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1. 发明申请

WO2010098929A1 DRUG DELIVERY MANAGEMENT SYSTEMS AND METHODS 审中-公开
标题翻译：药物递送管理系统和方法
公开(公告)号：WO2010098929A1
公开(公告)日：2010-09-02
申请号：PCT/US2010/022242
申请日：2010-01-27
申请人： LIFESCAN, INC. , KRULEVITCH, Peter , WILK, Robert , KRAFT, Ulrich , SAVAGE, Donna , FOLEY, Nick , GLENCROSS, James , SHEPHERD, David , SIEH, Zara , PRICE, David, M., D.
发明人： KRULEVITCH, Peter , WILK, Robert , KRAFT, Ulrich , SAVAGE, Donna , FOLEY, Nick , GLENCROSS, James , SHEPHERD, David , SIEH, Zara , PRICE, David, M., D.
IPC分类号： A61B5/00 , A61K38/28
CPC分类号： A61M5/315 , A61B5/002 , A61B5/14532 , A61M5/24 , A61M5/3129 , A61M5/3146 , A61M5/31525 , A61M5/31551 , A61M2005/3126 , A61M2005/3142 , A61M2205/14 , A61M2205/18 , A61M2205/215 , A61M2205/3317 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/52 , A61M2205/581 , A61M2205/583 , A61M2205/584 , A61M2205/6054 , A61M2205/6081 , A61M2205/8212 , A61M2209/04 , G01D5/1655 , G06F19/00 , G06F19/3468
摘要： Various embodiments of a "smart" drug delivery system are provided which includes an add-on module and a reusable or disposable drug pen in conjunction with a data management unit(s) DMU. Upon attachment to the pen, the add-on module may: determine dosage selected, injection of selected dosage, duration of injection, time of injection, whether the pen has been primed or shaken to thoroughly mix up insulin mixtures, transmit information relating to insulin dosage and injection to a data management unit, provide reminders, error warning or messages on improper usage or reusage of needles, track amount of drug remaining on board the pen or duration of usage of pen with respect to expiry of the drug on board, or provide an audible alarm for locating misplaced pen and module. Methods of using the drug delivery system are also described.
摘要翻译：提供了“智能”药物递送系统的各种实施例，其包括与数据管理单元DMU结合的附加模块和可重复使用或一次性药物笔。附加模块可以：确定所选择的剂量，所选剂量的注射，注射持续时间，注射时间，笔是否被引发或摇动以充分混合胰岛素混合物，传输与胰岛素相关的信息剂量和注射到数据管理单元，提供提醒，错误警告或关于不正确使用或重复使用针头的信息，轨道上留下的药物量或笔的使用持续时间，以及在药物到期时的使用时间，或提供用于定位放错的笔和模块的声音报警器。还描述了使用药物递送系统的方法。

2. 发明申请

WO2010098928A1 DRUG DELIVERY SYSTEM 审中-公开
标题翻译：药物递送系统
公开(公告)号：WO2010098928A1
公开(公告)日：2010-09-02
申请号：PCT/US2010/022241
申请日：2010-01-27
申请人： LIFESCAN, INC. , KRULEVITCH, Peter , WILK, Robert , KRAFT, Ulrich , SAVAGE, Donna , FOLEY, Nick , GLENCROSS, James , SHEPHERD, David , SIEH, Zara
发明人： KRULEVITCH, Peter , WILK, Robert , KRAFT, Ulrich , SAVAGE, Donna , FOLEY, Nick , GLENCROSS, James , SHEPHERD, David , SIEH, Zara
IPC分类号： A61M5/315
CPC分类号： A61M5/315 , A61B5/002 , A61B5/14532 , A61M5/24 , A61M5/3129 , A61M5/3146 , A61M5/31525 , A61M5/31551 , A61M2005/3126 , A61M2005/3142 , A61M2205/14 , A61M2205/18 , A61M2205/215 , A61M2205/3317 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/52 , A61M2205/581 , A61M2205/583 , A61M2205/584 , A61M2205/6054 , A61M2205/6081 , A61M2205/8212 , A61M2209/04 , G01D5/1655 , G06F19/00 , G06F19/3468
摘要： Various embodiments of a "smart" drug delivery system are provided which includes an add-on module and a reusable or disposable drug pen. Upon attachment to the pen, the add-on module may: determine dosage selected, injection of selected dosage, duration of injection, time of injection, whether the pen has been primed or shaken to thoroughly mix up insulin mixtures, transmit information relating to insulin dosage and injection to a data management unit, provide reminders, error warning or messages on improper usage or reusage of needles, track amount of drug remaining on board the pen or duration of usage of pen with respect to expiry of the drug on board, or provide an audible alarm for locating misplaced pen and module.
摘要翻译：提供了“智能”药物递送系统的各种实施例，其包括附加模块和可重复使用或一次性药物笔。附加模块可以：确定所选择的剂量，所选剂量的注射，注射持续时间，注射时间，笔是否被引发或摇动以充分混合胰岛素混合物，传输与胰岛素相关的信息剂量和注射到数据管理单元，提供提醒，错误警告或关于不正确使用或重复使用针头的信息，轨道上留下的药物量或笔的使用持续时间，以及在药物到期时的使用时间，或提供用于定位放错的笔和模块的声音报警器。

3. 发明申请

WO2010098927A1 MEDICAL MODULE FOR DRUG DELIVERY PEN 审中-公开
标题翻译：药物输送笔的医疗模块
公开(公告)号：WO2010098927A1
公开(公告)日：2010-09-02
申请号：PCT/US2010/022236
申请日：2010-01-27
申请人： LIFESCAN, INC. , KRULEVITCH, Peter , WILK, Robert , KRAFT, Ulrich , SAVAGE, Donna , FOLEY, Nick , GLENCROSS, James , SHEPHERD, David , SIEH, Zara
发明人： KRULEVITCH, Peter , WILK, Robert , KRAFT, Ulrich , SAVAGE, Donna , FOLEY, Nick , GLENCROSS, James , SHEPHERD, David , SIEH, Zara
IPC分类号： A61M5/315
CPC分类号： A61M5/315 , A61B5/002 , A61B5/14532 , A61M5/24 , A61M5/3129 , A61M5/3146 , A61M5/31525 , A61M5/31551 , A61M2005/3126 , A61M2005/3142 , A61M2205/14 , A61M2205/18 , A61M2205/215 , A61M2205/3317 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/52 , A61M2205/581 , A61M2205/583 , A61M2205/584 , A61M2205/6054 , A61M2205/6081 , A61M2205/8212 , A61M2209/04 , G01D5/1655 , G06F19/00 , G06F19/3468
摘要： Various embodiments of a medical module are provided which includes a primary module housing, a secondary module housing, a dosage sensor, a power source, and a microcontroller. The module is configured to be attached to a disposable drug delivery pen or a reusable drug delivery pen so that the module may: determine dosage selected, injection of selected dosage, duration of injection, time of injection, whether the pen has been primed or shaken to thoroughly mix up insulin mixtures, transmit information relating to insulin dosage and injection to a data management unit, provide reminders, error warning or messages on improper usage or reusage of needles, track amount of drug remaining on board the pen or duration of usage of pen with respect to expiry of the drug on board, or provide an audible alarm for locating misplaced pen and module.
摘要翻译：提供了包括主模块外壳，次模块外壳，剂量传感器，电源和微控制器的医疗模块的各种实施例。模块被配置为附接到一次性药物输送笔或可重复使用的药物递送笔，使得模块可以：确定所选择的剂量，所选剂量的注射，注射持续时间，注射时间，是否已经被注射或摇动彻底混合胰岛素混合物，将与胰岛素剂量和注射相关的信息传输到数据管理单元，提供提醒，错误警告或关于不当使用或重复使用针头的消息，跟踪笔上留下的药物的量或使用持续时间关于药物到期的笔，或提供用于定位放错的笔和模块的声音报警器。

4. 发明申请

WO2010009382A2 ANALYTE MEASUREMENT AND MANAGEMENT DEVICE AND ASSOCIATED METHODS 审中-公开
标题翻译：分析测量和管理设备及相关方法
公开(公告)号：WO2010009382A2
公开(公告)日：2010-01-21
申请号：PCT/US2009/050971
申请日：2009-07-17
申请人： LIFESCAN, INC. , SIEH, Zara , HORWITZ, David , PRICE, David , KRULEVITCH, Peter , SAVAGE, Donna , SHARTLE, Robert
发明人： SIEH, Zara , HORWITZ, David , PRICE, David , KRULEVITCH, Peter , SAVAGE, Donna , SHARTLE, Robert
IPC分类号： A61B5/00 , G06F3/048 , H04L9/32 , G08B1/08 , G06F15/16 , G06N5/02
CPC分类号： A61B5/4839 , A61B5/14532 , G06F19/00 , G06F19/3418 , G06F19/3468 , G16H40/63
摘要： Various embodiments of a diabetes management system are provided. One exemplary system may include an analyte measurement device and a therapeutic agent delivery device. The measurement device includes a measurement unit, display, and first wireless module. The therapeutic agent delivery device has a delivery device housing, delivery mechanism disposed in the housing that delivers a dosage of the agent to the user upon actuation by the user or health care provider, and a second wireless module. The second module, automatically, without prompting from a user or any active input or action by the user, transmits a signal to the first wireless module indicative of: (a) type of therapeutic agent delivered; and (b) amount of therapeutic agent delivered to the user; or (c) type of therapeutic agent device from which the therapeutic agent was administered. Also described are diabetes management devices and methods.
摘要翻译：提供了糖尿病管理系统的各种实施例。一个示例性系统可以包括分析物测量装置和治疗剂递送装置。测量装置包括测量单元，显示器和第一无线模块。治疗剂递送装置具有输送装置壳体，设置在壳体中的输送机构，其在用户或医疗保健提供者致动时将剂量的剂量递送给使用者，以及第二无线模块。自动地，第二模块在不提示用户或用户的任何有效输入或动作的情况下，向第一无线模块发送指示：（a）递送的治疗剂的类型; 和（b）递送给使用者的治疗剂量; 或（c）施用治疗剂的治疗剂装置的类型。还描述了糖尿病管理装置和方法。

5. 发明申请

WO2008157212A1 FLEXIBLE CANNULA OR MEDICAL DEVICE CONDUIT 审中-公开
标题翻译：柔性肛门或医疗器械导管
公开(公告)号：WO2008157212A1
公开(公告)日：2008-12-24
申请号：PCT/US2008/066667
申请日：2008-06-12
申请人： LIFESCAN, INC. , CORDIS CORPORATION , KRULEVITCH, Peter , OLSON, Lorin, P. , SIEH, Zara , SAVAGE, Donna , CICHOCKI, Frank, R.
发明人： KRULEVITCH, Peter , OLSON, Lorin, P. , SIEH, Zara , SAVAGE, Donna , CICHOCKI, Frank, R.
IPC分类号： A61M5/158 , A61M5/32 , A61M25/00
CPC分类号： A61M5/158 , A61M5/3275 , A61M5/329 , A61M25/0009 , A61M25/0068 , A61M25/007 , A61M2005/1585 , A61M2005/1587 , A61M2205/0266
摘要： A flexible cannula of medical device conduit (1300) includes an elongated framework (1302) formed from a flexible material (e.g., Nitinol) with a body portion, sharp head (1310), distal end ans proximal end. The flexible medical device conduit also includes a flexible tube (1314) at least partially jacketing the elongated framework between the distal end and the proximal end. Moreover, the sharp head is disposed at the distal end and is configured for subcutaneous skin insertion and the elongated framework and flexible tube define at least one conduit (1315) between the elongated framework and the flexible tube, the conduit having an opening at the distal end.
摘要翻译：医疗器械导管（1300）的柔性套管包括由柔性材料（例如镍钛诺）形成的细长骨架（1302），其具有主体部分，尖头（1310），远端和近端。柔性医疗装置导管还包括柔性管（1314），该柔性管至少部分地将细长骨架夹在远端和近端之间。此外，尖头设置在远端并且构造成用于皮下皮肤插入，并且细长骨架和柔性管限定细长框架和柔性管之间的至少一个导管（1315），所述导管在远端处具有开口结束。

6. 发明申请

WO2009137661A1 ANALYTE MEASUREMENT AND MANAGEMENT DEVICE AND ASSOCIATED METHODS 审中-公开
标题翻译：分析测量和管理设备及相关方法
公开(公告)号：WO2009137661A1
公开(公告)日：2009-11-12
申请号：PCT/US2009/043125
申请日：2009-05-07
申请人： LIFESCAN, INC. , SIEH, Zara , HORWITZ, David , PRICE, David , KRULEVITCH, Peter , SAVAGE, Donna , SHARLTE, Robert
发明人： SIEH, Zara , HORWITZ, David , PRICE, David , KRULEVITCH, Peter , SAVAGE, Donna , SHARLTE, Robert
IPC分类号： A61B5/00 , A61M5/172
CPC分类号： A61B5/4839 , A61B5/14532 , A61M5/14244 , A61M5/1723 , A61M2005/14208 , G06F19/00
摘要： A method for measuring and managing an analyte (e.g., blood glucose) in a bodily fluid includes storing a therapeutic administration protocol in a memory module of an analyte measurement and management device and measuring the analyte in the bodily fluid sample using an analyte measurement module of the device. The method also includes calculating, with a processor module of the device, a recommended therapeutic agent dosage (for example, an insulin dosage) and a recommended administration time for user-activated delivery of the dosage by employing the therapeutic administration protocol. The method further includes displaying the recommended therapeutic agent dosage and administration time to a user on a visual display of the device, delivering a therapeutic agent dosage to the user via a user-activated therapeutic agent delivery device, and detecting the user-activated administration of the therapeutic agent using a delivery device communication module of the device. In addition, the method includes communicating the aforementioned detection to the processor module and/or memory module using the delivery device communication module. The method employs analyte measurement, memory, processor, and delivery device modules, as well as a visual display, and user interface that are integrated as a single hand-held unit.
摘要翻译：用于测量和管理体液中的分析物（例如，血糖）的方法包括将分析物测量和管理装置的存储器模块中的治疗性给药方案存储在体液样品中，并使用分析物测量模块装置。该方法还包括利用该设备的处理器模块，通过使用治疗性给药方案来计算推荐的治疗剂剂量（例如，胰岛素剂量）和用户激活的剂量递送的推荐给药时间。该方法还包括在设备的视觉显示上向用户显示推荐的治疗剂剂量和给药时间，经由用户激活的治疗剂递送装置向用户递送治疗剂剂量，以及检测用户激活的给药时间所述治疗剂使用所述装置的递送装置通信模块。此外，该方法包括使用传送设备通信模块将上述检测传送到处理器模块和/或存储器模块。该方法采用分析物测量，存储器，处理器和传送设备模块，以及作为单个手持单元集成的可视显示器和用户界面。

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