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1. 发明申请

WO2007064521A3 MORINDA CITRIFOLIA LEAF JUICE AND LEAF EXTRACT BASED FORMULATIONS 审中-公开
标题翻译： MORINDA CITRIFOLIA LEAF JUICE和LEAF提取物制剂
公开(公告)号：WO2007064521A3
公开(公告)日：2010-02-18
申请号：PCT/US2006044949
申请日：2006-11-21
申请人： TAHITIAN NONI INT INC , PALU AFA KEHAATI , ZHOU BING-NAN , SU CHEN XING , JENSEN CLAUDE JARAKAE , WEST BRETT JUSTIN , STORY STEPHEN P
发明人： PALU AFA KEHAATI , ZHOU BING-NAN , SU CHEN XING , JENSEN CLAUDE JARAKAE , WEST BRETT JUSTIN , STORY STEPHEN P
IPC分类号： A61K36/746 , A61K36/00
CPC分类号： A61K36/746
摘要： A method and composition for inhibiting certain enzymes, where such inhibition results in various health benefits is provided. More particularly, a method and composition using one or more of the following: Noni Leaf Extract; Noni Leaf Juice; and/or Roast Leaf to inhibit the following: HMG-CoA Reductase; Phosphodiesterases (3 and 4) PDE3 and PDE4; 5 -Lipoxygenase (LOX) and 15-LOX; Xanthine Oxidase (XO); Gamma Amino Butyric Acid (GABA) and the growth of the second most common human skin cancer cell line, is provided. Moreover, the foregoing enzymatic inhibitions result in: alleviating pain and inflammation; treating prostate cancers; lowering cholesterol levels; counteracting Diabetes Type II; maintaining the highest possible integrity of cellular interactions in the brain resulting in an undisturbed neural function, (i.e., neuroprotection); ameliorating the effects of asthma and allergies; improving energy; improving insulin secretion; decreasing kidney stone accumulation; alleviating the effects of gout; minimizing convulsions related to epilepsy and other seizure disorders; and providing palliative effects to those addicted to drugs.
摘要翻译：用于抑制某些酶的方法和组合物，其中这种抑制作用提供了各种健康益处。更具体地，使用以下一种或多种的方法和组合：非叶提取物; 诺丽叶汁和/或烤叶抑制以下：HMG-CoA还原酶; 磷酸二酯酶（3和4）PDE3和PDE4; 5 -Lipoxygenase（LOX）和15-LOX; 黄嘌呤氧化酶（XO）; 提供γ-氨基丁酸（GABA）和第二常见的人类皮肤癌细胞系的生长。此外，上述酶抑制导致：缓解疼痛和炎症; 治疗前列腺癌; 降低胆固醇水平; 抵制糖尿病II型; 维持脑中细胞相互作用的最高可能完整性，导致不受干扰的神经功能（即神经保护）; 改善哮喘和过敏的作用; 改善能源; 改善胰岛素分泌; 减少肾结石积累; 减轻痛风的影响; 减少与癫痫和其他癫痫发作相关的惊厥; 并为吸毒成瘾者提供姑息治疗。

2. 发明申请

WO2009006565A3 FORMULATIONS AND METHODS FOR INHIBITING ANAEROBES, GRAM NEGATIVE BACTERIA, PROTOZOA AND OTHER MICROBIAL GROWTH WITH MORINDA CITRIFOLIA L. ENHANCED FORMULATIONS 审中-公开
标题翻译：强化制剂抑制厌氧菌，革兰氏阴性细菌，原生动物和其他微生物生长的制剂和方法
公开(公告)号：WO2009006565A3
公开(公告)日：2009-03-12
申请号：PCT/US2008069136
申请日：2008-07-03
申请人： TAHITIAN NONI INT INC , KEHAATI AFA PALU , WEST BRETT JUSTIN , JENSEN CLAUDE JARAKAE
发明人： KEHAATI AFA PALU , WEST BRETT JUSTIN , JENSEN CLAUDE JARAKAE
IPC分类号： A61K36/746
CPC分类号： A01N65/00 , A01N65/08 , A61K9/14 , A61K36/746 , A01N25/26 , A01N43/16
摘要： The invention relates to the administration of products enhanced with Morinda citrifolia L. in order to inhibit anaerobes, gram negative bacteria, protozoa and other microbial growth related to various maladies and illnesses which result in detrimental physiological effects.
摘要翻译：本发明涉及施用用海巴戟增强的产品以抑制与各种疾病和疾病有关的厌氧菌，革兰氏阴性菌，原生动物和其他微生物生长，这些疾病导致有害的生理效应。

3. 发明申请

WO2007134205A8 METHOD AND COMPOSITION FOR ADMINISTERING BIOACTIVE COMPOUNDS DERIVED FROM MORINDA CITRIFOLIA 审中-公开
标题翻译：用于管理从木霉菌衍生的生物活性化合物的方法和组合物
公开(公告)号：WO2007134205A8
公开(公告)日：2008-01-10
申请号：PCT/US2007068729
申请日：2007-05-11
申请人： TAHITIAN NONI INT INC , ZHOU BING-NAN , SU CHEN , PALU AFA K , WEST BRETT J , DENG SHIXIN , JENSEN CLAUDE JARAKAE , STORY STEPHEN
发明人： ZHOU BING-NAN , SU CHEN , PALU AFA K , WEST BRETT J , DENG SHIXIN , JENSEN CLAUDE JARAKAE , STORY STEPHEN
IPC分类号： A01N65/00 , A61K36/00
CPC分类号： A61K36/746
摘要： This invention relates to a method and composition for providing in various health benefits by administering various bioactive compounds derived from the plant Morinda cirtrifolia to individuals. This invention relates to using one or more of the following: Noni Leaf Extract; Noni Leaf Juice; and/or Roast Leaf. More particularly this invention relates to administering one or more of the following: Pyro-phorbide a, Pheophorbide a, Purpin 7, and/or Pheophorbide all which may be derived from Noni leaf extract, Noni leaf juice, and/or Roast leaf. Moreover, the foregoing formulations result in alleviating pain and inflammation.
摘要翻译：本发明涉及通过向个体施用衍生自植物Morinda cirtrifolia的各种生物活性化合物来提供各种健康益处的方法和组合物。本发明涉及使用以下一种或多种：非叶提取物; 诺丽叶汁和/或烤叶。更具体地说，本发明涉及施用一种或多种以下物质：可以衍生自Noni叶提取物，Noni叶汁和/或Rost叶的Pyro-Phorbide a，Pheophorbide a，Purpin 7和/或Pheororbide all。此外，上述制剂导致减轻疼痛和炎症。

4. 发明申请

WO2007064607A3 FORMULATION AND METHODS FOR USE OF MORINDA CITRIFOLIA SEED OIL 审中-公开
公开(公告)号：WO2007064607A3
公开(公告)日：2007-06-07
申请号：PCT/US2006/045455
申请日：2006-11-27
申请人： TAHITIAN NONI INTERNATIONAL, INC. , PALU, Afa, Kehaati , ZHOU, Bing-nan , WEST, Brett, Justin , JENSEN, Claude, Jarakae , STORY, Stephen, P.
发明人： PALU, Afa, Kehaati , ZHOU, Bing-nan , WEST, Brett, Justin , JENSEN, Claude, Jarakae , STORY, Stephen, P.
IPC分类号： A61K36/00
摘要： The present invention relates to nutraceutical formulations and methods for use of fetid oil derived from Morinda citrifolia seeds. Research supporting this invention indicates that processed Morinda citrifolia seed products may be used for weight management and health promotion. The present invention is supported by research findings related to the nutritional benefits of fetid oil extracted from the seeds contained within Morinda citrifolia fruit. This oil has been found to include high concentrations of linoleic acid, which is known to increase metabolic rate, help prevent cancer, protect the liver, and help prevent the build up of artery plaque. These observations are consistent with the concept that noni, can positively affect the regulation of excess body weight and promote overall good health.

5. 发明申请

WO2007064547A2 MORINDA CITRIFOLIA BASED FORMULATION AND METHODS FOR WEIGHT MANAGEMENT 审中-公开
标题翻译：基于MORINDA CITRIFOLIA的制定方法和重量管理方法
公开(公告)号：WO2007064547A2
公开(公告)日：2007-06-07
申请号：PCT/US2006/045222
申请日：2006-11-22
申请人： TAHITIAN NONI INTERNATIONAL, INC. , PALU, Afa, Kehaati , ZHOU, Bing-Nan , WEST, Brett, Justin , JENSEN, Claude, Jarakae , STORY, Stephen, P.
发明人： PALU, Afa, Kehaati , ZHOU, Bing-Nan , WEST, Brett, Justin , JENSEN, Claude, Jarakae , STORY, Stephen, P.
IPC分类号： A61K36/746
CPC分类号： A61K36/746 , A23L33/105 , A23V2002/00 , A61K36/45 , A61K36/73 , A61K36/87 , A61K2300/00 , A23V2250/21 , A23V2200/332
摘要： The present invention relates to weight management utilizing processed Morinda citrifolia products. Research supporting this invention indicates that processed Morinda citrifolia products may be used in weight management. The present invention is supported by research findings that suggest that oral administration of Morinda citrifolia can increase metabolic rate. An increased metabolic rate causes an individual to burn an increased amount of body fat. These observations are consistent with the concept that noni, can positively affect the regulation of excess body weight.
摘要翻译：本发明涉及使用加工的海巴戟天产品的重量管理。支持本发明的研究表明，加工的海伦达柠檬酸产品可用于体重管理。本发明得到研究结果的支持，表明口服Morinda citrifolia可以增加代谢率。增加的代谢率导致个体燃烧身体脂肪增加。这些观察结果与noni可以积极影响过量体重调节的概念一致。

6. 发明申请

WO2011106432A3 MORINDA CITRIFOLIA AND IRIDOID BASED FORMULATIONS 审中-公开
标题翻译：基于摩尔多瓦和基于红薯的制剂
公开(公告)号：WO2011106432A3
公开(公告)日：2012-02-02
申请号：PCT/US2011025935
申请日：2011-02-23
申请人： TAHITIAN NONI INTERNATIONAL INC , WEST BRETT JUSTIN , JENSEN CLAUDE JARAKAE , PALU AFA KEHAATI , DENG SHIXIN , WASDEN JEFFREY A
发明人： WEST BRETT JUSTIN , JENSEN CLAUDE JARAKAE , PALU AFA KEHAATI , DENG SHIXIN , WASDEN JEFFREY A
IPC分类号： A23L33/00 , A23L2/38 , A23L2/56 , A23L2/58 , A23L2/66
CPC分类号： A61K36/746 , A61K2300/00
摘要： Embodiments of the invention relate to fortified food and dietary supplement products which may be administered to produce desirable physiological improvement. In particular, embodiments of the invention relates to the administration of products enhanced with Morinda citrifolia and iridoids.
摘要翻译：本发明的实施方案涉及可以施用以产生理想的生理学改善的强化食物和膳食补充剂产品。特别地，本发明的实施方案涉及对用Morinda citrifolia和环烯醚萜增强的产品的施用。

7. 发明申请

WO2011106448A3 IRIDOID BASED FORMULATIONS 审中-公开
标题翻译：胭脂虫基制剂
公开(公告)号：WO2011106448A3
公开(公告)日：2011-09-01
申请号：PCT/US2011/025951
申请日：2011-02-23
申请人： TAHITIAN NONI INTERNATIONAL, INC. , WEST, Brett, Justin , JENSEN, Claude, Jarakae , PALU, Afa, Kehaati , DENG, Shixin , WASDEN, Jeffrey, A.
发明人： WEST, Brett, Justin , JENSEN, Claude, Jarakae , PALU, Afa, Kehaati , DENG, Shixin , WASDEN, Jeffrey, A.
IPC分类号： A23L1/29 , A23L2/38 , A23L2/56 , A23L2/58 , A23L2/60
摘要： Embodiments of the invention relate to fortified food and dietary supplement products which may be administered to produce desirable physiological improvement. In particular, embodiments of the invention relates to the administration of products enhanced with plant products and iridoids.
摘要翻译：本发明的实施方案涉及可以施用以产生期望的生理改善的强化食品和膳食补充剂产品。特别地，本发明的实施方案涉及施用用植物产品和环烯醚萜增强的产品。

8. 发明申请

WO2011106423A2 ACAI AND IRIDOID BASED FORMULATIONS 审中-公开
标题翻译：基于ACAI和IRIDOID的制剂
公开(公告)号：WO2011106423A2
公开(公告)日：2011-09-01
申请号：PCT/US2011/025923
申请日：2011-02-23
申请人： TAHITIAN NONI INTERNATIONAL, INC. , WEST, Brett Justin , JENSEN, Claude Jarakae , PALU, Afa Kehaati , DENG, Shixin , WASDEN, Jeffrey A.
发明人： WEST, Brett Justin , JENSEN, Claude Jarakae , PALU, Afa Kehaati , DENG, Shixin , WASDEN, Jeffrey A.
IPC分类号： A23L1/29 , A23L1/30
CPC分类号： A61K36/889 , A23L33/105 , A23L33/15 , A61K31/7048 , Y02A50/409 , A61K2300/00
摘要： Embodiments of the invention relate to fortified food and dietary supplement products, which may be administered to produce desirable physiological improvement. In particular, embodiments of the invention relate to the administration of products enhanced with Acai and iridoids.
摘要翻译：本发明的实施方案涉及强化的食物和膳食补充剂产品，其可以被施用以产生期望的生理学改善。特别地，本发明的实施方案涉及用Acai和环烯醚萜苷增强的产品的施用。

9. 发明申请

WO2008067410A3 LIPOXYGENASE AND CYCLOOXYGENASE INHIBITION 审中-公开
标题翻译： LIPOXYGENASE和CYCLOOXYGENASE抑制
公开(公告)号：WO2008067410A3
公开(公告)日：2008-12-04
申请号：PCT/US2007085804
申请日：2007-11-28
申请人： TAHITIAN NONI INT INC , DENG SHIXIN , WEST BRETT , PALU AFA , SU CHEN , ZHOU BING-NAN , JENSEN JARAKAE
发明人： DENG SHIXIN , WEST BRETT , PALU AFA , SU CHEN , ZHOU BING-NAN , JENSEN JARAKAE
IPC分类号： A61K36/00
CPC分类号： A61K36/746
摘要： The present invention relates to methods, compositions and their constituents for inhibiting 5-Lipoxygenase (5-LO), 15 -Lipoxygenase (15-LO), cyclooxygenase-1 (COX-I) and cyclooxygenase-2 (COX-2), in living organisms. More particularly, the present invention relates to methods and compositions involving the inhibition of 5- Lipoxygenase (5-LO), 15-Lipoxygenase (15-LO), cyclooxygenase-1 (COX-I) and cyclooxygenase-2 (COX-2), using processed Morinda citrifolia L. plant products.
摘要翻译：本发明涉及用于抑制5-脂氧合酶（5-LO），15-加氧酶（15-LO），环加氧酶-1（COX-1）和环加氧酶-2（COX-2）的方法，组合物及其成分生物体。更具体地说，本发明涉及涉及抑制5-脂氧合酶（5-LO），15-脂氧合酶（15-LO），环加氧酶-1（COX-1）和环氧合酶-2（COX-2）的方法和组合物，，使用加工的Morinda citrifolia L.植物产品。

10. 发明申请

WO2008067410A2 LIPOXYGENASE AND CYCLOOXYGENASE INHIBITION 审中-公开
标题翻译：脂氧合酶和环加氧酶抑制
公开(公告)号：WO2008067410A2
公开(公告)日：2008-06-05
申请号：PCT/US2007/085804
申请日：2007-11-28
申请人： TAHITIAN NONI INTERNATIONAL, INC. , DENG, Shixin , WEST, Brett , PALU, Afa , SU, Chen , ZHOU, Bing-nan , JENSEN, Jarakae
发明人： DENG, Shixin , WEST, Brett , PALU, Afa , SU, Chen , ZHOU, Bing-nan , JENSEN, Jarakae
IPC分类号： A61K36/746
CPC分类号： A61K36/746
摘要： The present invention relates to methods, compositions and their constituents for inhibiting 5-Lipoxygenase (5-LO), 15 -Lipoxygenase (15-LO), cyclooxygenase-1 (COX-I) and cyclooxygenase-2 (COX-2), in living organisms. More particularly, the present invention relates to methods and compositions involving the inhibition of 5- Lipoxygenase (5-LO), 15-Lipoxygenase (15-LO), cyclooxygenase-1 (COX-I) and cyclooxygenase-2 (COX-2), using processed Morinda citrifolia L. plant products.
摘要翻译：本发明涉及用于抑制5-脂肪氧合酶（5-LO），15-脂氧合酶（15-LO），环氧合酶-1（COX-1）和环加氧酶-2的方法，组合物及其组分。 2（COX-2），在生物体内。更具体地说，本发明涉及涉及抑制5-脂氧合酶（5-LO），15-脂氧化酶（15-LO），环氧合酶-1（COX-1）和环氧合酶-2（COX-2）的方法和组合物。，使用加工的巴戟天属植物产品。

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