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    • 1. 发明申请
    • SELECTIVELY INHIBITING ESTROGEN PRODUCTION AND PROVIDING ESTROGENIC EFFECTS IN THE HUMAN BODY
    • 选择性抑制雌激素在人体内的生产和提供雌激素作用
    • WO2004091545A2
    • 2004-10-28
    • PCT/US2004009129
    • 2004-03-25
    • MORINDA INCPALU AFA KEHAATI
    • PALU AFA KEHAATIWANG MIAN YINGSU CHEN XINGWEST BRETT JUSTINWESTENDORF JOHANNES JOSEPHJENSEN CLAUDE JARAKAESTORY STEPHEN PAUL
    • A61K31/353A61K36/00A61K36/746A61K
    • A61K36/746A61K31/353
    • Implementation is directed to selectively inhibiting estrogen production and providing estrogenic effects in a human body. A dietary supplement includes a processed Morinda citrifolia product that is used to inhibit aromatase or aromatase enzymes that function to convert androgens to estrogens, inhibit receptors from binding with estrogen, and reduce and/or regulate estrogen production, as well as reduce the amount of estrogen produced within the body and regulating such production. The dietary supplement further provides estrogenic effects. The present invention methods and compositions effectively function to treat estrogen-dependent cancers, and particularly inhibit, destroy, and reverse the effects of of estrogen­dependent cancerous tumors through the introduction into the body (e.g. ingesting) a safe, pre-determined dosage of a naturaceutical composition formulated with or comprising one or more processed Morinda citrifolia products for a safe, pre­determined duration.
    • 实施的目的是选择性地抑制雌激素产生并在人体内提供雌激素作用。 膳食补充剂包括加工的Morinda citrifolia产品,其用于抑制将雄激素转化成雌激素,抑制受体与雌激素结合的芳香酶或芳香酶,以及减少和/或调节雌激素的产生以及减少雌激素的量 在体内生产并调节这种生产。 膳食补充剂进一步提供雌激素作用。 本发明的方法和组合物有效地用于治疗雌激素依赖性癌症,特别是抑制,破坏和逆转雌激素依赖性癌性肿瘤的作用通过引入体内(例如摄取)安全的预定剂量的药物 配制或包含一种或多种加工的Morinda citrifolia产品的组合物用于安全的,预定的持续时间。