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1. 发明申请

WO2011041684A3 ENDOTRACHEAL TUBE APPARATUS 审中-公开
公开(公告)号：WO2011041684A3
公开(公告)日：2011-06-23
申请号：PCT/US2010051132
申请日：2010-10-01
申请人： MEDTRONIC XOMED INC , HACKER DAVID , STANISLAUS CHARLES , LI WENJENG , LITTLE DAVE , YAMASAKI SONNY , BRUNNETT WILLIAM , MCFARLIN KEVIN , HISSONG BRITT , VACCARO ROB , MURPHY JOHN , PAGOTTO CARLA , SCHULER TINO
发明人： HACKER DAVID , STANISLAUS CHARLES , LI WENJENG , LITTLE DAVE , YAMASAKI SONNY , BRUNNETT WILLIAM , MCFARLIN KEVIN , HISSONG BRITT , VACCARO ROB , MURPHY JOHN , PAGOTTO CARLA , SCHULER TINO
IPC分类号： A61N1/05 , A61B5/0488
CPC分类号： A61B5/6853 , A61B1/00082 , A61B1/00147 , A61B1/005 , A61B1/015 , A61B1/018 , A61B1/04 , A61B1/07 , A61B1/267 , A61B1/2673 , A61B5/01 , A61B5/04012 , A61B5/0421 , A61B5/0488 , A61B5/04886 , A61B5/0492 , A61B5/062 , A61B5/064 , A61B5/065 , A61B5/07 , A61B5/11 , A61B2562/0209 , A61B2562/0215 , A61B2562/0219 , A61B2562/0261 , A61B2562/046 , A61M16/04 , A61M16/0411 , A61M16/0434 , A61M16/0443 , A61M16/0445 , A61M16/0459 , A61M16/0463 , A61M16/0488 , A61M16/0825 , A61M2205/0233 , A61M2205/0294 , A61M2205/3306 , A61M2205/332 , A61M2205/3344 , A61M2205/3368 , A61M2205/3546 , A61M2205/3569 , A61M2205/3592 , A61M2205/6054 , A61M2210/065 , A61M2230/08 , A61N1/0517 , A61N1/0519
摘要： An apparatus for monitoring EMG signals of a patient's laryngeal muscles includes an endotracheal tube having an exterior surface. Conductive ink electrodes are formed on the exterior surface of the endotracheal tube. The conductive ink electrodes are configured to receive the EMG signals from the laryngeal muscles when the endotracheal tube is placed in a trachea of the patient. At least one conductor is coupled to the conductive ink electrodes and is configured to carry the EMG signals received by the conductive ink electrodes to a processing apparatus.
摘要翻译：用于监测患者喉部肌肉的EMG信号的装置包括具有外表面的气管内导管。导管墨水电极形成在气管导管的外表面上。当气管导管放置在患者的气管中时，导电墨水电极被配置为接收来自喉部肌肉的EMG信号。至少一个导体耦合到导电墨水电极并且被配置为将由导电墨水电极接收的EMG信号运送到处理设备。

2. 发明申请

WO2006105157A2 MOUNT FOR DIGITALLY ENHANCED NIGHT VISION DEVICE 审中-公开
标题翻译：数字增强夜视设备的安装
公开(公告)号：WO2006105157A2
公开(公告)日：2006-10-05
申请号：PCT/US2006011403
申请日：2006-03-29
申请人： LITTON SYSTEMS INC , BOURREE LOIG , MURPHY JOHN , PRUET JAMES , MCMAHAN WILLIAM
发明人： BOURREE LOIG , MURPHY JOHN , PRUET JAMES , MCMAHAN WILLIAM
IPC分类号： A61B5/04
CPC分类号： F41H1/04 , F41G1/32 , G02B7/002 , G02B23/125 , G02B27/0176 , G02B2027/0138 , G02B2027/0156
摘要： A system (M) for removably mounting a device (D) that is viewable by a user (U) to an essentially rigid headgear (H) includes a removable strap assembly (10) extending about the headgear (H). The strap assembly (10) includes a strap (18) with a first end (20) having a first securing means (24) to engage a first edge (26) of the head gear (H.) A second securing means (28) secures the strap (18) to a second edge (20). A mounting assembly (32) extends from the strap assembly (10) in proximity to a first end (14) of the strap assembly (10) for controllably positioning the device (D) in an ocular axis (34) of the user (U). The mounting assembly (32) controllably adjusts the device (D) along a forward and backward axis (A1), a vertical axis (A4), and a horizontal axis (A2) of the viewer (U).
摘要翻译：用于可拆卸地安装由用户（U）可观看到基本上刚性的头饰（H）的装置（D）的系统（M）包括围绕头饰（H）延伸的可拆卸带组件（10）。带组件（10）包括具有第一端（20）的带子（18），第一端部（20）具有与头部齿轮（H）的第一边缘（26）接合的第一固定装置（24）。第二固定装置（28）将带子（18）固定到第二边缘（20）。安装组件（32）从绑带组件（10）延伸到带组件（10）的第一端（14）附近，用于可控地将设备（D）定位在用户的眼轴（34）（U ）。安装组件（32）沿着前后轴（A1），垂直轴（A4）和观察者（U）的水平轴线（A2）可控制地调节装置（D）。

3. 发明申请

WO2012135671A2 MONOCLONAL ANTIBODIES AGAINST TISSUE FACTOR PATHWAY INHIBITOR (TFPI) 审中-公开
标题翻译：单克隆抗体对组织因子途径抑制剂（TFPI）
公开(公告)号：WO2012135671A2
公开(公告)日：2012-10-04
申请号：PCT/US2012031538
申请日：2012-03-30
申请人： BAYER HEALTHCARE LLC , WANG ZHUOZHI , MURPHY JOHN , MARQUARDT TOBIAS , MOOSMAYER DIETER
发明人： WANG ZHUOZHI , MURPHY JOHN , MARQUARDT TOBIAS , MOOSMAYER DIETER
IPC分类号： A61K39/395
CPC分类号： C07K16/38 , C07K2317/21 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/622 , C07K2317/92
摘要： Isolated monoclonal antibodies that bind to specific epitopes of human tissue factor pathway inhibitor (TFPI) and the isolated nucleic acid molecules encoding them are provided. Pharmaceutical compositions comprising the anti-TFPI monoclonal antibodies and methods of treating deficiencies or defects in coagulation by administration of the antibodies are also provided.
摘要翻译：提供了与人组织因子途径抑制剂（TFPI）的特异性表位结合的分离的单克隆抗体和编码它们的分离的核酸分子。还提供了包含抗TFPI单克隆抗体的药物组合物和通过施用抗体治疗凝血缺陷或缺陷的方法。

4. 发明申请

WO2006007305A2 METHODS AND DEVICES FOR DIRECTIONALLY ABLATING TISSUE 审中-公开
标题翻译：用于方向抽搐组织的方法和装置
公开(公告)号：WO2006007305A2
公开(公告)日：2006-01-19
申请号：PCT/US2005019962
申请日：2005-06-06
申请人： EDWARDS LIFESCIENCES CORP , WARD JIM , NIEMAN TIM , MURPHY JOHN , DANG NINH HUU , PRUITT TAZI , BULMAN ERIK
发明人： WARD JIM , NIEMAN TIM , MURPHY JOHN , DANG NINH HUU , PRUITT TAZI , BULMAN ERIK
IPC分类号： A61B17/00 , A61B18/00 , A61B18/14 , A61B18/20 , A61B18/22 , A61B18/24 , A61N5/06 , A61N5/067
CPC分类号： A61B18/14 , A61B18/22 , A61B2017/00243 , A61B2018/00196 , A61B2018/2261 , A61B2018/2272
摘要： Ablation instruments and methods are disclosed for ablating diseased tissue such as cardiac tissue. The method includes introducing a flexible elongate member into a predetermined tissue site with a flexible elongate member having a proximal end, a distal end and a longitudinal lumen extending therebetween. A slidable conductor is positioned through the lumen proximate to the tissue site and energy is transmitted to the distal end of the elongate member through the conductor. The flexible elongate member is both longitudinally flexible and resists twisting during bending. The target tissue is ablated, coagulated or photochemically modulated without damaging surrounding tissue.
摘要翻译：公开消融器具和方法来消融诸如心脏组织的病变组织。该方法包括将柔性细长构件引入预定的组织部位，其中柔性细长构件具有近端，远端和在其间延伸的纵向内腔。可滑动的导体通过内腔定位成靠近组织部位，并且能量通过导体传递到细长构件的远端。柔性细长构件纵向柔性并且在弯曲期间抵抗扭转。目标组织被消融，凝固或光化学调节而不损伤周围的组织。

5. 发明申请

WO2007003939A3 A METHOD OF AND A SYSTEM FOR AUTHENTICATION 审中-公开
标题翻译：一种鉴别系统和方法
公开(公告)号：WO2007003939A3
公开(公告)日：2007-05-31
申请号：PCT/GB2006002476
申请日：2006-07-04
申请人： KNOWLES CHRISTOPHER , MURPHY JOHN , O'CONNOR BRIAN , BUTTERS EDWARD JOHN
发明人： KNOWLES CHRISTOPHER , MURPHY JOHN , O'CONNOR BRIAN , BUTTERS EDWARD JOHN
IPC分类号： G06Q20/00 , G07F7/10
CPC分类号： G06Q20/40 , G06Q20/32 , G06Q20/341 , G07F7/0886 , G07F7/1008 , G07F7/1025
摘要： A system for authentication comprises a number of user authentication devices, a central processor and a number of user authentication device readers coupled to the central processor. Each user authentication device has a first data set stored thereon and the central processor has a number of second data sets stored thereon. Each first data set stored on a user authentication device corresponds to a second data set stored on the central computer, and, when a user authentication device is read by an authentication device reader, a portion of the first data set is selected and compared with a second data set. The computer authenticates the user authentication device if the portion of the first data set matches a portion of the second data set corresponding to the read user authentication device. There is also disclosed a method of authentication.
摘要翻译：用于认证的系统包括多个用户认证装置，中央处理器和耦合到中央处理器的多个用户认证装置读取器。每个用户认证装置具有存储在其上的第一数据集，并且中央处理器具有存储在其上的多个第二数据集。存储在用户认证装置上的每个第一数据组对应于存储在中央计算机上的第二数据组，并且当认证装置读取器读取用户认证装置时，选择第一数据组的一部分并与第二个数据集。如果第一数据集的该部分与对应于读取的用户认证装置的第二数据集的一部分匹配，则计算机认证用户认证装置。还公开了一种认证方法。

6. 发明申请

WO2006034134A2 ANTIBACTERIAL PEPTIDE WITH ACTIVITY AGAINST B. ANTHRACIS 审中-公开
标题翻译：具有活性的抗生素肽B.抗生素
公开(公告)号：WO2006034134A2
公开(公告)日：2006-03-30
申请号：PCT/US2005033376
申请日：2005-09-20
申请人： BOSTON MEDICAL CT CORP , MURPHY JOHN , HARRISON ROBERT J
发明人： MURPHY JOHN , HARRISON ROBERT J
IPC分类号： C07K7/08 , A61K38/10 , A61P31/04
CPC分类号： C07K7/08
摘要： Disclosed is a therapeutic peptide useful in the treatment or prevention of infection caused by Gram-positive bacteria such as Bacillus anthracis.
摘要翻译：公开了用于治疗或预防由革兰氏阳性菌如炭疽芽孢杆菌引起的感染的治疗肽。

7. 发明申请

WO2009158511A8 FACTOR VIII MUTEINS WITH REDUCED IMMUNOGENICITY 审中-公开
标题翻译：具有降低免疫原性的因子VIII
公开(公告)号：WO2009158511A8
公开(公告)日：2011-01-13
申请号：PCT/US2009048680
申请日：2009-06-25
申请人： BAYER HEALTHCARE LLC , ASWAD FRED JULLIEN , HARKINS RICHARD , LIU HSIAO-LAI , MURPHY JOHN , WU FAYE , ZHU YING
发明人： ASWAD FRED JULLIEN , HARKINS RICHARD , LIU HSIAO-LAI , MURPHY JOHN , WU FAYE , ZHU YING
IPC分类号： C12P21/06
CPC分类号： C07K14/755 , A61K38/00
摘要： The invention relates to modified Factor VIII molecules with reduced N-linked glycosylation and reduced immunogenicity. The invention also relates to methods of using modified Factor VIII molecules, for example, to treat patients afflicted with hemophilia.
摘要翻译：本发明涉及具有降低的N-连接糖基化和降低的免疫原性的修饰的因子VIII分子。本发明还涉及使用修饰的因子VIII分子的方法，例如治疗患有血友病的患者。

8. 发明申请

WO2007106518A8 SYSTEM FOR AND METHOD FOR PSYCHOLOGICAL ASSESSMENT 审中-公开
标题翻译：心理评估系统和方法
公开(公告)号：WO2007106518A8
公开(公告)日：2009-03-26
申请号：PCT/US2007006398
申请日：2007-03-13
申请人： SPHERICAL DYNAMICS INC , STURM W MICHAEL , WELLS MELISSA MEREDITH , HOLT BRUCE , YOKLEY EDWARD M , MURPHY JOHN
发明人： STURM W MICHAEL , WELLS MELISSA MEREDITH , HOLT BRUCE , YOKLEY EDWARD M , MURPHY JOHN
IPC分类号： A61B5/16
CPC分类号： G09B19/00
摘要： In systems, methods and program products relating to the assessment of individuals, a subject can be provided with an assessment through software and a computer for improved functionality. The software may be directly installed on the subject's computer or may be on a remote server accessible through a communication network, such as a local network or the Internet. Stimuli to be presented to subject are selected in real time and may be selected randomly from a database of stimuli. Further, in the event of borderline cases, a refinement process may be used to provide an accurate assessment of the subject. Methods for the assessment of teams, comprising subject individuals, for the construction of ideal process profiles, and for coaching individuals are provided.
摘要翻译：在与个人评估有关的系统，方法和程序产品中，可以通过软件和计算机提供对主题的评估以改进功能。该软件可以直接安装在被摄体的计算机上，或者可以在可通过诸如本地网络或因特网的通信网络访问的远程服务器上。要呈现给受试者的刺激被实时选择，并且可以从刺激数据库中随机选择。此外，如果发生边界案件，可以使用细化过程来提供对主题的准确评估。提供了评估团队的方法，包括受试者个人，构建理想的过程简档和辅导人员。

9. 发明申请

WO2008051859A3 OPTICAL CATHETER AND PULLBACK AND ROTATION SYSTEM AND METHOD 审中-公开
标题翻译：光导管和拉杆和旋转系统及方法
公开(公告)号：WO2008051859A3
公开(公告)日：2008-08-07
申请号：PCT/US2007081978
申请日：2007-10-19
申请人： INFRAREDX , ABELE CHARLES , STRICKLER PETER , MURPHY JOHN , CAPLAN JAY D
发明人： ABELE CHARLES , STRICKLER PETER , MURPHY JOHN , CAPLAN JAY D
IPC分类号： A61B5/00
CPC分类号： A61B5/6852 , A61B5/0066
摘要： An optical catheter system comprising an intraluminal catheter that provides optical signals to a patient and carries optical signals from the patient, an outer housing, and an inner carriage that moves longitudinally relative to the outer housing and rotates relative to the outer housing during operation when the catheter system is being driven by a pullback and rotation system. The optical catheter system has an interlock system that prevents rotation and longitudinal movement of the inner carriage in the outer housing until attached to the pullback and rotation system. The pullback and rotation system comprises a frame and a catheter system interface, attached to the frame, to which the catheter system is coupled. A carriage drive system is further provided that moves longitudinally and rotates relative to the frame to provide rotation and longitudinal drive to the catheter system.
摘要翻译：一种光学导管系统，其包括管腔内导管，其向患者提供光信号并且携带来自患者的光信号，外壳和内托架，所述光信号在操作期间相对于所述外壳在纵向相对运动时相对于所述外壳旋转，导管系统由拉回和旋转系统驱动。光学导管系统具有互锁系统，其防止内部托架在外部壳体中的旋转和纵向运动，直到附接到回拉和旋转系统。回拉和旋转系统包括附接到框架的框架和导管系统接口，导管系统耦合到框架和导管系统接口。还提供了一种托架驱动系统，该托架驱动系统纵向移动并相对于框架旋转以向导管系统提供旋转和纵向驱动。

10. 发明申请

WO2007106518A2 SYSTEM FOR AND METHOD FOR PSYCHOLOGICAL ASSESSMENT 审中-公开
标题翻译：心理评估系统和方法
公开(公告)号：WO2007106518A2
公开(公告)日：2007-09-20
申请号：PCT/US2007006398
申请日：2007-03-13
申请人： SPHERICAL DYNAMICS INC , STURM W MICHAEL , WELLS MELISSA MEREDITH , HOLT BRUCE , YOKLEY EDWARD M , MURPHY JOHN
发明人： STURM W MICHAEL , WELLS MELISSA MEREDITH , HOLT BRUCE , YOKLEY EDWARD M , MURPHY JOHN
IPC分类号： A61B5/16
CPC分类号： G09B19/00
摘要： In systems, methods and program products relating to the assessment of individuals, a subject can be provided with an assessment through software and a computer for improved functionality. The software may be directly installed on the subject's computer or may be on a remote server accessible through a communication network, such as a local network or the Internet. Stimuli to be presented to subject are selected in real time and may be selected randomly from a database of stimuli. Further, in the event of borderline cases, a refinement process may be used to provide an accurate assessment of the subject. Methods for the assessment of teams, comprising subject individuals, for the construction of ideal process profiles, and for coaching individuals are provided.
摘要翻译：在与个人评估有关的系统，方法和程序产品中，可以通过软件和计算机提供对主题的评估以改进功能。该软件可以直接安装在被摄体的计算机上，或者可以在可通过诸如本地网络或因特网的通信网络访问的远程服务器上。要呈现给受试者的刺激被实时选择，并且可以从刺激数据库中随机选择。此外，如果发生边界案件，可以使用细化过程来提供对主题的准确评估。提供了评估团队的方法，包括受试者个人，构建理想的过程简档和辅导人员。

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