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1. 发明申请

WO2011030343A1 DEVICES, SYSTEMS AND METHODS FOR ADJUSTING FLUID DELIVERY PARAMETERS 审中-公开
标题翻译：用于调节流体输送参数的装置，系统和方法
公开(公告)号：WO2011030343A1
公开(公告)日：2011-03-17
申请号：PCT/IL2010/000744
申请日：2010-09-07
申请人： MEDINGO LTD. , YODFAT, Ofer , SHAPIRA, Gali , GESCHEIT, Iddo M.
发明人： YODFAT, Ofer , SHAPIRA, Gali , GESCHEIT, Iddo M.
IPC分类号： A61K9/00
CPC分类号： A61M5/16877 , A61M5/14244 , A61M5/16804 , A61M5/16831 , A61M5/172 , A61M2205/3569 , G06F19/3468
摘要： Devices, systems and methods for adjusting fluid delivery based on past or historical fluid delivery data and/or personal parameters of a user are disclosed. Devices, and corresponding systems and methods, may comprise a dispensing unit configured to deliver a fluid from a reservoir into the body of a user and a processor having instructions operating thereon to retrieve data relating to one or more time windows from a memory, assess a correction delivery for the one or more time windows based on the data, determine a new CIR value for the one or more time windows if the correction delivery regularly follows a meal bolus and/or determine a new basal delivery profile for the one or more time windows if the correction delivery regularly precedes a meal bolus.
摘要翻译：公开了用于基于过去或历史的流体输送数据和/或用户的个人参数来调节流体输送的装置，系统和方法。设备和相应的系统和方法可以包括分配单元，其被配置为将流体从储存器输送到用户的身体中;以及处理器，其具有在其上操作的指令以从存储器检索与一个或多个时间窗口相关的数据，基于数据对一个或多个时间窗口进行校正传送，如果校正传送定期地跟随膳食推注和/或确定一个或多个时间的新的基础传送配置文件，则确定一个或多个时间窗口的新的CIR值如果校正交付经常在餐前推注，则窗口。

2. 发明申请

WO2010150257A2 A METHOD AND DEVICE FOR IMPROVING GLYCEMIC CONTROL BASED ON RESIDUAL INSULIN 审中-公开
标题翻译：一种用于改善基于残留胰岛素的糖化控制的方法和装置
公开(公告)号：WO2010150257A2
公开(公告)日：2010-12-29
申请号：PCT/IL2010/000501
申请日：2010-06-23
申请人： MEDINGO LTD. , YODFAT, Ofer , GESCHEIT, Iddo M. , SHAPIRA, Gali
发明人： YODFAT, Ofer , GESCHEIT, Iddo M. , SHAPIRA, Gali
IPC分类号： A61B5/1468 , A61K38/28
CPC分类号： A61M5/168 , A61B5/14532 , A61B5/4839 , A61K38/28 , A61M5/1723
摘要： Disclosed are systems, devices, and methods, including a system that includes a processor-based device implementing at least a residual insulin (RI) determination unit configured to determine a residual insulin in the patient's body at a particular time instance based on bolus doses previously delivered to the body of the patient, each bolus dose being associated with at least one dose value and a time representative of the time that dose value was delivered to the patient's body, and based on dose dependent RI time records that each includes at least a dose value and an associated duration value representative of dose-dependent duration of therapeutic effectiveness of the associated at least the dose value. The system also includes a pump to controllably dispense the insulin from a reservoir to the body of the patient based on the residual insulin determined by the RI determination unit.
摘要翻译：公开了系统，设备和方法，包括系统，其包括实施至少残留胰岛素（RI）确定单元的基于处理器的设备，其被配置为基于先前的推注剂量在特定时间段确定患者体内的残留胰岛素递送到患者体内，每次推注剂量与至少一个剂量值和代表剂量值被递送给患者身体的时间的时间相关联，并且基于剂量依赖性RI时间记录，每个包含至少一个剂量值和相关联的持续时间值，其代表相关联的至少剂量值的治疗有效性的剂量依赖性持续时间。该系统还包括泵，用于基于由RI确定单元确定的残留胰岛素将胰岛素从储存器可控地分配给患者的身体。

3. 发明申请

WO2011089600A1 A METHOD AND DEVICE FOR IMPROVING GLYCEMIC CONTROL 审中-公开
标题翻译：一种改善糖化控制的方法和装置
公开(公告)号：WO2011089600A1
公开(公告)日：2011-07-28
申请号：PCT/IL2011/000061
申请日：2011-01-20
申请人： MEDINGO LTD. , YODFAT, Ofer , SHAPIRA, Gali , GESCHEIT, Iddo M.
发明人： YODFAT, Ofer , SHAPIRA, Gali , GESCHEIT, Iddo M.
IPC分类号： A61M31/00
CPC分类号： A61M5/172 , A61B5/14532 , A61B5/4839 , A61M5/1413 , A61M5/14248 , A61M5/1723 , A61M2005/14268 , A61M2205/502 , A61M2205/505 , A61M2205/52 , A61M2230/201 , G06F19/00 , G06F19/3468
摘要： Systems, devices and methods are presented in the subject disclosure for recommending an insulin dose adapted for use with an insulin delivery device. In some embodiments, the method may include receiving blood glucose (BG) data, determining one or more insulin sensitivity (IS) values associated with the BG data, and determining an insulin dose based on the determined one or more IS values. A system for carrying out such a method is also presented.
摘要翻译：本发明公开了系统，装置和方法，以推荐适用于胰岛素递送装置的胰岛素剂量。在一些实施例中，该方法可以包括接收血糖（BG）数据，确定与BG数据相关联的一个或多个胰岛素敏感性（IS）值，以及基于所确定的一个或多个IS值来确定胰岛素剂量。还提出了一种执行这种方法的系统。

4. 发明申请

WO2009138984A2 DEVICE AND METHOD FOR ALLEVIATING POSTPRANDIAL HYPERGLYCEMIA 审中-公开
标题翻译：用于评估临床高血压的装置和方法
公开(公告)号：WO2009138984A2
公开(公告)日：2009-11-19
申请号：PCT/IL2009/000485
申请日：2009-05-14
申请人： MEDINGO LTD. , YODFAT, Ofer , GESCHEIT, Iddo M. , SHAPIRA, Gali
发明人： YODFAT, Ofer , GESCHEIT, Iddo M. , SHAPIRA, Gali
IPC分类号： G06F19/00
CPC分类号： G06F19/3468 , A61M5/14248 , A61M2005/14208 , A61M2005/14268 , G06F19/00 , G16H15/00
摘要： Embodiments of the present disclosure are directed to methods, systems and devices for alleviating postprandial hyperglycemia, as well as to methods and devices for sustained medical infusion of fluids, using, for example, skin securable insulin dispensing systems/devices.
摘要翻译：本公开的实施例涉及用于减轻餐后高血糖症的方法，系统和装置，以及使用例如皮肤可固化胰岛素分配系统/装置的用于持续医学输注流体的方法和装置。

5. 发明申请

WO2009133558A2 A METHOD FOR SELECTING BOLUS DOSES AND BOLUS DELIVERY PATTERNS IN A DRUG DELIVERY DEVICE 审中-公开
标题翻译：用于选择药物递送装置中的胶体剂量和胶体递送模式的方法
公开(公告)号：WO2009133558A2
公开(公告)日：2009-11-05
申请号：PCT/IL2009/000454
申请日：2009-04-28
申请人： MEDINGO LTD. , YODFAT, Ofer , GESCHEIT, Iddo M. , SHAPIRA, Gali
发明人： YODFAT, Ofer , GESCHEIT, Iddo M. , SHAPIRA, Gali
IPC分类号： G06F19/00
CPC分类号： A61M5/14248 , A61M5/1723 , A61M2005/14296 , A61M2205/3569 , A61M2205/3576 , A61M2205/3592 , A61M2205/502 , A61M2205/52 , A61M2230/201 , G06F19/00 , G06F19/3468
摘要： Embodiments of the present disclosure include methods, systems and devices for selecting a bolus configuration and may include one or more of providing a user interface for selection of one or more user interface elements, where each element corresponds to a bolus configuration of a drug, each element is spatially positioned within a multi-dimensional space corresponding to at least three dimensions and the element's position corresponding to each dimension.
摘要翻译：本公开的实施例包括用于选择推注配置的方法，系统和设备，并且可以包括提供用于选择一个或多个用户界面元素的用户界面中的一个或多个，其中每个元素对应于药物的推注配置，每个元素在空间上位于对应于至少三维的多维空间中，并且元素的位置对应于每个维度。

6. 发明申请

WO2009133557A3 METHODS AND APPARATUSES FOR SELECTING A BOLUS DELIVERY PATTERN IN A DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：WO2009133557A3
公开(公告)日：2009-11-05
申请号：PCT/IL2009/000453
申请日：2009-04-28
申请人： MEDINGO LTD. , YODFAT, Ofer , GESCHEIT, Iddo M. , SHAPIRA, Gali
发明人： YODFAT, Ofer , GESCHEIT, Iddo M. , SHAPIRA, Gali
IPC分类号： G06F19/00 , A61M5/142
摘要： Methods, systems and devices for sustained medical infusion of fluids are described. Some implementations describe portable infusion methods, systems and devices for selecting a pattern of fluid delivery. Some implementations describe skin securable insulin dispensing methods, systems and devices for selecting a delivery pattern according to the nutritional characteristics (e.g. glycemic index, GI, fat content, etc.) of caloric intake of the user.

7. 发明申请

WO2008114254A1 USER INTERFACE FOR SELECTING BOLUS DOSES IN A DRUG DELIVERY DEVICE 审中-公开
标题翻译：用于在药物递送装置中选择螺旋剂的用户界面
公开(公告)号：WO2008114254A1
公开(公告)日：2008-09-25
申请号：PCT/IL2008/000380
申请日：2008-03-19
申请人： MEDINGO LTD. , YODFAT, Ofer , SHAPIRA, Gali , GESCHEIT, Iddo M.
发明人： YODFAT, Ofer , SHAPIRA, Gali , GESCHEIT, Iddo M.
IPC分类号： A61M5/172 , G06F19/00 , A61M5/14 , A61M5/142
CPC分类号： A61M5/14248 , A61M5/1413 , A61M5/1723 , A61M2005/14208 , A61M2005/14268 , A61M2205/3569 , A61M2205/3592 , A61M2205/505 , A61M2205/52 , G06F19/00 , G06Q50/22
摘要： An apparatus and system for selecting a bolus dose of a drug in a drug delivery device is disclosed. A bolus dose is selected from a pre-determined schedule of bolus doses, wherein each dose corresponds to a range of a body analyte levels.
摘要翻译：公开了一种用于在药物递送装置中选择药物的推注剂量的装置和系统。推注剂量选自预先确定的推注剂量时间表，其中每个剂量对应于身体分析物水平的范围。

8. 发明申请

WO2009016638A1 DEVICE FOR FACILITATING INFUSION OF THERAPEUTIC FLUIDS AND SENSING OF BODILY ANALYTES 审中-公开
标题翻译：促进治疗性流感和感染分析的手段
公开(公告)号：WO2009016638A1
公开(公告)日：2009-02-05
申请号：PCT/IL2008/001059
申请日：2008-07-31
申请人： MEDINGO LTD. , YODFAT, Ofer , GESCHEIT, Illai , GESCHEIT, Iddo M.
发明人： YODFAT, Ofer , GESCHEIT, Illai , GESCHEIT, Iddo M.
IPC分类号： A61M5/142 , A61M5/172 , A61M5/158 , A61B5/00
CPC分类号： A61M5/14248 , A61B5/14532 , A61B5/6849 , A61M5/158 , A61M5/1723 , A61M5/1782 , A61M5/3287 , A61M2005/1581 , A61M2005/1585 , G06F19/00
摘要： Disclosed is an assembly for use with a portable therapeutic device. The assembly includes a mounting housing securable to skin of a patient, and a cannula subcutaneously insertable through a passageway provided within the housing. The cannula is configured to be inserted subsequent to securing of the housing to the skin of the patient.
摘要翻译：公开了一种用于便携式治疗装置的组件。该组件包括可固定于患者皮肤的安装壳体，以及通过设置在壳体内的通道皮下可插入的套管。套管被构造成在将壳体固定到患者皮肤之后插入。

9. 发明申请

WO2009066287A2 HYPODERMIC OPTICAL MONITORING OF BODILY ANALYTE 审中-公开
标题翻译：体液分析的超光学监测
公开(公告)号：WO2009066287A2
公开(公告)日：2009-05-28
申请号：PCT/IL2008/001520
申请日：2008-11-20
申请人： MEDINGO LTD. , YODFAT, Ofer , GESCHEIT, Iddo M. , GESCHEIT, Illai , KAIDAR, Ruthy
发明人： YODFAT, Ofer , GESCHEIT, Iddo M. , GESCHEIT, Illai , KAIDAR, Ruthy
IPC分类号： A61B5/00 , A61M5/142
CPC分类号： A61B5/1459 , A61B5/14532 , A61B5/6833 , A61M5/14248 , A61M2005/14268 , A61M2005/1726 , A61M2205/3561 , A61M2205/3592
摘要： Disclosed is a skin adherable device for monitoring analytes in interstitial fluid. The device includes an electromagnetic radiation emitting source and a transmitter for transmitting the electromagnetic radiation between the electromagnetic radiation emitting source and the interstitial fluid. The device further includes a detector, operating electronics and a power supply. The device may include a reusable part and a disposable part.
摘要翻译：公开了一种用于监测组织间液中分析物的皮肤可粘附装置。该装置包括电磁辐射发射源和用于在电磁辐射发射源和组织间液体之间传输电磁辐射的发射器。该装置还包括检测器，操作电子装置和电源。该设备可能包括可重复使用的零件和一次性零件。

10. 发明申请

WO2009016636A2 PORTABLE INFUSION DEVICE PROVIDED WITH MEANS FOR MONITORING AND CONTROLLING FLUID DELIVERY 审中-公开
标题翻译：便携式输液装置，用于监测和控制流体输送
公开(公告)号：WO2009016636A2
公开(公告)日：2009-02-05
申请号：PCT/IL2008/001057
申请日：2008-07-31
申请人： MEDINGO LTD. , YODFAT, Ofer , GESCHEIT, Iddo M.
发明人： YODFAT, Ofer , GESCHEIT, Iddo M.
IPC分类号： A61M5/142
CPC分类号： A61M5/14248 , A61M5/1413 , A61M5/14232 , A61M5/1456 , A61M5/14566 , A61M2005/14252 , A61M2005/14268 , A61M2209/01 , A61M2230/201
摘要： A device and a method for delivering a therapeutic fluid (e.g. insulin) into a body of a patient are provided. In one aspect, the device can be implemented with a help of a patch unit securable to a cradle unit or to the body of the patient. The patch unit can employ a driving mechanism, a power source, a processor, a user interface and a display. The processor can be adapted for controlling the driving mechanism by using one or more inputs. The inputs can corresponding to a basal rate and/or a bolus profile. The display can be adapted for displaying the inputs. The user interface can be adapted for adjusting the inputs.
摘要翻译：提供了一种用于将治疗流体（例如胰岛素）输送到患者体内的装置和方法。在一个方面，可以借助于可固定到支架单元或患者身体的贴片单元来实现该装置。贴片单元可以采用驱动机构，电源，处理器，用户界面和显示器。处理器可以适于通过使用一个或多个输入来控制驱动机构。输入可以对应于基本速率和/或推注轮廓。显示器可以适于显示输入。用户界面可以适应于调整输入。

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