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1. 发明申请

WO2007100396A3 FLUID DELIVERY SYSTEM, FLUID PATH, AND MEDICAL CONNECTOR FOR USE WITH THE FLUID DELIVERY SYSTEM AND FLUID PATH 审中-公开
标题翻译：流体输送系统，流体路径和医疗连接器，用于流体输送系统和流体路径
公开(公告)号：WO2007100396A3
公开(公告)日：2007-12-13
申请号：PCT/US2006061269
申请日：2006-11-28
申请人： MEDRAD INC , TROMBLEY FREDERICK W III , COWAN KEVIN P , MCEWEN KRAIG , HAVRILLA JOSEPH B
发明人： TROMBLEY FREDERICK W III , COWAN KEVIN P , MCEWEN KRAIG , HAVRILLA JOSEPH B
IPC分类号： A61M25/00 , A61M5/00
CPC分类号： A61M39/10 , A61M39/12 , A61M2039/1033 , A61M2039/1038
摘要： A medical connector includes a body defining a lumen for fluid flow through the medical connector. The medical connector includes a luer member and an annular member disposed about the luer member. The annular member includes internal and/or external engagement structures. The medical connector may be provided on the outlet of a syringe or on a catheter. A fluid path is disclosed including a first section and a second section. The first and second sections may each include a medical connector to provide a removable connection with a syringe and a catheter, respectively. The medical connector may provide a removable connection between the first and second sections. A fluid delivery system is disclosed including an injector, a syringe operatively associated with the injector, and a fluid path connecting the syringe and a source of injection. The medical connector may provide a removable connection between the syringe and fluid path.
摘要翻译：医疗连接器包括限定用于通过医疗连接器的流体流动的内腔的主体。医疗连接器包括鲁尔构件和围绕鲁尔构件设置的环形构件。环形构件包括内部和/或外部接合结构。医疗连接器可以设置在注射器的出口或导管上。公开了一种包括第一部分和第二部分的流体路径。第一和第二部分可以各自包括医疗连接器，以分别提供与注射器和导管的可移除连接。医疗连接器可以在第一和第二部分之间提供可移除的连接。公开了一种流体递送系统，其包括注射器，与注射器可操作地相关联的注射器以及连接注射器和注射源的流体路径。医疗连接器可以在注射器和流体路径之间提供可移除的连接。

2. 发明申请

WO02066100A8 SYRINGES, CONNECTORS, AND SYRINGE AND CONNECTOR SYSTEMS FOR USE IN FLUID DELIVERY SYSTEMS 审中-公开
标题翻译：液体输送系统中使用的SYRINGES，连接器和注射器和连接器系统
公开(公告)号：WO02066100A8
公开(公告)日：2004-02-26
申请号：PCT/US0204827
申请日：2002-02-20
申请人： MEDRAD INC
发明人： COWAN KEVIN P , HITCHINS MARK W , BISEGNA JOSEPH E , MCFALL FRANK B , TROMBLEY FREDERICK W III , GRUBIC HERBERT M , REILLY DAVID M , UBER ARTHUR E III , SCIULLI FRANCIS J , SCHRIVER RALPH H
IPC分类号： A61M39/10 , A61M5/14 , A61M25/00
CPC分类号： A61M39/1011 , A61M2039/1033 , A61M2039/1044

3. 发明申请

WO2007053779A3 DELIVERY OF AGENTS TO TISSUE 审中-公开
标题翻译：药剂运送到组织
公开(公告)号：WO2007053779A3
公开(公告)日：2007-11-08
申请号：PCT/US2006043134
申请日：2006-11-06
申请人： MEDRAD INC , UBER ARTHUR E III , TROMBLEY FREDERICK W III , GELBLUM EUGENE A , RHINEHART EDWARD J , REILLY DAVID M , CEDARHOLM PAGE , COWAN KEVIN P , TROCKI MARK , HIRSCHMAN ALAN D
发明人： UBER ARTHUR E III , TROMBLEY FREDERICK W III , GELBLUM EUGENE A , RHINEHART EDWARD J , REILLY DAVID M , CEDARHOLM PAGE , COWAN KEVIN P , TROCKI MARK , HIRSCHMAN ALAN D
IPC分类号： A61M5/30 , A61M31/00
CPC分类号： A61J1/1443 , A61J1/1456 , A61J1/1475 , A61M5/142 , A61M5/1723 , A61M5/3145 , A61M31/005 , B01L3/502 , B01L2300/044 , B01L2300/0681 , G06F19/3468
摘要： A system for injecting an injectate into patient includes a first pressurizable container for holding the injectate; a patient interface in fluid connection with the first pressurizable container, the patient interface being adapted to pass the injectate into tissue of the patient; a powered injector in operative connection with the first pressurizable container to pressurize the injectate; a controller system in operative connection with powered injector; and a stereotactic localization frame adapted to be placed in operative connection with the patient interface to assist in controlling localization of the patient interface. A system for processing cells (and/or other injectate components) includes a container and a plunger adapted to be slidably positioned within the container. The system includes at least one inlet port through which a fluid can enter the system and at least one effluent port through which an effluent can exit the system. The plunger section forms a sealing engagement with the inner wall of the container such that rearward motion of the plunger is adapted to draw fluid into the system via the inlet and forward motion of the plunger is adapted to force effluent out of the system via the effluent port.
摘要翻译：一种用于将注射剂注入患者体内的系统包括用于保持注射剂的第一可加压容器; 与第一可加压容器流体连接的患者接口，患者接口适于将注射液传递到患者的组织; 动力注射器，其与第一可加压容器可操作地连接以对注射物加压; 与动力注射器可操作连接的控制器系统; 以及立体定位框架，适于与患者接口操作连接，以帮助控制患者接口的定位。用于处理细胞（和/或其他注射组分）的系统包括容器和适于可滑动地定位在容器内的柱塞。该系统包括流体可以通过其进入系统的至少一个入口和至少一个流出物可以通过其流出系统的流出口。柱塞部分与容器的内壁形成密封接合，使得柱塞的向后运动适于经由入口将流体吸入系统中，并且柱塞的向前运动适于通过流出物将流出物排出系统港口。

4. 发明申请

WO0180928A3 FLUID DELIVERY SYSTEMS, INJECTOR SYSTEMS AND METHODS OF FLUID DELIVERY 审中-公开
标题翻译：流体输送系统，喷射器系统和流体输送方法
公开(公告)号：WO0180928A3
公开(公告)日：2002-02-21
申请号：PCT/US0112781
申请日：2001-04-19
申请人： SCHERING AG , MEDRAD INC
发明人： URICH KLAUS , EMIG MICHAEL F , TROMBLEY FREDERICK W III , HAVRILLA JOSEPH B , RHINEHART EDWARD J , CALLAN GERALD W
IPC分类号： A61M5/00 , A61M5/14 , A61M5/168 , A61M39/26
CPC分类号： A61M5/1407 , A61M5/007 , A61M5/16827 , A61M39/26 , Y10S128/01
摘要： A fluid delivery system for delivery of an injection fluid to a patient generally includes a pump system to pressurize the injection fluid, a patient interface in removable fluid connection with the pump system, and a connector in fluid connection between the pump system and the patient interface. The pump system is connected to an inlet of the connector, and the patient interface is removably connected to an outlet of the connector. The connector includes a sealing member at least partly disposed within a housing of the connector that is biased to close the outlet when the patient interface is removed.
摘要翻译：用于将注射流体输送到患者的流体递送系统通常包括泵系统以对注射流体加压，与泵系统可移动流体连接的患者接口，以及在泵系统和患者接口之间的流体连接的连接器。泵系统连接到连接器的入口，患者接口可拆卸地连接到连接器的出口。所述连接器包括至少部分地设置在所述连接器的壳体内的密封构件，当所述患者接口被移除时，所述密封构件被偏置以关闭所述出口。

5. 发明申请

WO2008083313A3 METHODS AND SYSTEMS FOR INTEGRATED RADIOPHARMACEUTICAL GENERATION, PREPARATION, TRANSPORTATION, AND ADMINISTRATION 审中-公开
标题翻译：综合放射免疫法生成，制备，运输和管理的方法与系统
公开(公告)号：WO2008083313A3
公开(公告)日：2009-07-23
申请号：PCT/US2007089101
申请日：2007-12-28
申请人： MEDRAD INC , HIRSCHMAN ALAN D , UBER ARTHUR E III , COWAN KEVIN P , REILLY DAVID M , RHINEHART EDWARD J , KALAFUT JOHN F , UBER BRONWYN , TROMBLEY FREDERICK W III , REMIS STEVEN J , LEVIN PAUL , GRIFFITH SCOTT , DESCALZI DOUGLAS , DEWIT RICHARD
发明人： HIRSCHMAN ALAN D , UBER ARTHUR E III , COWAN KEVIN P , REILLY DAVID M , RHINEHART EDWARD J , KALAFUT JOHN F , UBER BRONWYN , TROMBLEY FREDERICK W III , REMIS STEVEN J , LEVIN PAUL , GRIFFITH SCOTT , DESCALZI DOUGLAS , DEWIT RICHARD
IPC分类号： A61M5/172 , A61B6/00 , G21G4/08
CPC分类号： A61N5/1001 , A61B5/0205 , A61B5/055 , A61B5/7289 , A61B6/032 , A61B6/037 , A61B6/0478 , A61B6/107 , A61B6/4057 , A61B6/4258 , A61B6/4423 , A61B6/507 , A61B6/508 , A61B6/5288 , A61B6/548 , A61M5/007 , A61M5/14546 , A61M5/1456 , A61M5/16827 , A61M5/16881 , A61M5/1723 , A61M5/1785 , A61M2205/3576 , A61N5/1071 , A61N2005/1021 , A61N2005/1094 , G06F19/3468 , G21F5/015 , G21G4/08
摘要： An integrated radiopharmaceutical patient treatment system is disclosed including a patient support platform with an associated patient stimulus apparatus, an imager proximate the patient support platform, a radiopharmaceutical fluid delivery system for infusing a radiopharmaceutical fluid into a patient, a patient monitor to be associated with a patient, and an integrated system controller operably associated with the patient stimulus apparatus, imager, radiopharmaceutical fluid delivery system, and patient monitor to control and coordinate their operations. Within the patient treatment system the radiopharmaceutical fluid delivery system may be included comprising a radionuclide supply module, a radiopharmaceutical processing module, a quality control module, a patient injection module, and a controller. A hazardous fluid handling system including a docking station and a hazardous fluid transport device adapted to detachably dock with the docking station is further disclosed.
摘要翻译：公开了一种集成的放射性药物患者治疗系统，其包括具有相关联的患者刺激装置的患者支撑平台，靠近患者支撑平台的成像器，用于将放射性药物流体输入患者的放射性药物流体输送系统，与患者以及与患者刺激装置，成像器，放射性药物流体输送系统和患者监护器可操作地相关联以控制和协调其操作的集成系统控制器。在患者治疗系统内，可以包括放射性药物流体递送系统，包括放射性核素供应模块，放射性药物处理模块，质量控制模块，患者注射模块和控制器。进一步公开了一种危险的流体处理系统，其包括对接站和适于与对接站可拆卸地对接的危险流体输送装置。

6. 发明申请

WO2005110007A3 FLUID DELIVERY SYSTEMS, PRESSURE ISOLATION MECHANISMS, INJECTOR CONTROL MECHANISMS, AND METHODS OF USE THEREOF 审中-公开
标题翻译：流体输送系统，压力隔离机构，喷射器控制机构及其使用方法
公开(公告)号：WO2005110007A3
公开(公告)日：2006-12-07
申请号：PCT/US2004011190
申请日：2004-04-12
申请人： MEDRAD INC
发明人： TROMBLEY FREDERICK W III , SCHMIDT ROBERT M , REILLY DAVID M , HIRSCHMAN ALAN D , GRIFFITHS DAVID M , CALLAN GERALD W , PEDRAZA LUIS A , KWO JENNIE , ZIRPS CHRISTOPHER T , BEAULIEU RODERICK H
IPC分类号： A61M1/00 , A61M5/00 , A61M5/14 , A61M5/145 , A61M5/168 , A61M5/36 , A61M37/00 , A61M39/22 , A61M39/24
CPC分类号： A61M5/007 , A61M5/14546 , A61M5/16827 , A61M5/16881 , A61M5/36 , A61M39/22 , A61M39/223 , A61M39/24 , A61M2005/1403 , A61M2205/3331 , A61M2205/582
摘要： An injector system includes a source of injection fluid, a pump device, a fluid path set disposed between the source of injection fluid and the pump device, and a fluid control device operatively associated with the fluid path set. The fluid control device is adapted to permit purging of air from the fluid path set and to stop flow of the injection fluid to a patient at substantially any pressure or flow rate generated by the pump device for delivering a sharp bolus of the injection fluid to the patient. The fluid control device is preferably part of the fluid path set between the source of injection fluid and the pump device. In another aspect, an injector system includes a powered injector, a pressurizing chamber in operative connection with the powered injector, a fluid path in fluid connection with the pressurizing chamber, and a manual control in fluid connection with the fluid path. The manual control includes at least one actuator for controlling the injector through application of force by an operator. The actuator provides tactile feedback of pressure in the fluid path to the operator via a fluid connection with the fluid path. A pressure isolation mechanism for use in a medical procedure includes a lumen, an isolation port in fluid connection with the lumen, and a valve having a first state and a second state. The first state occurs when the lumen and the isolation port are connected. The second state occurs when the lumen and the isolation port are disconnected. The lumen remains open for flow of fluid therethrough in the first state and in the second state. The valve is normally in the first state and is switchable to the second state when fluid pressure in the lumen reaches a predetermined pressure level. A pressure transducer can be in fluid connection with the isolation port of the pressure isolation mechanism. A fluid delivery system includes a manually operated syringe and a pressure isolation mechanism as described above.
摘要翻译：注射器系统包括注射流体源，泵装置，设置在注射流体源和泵装置之间的流体路径组以及与流体路径组可操作地相关联的流体控制装置。流体控制装置适于允许从流体路径组清洗空气并且以基本上由泵装置产生的任何压力或流速停止注射流体到患者的流动，用于将喷射流体的尖锐推注物输送到患者。流体控制装置优选地是在注射流体源和泵装置之间设置的流体路径的一部分。在另一方面，喷射器系统包括动力注射器，与动力注射器可操作地连接的加压室，与加压室流体连接的流体路径，以及与流体路径流体连接的手动控制。手动控制包括至少一个执行器，用于通过操作者施加力来控制喷射器。致动器通过与流体路径的流体连接提供到操作者的流体路径中的压力的触觉反馈。用于医疗过程的压力隔离机构包括管腔，与内腔流体连接的隔离口以及具有第一状态和第二状态的阀。当管腔和隔离口连接时，发生第一种状态。当管腔和隔离端口断开时，发生第二种状态。在第一状态和第二状态下，内腔保持打开以使流体流过其中。阀通常处于第一状态，并且当内腔中的流体压力达到预定压力水平时可切换到第二状态。压力传感器可以与压力隔离机构的隔离端口流体连接。流体输送系统包括手动操作的注射器和如上所述的压力隔离机构。

7. 发明申请

WO0141835A3 SYRINGES, SYRINGE TUBING AND FLUID TRANSFER SYSTEMS 审中-公开
标题翻译：灌注，灌注管和流体传输系统
公开(公告)号：WO0141835A3
公开(公告)日：2002-01-03
申请号：PCT/US0033009
申请日：2000-12-06
申请人： MEDRAD INC
发明人： COWAN KEVIN P , TROMBLEY FREDERICK W III , TROCKI MARK , REILLY DAVID M
IPC分类号： A61M5/178 , A61M5/14 , A61M5/145 , A61M5/38
CPC分类号： A61M5/14546 , A61M5/385 , A61M2005/1403
摘要： A syringe includes a body and a plunger disposed therein. The body includes a nozzle formed therein and at least one hub member connected thereto or integrally formed thereon for holding an end of a connector tube. The connector tube includes two ends, each end preferably being connected to a respective hub member to retain the connector tube in contact with the syringe. Preferably, the syringe and the connector tube are packaged in a pre-connected condition for ease of use by the customer. Furthermore, flexible inlet tubing for connection to a syringe for filling the syringe with contrast media, for example, is described. The inlet tubing permits filling of the syringe from either a bag or a bottle and may remain attached to the syringe so that it forms at least a part of the connection to the patient. In addition, an apparatus for facilitating the purge of air from a connector tube that will ultimately be connected between a syringe and a patient is described. The apparatus includes a purging tube connected to the distal end of the connector tubing from the syringe. The purging tube includes a venting cap at its distal end. A flow inhibitor is positioned under the venting cap to cooperate with the venting cap by discouraging the discharge of fluid from the distal end of the purging tube while permitting the discharge of air therefrom.
摘要翻译：注射器包括主体和设置在其中的柱塞。主体包括形成在其中的喷嘴和与其连接或一体地形成在其上的至少一个毂构件，用于保持连接器管的端部。连接器管包括两个端部，每个端部优选地连接到相应的毂部件，以将连接器管保持与注射器接触。优选地，注射器和连接管被包装在预连接状态中，以便客户易于使用。此外，描述了用于连接到注射器的柔性入口管，用于例如用造影剂填充注射器。入口管允许从袋或瓶中填充注射器，并且可以保持附接到注射器，使得其形成与患者的连接的至少一部分。此外，描述了一种便于从最终连接在注射器和患者之间的连接管吹扫空气的装置。该装置包括从注射器连接到连接管的远端的清洗管。吹扫管在其远端包括通气盖。流动抑制剂位于排气盖下面，以与通气帽配合，通过阻止从清洗管的远端排出流体，同时允许排出空气。

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