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1. 发明申请

WO2008089483A3 OBLIQUE CENTERLINE FOLLOWING DISPLAY OF CT COLONOGRAPHY IMAGES 审中-公开
公开(公告)号：WO2008089483A3
公开(公告)日：2008-07-24
申请号：PCT/US2008/051676
申请日：2008-01-22
申请人： MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH , JOHNSON, C. Daniel , CARSTON, Michael J. , WENTZ, Robert J. , MANDUCA, Armando
发明人： JOHNSON, C. Daniel , CARSTON, Michael J. , WENTZ, Robert J. , MANDUCA, Armando
IPC分类号： G06K9/00
摘要： A method for displaying colonography images includes presenting a series of oblique images of the colon at sequential locations along the colon centerline. Each image is generally centered on the centerline, presents a field of view generally perpendicular to the centerline, and is oriented with the bottom of the colon down.

2. 发明申请

WO2008089490A2 AXIAL CENTERLINE FOLLOWING DISPLAY OF CT COLONOGRAPHY IMAGES 审中-公开
标题翻译：以下关于CT组合图像显示的轴向中心
公开(公告)号：WO2008089490A2
公开(公告)日：2008-07-24
申请号：PCT/US2008/051703
申请日：2008-01-22
申请人： MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH , JOHNSON, C. Daniel , CARSTON, Michael J. , MANDUCA, Armando , WENTZ, Robert J.
发明人： JOHNSON, C. Daniel , CARSTON, Michael J. , MANDUCA, Armando , WENTZ, Robert J.
IPC分类号： G06T7/20
CPC分类号： G06T19/00 , G06T2210/41 , G06T2219/008
摘要： A method for displaying colonography images includes presenting a series of axial images of the colon at sequential locations along the colon centerline. Each image is generally centered on the centerline and presents a field of view parallel to the axial plane.
摘要翻译：用于显示结肠图像的方法包括在结肠中心线的顺序位置呈现一系列结肠的轴向图像。每个图像通常以中心线为中心，并呈现平行于轴向平面的视场。

3. 发明申请

WO2007030132A2 ELECTRONIC STOOL SUBTRACTION IN CT COLONOGRAPHY 审中-公开
标题翻译：电子粪便在CT造影中的减少
公开(公告)号：WO2007030132A2
公开(公告)日：2007-03-15
申请号：PCT/US2006/005087
申请日：2006-02-14
申请人： MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH , MANDUCA, Armando , CARSTON, Michael, J. , WENTZ, Robert, J. , JOHNSON, C., Daniel
发明人： MANDUCA, Armando , CARSTON, Michael, J. , WENTZ, Robert, J. , JOHNSON, C., Daniel
IPC分类号： G06T7/20
CPC分类号： G06T5/005 , G06T5/30 , G06T7/11 , G06T7/155 , G06T7/174 , G06T2207/10081 , G06T2207/20224 , G06T2207/30028
摘要： A method for processing CT colonography input image voxel data representative of 3-dimensional images of a colon having gas and stool tagged with stool tagging agent, to remove the stool from the images. The input image voxel data is generated by an imaging instrument having a characteristic point spread function representative of instrument blurring. The point spread function of the instrument can be empirically determined, and the image data processed as a function of the point spread function to accurately identify and remove the tagged stool. In one embodiment of the invention, portions of the image data representative of the tagged stool and colon tissue are dilated as a function of the point spread function. In another embodiment, portions of the image data representative of the tagged stool are convolved with the point spread function to determine the fractional amount of stool present in the image portions, and the tagged stool subtracted by reducing the intensities of the associated portions of the image by an amount proportional to the fractional amount of stool present.
摘要翻译：用于处理代表具有用粪便标记剂标记的气体和粪便的结肠的三维图像的CT结肠成像输入图像体素数据以从图像中去除粪便的方法。输入图像体素数据由具有代表仪器模糊的特征点扩展函数的成像仪器生成。仪器的点扩散功能可以凭经验确定，图像数据作为点扩散函数的函数进行处理，以精确识别和移除标记的凳子。在本发明的一个实施例中，表示标记的粪便和结肠组织的图像数据的部分根据点扩散函数而扩张。在另一个实施例中，代表标记粪便的图像数据的部分与点扩散函数卷积以确定图像部分中存在的粪便的分数量，并且通过减少图像的相关部分的强度减去标记的粪便数量与粪便的分数量成正比。

4. 发明申请

WO2008089492A2 ELECTRONIC STOOL SUBTRACTION USING QUADRATIC REGRESSION AND INTELLIGENT MORPHOLOGY 审中-公开
标题翻译：使用四次回归和智能形态学的电子沉降
公开(公告)号：WO2008089492A2
公开(公告)日：2008-07-24
申请号：PCT/US2008/051710
申请日：2008-01-22
申请人： MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH , JOHNSON, C. Daniel , CARSTON, Michael J. , MANDUCA, Armando
发明人： JOHNSON, C. Daniel , CARSTON, Michael J. , MANDUCA, Armando
IPC分类号： A61B5/05
CPC分类号： G06T7/0012 , G06T5/50 , G06T7/12 , G06T2207/10081 , G06T2207/30028
摘要： An improved method for processing image voxel data representative of 3-dimensional images of a colon to remove the effects of tagged stool. The method uses parabolic curve intensity-gradient models representative of the intensity and gradient relationship at a transition between two material types as a function of the fraction of the two materials for each of a plurality of two-material type classes, including a gas-tissue transition model, a gas-stool transition model and a stool-tissue transition model. The voxels are classified into one of a plurality of substance classes including tagged stool, gas, tissue and unknown classes. The unknown class voxels are processed as a function of the intensity-gradient models to classify the unknown class voxels into one of the two-material type classes. The two-material type class voxels are processed as a function of the associated intensity-gradient model to determine the fractions of materials in each voxel. The intensity of the two-material type class voxels is then adjusted as a function of the fraction of the materials in the voxels.
摘要翻译：用于处理表示结肠的3维图像的图像体素数据以改善标记的粪便的效果的改进方法。该方法使用代表两种材料类型之间的过渡处的强度和梯度关系的抛物线曲线强度 - 梯度模型作为两种材料对于多种双材料类型中的每一种的分数的函数，包括气体组织过渡模型，粪便过渡模型和大便组织转移模型。体素分为多种物质类别之一，包括标记的粪便，气体，组织和未知类别。未知类体素作为强度梯度模型的函数进行处理，将未知类体素分类为双材料类型之一。作为相关强度 - 梯度模型的函数处理双材料类型体素，以确定每个体素中材料的分数。然后调整双材料类型体素的强度作为体素中材料分数的函数。

5. 发明申请

WO2008089489A2 SIMULTANEOUS DUAL WINDOW/LEVEL SETTINGS FOR DISPLAY OF CT COLONOGRAPHY IMAGES 审中-公开
标题翻译：用于显示CT组合图像的同时双窗口/等级设置
公开(公告)号：WO2008089489A2
公开(公告)日：2008-07-24
申请号：PCT/US2008/051699
申请日：2008-01-22
申请人： MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH , JOHNSON, C. Daniel , CARSTON, Michael J. , MANDUCA, Armando
发明人： JOHNSON, C. Daniel , CARSTON, Michael J. , MANDUCA, Armando
IPC分类号： G06T7/20
CPC分类号： G06T19/00 , G06T2210/41
摘要： A method for processing and displaying colonography image data. First distance tissue pixels representative of tissue within a first distance of gas pixels representative of gas are processed with a first window/level setting to generate a first setting set of image pixels. Second distance tissue pixels representative of tissue within a second distance of the gas pixels are processed with a second window/level setting to generate a second setting set of image pixels. The second distance is a distance greater than the first distance. A colonography image including both the first and second setting sets of image pixels is then displayed.
摘要翻译：一种处理和显示结肠图像数据的方法。代表气体的气体像素的第一距离内的组织的第一距离组织像素用第一窗口/等级设置进行处理，以生成图像像素的第一设置集合。代表气体像素的第二距离内的组织的第二距离组织像素用第二窗口/等级设置进行处理，以产生图像像素的第二设置集合。第二距离是大于第一距离的距离。然后显示包括图像像素的第一和第二设置组的结构图像。

6. 发明申请

WO2012116364A1 ULTRASOUND VIBROMETRY WITH UNFOCUSED ULTRASOUND 审中-公开
标题翻译：超声波超声波超声波检测
公开(公告)号：WO2012116364A1
公开(公告)日：2012-08-30
申请号：PCT/US2012/026769
申请日：2012-02-27
申请人： MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH , GREENLEAF, James, F. , CHEN, Shigao , MANDUCA, Armando , SONG, Pengfei
发明人： GREENLEAF, James, F. , CHEN, Shigao , MANDUCA, Armando , SONG, Pengfei
IPC分类号： G01N9/24 , G01N21/00 , G01N29/00 , G01N29/04
CPC分类号： A61B8/485 , A61B5/0059 , A61B8/461 , A61B8/5223 , G01N21/17 , G01N29/075 , G01N29/221 , G01N29/2456 , G01N2291/02475 , G01N2291/02827 , G01N2291/0422 , G01R33/4814 , G01S7/52042 , G01S15/8927
摘要： Methods for measuring mechanical properties of an object or subject under examination with an ultrasound system and using unfocused ultrasound energy are provided. Shear waves that propagate in the object or subject are produced by applying unfocused ultrasound energy to the object or subject, and measurement data is acquired by applying focused or unfocused ultrasound energy to at least one location in the object or subject at which shear waves are present Mechanical properties are then calculated from the acquired measurement data.
摘要翻译：提供了使用超声系统测量被检查物体或受试者的机械性能并使用未聚焦的超声能量的方法。通过对物体或被摄体施加未聚焦的超声能量来产生在物体或被摄体中传播的剪切波，并且通过将聚焦或未聚焦的超声能量应用于存在剪切波的物体或对象中的至少一个位置来获取测量数据然后从获取的测量数据计算机械性能。

7. 发明申请

WO2010096701A1 PROJECTION-SPACE DENOISING WITH BILATERAL FILTERING IN COMPUTED TOMOGRAPHY 审中-公开
标题翻译：在计算机图像中的双边滤波投影空间
公开(公告)号：WO2010096701A1
公开(公告)日：2010-08-26
申请号：PCT/US2010/024800
申请日：2010-02-19
申请人： MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH , YU, Lifeng , MANDUCA, Armando , TRZASKO, Joshua , FLETCHER, Joel, G.
发明人： YU, Lifeng , MANDUCA, Armando , TRZASKO, Joshua , FLETCHER, Joel, G.
IPC分类号： G01N23/04 , G06K9/20
CPC分类号： G06T11/005 , G06T2207/20028
摘要： Projection data acquired with an x-ray CT system is filtered using a bilateral filter to reduce image noise and enable the acquisition at lower x-ray dose without the loss of image diagnostic quality. The bilateral filtering is performed before image reconstruction by producing a noise equivalent data set from the acquired projection data and then converting the bilateral filtered values back to a projection data set suitable for image reconstruction.
摘要翻译：用x射线CT系统获取的投影数据使用双边滤波器进行滤波，以降低图像噪声，并能够在较低X射线剂量下进行采集，而不会损失图像诊断质量。通过从获取的投影数据产生噪声等效数据集，然后将双边滤波值转换回适合于图像重建的投影数据集，在图像重构之前执行双边滤波。

8. 发明申请

WO2013067546A1 METHOD FOR CALIBRATION-FREE LOCALLY LOW-RANK ENCOURAGING RECONSTRUCTION OF MAGNETIC RESONANCE IMAGES 审中-公开
标题翻译：用于无校准的低分辨率磁化重建图像的方法
公开(公告)号：WO2013067546A1
公开(公告)日：2013-05-10
申请号：PCT/US2012/063706
申请日：2012-11-06
申请人： MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH , TRZASKO, Joshua, D. , MANDUCA, Armando
发明人： TRZASKO, Joshua, D. , MANDUCA, Armando
IPC分类号： G01V3/00
CPC分类号： G01R33/5611
摘要： A method for reconstructing an image of a subject from multi-coil data acquired with an array of radio frequency ("RF") receiver coils that form a part of a magnetic resonance imaging ("MRI") system without the need for coil sensitivity calibration is provided. A coil data set is acquired for each of the RF receiver coils, for example, by undersampling k-space. A set of image blocks that defines the location and size of each of a plurality of image blocks in the image domain is then selected. The acquired coil data sets and selected image block set are then used to jointly estimate a coil image for each of the plurality of RF receiver coils while promoting locally-low rank structure in the coil images. These coil images are then combined to produce the target image of the subject.
摘要翻译：一种用于利用形成磁共振成像（“MRI”）系统的一部分的射频（“RF”）接收器阵列阵列获取的多线圈数据来重建被摄体的图像的方法，而不需要线圈灵敏度校准被提供。对于每个RF接收器线圈获取线圈数据集，例如通过对k空间进行欠采样。然后选择定义图像域中的多个图像块中的每一个的位置和大小的一组图像块。然后，采集的线圈数据集和所选择的图像块集合共同估计多个RF接收器线圈中的每一个的线圈图像，同时促进线圈图像中的局部低秩结构。然后将这些线圈图像组合以产生被摄体的目标图像。

9. 发明申请

WO2009124263A1 METHOD FOR MAGNETIC RESONANCE ELASTOGRAPHY INVERSION USING A FINITE MEDIUM MODEL 审中-公开
标题翻译：使用有限介质模型进行磁共振ELASTOGRAPHY反演的方法
公开(公告)号：WO2009124263A1
公开(公告)日：2009-10-08
申请号：PCT/US2009/039493
申请日：2009-04-03
申请人： MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH , KOLIPAKA, Arunark , MANDUCA, Armando , MCGEE, Kiaran, P. , EHMAN, Richard, L. , GLASER, Kevin, J.
发明人： KOLIPAKA, Arunark , MANDUCA, Armando , MCGEE, Kiaran, P. , EHMAN, Richard, L. , GLASER, Kevin, J.
IPC分类号： G01R33/563 , A61B8/08
CPC分类号： G01R33/56358 , A61B5/0051 , A61B5/416
摘要： A method for magnetic resonance elastography ("MRE") is described, in which an MRE inversion that accounts for waves propagating in a finite, bounded media is employed. A vibratory motion is induced in a subject and MRE is performed to measure one or more components of the resulting displacement produced in the subject. This displacement data is subsequently filtered to provide a more accurate and computationally efficient method of inversion. Wave equations based on the geometry of the bounded media are then utilized to calculate the material properties of the subject. Such a method allows for the performance of MRE on tissues such as the heart, eye, bladder, and prostate with more accurate results.
摘要翻译：描述了一种用于磁共振弹性成像（“MRE”）的方法，其中采用考虑在有限的有界介质中传播的波的MRE反演。在受试者中诱发振动，并执行MRE以测量在受试者中产生的所得到的位移的一个或多个成分。随后对该位移数据进行滤波以提供更精确和计算上有效的反演方法。然后利用基于有界介质的几何形状的波动方程来计算受试者的材料性质。这种方法允许在更精确的结果上在诸如心脏，眼睛，膀胱和前列腺的组织上表现MRE。

10. 发明申请

WO2015065781A2 SYSTEM AND METHOD FOR MODEL-BASED RECONSTRUCTION OF QUANTITATIVE IMAGES 审中-公开
标题翻译：基于模型的量化图像重建系统与方法
公开(公告)号：WO2015065781A2
公开(公告)日：2015-05-07
申请号：PCT/US2014/061688
申请日：2014-10-22
申请人： MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH , TRZASKO, Joshua, D. , MANDUCA, Armando
发明人： TRZASKO, Joshua, D. , MANDUCA, Armando
IPC分类号： G06F19/00
CPC分类号： G06T11/003 , A61B5/743 , G01R33/5608 , G06T7/0012 , G06T7/0016 , G06T2207/10076 , G06T2207/10088 , G06T2207/10092
摘要： A system and method for estimating a physiological parameter from data acquired with a medical imaging system includes acquiring data with the medical imaging system. A physiological parameter is estimated from the acquired data using an iterative estimation in which a model of the medical imaging system is decoupled from a physics-based model of the acquired data.
摘要翻译：从用医学成像系统获取的数据估计生理参数的系统和方法包括用医学成像系统获取数据。使用迭代估计从所获取的数据估计生理参数，其中医学成像系统的模型与所获取的数据的基于物理的模型解耦。

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