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1. 发明申请

WO2012164527A1 CORRECTING THE STATIC MAGNETIC FIELD OF AN MRI RADIOTHERAPY APPARATUS 审中-公开
标题翻译：矫正MRI放射治疗装置的静态磁场
公开(公告)号：WO2012164527A1
公开(公告)日：2012-12-06
申请号：PCT/IB2012/052752
申请日：2012-05-31
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , AMTHOR, Thomas, Erik , OVERWEG, Johannes, Adrianus
发明人： AMTHOR, Thomas, Erik , OVERWEG, Johannes, Adrianus
IPC分类号： G01R33/48 , A61N5/10
CPC分类号： G01R33/56 , A61N5/1049 , A61N2005/1055 , G01R33/3873 , G01R33/3875 , G01R33/4808
摘要： A method of correcting a magnetic field of an MRI radiotherapy apparatus (300) comprising a magnetic resonance imaging system (302) and a radiation therapy system (304). The MRI system includes a magnet (306) for generating the magnetic field within an imaging zone 318. The magnet generates a magnetic field with a zero crossing (346, 404) outside of the imaging zone. The medical apparatus further comprises a gantry (332) configured for rotating a ferromagnetic component (336, 510) about a rotational axis (333). The method comprises the step of installing (100, 200) a magnetic correcting element (348, 900, 1000) located on a radial path (344, 504) perpendicular to the rotational axis. The magnetic correcting element is positioned on the radial path such that change in the magnetic field within the imaging zone due to the ferromagnetic component is reduced. The method further comprises repeatedly: measuring (102, 202, 1204) the magnetic field within the imaging zone; determining (104, 204, 1206) the change in the magnetic field in the imaging zone; and adjusting (106, 206, 1208) the position of the magnetic correcting element along the radial path if the change in the magnetic field is above a predetermined threshold.
摘要翻译：一种校正包括磁共振成像系统（302）和放射治疗系统（304）的MRI放射治疗装置（300）的磁场的方法。 MRI系统包括用于在成像区域318内产生磁场的磁体（306）。磁体在成像区域外部产生具有零交叉（346,404）的磁场。医疗设备还包括构造成围绕旋转轴线（333）旋转铁磁部件（336,510）的台架（332）。该方法包括安装（100,200）位于垂直于旋转轴线的径向路径（344,504）上的磁性校正元件（348,900,1000）的步骤。磁性校正元件位于径向路径上，使得由于铁磁性部件而导致的成像区域内的磁场的变化减小。该方法还包括：重复地：测量（102,202,1204）成像区域内的磁场; 确定（104,204,1206）所述成像区域中的磁场的变化; 以及如果所述磁场的变化高于预定阈值，则调整所述磁修正元件沿所述径向路径的位置（106,206,1208）。

2. 发明申请

WO2011145029A1 MAGNETIC RESONANCE IMAGING GRADIENT COIL, MAGNET ASSEMBLY, AND SYSTEM 审中-公开
标题翻译：磁共振成像梯度线圈，磁铁组件和系统
公开(公告)号：WO2011145029A1
公开(公告)日：2011-11-24
申请号：PCT/IB2011/052102
申请日：2011-05-13
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , OVERWEG, Johannes, Adrianus
发明人： OVERWEG, Johannes, Adrianus
IPC分类号： G01R33/385
CPC分类号： G01R33/385 , G01R33/3854 , G01R33/4215
摘要： A magnetic resonance imaging magnet assembly (100) comprising: -a magnet (102) adapted for generating a main magnetic field for aligning the magnetic spins of nuclei of a subject (502) located within an imaging volume (504); and -a gradient coil (103) for generating a gradient magnetic field for spatial encoding of the magnetic resonance signal of spins of nuclei within the imaging volume, wherein the gradient coil is adapted to be mounted into the magnet, wherein the gradient coil comprises: - a first gradient coil section (112), wherein the first gradient coil section comprises a first rigid element (113), - a second gradient coil section (114), wherein the second gradient coil section also comprises a second rigid element (115), - a connecting element (116, 300, 302, 304, 400) for joining the two half gradient coils, wherein the connecting element comprises an elastic material (116), wherein the elastic material is in contact with the first rigid element and the second rigid element.
摘要翻译：一种磁共振成像磁体组件（100），包括： - 磁体（102），适于产生主磁场，用于对准位于成像体积（504）内的对象（502）的核的磁旋转; 和梯度线圈（103），用于产生用于空间编码成像体积内的核心的磁共振信号的梯度磁场，其中所述梯度线圈适于安装到所述磁体中，其中所述梯度线圈包括： - 第一梯度线圈段（112），其中所述第一梯度线圈段包括第一刚性元件（113）， - 第二梯形线圈段（114），其中所述第二梯形线圈段还包括第二刚性元件（115）， - 用于连接所述两个半梯度线圈的连接元件（116,300,302,304,400），其中所述连接元件包括弹性材料（116），其中所述弹性材料与所述第一刚性元件接触，并且第二刚性元件。

3. 发明申请

WO2011080697A2 DYNAMIC NUCLEAR POLARIZATION APPARATUS 审中-公开
标题翻译：动态核极化装置
公开(公告)号：WO2011080697A2
公开(公告)日：2011-07-07
申请号：PCT/IB2010/056092
申请日：2010-12-28
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LEUSSLER, Christoph , WIRTZ, Daniel , BOERNERT, Peter , KEUPP, Jochen , EGGERS, Holger , DAVID, Bernd , OVERWEG, Johannes, Adrianus , ECKART, Rainer
发明人： LEUSSLER, Christoph , WIRTZ, Daniel , BOERNERT, Peter , KEUPP, Jochen , EGGERS, Holger , DAVID, Bernd , OVERWEG, Johannes, Adrianus , ECKART, Rainer
IPC分类号： G01R33/28
CPC分类号： G01R33/62 , G01R33/282 , G01R33/5601 , G01R33/5605 , G01R33/5608 , G01R33/56366 , G01R33/56383
摘要： The invention relates to a dynamic nuclear polarization apparatus (116) for continuous provision of hyperpolarized samples (114) comprising dynamically nuclear polarized nuclear spins, the apparatus (116) comprising a polarization region (106) for polarization of said nuclear spins resulting in said hyperpolarized samples, wherein the apparatus (116) further comprises: a cryostat (102) for cooling the samples (114) in the polarization region (106), a magnet (100) for providing a magnetic field to the cooled samples in the polarization region (106), a radiation source (112) for concurrently to the magnetic field provision providing a nuclear polarizing radiation to the polarization region (106) for receiving the hyperpolarized samples, a sample transport system (104) for continuously receiving unpolarized samples (114), transporting the unpolarized samples to the polarization region (106) for nuclear spin polarization and providing the resulting hyperpolarized samples (114).
摘要翻译：本发明涉及用于连续提供包含动态核极化核自旋的超极化样本（114）的动态核极化装置（116），所述装置（116）包括用于所述核自旋的极化的偏振区域（106），导致所述超极化样品，其中所述设备（116）还包括：用于冷却所述偏振区域（106）中的样品（114）的低温恒温器（102），用于向所述偏振区域中的所述冷却样品提供磁场的磁体（100） 106），用于与磁场提供同时提供用于接收超极化样本的偏振区域（106）的核偏振辐射的辐射源（112），用于连续接收非偏振样本（114）的样本传输系统（104）将非偏振样品运送到用于核自旋极化的偏振区域（106），并提供所得到的超极化样品（114）。

4. 发明申请

WO2011042820A1 RETROSPECTIVE CALCULATION OF RADIATION DOSE AND IMPROVED THERAPY PLANNING 审中-公开
标题翻译：辐射剂量的改进计算和改进的治疗方案
公开(公告)号：WO2011042820A1
公开(公告)日：2011-04-14
申请号：PCT/IB2010/054189
申请日：2010-09-16
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , NIELSEN, Tim , BOERNERT, Peter , UHLEMANN, Falk , OVERWEG, Johannes, Adrianus
发明人： NIELSEN, Tim , BOERNERT, Peter , UHLEMANN, Falk , OVERWEG, Johannes, Adrianus
IPC分类号： G01R33/381 , G01R33/48 , A61N5/10 , A61B5/055
CPC分类号： A61N5/1071 , A61N5/1031 , A61N5/1039 , A61N5/1049 , A61N2005/1055 , A61N2005/1058 , G01R33/3806 , G01R33/381 , G01R33/4808 , G01R33/5601
摘要： A combined magnetic resonance (MR) and radiation therapy system (10) includes a bore-type magnet (12) with a magnet radiation translucent region (16) which allows radiation beams to travel radially through the magnet and a split-type gradient coil (18) includes a gradient coil radiation translucent region (20) aligned to the magnet radiation translucent region (16). A radiation source (24), disposed laterally to the magnet, administers a radiation dose through the magnet and gradient coil radiation translucent regions (16, 20) to an examination region (14). A dosage unit (66) determines the actual radiation dose delivered to each voxel of a target volume (30) and at least one non-target volume based on a pre-treatment, intra-treatment, and/or post-treatment image representation of the target volume (30) and the at least one non-target volume. A planning processor (60) updates at least one remaining radiation dose of a radiation therapy plan based on the determined actual radiation dose.
摘要翻译：组合磁共振（MR）和放射治疗系统（10）包括具有磁体辐射半透明区域（16）的孔型磁体（12），其允许辐射束径向穿过磁体和分离式梯度线圈 18）包括与磁体辐射半透明区域（16）对准的梯度线圈辐射半透明区域（20）。辐射源（24）横向设置在磁体上，通过磁体和梯度线圈辐射半透明区域（16,20）将辐射剂量施加到检查区域（14）。剂量单元（66）基于预处理，治疗前和/或后处理图像表示来确定递送到目标体积（30）的每个体素的实际辐射剂量和至少一个非目标体积目标体积（30）和至少一个非目标体积。计划处理器（60）基于所确定的实际辐射剂量更新辐射治疗计划的至少一个剩余辐射剂量。

5. 发明申请

WO2010150209A1 A HYPERPOLARIZED CONTRAST AGENT DISPENSER FOR MAGNETIC RESONANCE IMAGING 审中-公开
标题翻译：用于磁共振成像的超高对比度对比剂分配器
公开(公告)号：WO2010150209A1
公开(公告)日：2010-12-29
申请号：PCT/IB2010/052864
申请日：2010-06-23
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LEUSSLER, Christoph , BOERNERT, Peter , WIRTZ, Daniel , DAVID, Bernd , EGGERS, Holger , KEUPP, Jochen , OVERWEG, Johannes, Adrianus , ECKART, Rainer
发明人： LEUSSLER, Christoph , BOERNERT, Peter , WIRTZ, Daniel , DAVID, Bernd , EGGERS, Holger , KEUPP, Jochen , OVERWEG, Johannes, Adrianus , ECKART, Rainer
IPC分类号： A61M16/10
CPC分类号： A61M16/10 , A61B5/055 , A61M16/14 , A61M2016/0015 , A61M2202/066
摘要： A dispenser (132), a magnetic resonance imaging system (100), and a method for using hyperpolarized contrast agent (304) during a magnetic resonance imaging examination. The dispenser comprises an attachment component (136) for a face piece (138). The face piece is adapted for receiving the surface of a subject (114) such that when the subject inhales hyperpolarized contrast agent enters the respiratory system of the subject. The dispenser further comprises a reservoir (300) adapted for receiving the hyperpolarized contrast agent. The dispenser further comprises a gas flow (406) tube connected to the attachment component and a vaporizer (406, 408, 412, 510, 602, 606) for vaporizing the hyperpolarized contrast agent in the gas flow tube into a hyperpolarized vapor. The dispenser further comprises a controller (402) for controlling when the vaporizer vaporizes the hyperpolarized contrast agent.
摘要翻译：分配器（132），磁共振成像系统（100）以及在磁共振成像检查期间使用超极化造影剂（304）的方法。分配器包括用于面件（138）的附接部件（136）。面部件适于接纳被检体（114）的表面，使得当受试者吸入超极化造影剂进入受试者的呼吸系统时。分配器还包括适于接收超极化造影剂的贮存器（300）。分配器还包括连接到附接部件的气流（406）管和用于将气体流管中的超极化造影剂蒸发成超极化蒸气的蒸发器（406,408,412,510,602,606）。分配器还包括控制器（402），用于控制蒸发器何时蒸发超极化造影剂。

6. 发明申请

WO2012077064A1 SLIP RING ASSEMBLY 审中-公开
标题翻译： SLIP环组件
公开(公告)号：WO2012077064A1
公开(公告)日：2012-06-14
申请号：PCT/IB2011/055508
申请日：2011-12-07
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , OVERWEG, Johannes, Adrianus
发明人： OVERWEG, Johannes, Adrianus
IPC分类号： A61B5/055 , H01R39/08 , H02K13/00 , A61N5/00 , A61B6/00
CPC分类号： H01R39/08 , A61B5/0035 , A61B5/055 , A61B6/032 , A61B6/4417 , A61B6/56 , A61N5/1081 , A61N2005/1055 , G01R33/36 , G01R33/4808 , G01R33/4812 , H01R2201/12
摘要： A medical apparatus (600) including: a magnetic resonance imaging system (602), a medical device (634), and a slip ring assembly (400, 500) for supplying electrical power to the medical device. The slip ring assembly includes: a cylindrical body (100), a rotating member (402) for rotating the medical device, a first cylindrical conductor attached to the cylindrical body, a second cylindrical conductor (108), a first set of conductive elements (112, 712) connected to the second cylindrical conductor; and a brush assembly (406) comprising a first brush (302) and a second brush (304). The first brush is operable to contact the first cylindrical conductor. The second brush is operable to contact the set of conductive elements. The first and second cylindrical conductive elements overlap at least partially. The second cylindrical conductor is connected to the cylindrical body. The first cylindrical conductor and the second cylindrical conductors are electrically isolated.
摘要翻译：一种医疗设备（600），包括：磁共振成像系统（602），医疗设备（634）和用于向医疗设备供电的滑环组件（400,500）。滑环组件包括：圆柱体（100），用于旋转医疗装置的旋转构件（402），附接到圆柱体的第一圆柱形导体，第二圆柱形导体（108），第一组导电元件 112,712）连接到第二圆柱形导体; 和包括第一刷（302）和第二刷（304）的刷组件（406）。第一刷可操作以接触第一圆柱形导体。第二刷可操作以接触该组导电元件。第一和第二圆柱形导电元件至少部分重叠。第二圆柱形导体连接到圆柱体。第一圆柱形导体和第二圆柱形导体是电隔离的。

7. 发明申请

WO2011086477A1 THERAPEUTIC APPARATUS 审中-公开
标题翻译：治疗设备
公开(公告)号：WO2011086477A1
公开(公告)日：2011-07-21
申请号：PCT/IB2011/050038
申请日：2011-01-05
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KATSCHER, Ulrich , LIPS, Oliver , FINDEKLEE, Christian , LEUSSLER, Christoph , NEHRKE, Kay , WIRTZ, Daniel , OVERWEG, Johannes, Adrianus
发明人： KATSCHER, Ulrich , LIPS, Oliver , FINDEKLEE, Christian , LEUSSLER, Christoph , NEHRKE, Kay , WIRTZ, Daniel , OVERWEG, Johannes, Adrianus
IPC分类号： A61N7/02 , A61N1/40 , A61N5/10 , A61B17/00 , A61B19/00
CPC分类号： A61N5/1064 , A61B2017/00084 , A61B2090/374 , A61N1/403 , A61N5/10 , A61N5/1084 , A61N7/00 , A61N7/02 , A61N2005/007 , A61N2005/1055 , G01R33/4804 , G01R33/4808
摘要： The invention provides for a therapeutic apparatus comprising a tissue heating system (302, 480, 482). The therapeutic apparatus further comprises a magnetic resonance imaging system (300) for acquiring magnetic resonance thermometry data (366) from nuclei of a subject (318) located within an imaging volume (330). The therapeutic apparatus further comprises a radiation therapy system (304, 592) for irradiating an irradiation volume (316, 516) of the subject, wherein the irradiation volume is within the imaging volume. The therapeutic apparatus further comprises a controller (354) for controlling the therapeutic apparatus. The controller is adapted for acquiring (100, 210) magnetic resonance thermometry data repeatedly using the magnetic resonance imaging system. The controller is adapted for heating (102, 208) at least the irradiation volume using the tissue heating system. The heating is controlled using the magnetic resonance thermometry data. The controller is adapted for irradiating (104, 208) the irradiation volume.
摘要翻译：本发明提供一种包括组织加热系统（302,480,482）的治疗设备。治疗装置还包括用于从位于成像体积（330）内的对象（318）的核获取磁共振测温数据（366）的磁共振成像系统（300）。治疗装置还包括用于照射受试者的照射体积（316,516）的放射治疗系统（304,592），其中照射体积在成像体积内。治疗装置还包括用于控制治疗仪的控制器（354）。控制器适于使用磁共振成像系统重复地获取（100,210）磁共振测温数据。控制器适于使用组织加热系统加热（102,208）至少照射体积。使用磁共振测温数据来控制加热。控制器适于照射（104,208）照射体积。

8. 发明申请

WO2013068921A1 ELECTRONIC BRACHYTHERAPY SOURCE FOR USE IN /NEAR MR SCANNERS 审中-公开
标题翻译：用于/附近扫描仪的电子浏览源
公开(公告)号：WO2013068921A1
公开(公告)日：2013-05-16
申请号：PCT/IB2012/056190
申请日：2012-11-06
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH
发明人： AMTHOR, Thomas, Erik , WEISS, Steffen , OVERWEG, Johannes, Adrianus
IPC分类号： A61N5/10
CPC分类号： G01R33/287 , A61N5/1001 , A61N5/1007 , A61N5/1039 , A61N2005/1022 , A61N2005/1055 , A61N2005/1089 , A61N2005/1094 , G01R33/48
摘要： A miniature X-ray source (10) for high dose rate brachytherapy that can be operated in a wide range of operating directions (76) in the presence of a strong magnetic field (B), such as, for instance, the static magnetic field (B) of an MR scanner, with at least one anode (12) and at least one cathode (14), wherein in an operative state, an electric field (18) between the anode (12) and the cathode (14) is essentially spherically symmetric in at least a continuous solid angle of more than π/2 sr about a center (16) of the cathode (14); a brachytherapy system, comprising at least one said miniature X-ray source (10), and a method for generating a beam (82) of X-ray radiation inside an outer magnetic field (B) or an operative MR scanner with said miniature X-ray source (10).
摘要翻译：一种用于高剂量率近程放射治疗的微型X射线源（10），其可以在强磁场（B）的存在下在宽范围的操作方向（76）下操作，例如静态磁场（12）和至少一个阴极（14）的MR扫描器（B），其中在工作状态下，阳极（12）和阴极（14）之间的电场（18）是在阴极（14）的中心（16）上至少相对于pi / 2 sr的连续立体角基本上球形对称; 包括至少一个所述微型X射线源（10）的近距离放射治疗系统，以及用于在外部磁场（B）或具有所述微型X的操作MR扫描器中产生X射线辐射束（82）的方法射源（10）。

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