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1. 发明申请

WO2007079375A2 ACTIVE FIXATION CARDIAC VEIN MEDICAL LEAD 审中-公开
标题翻译：主动固定CARDIAC VEIN医用铅
公开(公告)号：WO2007079375A2
公开(公告)日：2007-07-12
申请号：PCT/US2006062609
申请日：2006-12-27
申请人： MEDTRONIC INC , SOMMER JOHN L , HESS DOUGLAS N
发明人： SOMMER JOHN L , HESS DOUGLAS N
IPC分类号： A61N1/00
CPC分类号： A61N1/0573 , A61N2001/0585
摘要： An implantable medical lead configured for active fixation in the vasculature of a patient includes an elongated lead body having a central lumen and a distal tip. Disposed within the central lumen are a fixation helix and an elongated member, such as a lead coil, coupled to the fixation helix. The elongated member is adapted to rotate the fixation helix, thereby causing it to advance or retract within the central lumen of the lead body. The lead body includes a window along a portion of its length through which the fixation helix may be affixed to a blood vessel of the patient's vasculature.
摘要翻译：被配置用于在患者的脉管系统中主动固定的可植入医疗引线包括具有中心腔和远端尖端的细长引线主体。设置在中心腔内的是固定螺旋和连接到固定螺旋的细长构件，诸如导线圈。细长构件适于旋转固定螺旋，从而使其在引线主体的中心腔内前进或后退。导联体包括沿着其长度的一部分的窗口，固定螺旋可通过该窗口固定到患者脉管系统的血管。

2. 发明申请

WO2008036865A3 RADIOFREQUENCY (RF)-SHUNTED SLEEVE HEAD AND USE IN ELECTRICAL STIMULATION LEADS 审中-公开
标题翻译：无线射频（RF）-SHUNTED SLEEVE HEAD AND USE IN ELECTRICAL STIMULATION LEADS
公开(公告)号：WO2008036865A3
公开(公告)日：2008-12-11
申请号：PCT/US2007079112
申请日：2007-09-21
申请人： MEDTRONIC INC , REINKE JAMES D , YANG ZHONGPING , SOMMER JOHN L
发明人： REINKE JAMES D , YANG ZHONGPING , SOMMER JOHN L
IPC分类号： A61N1/37 , A61N1/05 , A61N1/08 , A61N1/16 , A61N1/362
CPC分类号： A61N1/056 , A61N1/086 , A61N1/3718
摘要： A medical device lead is presented. The medical device lead includes a lead body and a tip electrode. A radio frequency shunted sleeve head is coupled to the lead body and to the tip electrode. The sleeve head includes a proximal end and a distal end. A biostable dielectric coating is introduced over the sleeve head.
摘要翻译：提供医疗器械引线。医疗装置引线包括引线体和尖端电极。射频分流套管头与引线主体和尖端电极耦合。套筒头包括近端和远端。在套筒头上引入生物稳定的电介质涂层。

3. 发明申请

WO2006044890A3 SELF-FIXATING IMPLANTABLE SCAFFOLDS FOR THE ADMINISTRATION OF BIOLOGICAL OR PHARMACEUTICAL SUBSTANCES 审中-公开
标题翻译：用于生物或药物物质管理的自固定可植入物
公开(公告)号：WO2006044890A3
公开(公告)日：2006-07-20
申请号：PCT/US2005037430
申请日：2005-10-13
申请人： MEDTRONIC INC , SIGG DANIEL C , HINIDUMA-LOKUGE PRASANGA D , SHARMA VINROD , SOMMER JOHN L
发明人： SIGG DANIEL C , HINIDUMA-LOKUGE PRASANGA D , SHARMA VINROD , SOMMER JOHN L
IPC分类号： A61N1/05 , A61N1/30
CPC分类号： A61L27/50 , A61F2/2493 , A61F2/848 , A61L27/54 , A61L2300/252 , A61L2300/604 , A61M37/0069
摘要： A self-fixating scaffold delivers therapeutic material to tissue for treating various diseases/conditions. A scaffold holds the therapeutic material and is implanted into the tissue. A fixation element anchors the scaffold in the tissue making the scaffold less likely to become dislodged.
摘要翻译：自固定支架将治疗材料递送至组织以治疗各种疾病/病症。支架固定治疗材料并植入组织。固定元件将支架锚定在组织中，使得支架不太可能脱落。

4. 发明申请

WO2006023930A2 NOVEL DISTAL PORTIONS FOR MEDICAL ELECTRICAL LEADS 审中-公开
标题翻译：用于医疗导线的新颖零件
公开(公告)号：WO2006023930A2
公开(公告)日：2006-03-02
申请号：PCT/US2005029989
申请日：2005-08-22
申请人： MEDTRONIC INC , SOMMER JOHN L , BAUER RYAN T , DANG KIEM H
发明人： SOMMER JOHN L , BAUER RYAN T , DANG KIEM H
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0568 , A61N2001/0585
摘要： A medical electrical lead includes a canted lead body distal portion extending from an approximately straight lead body proximal portion and including an approximately straight segment and a hump-like segment extending from a first end, in proximity to the approximately straight segment, to a second end. A first electrode is coupled to the approximately straight segment of the distal portion and a second electrode coupled to the distal portion in proximity to a second end of the hump-like segment. A medical electrode includes an active surface extending from a first end to a second end and has a maximum outer diameter exceeding an outer diameter of the both the first end and the second end. The electrode further includes a recess formed in the active surface and an agent held in the recess and adapted to disperse out from the recess upon implantation of the electrode.
摘要翻译：医用电引线包括倾斜的引线本体远端部分，该倾斜的引线本体远端部分从近似直的引线本体近端部分延伸并且包括近似直线的部分和从近端直线部分附近的第一端延伸到第二端部的隆起状部分。第一电极联接到远侧部分的大致笔直的部分上，以及第二电极联接到远侧部分上接近驼峰状部分的第二端。医用电极包括从第一端延伸到第二端的活性表面，并且具有超过第一端和第二端两者的外径的最大外径。电极还包括形成在活性表面中的凹槽和保持在凹槽中并适于在植入电极时从凹槽分散出去的试剂。

5. 发明申请

WO2009025817A3 EVALUATING THERAPEUTIC STIMULATION ELECTRODE CONFIGURATIONS BASED ON PHYSIOLOGICAL RESPONSES 审中-公开
标题翻译：基于生理反应评估治疗性刺激电极配置
公开(公告)号：WO2009025817A3
公开(公告)日：2009-07-23
申请号：PCT/US2008009906
申请日：2008-08-20
申请人： MEDTRONIC INC , SOMMER JOHN L , BOURN DAVID WAYNE , MARSHALL MARK T , EGGEN MICHAEL D , MIYAZAWA GABRIELA C
发明人： SOMMER JOHN L , BOURN DAVID WAYNE , MARSHALL MARK T , EGGEN MICHAEL D , MIYAZAWA GABRIELA C
IPC分类号： A61N1/362
CPC分类号： A61N1/36514 , A61N1/056 , A61N1/36114 , A61N1/36185 , A61N1/3684 , A61N1/3686 , A61N2001/0585
摘要： A medical system comprises a plurality of electrodes; at least one sensor configured to output at least one signal based on at least one physiological parameter of a patient; and a processor. The processor is configured to control delivery of stimulation to the patient using a plurality of electrode configurations. Each of the electrode configurations comprises at least one of the plurality of electrodes. For each of the electrode configurations, the processor is configured to determine a first response of target tissue to the stimulation based on the signals, and a second response of non-target tissue to the stimulation based on the signals. The processor is also configured to select at least one of the electrode configurations for delivery of stimulation to the patient based on the first and second responses for the electrode configurations. As examples, the target tissue may be a left ventricle or vagus nerve.
摘要翻译：医疗系统包括多个电极; 至少一个传感器，被配置为基于患者的至少一个生理参数输出至少一个信号; 和一个处理器。处理器被配置为使用多个电极配置来控制向患者的刺激的递送。每个电极配置包括多个电极中的至少一个。对于每个电极配置，处理器被配置为基于信号确定目标组织对刺激的第一响应，以及基于信号确定非目标组织对刺激的第二响应。处理器还被配置为基于电极配置的第一和第二响应来选择电极配置中的至少一个以向患者传递刺激。作为例子，目标组织可以是左心室或迷走神经。

6. 发明申请

WO2006105066A3 MEDICAL ELECTRICAL LEAD WITH CO-RADIAL MULTI-CONDUCTOR COIL 审中-公开
标题翻译：医用电线与同轴多导体线圈
公开(公告)号：WO2006105066A3
公开(公告)日：2007-05-31
申请号：PCT/US2006011241
申请日：2006-03-28
申请人： MEDTRONIC INC , BAUER RYAN T , SOMMER JOHN L
发明人： BAUER RYAN T , SOMMER JOHN L
IPC分类号： A61N1/05 , A61N1/37
CPC分类号： A61N1/05 , A61N1/056 , A61N1/086 , A61N1/37 , A61N1/3718 , A61N1/3752
摘要： A multi-conductor medical electrical lead comprises a connector located at a proximal end of the lead, one or more electrodes located at a distal end of the lead and a co-radial multi-conductor coil connecting the connector with the electrode(s), wherein the coil has a lead body region with co-radially wound conductors and has an inductance greater than or equal to approximately 1.5 µH.
摘要翻译：多导体医用电线包括位于引线近端的连接器，位于引线前端的一个或多个电极和连接器与电极的同向径向多导体线圈，其中所述线圈具有引导体区域，所述引线体区域具有共同径向缠绕的导体并具有大于或等于约1.5μH的电感。

7. 发明申请

WO2006023930A9 NOVEL DISTAL PORTIONS FOR MEDICAL ELECTRICAL LEADS 审中-公开
标题翻译：医疗电源领域的新兴领域
公开(公告)号：WO2006023930A9
公开(公告)日：2007-04-26
申请号：PCT/US2005029989
申请日：2005-08-22
申请人： MEDTRONIC INC , SOMMER JOHN L , BAUER RYAN T , DANG KIEM H
发明人： SOMMER JOHN L , BAUER RYAN T , DANG KIEM H
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0568 , A61N2001/0585
摘要： A medical electrical lead includes a canted lead body distal portion extending from an approximately straight lead body proximal portion and including an approximately straight segment and a hump-like segment extending from a first end, in proximity to the approximately straight segment, to a second end. A first electrode is coupled to the approximately straight segment of the distal portion and a second electrode coupled to the distal portion in proximity to a second end of the hump-like segment. A medical electrode includes an active surface extending from a first end to a second end and has a maximum outer diameter exceeding an outer diameter of the both the first end and the second end. The electrode further includes a recess formed in the active surface and an agent held in the recess and adapted to disperse out from the recess upon implantation of the electrode.
摘要翻译：医用电引线包括从大致直的引线主体近端部分延伸的倾斜的引线体远端部分，并且包括大致直的部分和从第一端部延伸到大致直线段的隆起状部分到第二端部。第一电极耦合到远侧部分的大致直线段，以及第二电极，其耦合到靠近驼峰状段的第二端的远侧部分。医疗电极包括从第一端延伸到第二端的有效表面，并且具有超过第一端和第二端的外径的最大外径。所述电极还包括形成在所述活性表面中的凹部和保持在所述凹部中并适于在注入所述电极时从所述凹部分散出的试剂。

8. 发明申请

WO2006060760A3 HIGH IMPEDANCE ACTIVE FIXATION ELECTRODE OF AN ELECTRICAL MEDICAL LEAD 审中-公开
标题翻译：医用电极的高阻抗主动固定电极
公开(公告)号：WO2006060760A3
公开(公告)日：2006-08-17
申请号：PCT/US2005043887
申请日：2005-12-05
申请人： MEDTRONIC INC , COLES JAMES A JR , SOMMER JOHN L , SIGG DANIEL C
发明人： COLES JAMES A JR , SOMMER JOHN L , SIGG DANIEL C
IPC分类号： A61N1/05
CPC分类号： A61N1/0573
摘要： Electrical medical leads having active fixation electrodes, particularly helix electrodes intended to be screwed into body tissue, e.g., the heart, are disclosed having selectively applied insulation to optimize exposed electrode surface area and dispose the exposed electrode surface area toward tissue that is less traumatized by injury caused by screwing in the fixation helix. In a preferred fabrication method, an outer helical surface is masked by contact with a masking tube while a dielectric coating is applied to the inner helical surface of the coil turns of the helix, and the masking tube is removed when the dielectric coating has set. In one variation, at least one aperture is formed through the masking tube sidewall exposing an area of the outer helical surface thereby interrupting the uninsulated outer helical electrode.
摘要翻译：公开了具有主动固定电极的电医疗引线，特别是旨在拧入人体组织（例如心脏）中的螺旋电极，其具有选择性施加的绝缘以优化暴露的电极表面区域并且将暴露的电极表面区域朝向组织拧入固定螺旋引起的损伤。在优选的制造方法中，通过与屏蔽管接触而屏蔽外螺旋表面，同时将介电涂层施加到螺旋的线圈匝的内螺旋表面上，并且当介电涂层凝固时去除掩蔽管。在一个变型中，穿过掩蔽管侧壁形成至少一个孔，从而暴露外部螺旋形表面的区域，从而中断未绝缘的外部螺旋形电极。

9. 发明申请

WO2004060484A3 MEDICAL LEAD CONNECTION SYSTEM 审中-公开
标题翻译：医疗领导连接系统
公开(公告)号：WO2004060484A3
公开(公告)日：2004-11-04
申请号：PCT/US0340250
申请日：2003-12-15
申请人： MEDTRONIC INC
发明人： SOMMER JOHN L , WILLIAMS TERRELL M
IPC分类号： A61N1/05 , A61N1/375 , H01R13/52 , H01R24/58 , H01R31/06
CPC分类号： A61N1/3752 , A61N1/056 , A61N2001/0578 , A61N2001/0585 , H01R13/5224 , H01R24/58 , H01R31/06 , H01R2107/00 , H01R2201/12
摘要： A system for implanting a medical electrical lead includes an elongated lead body and a relatively non-compliant lead extension joined to a proximal end of the proximal portion of the lead body. The lead body includes a plurality of connector rings positioned about a proximal portion of the lead body. The lead extension includes a plurality of temporary contact surfaces and a plurality of conductors wherein each conductor joins a temporary contact surface to a corresponding connector ring.
摘要翻译：用于植入医用电引线的系统包括细长的导线主体和连接到导线主体的近端部分的近端的相对不顺应的引线延伸部。引线主体包括围绕引线主体的近端部分定位的多个连接器环。引线延伸部包括多个临时接触表面和多个导体，其中每个导体将临时接触表面连接到相应的连接器环。

10. 发明申请

WO03090832A9 METHOD AND SYSTEM FOR DELIVERING A MEDICAL ELECTRICAL LEAD WITHIN A VENOUS SYSTEM 审中-公开
标题翻译：用于在通气系统中输送医用电线的方法和系统
公开(公告)号：WO03090832A9
公开(公告)日：2004-04-15
申请号：PCT/US0309725
申请日：2003-03-28
申请人： MEDTRONIC INC
发明人： KELLEY JAMES F , VAUGHAN JAMES H , SPEAR STANTON C , HINE DOUGLAS S , GARDESKI KENNETH C , BJORKLUND VICKI L , MEREGOTTE PEDRO A , SOMMER JOHN L , MAIER JOHN J
IPC分类号： A61N1/372 , A61B18/14 , A61M25/00 , A61M25/01 , A61M25/06 , A61N1/05 , A61N1/06
CPC分类号： A61M25/0138 , A61B18/1492 , A61B2017/22038 , A61M25/005 , A61M25/0054 , A61M25/0141 , A61M25/0147 , A61M25/0668 , A61M25/09 , A61M25/09041 , A61M2025/0042 , A61M2025/0047 , A61M2025/0081 , A61M2025/0161 , A61M2025/0681 , A61M2025/1052 , A61M2025/1079 , A61N1/056 , A61N1/06 , A61N1/372 , A61N2001/0578 , A61N2001/0585
摘要： ABSTRACT A loading device for loading a guide wire within a medical electrical lead that includes a navigation portion, having an outer portion, and extending from a front end to a back end, and having an opening formed at the back end. An engagement cavity receives and properly orientates the lead distal tip to align the lumen of the lead with the opening of the navigation portion during the loading of the guide wire within the lead. A first side wall is spaced from a second side wall to form a slot extending along the outer portion from the front end to the back end of the navigation portion, and the guide wire is advanced through the slot as the lead having the guide wire loaded therein is removed from the loading device.
摘要翻译：摘要：一种用于将导丝装载在医疗用电线内的装载装置，其包括具有外部的导航部，并且从前端延伸到后端，并且在后端形成有开口。接合腔容纳并适当地定向引线远侧末端，以在引导线在引线内的加载期间使引线的内腔与引导部分的开口对准。第一侧壁与第二侧壁间隔开以形成沿着导引部分的前端到后端的外部部分延伸的狭槽，并且当导线加载有引导线时，导丝线通过狭槽前进其中的装载装置被移除。

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