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1. 发明申请

WO2013101877A2 GENETICALLY MODIFIED PLANTS WITH RESISTANCE TO XANTHOMONAS AND OTHER BACTERIAL PLANT PATHOGENS 审中-公开
标题翻译：遗传修饰植物对西洋参和其他细菌植物病原体的抗性
公开(公告)号：WO2013101877A2
公开(公告)日：2013-07-04
申请号：PCT/US2012/071722
申请日：2012-12-27
申请人： IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. , YANG, Bing , LI, Ting , LIU, Bo
发明人： YANG, Bing , LI, Ting , LIU, Bo
IPC分类号： A01H5/00 , C12N15/82
CPC分类号： C12N15/8281 , C07K14/415 , C12N9/16
摘要： Applicants have successfully generated heritable phenotypes in plants making them resistant to bacterial blight. TAL effector binding elements, (EBEs) of bacterial pathogen disease susceptibility genes are modified to prevent induction of expression associated with disease states caused by the bacterial pathogens. Surprisingly, Applicants have found that modifications may be made in the EBEs of these genes which prevent bacterial pathogen induction, but still allow for normal plant development and seed production. Nucleic acid sequences for generating such plants, amino acid sequences, cells, vectors and expression constructs are included as well as resistant plants, seeds and lines.
摘要翻译：申请人已成功地在植物中产生了遗传表型，使其对细菌性枯萎病具有抗性。细菌病原体易感性基因的TAL效应物结合元件（EBEs）被修饰以防止与由细菌病原体引起的疾病状态相关的表达的诱导。令人惊讶的是，申请人已经发现可以在这些基因的EBE中进行修饰，这些基因预防细菌病原体的诱导，但仍然允许正常的植物发育和种子生产。包括用于产生这种植物，氨基酸序列，细胞，载体和表达构建体的核酸序列以及抗性植物，种子和品系。

2. 发明申请

WO2018209571A1 SMART CHARGING SCHEDULING APPARATUS AND METHOD FOR ELECTRIC VEHICLE 审中-公开
公开(公告)号：WO2018209571A1
公开(公告)日：2018-11-22
申请号：PCT/CN2017/084566
申请日：2017-05-16
申请人： BAYERISCHE MOTOREN WERKE AKTIENGESELLSCHAFT , LIU, Bo
发明人： LIU, Bo , PAGE, Thomas , DING, Qiao , YANG, Qing , HEIN, Christoph Tomoki , GROESBRINK, Stefan
IPC分类号： H02J7/00
摘要： The present disclosure provides a new and improved method and apparatus of scheduling for a charging infrastructure serving a plurality of electric vehicles. In an exemplary embodiment, a computer-implemented method for scheduling a charging infrastructure serving a plurality of electric vehicles is provided, characterized in comprising: making a prediction for a usage pattern of the charging infrastructure with a context based on historical usage patterns of the charging infrastructure and the contexts of the historical usage patterns, and determining a schedule scheme for deciding a distribution of charging spots of the charging infrastructure among the electric vehicles based on the predicted usage pattern.

3. 发明申请

WO2014059597A1 NANOPARTICLE CONTAINING POLYURETHANE DISPERSIONS AFFORDING MATERIALS HAVING IMPROVED TENSILE STRENGTH AND ELONGATION 审中-公开
标题翻译：含有聚氨酯分散剂的纳米颗粒对具有改进的拉伸强度和延伸性的材料
公开(公告)号：WO2014059597A1
公开(公告)日：2014-04-24
申请号：PCT/CN2012/083023
申请日：2012-10-16
申请人： DOW GLOBAL TECHNOLOGIES LLC , GU, Weichao , KANG, Ning , LIU, Bo , YAN, Yunfei , ZHANG, Chao , ZHANG, Hongliang
发明人： GU, Weichao , KANG, Ning , LIU, Bo , YAN, Yunfei , ZHANG, Chao , ZHANG, Hongliang
IPC分类号： C08G18/10 , C08K3/26 , C08K3/00 , C08G18/08 , C08G18/06 , C08G18/12 , C08G18/48 , C08G18/76
CPC分类号： C08G18/283 , C08G18/0866 , C08G18/4841 , C08G18/7671 , C08G2150/90 , C08K3/26 , C08K2003/265 , C08K2201/011 , C09D175/08 , D06N3/0063 , D06N3/14 , D06N3/146 , D06N2205/103 , D06N2211/28 , C08G18/12 , C08G18/3271 , C08L75/04
摘要： Disclosed herein are methods for producing a material from a PUD that contains nanoparticles, wherein said material has improved elongation, tensile strength, and stability, relative to other materials made from PUDs that do not contain nanoparticles, the methods comprising: preparing a polyurethane prepolymer, wherein the prepolymer comprises at least one isocyanate resin, and at least one polyol; preparing a first mixture comprising the polyurethane prepolymer, at least one surfactant, and at least one nanoparticle; preparing a second mixture comprising, the first mixture, water, and a chain extender; and curing the second mixture. PUD based materials and methods of using them are also disclosed herein.
摘要翻译：本文公开了从包含纳米颗粒的PUD制备材料的方法，其中所述材料相对于不含纳米颗粒的PUD制备的其它材料，具有改善的伸长率，拉伸强度和稳定性，所述方法包括：制备聚氨酯预聚物，其中所述预聚物包含至少一种异氰酸酯树脂和至少一种多元醇; 制备包含所述聚氨酯预聚物，至少一种表面活性剂和至少一种纳米颗粒的第一混合物; 制备第二混合物，其包含第一混合物，水和扩链剂; 并固化第二混合物。本文还公开了基于PUD的材料及其使用方法。

4. 发明申请

WO2014059593A1 POLYURETHANE BASED SYNTHETIC LEATHERS COMPRISING NANOPARTICLES AND HAVING IMPROVED PEEL STRENGTH 审中-公开
标题翻译：基于聚氨酯的合成皮革包含纳米颗粒并具有改善的皮肤强度
公开(公告)号：WO2014059593A1
公开(公告)日：2014-04-24
申请号：PCT/CN2012/083016
申请日：2012-10-16
申请人： DOW GLOBAL TECHNOLOGIES LLC , GU, Weichao , KANG, Ning , LIU, Bo , YAN, Yunfei , ZHANG, Chao , ZHANG, Hongliang
发明人： GU, Weichao , KANG, Ning , LIU, Bo , YAN, Yunfei , ZHANG, Chao , ZHANG, Hongliang
IPC分类号： D06N3/14 , D06M15/564
CPC分类号： D06N3/146 , D06N3/0047 , D06N3/0063 , D06N3/14 , D06N2205/103 , D06N2205/20 , D06N2211/28
摘要： Disclosed herein are methods for producing a poromeric synthetic leather having improved peel strength, the method comprising: preparing a polyurethane prepolymer, wherein the prepolymer comprises at least one isocyanate resin, and at least one polyol; preparing a first mixture comprising the polyurethane prepolymer, and at least one surfactant; preparing a second mixture comprising, the first mixture, water, and a chain extender; preparing a third mixture comprising the second mixture, at least one surfactant and a thickening agent, frothing the third mixture and thereby forming a frothed third mixture; applying the frothed third mixture to a fabric that is optionally impregnated with a polyurethane resin and thereby forming a coated fabric; optionally adjusting the thickness of the frothed third mixture on the fabric; and heating the coated fabric sufficiently to dry and cure it; wherein at least one nanoparticle is present in the polyurethane prepolymer, the first mixture, the second mixture, the third mixture, or combinations thereof. Leathers made according to such methods are also disclosed herein.
摘要翻译：本文公开了用于生产具有改善的剥离强度的端基合成革的方法，所述方法包括：制备聚氨酯预聚物，其中所述预聚物包含至少一种异氰酸酯树脂和至少一种多元醇; 制备包含所述聚氨酯预聚物和至少一种表面活性剂的第一混合物; 制备第二混合物，其包含第一混合物，水和扩链剂; 制备包含第二混合物，至少一种表面活性剂和增稠剂的第三混合物，使第三混合物起泡，从而形成发泡的第三混合物; 将发泡的第三混合物施用到任选地用聚氨酯树脂浸渍并由此形成涂布织物的织物; 可选地调节织物上发泡的第三混合物的厚度; 并充分加热涂层织物以使其干燥和固化; 其中至少一种纳米颗粒存在于聚氨酯预聚物中，第一混合物，第二混合物，第三混合物或其组合。根据这种方法制造的皮革也在本文中公开。

5. 发明申请

WO2012177368A1 BIT SCAN CIRCUIT AND METHOD IN NON-VOLATILE MEMORY 审中-公开
标题翻译：非易失性存储器中的位扫描电路和方法
公开(公告)号：WO2012177368A1
公开(公告)日：2012-12-27
申请号：PCT/US2012/040145
申请日：2012-05-31
申请人： SANDISK TECHNOLOGIES INC. , LIU, Bo , PARK, Jongmin , CHEN, Chen , KUO, Tien-Chien
发明人： LIU, Bo , PARK, Jongmin , CHEN, Chen , KUO, Tien-Chien
IPC分类号： G11C29/40 , G11C29/44
CPC分类号： G11C29/40 , G11C29/44
摘要： A circuit (150) for counting in an N-bit string (10) a number of bits M, having a first binary value includes N latch circuits in a daisy chain (100) where each latch circuit has a tag bit that controls each to be either in a no-pass or pass state. Initially the tag bits are set according to the bits of the N-bit string where the first binary value corresponds to a no-pass state. A clock signal having a pulse train is run through the daisy chain to "interrogate" any no-pass latch circuits. It races right through any pass latch circuit. However, for a no-pass latch circuit, a leading pulse while being blocked also resets after a pulse period the tag bit from "no-pass" to "pass" state to allow subsequent pulses to pass. After all no-pass latch circuits have been reset, M is given by the number of missing pulses from the pulse train.
摘要翻译：用于以N位串（10）计数具有第一二进制值的位M的电路（150）包括菊花链（100）中的N个锁存电路，其中每个锁存电路具有一个标签位，要么是没有通过，要么是通过状态。最初，标签位根据N位串的位进行设置，其中第一个二进制值对应于无通状态。具有脉冲串的时钟信号通过菊花链运行以“询问”任何无通路锁存电路。它可以通过任何通过锁存电路进行比赛。然而，对于无通路锁存电路，被阻塞的前导脉冲也在标签位从“无通”状态到“通过”状态的脉冲周期之后复位，以允许随后的脉冲通过。在所有无通路锁存电路复位之后，M由脉冲序列的丢失脉冲数给出。

6. 发明申请

WO2012049491A2 ANALYTE EXTRACTION APPARATUS AND METHOD 审中-公开
标题翻译：分析物萃取装置和方法
公开(公告)号：WO2012049491A2
公开(公告)日：2012-04-19
申请号：PCT/GB2011/051958
申请日：2011-10-11
申请人： SPHERE MEDICAL LIMITED , PETTIGREW, David Michael , LIU, Bo , LAITENBERGER, Peter Georg , BATES, Stephen
发明人： PETTIGREW, David Michael , LIU, Bo , LAITENBERGER, Peter Georg , BATES, Stephen
IPC分类号： G01N30/06
CPC分类号： G01N33/948 , G01N30/06 , G01N30/24 , G01N2030/067 , G01N2030/085 , Y10T436/11 , Y10T436/203332 , Y10T436/255
摘要： Disclosed is an apparatus for automatically extracting i2,6-diisopropylphenol (Propofol), from a complex sample matrix comprising cellular material, e.g. blood, the apparatus comprising a sample reception stage having on output for providing a defined quantity of the complex sample matrix; a mixing stage having a first input in fluidic connection with the output of the sample reception stage, a second input for receiving a lysing agent and an output for providing a mixture of the defined quantity of the complex sample matrix and the lysing agent; a delay stage having an input in fluidic connection with the output of the mixing stage and an output for providing the delayed mixture of the defined quantity of the complex sample matrix and the lysing agent; a filtering stage comprising a sorbent material for mechanically lysing the cellular material, said sorbent material having an affinity for binding Propofol, said filtering stage having an input in fluidic connection with the output of the delay stage; and a controller for controlling the flow rate of the mixture of the defined quantity of the complex sample matrix and the lysing agent through said delay stage. A method for such extraction is also disclosed.
摘要翻译：本发明公开了一种用于从包含细胞材料的复杂样品基质（例如细胞材料）自动提取1,2,6-二异丙基苯酚（丙泊酚）的装置。所述设备包括：样本接收级，其具有用于提供限定量的所述复杂样本矩阵的输出; 混合阶段，其具有与样品接收阶段的输出物流体连接的第一输入端，用于接收裂解剂的第二输入端和用于提供限定量的复杂样品基质和裂解剂的混合物的输出端; 延迟级，其具有与混合级的输出端流体连接的输入端和用于提供限定量的复杂样品基质和裂解剂的延迟混合物的输出端; 包含用于机械裂解所述细胞材料的吸附剂材料的过滤阶段，所述吸附剂材料具有与丙泊酚结合的亲和力，所述过滤阶段具有与所述延迟阶段的输出端流体连接的输入端; 以及控制器，用于通过所述延迟阶段控制限定量的复杂样品基质和裂解剂的混合物的流速。还公开了这种提取的方法。

7. 发明申请

WO2012049486A1 ANALYTE DETECTION METHOD 审中-公开
标题翻译：分析检测方法
公开(公告)号：WO2012049486A1
公开(公告)日：2012-04-19
申请号：PCT/GB2011/051952
申请日：2011-10-11
申请人： SPHERE MEDICAL LIMITED , PETTIGREW, David Michael , LAITENBERGER, Peter Georg , LIU, Bo
发明人： PETTIGREW, David Michael , LAITENBERGER, Peter Georg , LIU, Bo
IPC分类号： G01N33/52 , G01N33/557 , G01N33/94
CPC分类号： G01N33/948 , G01N33/52 , G01N33/557 , Y10T436/14 , Y10T436/203332
摘要： Disclosed is a method of determining the presence of an analyte of interest by means of a detection of a reaction product between the analyte of interest and a reactant, the method comprising extracting the analyte of interest from a complex sample matrix; transferring the analyte of interest to an initial reaction mixture; performing a background measurement on the initial reaction mixture comprising at most a negligible concentration of the reaction product, wherein the reaction conditions present in said initial reaction mixture at least reduce the reaction rate of the formation of the reaction product such that the background measurement can be performed without a measurable change in said negligible concentration; altering the reaction conditions in the initial reaction mixture to accelerate said reaction rate; continuing said reaction until the concentration of the reaction product has stabilized; performing a second measurement on the resultant reaction mixture to obtain a signal correlated to said concentration; and determining the presence of the analyte of interest from a difference between the background measurement and the second measurement. In a preferred embodiment, the analyte of interest is Propofol (2,6-di-isopropylphenol), and the reactant is the activated Gibbs reagent (2,6-dichloroquinoneimine).
摘要翻译：公开了通过检测目标分析物和反应物之间的反应产物来确定感兴趣分析物的存在的方法，该方法包括从复杂样品基质提取目的分析物; 将目标分析物转移到初始反应混合物中; 对起始反应混合物进行背景测量，该反应混合物至少包含反应产物的可忽略的浓度，其中存在于所述初始反应混合物中的反应条件至少降低反应产物形成的反应速率，使得背景测量可以在所述可忽略的浓度中没有可测量的变化; 改变初始反应混合物中的反应条件以加速所述反应速率; 继续反应直到反应产物的浓度稳定; 对所得反应混合物进行第二次测定以获得与所述浓度相关的信号; 以及从背景测量和第二测量之间的差异确定感兴趣分析物的存在。在优选的实施方案中，感兴趣的分析物是异丙酚（2,6-二异丙基苯酚），反应物是活化的吉布斯试剂（2,6-二氯喹啉亚胺）。

8. 发明申请

WO2011040879A1 APPARATUS AND METHOD FOR CERTIFYING A MAGNETIC RECORDING DISK 审中-公开
标题翻译：用于认证磁记录盘的装置和方法
公开(公告)号：WO2011040879A1
公开(公告)日：2011-04-07
申请号：PCT/SG2009/000361
申请日：2009-09-30
申请人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH , LEONG, Siang Huei , NG, Ka Wei , YUAN, Zhimin , LIU, Bo
发明人： LEONG, Siang Huei , NG, Ka Wei , YUAN, Zhimin , LIU, Bo
IPC分类号： G11B7/12
CPC分类号： G01R33/1207
摘要： Apparatuses and methods for certifying a magnetic recording disk (102)are disclosed herein, in a described embodiment, the apparatus (100) comprises a certifier head (104) for testing the disk's magnetic properties and a product head (106) for testing the disk's mechanical properties and the apparatus (100) is configured to enable simultaneous access to the disk (102) by the product head (106) and the certifier head (104). A method of upgrading a media certifier is also disclosed.
摘要翻译：在所描述的实施例中，本文公开了用于认证磁记录盘（102）的装置和方法，所述装置（100）包括用于测试磁盘的磁性的验证头（104）和用于测试磁盘的磁头机械性能和装置（100）被配置为使得能够通过产品头（106）和认证者头（104）同时访问盘（102）。还公开了升级媒体验证者的方法。

9. 发明申请

WO2010065467A8 BRANCHED AND STAR-BRANCHED STYRENE POLYMERS, TELOMERS, AND ADDUCTS, THEIR SYNTHESIS, THEIR BROMINATION, AND THEIR USES 审中-公开
公开(公告)号：WO2010065467A8
公开(公告)日：2010-06-10
申请号：PCT/US2009/066132
申请日：2009-11-30
申请人： ALBEMARLE CORPORATION , LAYMAN, William, J, Jr. , KOLICH, Charles, H. , MACK, Arthur, G. , MCCARNEY, Jonathan, P. , KUMAR, Govindarajulu , WANG, Junzuo , MORICE, Jorge , GE, Zhongxin , LIU, Bo , JOSHI, Ravindra, R. , CHEW, Hoover, B. , LUTHER, Douglas, W. , WHITE, Kimberly, M.
发明人： LAYMAN, William, J, Jr. , KOLICH, Charles, H. , MACK, Arthur, G. , MCCARNEY, Jonathan, P. , KUMAR, Govindarajulu , WANG, Junzuo , MORICE, Jorge , GE, Zhongxin , LIU, Bo , JOSHI, Ravindra, R. , CHEW, Hoover, B. , LUTHER, Douglas, W. , WHITE, Kimberly, M.
IPC分类号： C08F112/08 , C08F2/38 , C08F4/48 , C08F8/20 , C08K5/00 , C08L51/04 , C08L55/02 , C08L23/00 , C08L61/06 , C08L67/00 , C08L77/00 , C08L75/00
摘要： New branched or star-branched styrene polymeric, telomeric, and monomeric product distributions, their preparation, their use as raw materials for bromination to produce flame retardants, the flame retardants themselves, and their use as flame retardants in various polymeric substrates are described.

10. 发明申请

WO2010019547A1 IMINE DERIVATIVES AS CANNABINOID RECEPTOR LIGANDS 审中-公开
标题翻译：作为CANNABINOID受体配体的衍生物
公开(公告)号：WO2010019547A1
公开(公告)日：2010-02-18
申请号：PCT/US2009/053369
申请日：2009-08-11
申请人： ABBOTT LABORATORIES , CARROLL, William, A. , DART, Michael, J. , FROST, Jennifer, M. , KOLASA, Teodozyj , LATSHAW, Steven, P. , LIU, Bo , PATEL, Meena, V. , PEREZ-MEDRANO, Arturo , WANG, Xueqing
发明人： CARROLL, William, A. , DART, Michael, J. , FROST, Jennifer, M. , KOLASA, Teodozyj , LATSHAW, Steven, P. , LIU, Bo , PATEL, Meena, V. , PEREZ-MEDRANO, Arturo , WANG, Xueqing
IPC分类号： C07D261/14 , C07D407/06 , C07D417/06 , C07D285/135 , A61K31/433 , A61P29/00
CPC分类号： C07D261/14 , C07D285/135 , C07D407/06 , C07D417/06
摘要： Disclosed herein are cannabinoid receptor ligands of formula (I), wherein Y, X 1 , X 2 , X 3 , R 1 , and R 2 are as defined in the specification. Compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions are also disclosed.
摘要翻译：本文公开了式（I）的大麻素受体配体，其中Y，X1，X2，X3，R1和R2如说明书中所定义。还公开了包含这些化合物的组合物，以及使用这些化合物和组合物治疗病症和障碍的方法。

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