIL AND JUICE 审中-公开
标题翻译：茯苓油和果汁的诱导作用
公开(公告)号：WO2002083159A1
公开(公告)日：2002-10-24
申请号：PCT/US2002/012170
申请日：2002-04-17
申请人： MORINDA, INC.
发明人： JENSEN, Claude, Jarkae , MCPHILAMY, William , HALL, Steven, M. , SHARPS, Jim
IPC分类号： A61K35/78
CPC分类号： A61K36/746 , A23L33/105
摘要： A method of preventing and treating various ailments and diseases by utilizing the Cox-2 selective inhibition characteristics of processed Morinda citrifolia .
摘要翻译：通过利用加工的海巴戟天的Cox-2选择性抑制特性来预防和治疗各种疾病和疾病的方法。

9. 发明申请

WO0245654A2 CANCER PREVENTATIVE EFFECT OF MORINDA CITRIFOLIA 审中-公开
标题翻译：山药的抗癌作用
公开(公告)号：WO0245654A2
公开(公告)日：2002-06-13
申请号：PCT/US0146835
申请日：2001-12-05
申请人： MORINDA INC , SU CHEN XING , JENSEN CLAUD JARAKAE , STORY STEPHEN P
发明人： SU CHEN XING , JENSEN CLAUD JARAKAE , STORY STEPHEN P
IPC分类号： A23L1/30 , A23L2/02 , A61K36/60 , A61K36/746 , A61P35/00 , A61K
CPC分类号： A61K36/746 , A23L2/02 , A23L33/105 , A61K2300/00
摘要： Providing and using a dietary supplement to inhibit cancer and/or to otherwise provide a cancer preventative effect at the initiation stage of carcinogenesis. The dietary supplement includes reconstituted Morinda citrifolia fruit juice from pure juice puree of French Polynesia, and may include other natural juices, such as a natural grape juice concentrate, natural blueberry juice concentrate, and/or another natural juice concentrate. The dietary supplement reduces the DMBA-DNA adduct formation in various organs, such as the heart, kidneys, lungs, and liver. The DNA adduct formation in various organs, such as the heart, kidneys, lungs, and liver. The DNA adduct formation furthers chemical carcinogenesis. The use of the dietary supplement protects cells and/or lipids from oxidative modification mediated by SAR. As such, the use of the dietary supplement contributes to cancer inhibitation.
摘要翻译：提供和使用膳食补充剂来抑制癌症和/或以其他方式在癌发生的起始阶段提供癌症预防效果。膳食补充剂包括来自法属波利尼西亚纯果汁泥的复原海巴戟果汁，并且可以包括其他天然果汁，例如天然葡萄汁浓缩物，天然蓝莓汁浓缩物和/或另一种天然果汁浓缩物。膳食补充剂可减少各种器官（如心脏，肾脏，肺和肝脏）中DMBA-DNA加合物的形成。各种器官中的DNA加合物形成，如心脏，肾脏，肺和肝脏。 DNA加合物形成促进了化学致癌作用。膳食补充剂的使用保护细胞和/或脂质免于由SAR介导的氧化修饰。因此，使用膳食补充剂有助于抑制癌症。

10. 发明申请

WO2005048919A3 PREVENTATIVE EFFECTS OF MORINDA CITRIFOLIA ON MAMMARY BREAST CANCER 审中-公开
标题翻译：莫桑比卡因对乳腺癌的预防作用
公开(公告)号：WO2005048919A3
公开(公告)日：2005-08-11
申请号：PCT/US2004026253
申请日：2004-08-11
申请人： MORINDA INC
发明人： WANG MIAN-YING , JENSEN CLAUDE JARAKAE , SU CHEN
IPC分类号： A61K20060101 , A61K36/746 , A61K47/00
CPC分类号： A61K36/746
摘要： The present invention features a novel use of processed ingredients from the Indian mulberry plant. More specifically, the present invention features a novel use of processed Morinda citrifolia, namely Morinda citrifolia fruit juice, puree, or puree juice for treating breast cancer, and particularly for inhibiting and/or preventing the metastasis of carcinogenic cells within the mammary region of the breast, as well as destroying metastasized mammary or breast cancer cells. The present invention comprises the consumption of food products or medicinal products or compositions comprising processed Morinda citrifolia, in either puree or fruit juice form. The present invention also features a method of inhibiting carcinogen-mediated conversion of mammary cells and protecting DNA against carcinogen-mediated damage by administering a composition comprising water soluble Morinda citrifolia.
摘要翻译：本发明的特征在于印度桑植物的加工成分的新用途。更具体地，本发明的特征的新用途加工的海巴戟天的，即海巴戟天果汁，果泥，或泥汁用于治疗乳腺癌，并且特别为的乳房区域内抑制和/或预防致癌细胞的转移乳房，以及摧毁转移的乳腺癌或乳腺癌细胞。本发明包括食用产品或医药产品或包含处理过的海巴戟（Morinda citrifolia）的组合物，其呈果泥或果汁形式。本发明的特征还在于通过施用包含水溶性巴戟天的组合物来抑制致癌物介导的乳房细胞转化和保护DNA免于致癌物介导的损伤的方法。

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