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1. 发明申请

WO2008096285A2 MOTION ESTIMATION IN TREATMENT PLANNING 审中-公开
标题翻译：治疗计划运动估计
公开(公告)号：WO2008096285A2
公开(公告)日：2008-08-14
申请号：PCT/IB2008/050279
申请日：2008-01-25
申请人： KONINKLIJKE PHILIPS ELECTRONICS, N.V. , BRINKS, Ralph , MEYER, Carsten , FISCHER, Alexander , GAGNON, Daniel , BUSCH, Marc
发明人： BRINKS, Ralph , MEYER, Carsten , FISCHER, Alexander , GAGNON, Daniel , BUSCH, Marc
IPC分类号： A61B6/03
CPC分类号： A61B6/032 , A61B5/055 , A61B5/721 , A61B5/7289 , A61B6/037 , A61B6/527 , A61N5/103 , A61N5/1037 , A61N5/1067 , A61N2005/1052
摘要： An apparatus includes a scanner (102, 104) and a scanning motion monitor (100). A motion modeler (116) uses data from the scanning motion monitor (100) and the scanner (102, 104) to generate a motion model which describes motion of a region of interest of an object. A treatment planner (112) uses image data from the scanner (102, 104) to establish a treatment plan for the object. A treatment device 114, which operates in conjunction with a treatment motion monitor (108), uses the motion model to compensate for motion of the object during application of the treatment.
摘要翻译：一种装置包括扫描仪（102,104）和扫描运动监视器（100）。运动建模器（116）使用来自扫描运动监视器（100）和扫描器（102,104）的数据来生成描述对象感兴趣区域的运动的运动模型。治疗计划器（112）使用来自扫描器（102,104）的图像数据来建立对象的治疗计划。与治疗运动监视器（108）一起操作的治疗装置114使用运动模型来补偿在施用治疗期间物体的运动。

2. 发明申请

WO2009153683A3 RADIOLOGICAL IMAGING INCORPORATING LOCAL MOTION MONITORING, CORRECTION, AND ASSESSMENT 审中-公开
公开(公告)号：WO2009153683A3
公开(公告)日：2009-12-23
申请号：PCT/IB2009/052297
申请日：2009-06-01
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BRINKS, Ralph , FISCHER, Alexander , MARTIN RECUERO, Ana, Belen , GEORGI, Jens-Christoph , SCHWEIZER, Bernd , PAULUS, Timo, Markus
发明人： BRINKS, Ralph , FISCHER, Alexander , MARTIN RECUERO, Ana, Belen , GEORGI, Jens-Christoph , SCHWEIZER, Bernd , PAULUS, Timo, Markus
IPC分类号： G06T11/00
摘要： A radiological imaging method comprises: acquiring radiological lines of response (LOR's) from a subject; grouping the acquired LOR's into time intervals such that each group of LOR's (20) was acquired during a selected time interval; identifying a region of interest (60, 74) for each time interval based on LOR's grouped into that time interval; for each time interval, determining a positional characteristic (102) of the region of interest identified for that time interval based on LOR's grouped into that time interval; for each time interval, spatially adjusting LOR's grouped into that time interval based on the positional characteristic of the region of interest identified for that time interval; and reconstructing at least the spatially adjusted LOR's to generate a motion compensated reconstructed image.

3. 发明申请

WO2007046013A2 PATIENT SCAN TIME OPTIMIZATION FOR PET/SPECT IMAGING 审中-公开
标题翻译：患者扫描时间优化PET / SPECT成像
公开(公告)号：WO2007046013A2
公开(公告)日：2007-04-26
申请号：PCT/IB2006/053317
申请日：2006-09-15
申请人： KONINKLIJKE PHILIPS ELECTRONICS, N.V. , NARAYANAN, Manoj , BAKKER, Bart , GAGNON, Daniel , FISCHER, Alexander , SPIES, Lothar
发明人： NARAYANAN, Manoj , BAKKER, Bart , GAGNON, Daniel , FISCHER, Alexander , SPIES, Lothar
CPC分类号： A61B6/00 , A61B6/037
摘要： An imaging system (10) comprises a data device (30), which controls radiation data acquisition from a subject positioned in an examination region (18) for an examination. A rebinning processor (40) bins the acquired data periodically into a histogram (42). A transform (70) transforms the histogram (42) into individual independent or uncorrelated components, each component including a signal content and a noise content. A stopping determining device (52) compares an aspect of at least one selected component to a predetermined threshold (TH) and, based on the comparison, terminates the data acquisition.
摘要翻译：成像系统（10）包括数据装置（30），其控制从位于检查区域（18）中的被摄体进行检查的辐射数据采集。重组处理器（40）将获取的数据周期性地存储到直方图（42）中。变换（70）将直方图（42）变换为独立的或不相关的分量，每个分量包括信号内容和噪声内容。停止确定装置（52）将至少一个所选择的组件的方面与预定阈值（TH）进行比较，并且基于该比较，终止数据采集。

4. 发明申请

WO2007136968A2 ERROR ADAPTIVE FUNCTIONAL IMAGING 审中-公开
标题翻译：错误自适应功能成像
公开(公告)号：WO2007136968A2
公开(公告)日：2007-11-29
申请号：PCT/US2007/067848
申请日：2007-05-01
申请人： KONINKLIJKE PHILIPS ELECTRONICS, N.V. , U.S. PHILIPS CORPORATION , FISCHER, Alexander , SPIES, Lothar , MEYER, Carsten
发明人： FISCHER, Alexander , SPIES, Lothar , MEYER, Carsten
IPC分类号： G06T5/00
CPC分类号： G06T7/11 , G06K9/6218 , G06T2207/10104 , G06T2207/20016 , G06T2207/20021 , G06T2207/30096
摘要： A method for use in functional medical imaging includes adaptively partitioning functional imaging data as a function of a spatially varying error model. The functional image data is partitioned according to an optimization strategy. The data may be visualized or used to plan a course of treatment. In one implementation, the image data is partitioned so as to vary its spatial resolution. In another, the number of clusters is varied based on the error model.
摘要翻译：用于功能医学成像的方法包括根据空间变化的误差模型自适应地划分功能成像数据。功能图像数据根据优化策略进行分区。数据可以被可视化或用于计划治疗过程。在一个实现中，图像数据被分割以改变其空间分辨率。另一方面，群集的数量根据误差模型而变化。

5. 发明申请

WO2010119388A1 QUANTIFICATION OF MEDICAL IMAGE DATA 审中-公开
标题翻译：医学图像数据量化
公开(公告)号：WO2010119388A1
公开(公告)日：2010-10-21
申请号：PCT/IB2010/051564
申请日：2010-04-12
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS , FISCHER, Alexander , RANJAN, Uma Satya , KUMAR, Utpal
发明人： FISCHER, Alexander , RANJAN, Uma Satya , KUMAR, Utpal
IPC分类号： G06T7/00
CPC分类号： G06T7/0012 , G06T7/30 , G06T2207/10072 , G06T2207/20104 , G06T2207/30004
摘要： A system is provided for quantification of medical image data. First image obtaining means (1) are for obtaining a first image (A). Second image obtaining means (2) are for obtaining a second image (B). Spatial transformation obtaining means (3) are for obtaining spatial transformation information representing a correspondence between points in the first image and corresponding points in the second image. Identifying means (4) are for identifying a first image region (C) in the first image (A). Transforming means (5) are for transforming the first image region (C) into a corresponding second image region (C') in the second image (B) based on the spatial transformation information. Quantification means (6) are for computing a quantification relating to the second image region (C') by accessing image values of the second image (B) within the second image region (C').
摘要翻译：提供用于定量医学图像数据的系统。第一图像获取装置（1）用于获得第一图像（A）。第二图像获取装置（2）用于获得第二图像（B）。空间变换获取装置（3）用于获得表示第一图像中的点与第二图像中的对应点之间的对应关系的空间变换信息。识别装置（4）用于识别第一图像（A）中的第一图像区域（C）。变换装置（5）用于基于空间变换信息将第一图像区域（C）变换为第二图像（B）中的对应的第二图像区域（C'）。量化装置（6）用于通过访问第二图像区域（C'）内的第二图像（B）的图像值来计算与第二图像区域（C'）有关的量化。

6. 发明申请

WO2009141768A1 MEDICAL WORKFLOW SYSTEMS AND METHODS WITH PROCESS WORKFLOW RECORDATION 审中-公开
标题翻译：医疗工作流程与流程工作流程记录方法
公开(公告)号：WO2009141768A1
公开(公告)日：2009-11-26
申请号：PCT/IB2009/051989
申请日：2009-05-13
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , RANJAN, Uma, S. , FISCHER, Alexander , BUCKLER, Andrew, J. , XIE, Shuping , RAMASWAMY, Shivakumar, Kunigal
发明人： RANJAN, Uma, S. , FISCHER, Alexander , BUCKLER, Andrew, J. , XIE, Shuping , RAMASWAMY, Shivakumar, Kunigal
IPC分类号： G06F19/00
CPC分类号： G06K9/6284 , G06F19/00 , G06F19/321 , G06Q50/24
摘要： A medical information processing and storage system includes a medical images database (30) storing medical images and metadata relevant to the medical images. A processor (60) is configured to perform post-acquisition image processing on medical images. A medical images archiver (70) is configured to store a medical image in the medical images database after the medical image has been processed by the processor. The medical images archiver stores the medical image in the database with processing-descriptive metadata that is descriptive of the post-acquisition image processing performed on the medical image by the processor.
摘要翻译：医疗信息处理和存储系统包括存储与医学图像相关的医学图像和元数据的医学图像数据库（30）。处理器（60）被配置为对医学图像执行采集后图像处理。医疗图像存档器（70）被配置为在处理器处理了医学图像之后，将医学图像存储在医学图像数据库中。医学图像存档器将医学图像存储在数据库中，其处理描述性元数据描述了由处理器对医学图像执行的采集后图像处理。

7. 发明申请

WO2008110962A1 VISUALIZATION OF PARAMETRIC MAPS 审中-公开
标题翻译：参数化可视化
公开(公告)号：WO2008110962A1
公开(公告)日：2008-09-18
申请号：PCT/IB2008/050796
申请日：2008-03-05
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , WENGLER, Mark, C. , FISCHER, Alexander
发明人： WENGLER, Mark, C. , FISCHER, Alexander
IPC分类号： G06T11/20
CPC分类号： G06T11/00
摘要： The invention discloses visualizing a plurality of parametric maps (102, 104, 106) of an area (103), the parametric maps visualizing parametric levels, the method comprising determining first regions (204, 206, 208) within the plurality of parametric maps that spatially overlap and have parametric levels which are substantially the same, and determining second regions (212, 214, 216) within the plurality of parametric maps that are spatially non-overlapping or have parametric levels which are substantially different, and visualizing a fused map (202) of the plurality of parametric maps by displaying the first regions in a predetermined first way and displaying the second regions in a predetermined second way in the fused map, in order e.g. hereby to provide an easy, fast, simple and distinctive determination of those regions where two or more maps match to each other, while also being able to see any relations between the maps.
摘要翻译：本发明公开了可视化区域（103）的多个参数图（102,104,106），所述参数地图可视化参数水平，所述方法包括确定所述多个参数图内的第一区域（204,206,208），其中在空间上重叠并且具有基本上相同的参数水平，以及确定空间不重叠或具有基本不同的参数水平的多个参数图内的第二区域（212,214,216），以及可视化融合图（ 202），通过以预定的第一方式显示第一区域并以融合地图中的预定第二方式显示第二区域，以便按照例如因此，对于两个或多个地图彼此匹配的地区，同时也能够看到地图之间的任何关系，为这些地区提供一个简单，快速，简单和独特的决定。

8. 发明申请

WO2008015625A2 METHOD OF REARRANGING A CLUSTER MAP OF VOXELS IN AN IMAGE 审中-公开
标题翻译：在图像中重新定位VOXELS的聚类映射的方法
公开(公告)号：WO2008015625A2
公开(公告)日：2008-02-07
申请号：PCT/IB2007/052996
申请日：2007-07-30
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , WENGLER, Mark, C. , FISCHER, Alexander
发明人： WENGLER, Mark, C. , FISCHER, Alexander
IPC分类号： G06T7/00
CPC分类号： G06K9/6218 , G06K9/033 , G06K9/38 , G06T7/11 , G06T7/136 , G06T7/143 , G06T2200/04 , G06T2207/10072 , G06T2207/20036 , G06T2207/30004
摘要： This invention relates to rearranging a cluster map of voxels in an image aiming at the reduction of sub-cluster scatter. The cluster map that includes two or more cluster levels is displayed to the user along with the distribution of the voxels within each respective cluster levels. The aim is to enable the user to evaluate the quality of the cluster map and based on the evaluation to change the distribution of the voxels. Such a change in the distribution will result in an update of the cluster map.
摘要翻译：本发明涉及重新排列旨在减少子群落散射的图像中的体素的聚类映射。包含两个或多个集群级别的集群映射与每个相应集群级别中的体素分布一起显示给用户。目的是使用户能够评估集群映射的质量，并根据评估改变体素的分布。分配的这种变化将导致集群映射的更新。

9. 发明申请

WO2007010440A2 AUTOMATIC INPUT FUNCTION ESTIMATION FOR PHARMACOKINETIC MODELING 审中-公开
标题翻译：用于药物动力学建模的自动输入函数估计
公开(公告)号：WO2007010440A2
公开(公告)日：2007-01-25
申请号：PCT/IB2006/052345
申请日：2006-07-11
申请人： KONINKLIJKE PHILIPS ELECTRONICS, N.V. , U.S. PHILIPS CORPORATION , FISCHER, Alexander , PAULUS, Timo
发明人： FISCHER, Alexander , PAULUS, Timo
IPC分类号： G06F19/00
CPC分类号： G06F17/18 , G16H50/50
摘要： This system (200), apparatus (300), and method (100) of the present invention provide an analytic way to solve the (input) estimation problem of pharmacokinetic modeling: estimating parameters of a kinetic model from a series of tracer (radioactively labeled imaging agent) activity measurements (e.g. by positron emission tomography). Since the model describes a biological process its parameters have a direct functional interpretation (e.g. hypoxia for the tracer FMISO) that can be of diagnostic value. The measurements represent the activity distribution in time and space in the form of a 4D data set d(t, x, y, z), t = 1, . . . , T. The kinetic parameter estimation procedure (205) requires knowledge of the tracer input activity. This input activity can either be measured invasively or it can be estimated from the data in a preprocessing step. The estimation problem can be solved efficiently if the model and its input are described analytically. Typically parameterized functions (often sums of exponential terms) (204) are fitted to the averaged data over a region of interest (ROI) (e.g. an artery or the left ventricular blood pool) in order to obtain an analytical input representation. The input function representation (functional form) (204) and its initial parameter values (205) have to be selected / specified prior to the fitting procedure 206). The present invention thereby reduces the amount of manual interaction and operator dependence in the evaluation of dynamic procedures.
摘要翻译：本发明的系统（200），装置（300）和方法（100）提供了解决药代动力学模型的（输入）估计问题的分析方法：从一系列示踪剂（放射性标记）估计动力学模型的参数成像剂）活性测量（例如通过正电子发射断层摄影）。由于该模型描述了生物过程，其参数具有可以具有诊断价值的直接功能解释（例如示踪剂FMISO的缺氧）。测量以4D数据集d（t，x，y，z），t = 1，...的形式表示时间和空间中的活动分布。。。动力学参数估计程序（205）需要了解示踪者输入活动的知识。该输入活动可以被入侵测量，也可以从预处理步骤中的数据估计。如果模型及其输入被分析地描述，则可以有效地解决估计问题。通常，参数化函数（通常指数项的和）（204）适合于感兴趣区域（ROI）（例如动脉或左心室血池）上的平均数据，以便获得分析输入表示。必须在拟合程序206之前选择/指定输入功能表示（功能形式）（204）及其初始参数值（205）。因此，本发明减少了在动态过程评估中手动交互和操作者依赖的量。

10. 发明申请

WO2009019535A1 A METHOD, APPARATUS, COMPUTER-READABLE MEDIUM AND USE FOR PHARMACOKINETIC MODELING 审中-公开
标题翻译：方法，装置，计算机可读介质和用于药物动力学建模
公开(公告)号：WO2009019535A1
公开(公告)日：2009-02-12
申请号：PCT/IB2007/053065
申请日：2007-08-03
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , PAULUS, Timo , FISCHER, Alexander , SPIES, Lothar
发明人： PAULUS, Timo , FISCHER, Alexander , SPIES, Lothar
IPC分类号： G06T7/00
CPC分类号： G06T7/0016 , G06T7/207 , G06T2207/10076 , G06T2207/10104 , G06T2207/20016 , G06T2207/20021 , G06T2207/30004
摘要： An advantageous method, apparatus, computer-readable medium, and use for improving the estimation of relevant initial parameters for parameter reconstruction processes in molecular imaging are disclosed, resulting in shorter process times and more robust results with small confidence intervals.
摘要翻译：公开了一种有利的方法，装置，计算机可读介质和用于改进分子成像中参数重建过程的相关初始参数的估计的用途，导致较短的处理时间和更小的置信区间的更稳健的结果。

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