专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2015148344A2 TRKA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF 审中-公开
标题翻译： TRKA激酶抑制剂，其组合物及其方法
公开(公告)号：WO2015148344A2
公开(公告)日：2015-10-01
申请号：PCT/US2015021936
申请日：2015-03-23
申请人： MERCK SHARP & DOHME , MSD R & D CHINA CO LTD , MITCHELL HELEN , FRALEY MARK E , COOKE ANDREW J , CHEN YI-HENG , STUMP CRAIG A , ZHANG XU-FANG , MCCOMAS CASEY C , SCHIRRIPA KATHY , MCWHERTER MELODY , MERCER SWATI P , BABAOGLU KERIM , MENG DONGFANG , WU JANE , LIU PING , WOOD HAROLD B , BAO JIANMING , LI CHUN SING , MAO QINGHUA , QI ZHIQI
发明人： MITCHELL HELEN , FRALEY MARK E , COOKE ANDREW J , CHEN YI-HENG , STUMP CRAIG A , ZHANG XU-FANG , MCCOMAS CASEY C , SCHIRRIPA KATHY , MCWHERTER MELODY , MERCER SWATI P , BABAOGLU KERIM , MENG DONGFANG , WU JANE , LIU PING , WOOD HAROLD B , BAO JIANMING , LI CHUN SING , MAO QINGHUA , QI ZHIQI
IPC分类号： C07D471/04
CPC分类号： C07D491/107 , C07C233/66 , C07D213/75 , C07D231/12 , C07D239/42 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04
摘要： The present invention is directed to six membered heteroaryl benzamide compounds of formula (I), which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence are useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor TrkA.
摘要翻译：本发明涉及式（I）的六元杂芳基苯甲酰胺化合物，其为原肌球蛋白相关激酶（Trk）家族蛋白激酶抑制剂，因此可用于治疗疼痛，炎症，癌症，再狭窄，动脉粥样硬化，牛皮癣，血栓形成，疾病，障碍，损伤或与神经生长因子（NGF）受体TrkA的异常活动相关的疾病或病症相关的异常髓鞘或脱髓鞘相关的功能障碍。

2. 发明申请

WO2015148373A3 TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF 审中-公开
公开(公告)号：WO2015148373A3
公开(公告)日：2015-11-26
申请号：PCT/US2015022004
申请日：2015-03-23
申请人： MERCK SHARP & DOHME , MITCHELL HELEN , FRALEY MARK E , COOKE ANDREW J , STUMP CRAIG A , CHEN YI HENG , BESHORE DOUGLAS C , ZHANG XU-FANG , MCCOMAS CASEY C , SCHIRRIPA KATHY , MCWHERTER MELODY , MERCER SWATI P , MOORE KEITH P , LIU PING , WOOD HAROLD B , LI CHUN SING , MAO QINGHUA
发明人： MITCHELL HELEN , FRALEY MARK E , COOKE ANDREW J , STUMP CRAIG A , CHEN YI HENG , BESHORE DOUGLAS C , ZHANG XU-FANG , MCCOMAS CASEY C , SCHIRRIPA KATHY , MCWHERTER MELODY , MERCER SWATI P , MOORE KEITH P , LIU PING , WOOD HAROLD B , LI CHUN SING , MAO QINGHUA
IPC分类号： A61K31/166
CPC分类号： C07D403/12 , C07D401/12 , C07D403/14 , C07D471/04 , C07D487/04 , C07D513/04
摘要： The present invention is directed to a bicyclic heteroaryl benzamide compounds of formula (I) which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence are useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor TrkA.

3. 发明申请

WO2015148350A3 TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF 审中-公开
标题翻译： TrkA激酶抑制剂，其组合物及其方法
公开(公告)号：WO2015148350A3
公开(公告)日：2015-11-26
申请号：PCT/US2015021944
申请日：2015-03-23
申请人： MERCK SHARP & DOHME , MITCHELL HELEN , FRALEY MARK E , COOKE ANDREW J , STUMP CRAIG A , ZHANG XU-FANG , MCCOMAS CASEY C , SCHIRRIPA KATHY , MCWHERTER MELODY , LIU PING , PARKER DANN , LI CHUN SING , MAO QINGHUA
发明人： MITCHELL HELEN , FRALEY MARK E , COOKE ANDREW J , STUMP CRAIG A , ZHANG XU-FANG , MCCOMAS CASEY C , SCHIRRIPA KATHY , MCWHERTER MELODY , LIU PING , PARKER DANN , LI CHUN SING , MAO QINGHUA
IPC分类号： A61K31/166
CPC分类号： C07D487/04 , C07D231/40 , C07D277/46 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D403/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04
摘要： The present invention is directed to substituted five membered heteroaryl benzamide compounds of formula (I) (Formula (I)) which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence are useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor TrkA.
摘要翻译：本发明涉及作为原肌球蛋白相关激酶（Trk）家族蛋白激酶抑制剂的式（I）（式（I））的取代的五元杂芳基苯甲酰胺化合物，因此可用于治疗疼痛，炎症，癌症，再狭窄，动脉粥样硬化，牛皮癣，血栓形成，疾病，障碍，损伤或与神经生长因子（NGF）受体TrkA的异常活动相关的疾病或病症相关的异常髓鞘或脱髓鞘的功能障碍。

4. 发明申请

WO2016164286A3 TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF 审中-公开
标题翻译： TrkA激酶抑制剂，其组合物及其方法
公开(公告)号：WO2016164286A3
公开(公告)日：2017-01-05
申请号：PCT/US2016025810
申请日：2016-04-04
申请人： MERCK SHARP & DOHME , STUMP CRAIG A , CHEN YI HENG , LIU PING , MENG DONGFANG , WU JANE , LI CHUN SING , QI ZHIQI
发明人： STUMP CRAIG A , CHEN YI HENG , LIU PING , MENG DONGFANG , WU JANE , LI CHUN SING , QI ZHIQI
IPC分类号： A61K31/166 , A61K31/437 , C07D471/04
CPC分类号： C07D417/12 , C07D403/12 , C07D471/04 , C07D473/04
摘要： The present invention is directed to bicyclic heteroaryl benzamide compounds of formulas (I): which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence are useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor TrkA.
摘要翻译：本发明涉及式（I）的双环杂芳基苯甲酰胺化合物：其为原肌球蛋白相关激酶（Trk）家族蛋白激酶抑制剂，因此可用于治疗疼痛，炎症，癌症，再狭窄，动脉粥样硬化，牛皮癣，与神经生长因子（NGF）受体TrkA的异常活动相关的血栓形成，疾病，障碍，损伤或与脱髓鞘或脱髓鞘相关的疾病或障碍。

5. 发明申请

WO2006041797A2 ACYCLIC HYDRAZIDES AS CANNABINOID RECEPTOR MODULATORS 审中-公开
标题翻译：无环肼类化合物作为CANNABINOID受体调节剂
公开(公告)号：WO2006041797A2
公开(公告)日：2006-04-20
申请号：PCT/US2005035560
申请日：2005-10-03
申请人： MERCK & CO INC , LIN LINUS S , LIU PING
发明人： LIN LINUS S , LIU PING
IPC分类号： A61K31/16
CPC分类号： C07C255/66 , C07C243/28 , C07C243/32 , C07C243/36 , C07C2601/08 , C07D213/64
摘要： The acyclic hydrazides of the invention are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. The compounds of the present invention are useful as centrally acting drugs in the treatment of psychosis, memory deficits, cognitive disorders, migraine, neuropathy, neuro-inflammatory disorders including multiple sclerosis and Guillain-Barre syndrome and the inflammatory sequelae of viral encephalitis, cerebral vascular accidents, and head trauma, anxiety disorders, stress, epilepsy, Parkinson's disease, movement disorders, and schizophrenia. The compounds are also useful for the treatment of substance abuse disorders (including smoking cessation), the treatment of obesity or eating disorders, as well as the treatment of asthma, constipation, chronic intestinal pseudo-obstruction, and cirrhosis of the liver.
摘要翻译：本发明的无环酰肼是大麻素-1（CB1）受体的拮抗剂和/或反激动剂，并且可用于治疗，预防和抑制由CB1受体介导的疾病。本发明化合物可用作治疗精神病，记忆缺陷，认知障碍，偏头痛，神经病，包括多发性硬化症和格林 - 巴利综合征的神经炎症和病毒性脑炎的炎性后遗症，脑血管障碍事故和头部创伤，焦虑症，压力，癫痫，帕金森病，运动障碍和精神分裂症。该化合物还可用于治疗药物滥用障碍（包括戒烟），治疗肥胖或进食障碍，以及治疗哮喘，便秘，慢性肠假性梗阻和肝硬化。

6. 发明申请

WO0186265A3 H02 DOPED W03, ULTRA-FAST, HIGH-SENSITIVE HYDROGEN SENSORS 审中-公开
标题翻译： H02 DOPED W03，超快速，高灵敏度的传感器
公开(公告)号：WO0186265A3
公开(公告)日：2002-07-18
申请号：PCT/US0114375
申请日：2001-05-05
申请人： MIDWEST RESEARCH INST , LIU PING , TRACY C EDWIN , PITTS J ROLAND , LEE SE-HEE
发明人： LIU PING , TRACY C EDWIN , PITTS J ROLAND , LEE SE-HEE
IPC分类号： G01N21/78 , G01N33/00 , C23C14/00
CPC分类号： G01N21/783 , G01N33/005 , Y10T436/22
摘要： An ultra-fast response, high sensitivity structure for optical detection of low concentrations of hydrogen gas, comprising: a substrate; a water-doped WO3 layer coated on the substrate; and a palladium layer coated on the water-doped WO3 layer.
摘要翻译：用于低浓度氢气的光学检测的超快响应，高灵敏度结构，包括：基底; 涂覆在基材上的掺水WO3层; 以及涂覆在掺水WO3层上的钯层。

7. 发明申请

WO0172052A2 METHOD AND APPARATUS FOR PARALLEL MULTI-VIEWPOINT VIDEO CAPTURING AND COMPRESSION 审中-公开
标题翻译：用于并行多视点视频捕获和压缩的方法和装置
公开(公告)号：WO0172052A2
公开(公告)日：2001-09-27
申请号：PCT/IB0100676
申请日：2001-03-23
申请人： REALITY COMMERCE CORP , LIU PING
发明人： LIU PING
IPC分类号： H04N7/50 , H04N13/02 , H04N13/00
CPC分类号： H04N5/2627 , H04N19/61
摘要： A method and apparatus for digital video capturing and compression supports multi-viewpoint interactive video applications. Multiple (typically hundreds of) video cameras centripetally placed in a three dimensional space acquire real-time visual pictures of the same 3D scene from multiple viewpoints at the rate of 20 &tilde& 30 frames per second (fps). Parallel Multi-Viewpoint Video Capturing and Compression (PMVCC) supports the operation of the apparatus. In an exemplary realization, a Multi-DSP Array (MDA) architecture uses hundreds of high-performance digital signal processors (DSPs) working in parallel to obtain a sustained computation power of hundreds of GIPS (Giga Instructions Per Second).
摘要翻译：用于数字视频捕获和压缩的方法和装置支持多视点交互式视频应用。向心地放置在三维空间中的多个（通常为数百个）摄像机以20和30帧/秒（fps）的速率从多个视点获取同一3D场景的实时视觉图像。并行多视点视频捕获和压缩（PMVCC）支持设备的操作。在示例性实现中，多DSP阵列（MDA）架构使用数百个并行工作的高性能数字信号处理器（DSP）来获得数百个GIPS（Giga Instruction Per Second）的持续计算能力。

8. 发明申请

WO2008131132B1 CAPTURE OF CARBON DIOXIDE (CO2) FROM AIR 审中-公开
标题翻译：二氧化碳（CO2）从空气中捕获
公开(公告)号：WO2008131132B1
公开(公告)日：2008-12-18
申请号：PCT/US2008060672
申请日：2008-04-17
申请人： GLOBAL RES TECHNOLOGIES LLC , WRIGHT ALLEN B , LACKNER KLAUS S , LEON-GUERRERO ED , GINSTER URSULA , CATTERSON TYMOTHY , MADISON KARL , ISHIKAWA RYUHEI , GRIMM GEORGE , MALCOMSON MARK , LIU PING
发明人： WRIGHT ALLEN B , LACKNER KLAUS S , LEON-GUERRERO ED , GINSTER URSULA , CATTERSON TYMOTHY , MADISON KARL , ISHIKAWA RYUHEI , GRIMM GEORGE , MALCOMSON MARK , LIU PING
IPC分类号： B01D53/02
CPC分类号： B01D53/025 , B01D53/04 , B01D2253/202 , B01D2253/206 , B01D2257/504 , B01D2259/40083 , Y02C10/04 , Y02C10/06 , Y02C10/08
摘要： Disclosed is a method for removing carbon dioxide from a gas stream, comprising placing the gas stream in contact with a resin, wetting the resin with water, collecting water vapor and carbon dioxide from the resin, and separating the carbon dioxide from the water vapor. The resin may be placed in a chamber or a plurality of chambers connected in series wherein the first chamber contains resin that was first contacted by the gas, and each successive chamber contains resin which has been wetted and carbon dioxide collected from for a greater period of time than the previous chamber, and so on, until the last chamber. Secondary sorbents may be employed to further separate the carbon dioxide from the water vapor.
摘要翻译：公开了一种从气流中除去二氧化碳的方法，包括将气流与树脂接触，用水润湿树脂，从树脂中收集水蒸气和二氧化碳，并将二氧化碳与水蒸气分离。树脂可以放置在串联连接的室或多个室中，其中第一室包含首先与气体接触的树脂，并且每个相继的室含有已经润湿的树脂和从更长时间内收集二氧化碳时间比以前的房间，等等，直到最后一个房间。二次吸附剂可用于进一步将二氧化碳与水蒸气分离。

9. 发明申请

WO2005029552A3 SN-C STRUCTURES PREPARED BY PLASMA-ENHANCED CHEMICAL VAPOR DEPOSITION 审中-公开
标题翻译：通过等离子增强化学气相沉积制备的SN-C结构
公开(公告)号：WO2005029552A3
公开(公告)日：2005-09-09
申请号：PCT/US2004030371
申请日：2004-09-16
申请人： MIDWEST RESEARCH INST , LIU PING , TURNER JOHN A
发明人： LIU PING , TURNER JOHN A
IPC分类号： C01B31/30 , H01L20060101
CPC分类号： C23C16/32 , B22F2998/00 , C22C13/00 , H01M4/0428 , H01M4/1395 , H01M4/38 , H01M4/58 , H01M10/052 , Y02T10/7011 , B22F9/30 , B22F2202/13
摘要： An exemplary depositing method includes use of a plasma-enhanced chemical vapor depostion (PECVD) technique to deposit various exemplary tin and carbon compositions onto a surface. Such compositions are optionally suitable for use as anodes for lithium-ion batteries. Method parameters such as electromagnetic energy or power and temperature (e.g., substrate temperature, etc.) can affect characteristics of deposited compositions. Various exemplary compositions allow for interaction between tin and lithium and carbon and lithium to thereby increase lithium storage capacity. Various exemplary compositions exhibit superior long term cycling stability and are suitable for use as an anode or an anode material.
摘要翻译：示例性沉积方法包括使用等离子体增强化学气相沉积（PECVD）技术将各种示例性锡和碳组合物沉积到表面上。这种组合物任选适合用作锂离子电池的阳极。诸如电磁能或功率和温度（例如，衬底温度等）的方法参数可影响沉积的组合物的特性。各种示例性组合物允许锡和锂以及碳和锂之间的相互作用，从而增加锂储存容量。各种示例性组合物表现出优异的长期循环稳定性并且适合用作阳极或阳极材料。

10. 发明申请

WO2004102820A2 PEAK CURRENT CONTROL IN WIRELESS NETWORK INTERFACE DEVICES 审中-公开
标题翻译：无线网络接口设备中的峰值电流控制
公开(公告)号：WO2004102820A2
公开(公告)日：2004-11-25
申请号：PCT/CA2004000733
申请日：2004-05-14
申请人： SIERRA WIRELESS INC , LIU PING , MILLER BRUCE , WONG RACHEL
发明人： LIU PING , MILLER BRUCE , WONG RACHEL
IPC分类号： H04B1/04 , H04B1/38 , H04B1/16
CPC分类号： H04B1/38 , H04B2001/0416
摘要： Methods of and apparatuses for varying and controlling the efective series resistance (ESR) of a power supply rail configured to transmit power from a power supply of a host device to a wireless network interface device (e.g. a wireless modem). Varying and controlling the ESR of the power supply rail, relative to an ESR of a super capacitor coupled to the power supply rail, allows control of the currents drawn from the host power supply and a super capacitor. During a time when the wireless network interface device is transmitting or is about to transmit, the ESR of the power supply rail is increased so that it exceeds the ESR of the super capacitor, thereby causing current for the power amplifier (PA) of the wireless network interface device to be drawn primarily from the super capacitor, rather than from the host power supply. During a time when the wireless network interface device has completed transmitting or is about to complete transmitting, the ESR of the host power supply is lowered so that it is less than the ESR of the super capacitor, thereby causing the super capacitor to enter a charging state.
摘要翻译：用于改变和控制被配置为将功率从主机设备的电源传输到无线网络接口设备（例如，无线调制解调器）的电源轨的有效串联电阻（ESR）的方法和装置。改变和控制电源轨的ESR相对于耦合到电源轨的超级电容的ESR允许控制从主电源和超级电容器吸取的电流。在无线网络接口设备正在传输或正在传输的时间内，电源轨的ESR增加，使其超过超级电容器的ESR，从而导致无线电功率放大器（PA）的电流网络接口设备主要从超级电容器中抽取，而不是从主机供电。在无线网络接口设备完成发送或即将完成传输的时间内，主电源的ESR降低，使其小于超级电容器的ESR，从而使超级电容器进入充电状态州。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式