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1. 发明申请

WO2012037288A2 METHODS AND COMPOSITIONS FOR THE EXTRACELLULAR TRANSPORT OF BIOSYNTHETIC HYDROCARBONS AND OTHER MOLECULES 审中-公开
标题翻译：用于生物合成烃和其他分子的胞外运输的方法和组合物
公开(公告)号：WO2012037288A2
公开(公告)日：2012-03-22
申请号：PCT/US2011051648
申请日：2011-09-14
申请人： JOULE UNLTD TECHNOLOGIES INC , LAWRENCE CAROLYN , REPPAS NIKOS BASIL , SMITH KEVIN , SHOLL MARTHA , RIDLEY CHRISTIAN PERRY
发明人： LAWRENCE CAROLYN , REPPAS NIKOS BASIL , SMITH KEVIN , SHOLL MARTHA , RIDLEY CHRISTIAN PERRY
IPC分类号： C12N1/21 , C07K19/00 , C12N1/00 , C12N1/11 , C12N1/13 , C12N1/15 , C12N1/19
CPC分类号： C07K14/195 , C07K14/245 , C07K2319/03 , C07K2319/033 , C12N9/0004 , C12N9/0006 , C12N15/74 , C12P5/02 , C12P5/026
摘要： The present disclosure identifies methods and compositions for modifying photoautotrophic organisms as hosts, such that the organisms efficiently convert carbon dioxide and light into hydrocarbons, e.g., n-alkanes and n-alkenes, wherein the n-alkanes are secreted into the culture medium via recombinantly expressed transporter proteins. In particular, the use of such organisms for the commercial production of n-alkanes and related molecules is contemplated.
摘要翻译：本公开内容确定了用于修饰光合自养生物体作为宿主的方法和组合物，使得生物体有效地将二氧化碳和光转化为烃，例如正构烷烃和正构烷烃，其中正构烷烃通过重组分泌到培养基中表达的转运蛋白。具体而言，考虑将这些生物体用于商业生产正构烷烃和相关分子。

2. 发明申请

WO2012037288A8 METHODS AND COMPOSITIONS FOR THE EXTRACELLULAR TRANSPORT OF BIOSYNTHETIC HYDROCARBONS AND OTHER MOLECULES 审中-公开
公开(公告)号：WO2012037288A8
公开(公告)日：2012-05-10
申请号：PCT/US2011051648
申请日：2011-09-14
申请人： JOULE UNLTD TECHNOLOGIES INC , REPPAS NIKOS BASIL , LAWRENCE CAROLYN , SMITH KEVIN , SHOLL MARTHA , RIDLEY CHRISTIAN PERRY
发明人： REPPAS NIKOS BASIL , LAWRENCE CAROLYN , SMITH KEVIN , SHOLL MARTHA , RIDLEY CHRISTIAN PERRY
IPC分类号： C12N1/21 , C07K19/00 , C12N1/00 , C12N1/11 , C12N1/13 , C12N1/15 , C12N1/19
CPC分类号： C07K14/195 , C07K14/245 , C07K2319/03 , C07K2319/033 , C12N9/0004 , C12N9/0006 , C12N15/74 , C12P5/02 , C12P5/026
摘要： The present disclosure identifies methods and compositions for modifying photoautotrophic organisms as hosts, such that the organisms efficiently convert carbon dioxide and light into hydrocarbons, e.g., n-alkanes and n-alkenes, wherein the n-alkanes are secreted into the culture medium via recombinantly expressed transporter proteins. In particular, the use of such organisms for the commercial production of n-alkanes and related molecules is contemplated.

3. 发明申请

WO2012037288A3 METHODS AND COMPOSITIONS FOR THE EXTRACELLULAR TRANSPORT OF BIOSYNTHETIC HYDROCARBONS AND OTHER MOLECULES 审中-公开
标题翻译：生物碳氢化合物和其他分子的细胞运输的方法和组合物
公开(公告)号：WO2012037288A3
公开(公告)日：2012-06-28
申请号：PCT/US2011051648
申请日：2011-09-14
申请人： JOULE UNLTD TECHNOLOGIES INC , REPPAS NIKOS BASIL , LAWRENCE CAROLYN , SMITH KEVIN , SHOLL MARTHA , RIDLEY CHRISTIAN PERRY
发明人： REPPAS NIKOS BASIL , LAWRENCE CAROLYN , SMITH KEVIN , SHOLL MARTHA , RIDLEY CHRISTIAN PERRY
IPC分类号： C12P1/04 , C12P5/00
CPC分类号： C07K14/195 , C07K14/245 , C07K2319/03 , C07K2319/033 , C12N9/0004 , C12N9/0006 , C12N15/74 , C12P5/02 , C12P5/026
摘要： The present disclosure identifies methods and compositions for modifying photoautotrophic organisms as hosts, such that the organisms efficiently convert carbon dioxide and light into hydrocarbons, e.g., n-alkanes and n-alkenes, wherein the n-alkanes are secreted into the culture medium via recombinantly expressed transporter proteins. In particular, the use of such organisms for the commercial production of n-alkanes and related molecules is contemplated.
摘要翻译：本公开确定用于将光自养生物修饰为宿主的方法和组合物，使得生物有效地将二氧化碳和光转化成烃，例如正烷烃和正烯烃，其中正烷烃通过重组方式分泌到培养基中表达转运蛋白。特别地，考虑使用这种生物来商业生产正烷烃和相关分子。

4. 发明申请

WO2009017817A3 A SERVER METHOD AND SYSTEM FOR RENDERING CONTENT ON A WIRELESS DEVICE 审中-公开
标题翻译：一种用于在无线设备上呈现内容的服务器方法和系统
公开(公告)号：WO2009017817A3
公开(公告)日：2009-04-02
申请号：PCT/US2008009303
申请日：2008-07-31
申请人： HANDS ON MOBILE INC , CARION PIERRE , SMITH KEVIN
发明人： CARION PIERRE , SMITH KEVIN
IPC分类号： G06F9/44
CPC分类号： G06F9/4445 , H04M1/72525
摘要： A server implemented method for processing data for a wireless device. The server in response to a user request executes an application program for generating content for rendering on the wireless device where the content is wireless device generic. A first screen description based on the content and a device profile of the wireless device is generated. The device profile may describe a rendering capability of the wireless device. The first screen may be in a syntax generic format independent of the wireless device type and describe relative screen location and display object size information independent of screen dimensions. The first screen is translated into a second screen description that includes discrete low level rendering commands within the rendering capability of the wireless device that is syntax generic. Low level rendering commands include physical screen positions of display elements. The translated second screen is then transmitted to the wireless device.
摘要翻译：一种用于处理无线设备的数据的服务器实现的方法。响应于用户请求的服务器执行用于生成内容以在内容为无线设备通用的无线设备上呈现的应用程序。产生基于无线设备的内容和设备简档的第一屏幕描述。设备简档可以描述无线设备的呈现能力。第一屏幕可以是独立于无线设备类型的语法通用格式，并且描述与屏幕尺寸无关的相对屏幕位置和显示对象尺寸信息。第一个屏幕被翻译成第二个屏幕描述，其中包括无线设备的渲染能力中的离散低级渲染命令，这是语法通用的。低级渲染命令包括显示元素的物理屏幕位置。然后将翻译的第二屏幕发送到无线设备。

5. 发明申请

WO2012135859A3 METHOD AND APPARATUS FOR RESTRICTING FLOW THROUGH AN OPENING IN THE SIDE WALL OF A BODY LUMEN, AND/OR FOR REINFORCING A WEAKNESS IN THE SIDE WALL OF A BODY LUMEN, WHILE STILL MAINTAINING SUBSTANTIALLY NORMAL FLOW THROUGH THE BODY LUMEN 审中-公开
标题翻译：用于通过在身体壁的侧壁中打开流动来限制流动的方法和装置，和/或用于增强身体壁的侧壁中的弱点，同时维持通过身体的大量的大量正常流动
公开(公告)号：WO2012135859A3
公开(公告)日：2013-05-16
申请号：PCT/US2012031899
申请日：2012-04-02
申请人： UNIV CORNELL , RIINA HOWARD , MILSOM JEFFREY , COMHILL J FREDERICK , NGUYEN TUAN ANH , SMITH KEVIN , KEOUGH KEVIN , ANDREWS ROBERT
发明人： RIINA HOWARD , MILSOM JEFFREY , COMHILL J FREDERICK , NGUYEN TUAN ANH , SMITH KEVIN , KEOUGH KEVIN , ANDREWS ROBERT
IPC分类号： A61F2/06
CPC分类号： A61B17/12172 , A61B17/12022 , A61B17/12118 , A61B17/12131 , A61B2017/00867 , A61B2017/12054 , A61F2/82 , A61F2/86 , A61F2/91 , A61F2/95 , A61F2002/30242 , A61F2002/823 , A61F2230/005 , A61F2230/0071 , A61F2230/0091 , A61F2230/0095 , A61H23/00 , A61N5/0616 , C22F1/006
摘要： A method for making a device for causing thrombosis of an aneurysm, wherein said device comprises a single elastic filament configurable between (i) an elongated, substantially linear configuration, and (ii) a longitudinally-contracted, substantially three-dimensional configuration, said method comprising: providing a sheet of shape memory material; producing a single filament, two-dimensional interim structure from said sheet of shape memory material; mounting said single filament, two-dimensional interim structure to a fixture so that said single filament, two-dimensional interim structure is transformed into said longitudinally-contracted, substantially three-dimensional configuration; and heat treating said single filament, two- dimensional interim structure while it is mounted to said fixture so as to produce said device in its longitudinally-contracted, substantially three- dimensional configuration.
摘要翻译：一种用于制造用于引起动脉瘤血栓形成的装置的方法，其中所述装置包括在（i）细长的，基本上线性的构型和（ii）纵向收缩的基本上三维构型之间可配置的单个弹性丝，所述方法包括：提供一片形状记忆材料; 从所述形状记忆材料片产生单丝，二维中间结构; 将所述单丝，二维临时结构安装到固定装置，使得所述单丝，二维中间结构转变成所述纵向收缩的基本三维构型; 以及在安装到所述固定装置的同时对所述单丝进行热处理，二维中间结构，以便在其纵向收缩的基本三维构造中产生所述装置。

6. 发明申请

WO2012156317A3 INTRANASAL PHARMACEUTICAL DOSAGE FORMS COMPRISING NALOXONE 审中-公开
标题翻译：包含纳洛酮的内用药物剂型
公开(公告)号：WO2012156317A3
公开(公告)日：2013-05-10
申请号：PCT/EP2012058792
申请日：2012-05-11
申请人： EURO CELTIQUE SA , STRANG JOHN , OKSCHE ALEXANDER , HARRIS STEPHEN , SMITH KEVIN , MOTTIER LUCIE HELENE JEANNE
发明人： STRANG JOHN , OKSCHE ALEXANDER , HARRIS STEPHEN , SMITH KEVIN , MOTTIER LUCIE HELENE JEANNE
IPC分类号： A61K9/00 , A61K9/08 , A61K31/135 , A61P25/36
CPC分类号： A61K9/0043 , A61K9/0019 , A61K31/485 , A61K47/02
摘要： The present invention relates to an intranasal pharmaceutical dosage form comprising a dosing unit comprising naloxone or a pharmaceutically acceptable salt thereof in an amount of equivalent to >= 0.5 mg naloxone HCl dissolved in an application fluid of a volume of
摘要翻译：本发明涉及一种鼻内药物剂型，其包含包含纳洛酮或其药学上可接受的盐的剂量单位，其量相当于溶解在体积<=250μl的应用流体中的> = 0.5mg纳洛酮HCl。此外，本发明涉及用于治疗过量阿片样物质和/或其至少一种症状的鼻内药物剂型。

7. 发明申请

WO2007139790A3 TORQUE-TRANSMITTING VARIABLY-FLEXIBLE INSERTION DEVICE AND METHOD FOR TRANSMITTING TORQUE AND VARIABLY FLEXING AN INSERTION DEVICE 审中-公开
标题翻译：扭矩传递变形插入装置和传动扭矩和变形插入装置的方法
公开(公告)号：WO2007139790A3
公开(公告)日：2008-11-13
申请号：PCT/US2007012179
申请日：2007-05-22
申请人： KMS MEDICAL LLC , SMITH KEVIN , DEVILLE DEREK , KLINE KOREY , PALMER MATTHEW
发明人： SMITH KEVIN , DEVILLE DEREK , KLINE KOREY , PALMER MATTHEW
IPC分类号： A61M25/00
CPC分类号： A61B1/31 , A61B1/00135
摘要： A torque-transmitting, variably-flexible insertion device includes a hollow body having a proximal end with an entrance for receiving an instrument and a distal end with a tip for protrusion of the instrument. A vacuum-activated device transitions the hollow body between a relatively flexible condition and a relatively stiff condition. A torque braid transmits torque from the proximal end toward the distal end. A method for transmitting torque and variably flexing the insertion device includes transmitting torque along the hollow body with the torque braid, applying suction to create a vacuum in the hollow body for placing the hollow body in the relatively stiff condition, and relieving the vacuum for placing the hollow body in the relatively flexible condition.
摘要翻译：扭矩传递可变弹性插入装置包括具有近端的中空本体，其具有用于接收器械的入口和具有用于突出仪器的尖端的远端。真空激活装置在相对柔性的状态和较硬的状态之间转换中空体。扭矩编织物从近端向远端传递扭矩。用于传递扭矩并且可变地弯曲插入装置的方法包括用扭矩编织物沿中空体传递扭矩，施加抽吸以在中空体中产生真空以将中空体放置在相对较硬的状态，并且释放用于放置的真空中空体处于相对灵活的状态。

8. 发明申请

WO2008144630A3 TORQUE-TRANSMITTING, LOCKING AND RELEASING INSTRUMENT HOLDERS AND METHODS FOR OPERATING THE INSTRUMENT HOLDERS 审中-公开
标题翻译：扭矩传动，锁定和释放仪器夹具和操作仪器夹具的方法
公开(公告)号：WO2008144630A3
公开(公告)日：2009-02-05
申请号：PCT/US2008064084
申请日：2008-05-19
申请人： SYNTHEON LLC , SMITH KEVIN , PALMER MATTHEW , DEVILLE DEREK , KLINE KOREY , RIVERA CARLOS , BALES THOMAS , MENDEZ MAX , KIRK MICHAEL
发明人： SMITH KEVIN , PALMER MATTHEW , DEVILLE DEREK , KLINE KOREY , RIVERA CARLOS , BALES THOMAS , MENDEZ MAX , KIRK MICHAEL
IPC分类号： A61B1/00
CPC分类号： A61B1/00066 , A61B1/00147
摘要： A first embodiment of a torque-transmitting, locking instrument holder, includes a hollow body having a proximal end for receiving an instrument, a distal end for protrusion of the instrument, and a handle to be gripped by an operator. A device is provided for locking the handle to and unlocking the handle from the instrument at least partly disposed within the hollow body. An optionally automatically releasing, second embodiment of the instrument holder includes a grip to be held by an operator for guiding an instrument, an actuator to be activated by the operator and a biasing device exerting a force. A clamp is moved by the actuator toward the instrument against the force of the biasing device and is moved by the biasing device away from the instrument optionally upon releasing the actuator. Methods for operating the instrument holders are also provided.
摘要翻译：扭矩传递锁定仪器保持器的第一实施例包括具有用于接收仪器的近端的中空体，用于突出仪器的远端以及由操作者抓握的手柄。提供了一种装置，用于将手柄锁定到手柄上并将其从该器械上解锁，至少部分地设置在该中空体内。仪器保持器的可选地自动释放的第二实施例包括由操作者保持以用于引导仪器的手柄，由操作者激活的致动器和施加力的偏置装置。致动器的夹具抵抗偏置装置的力而朝向仪器移动，并且在释放致动器时可以通过偏置装置远离仪器移动。还提供了操作仪器支架的方法。

9. 发明申请

WO2008103797A3 ELECTRICALLY SELF-POWERED SURGICAL INSTRUMENT WITH CRYPTOGRAPHIC IDENTIFICATION OF INTERCHANGEABLE PART 审中-公开
标题翻译：电动自动手术仪器，可互换部件的识别识别
公开(公告)号：WO2008103797A3
公开(公告)日：2009-01-22
申请号：PCT/US2008054530
申请日：2008-02-21
申请人： SYNTHEON LLC , SMITH KEVIN , BALES THOMAS , DEVILLE DEREK , RIVERA CARLOS , PALMER MATTHEW
发明人： SMITH KEVIN , BALES THOMAS , DEVILLE DEREK , RIVERA CARLOS , PALMER MATTHEW
IPC分类号： A61B17/04
CPC分类号： A61B17/1155 , A61B17/07207 , A61B17/1114 , A61B17/115 , A61B90/98 , A61B2017/00084 , A61B2017/00398 , A61B2017/0046 , A61B2017/00473 , A61B2017/00734 , A61B2017/07257 , A61B2017/07271 , A61B2017/07285 , A61B2017/2943 , A61B2090/065 , A61B2090/08021 , A61B2090/0811 , A61B2090/0814 , H04L9/10
摘要： A surgical instrument includes a surgical end effector having a receiving portion for removably receiving therein an interchangeable part. The receiving portion has a communication connection. A handle connected to the end effector actuates the end effector. The handle has a controller electrically connected to the communication connection for authenticating the interchangeable part when placed at the end effector. An interchangeable part is removably connected to the receiving portion and has an encryption device electrically removably connected to the communication connection when placed at the receiving portion. The encryption device authenticates the interchangeable part when queried by the electric controller.
摘要翻译：手术器械包括具有用于可拆卸地在其中容纳可互换部分的接收部分的手术末端执行器。接收部分具有通信连接。连接到末端执行器的手柄致动末端执行器。手柄具有电连接到通信连接的控制器，用于在放置在末端执行器时认证可互换部件。可互换部分可移除地连接到接收部分，并且当放置在接收部分时具有可电连接到通信连接的加密装置。加密装置在由电控制器查询时认证可互换部分。

10. 发明申请

WO2008024638A3 TORQUE-TRANSMITTING, VARIABLY-FLEXIBLE, CORRUGATED INSERTION DEVICE AND METHOD FOR TRANSMITTING TORQUE AND VARIABLY FLEXING A CORRUGATED INSERTION DEVICE 审中-公开
标题翻译：转矩传送，变量柔性，波纹插入装置以及传送转矩和变量转换波纹插入装置的方法
公开(公告)号：WO2008024638A3
公开(公告)日：2008-12-04
申请号：PCT/US2007075701
申请日：2007-08-10
申请人： KMS DEV LLC , SMITH KEVIN , DEVILLE DEREK , KLINE KOREY , PALMER MATHEW
发明人： SMITH KEVIN , DEVILLE DEREK , KLINE KOREY , PALMER MATHEW
IPC分类号： A61F11/00 , A61M37/00
CPC分类号： A61B1/0055
摘要： A torque-transmitting, variably-flexible, corrugated insertion device includes a hollow body having a proximal end with an entrance for receiving an instrument and a distal end with a tip for protrusion of the instrument. A vacuum-activated device transitions the hollow body between a relatively flexible condition and a relatively stiff condition. A corrugated tube transmits torque from the proximal end toward the distal end. A method for transmitting torque and variably flexing an insertion device for receiving an instrument includes providing a hollow body, transmitting torque along the hollow body with a corrugated tube, applying suction to create a vacuum in the hollow body for placing the hollow body in a relatively stiff condition, and relieving the vacuum for placing the hollow body in a relatively flexible condition.
摘要翻译：传递扭矩的可变柔性波纹插入装置包括空心体，该空心体具有带有用于接收器械的入口的近端和带有用于器械的突出的尖端的远端。真空驱动装置将空心体在相对柔韧的状态和相对僵硬的状态之间转换。波纹管将扭矩从近端传递到远端。一种用于传递转矩并可变地弯曲用于接收器械的插入装置的方法包括：提供中空体，沿中空体传递扭矩与波纹管，施加抽吸以在中空体中产生真空，以将中空体置于相对僵硬的状态，并且释放用于使中空体处于相对柔性状态的真空。

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