专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2007028169A2 A METHOD FOR CELL IMPLANTATION 审中-公开
标题翻译：一种细胞植入方法
公开(公告)号：WO2007028169A2
公开(公告)日：2007-03-08
申请号：PCT/US2006/034673
申请日：2006-09-05
申请人： INTERFACE BIOTECH A/S , EVERLAND, Hanne , CLAUSEN, Christian , OSTHER, Kurt
发明人： EVERLAND, Hanne , CLAUSEN, Christian , OSTHER, Kurt
IPC分类号： A61K35/12
CPC分类号： A61K38/4833 , A61K35/32 , A61K38/363 , A61L27/3843 , A61K2300/00
摘要： The present invention provides for a method for tissue engineering by cell implantation that involves the use of a scaffold in situ at the site of a defect, where the therapeutic cells are fixed in place into the scaffold only once the scaffold is inserted at the site of the tissue defect, thereby locking not only the cells to the scaffold, but also the scaffold to the tissue defect. The invention also provides a kit of parts suitable for performing the method of the invention.
摘要翻译：本发明提供了一种通过细胞移植进行组织工程的方法，该方法涉及在缺损部位的原位使用支架，其中一旦将支架插入到位于组织缺陷，从而不仅将细胞锁定到支架，而且将支架锁定到组织缺损。本发明还提供适用于执行本发明方法的一组零件。

2. 发明申请

WO2002061052A3 AN IMPROVED IN VITRO METHOD OF CULTURING MAMMALIAN CELLS FOR AUTOLOGOUS CELL IMPLANTATION/TRANSPLANTATION METHODS 审中-公开
公开(公告)号：WO2002061052A3
公开(公告)日：2002-08-08
申请号：PCT/DK2002/000065
申请日：2002-01-29
申请人： INTERFACE BIOTECH A/S , STORGAARD, Peter , OSTHER, Kurt
发明人： STORGAARD, Peter , OSTHER, Kurt
IPC分类号： C12N5/00
摘要： A production method for producing cell colony forming units in vitro from a mammalian tissue explant, the method comprises the steps of a) growing a piece of the mammalian tissue explant in a growth medium to obtain cell colony forming units from immature cells from the piece of explant, and b) harvesting cells from one or more of the cell colony forming units for use in Autologous Cell Implantation/transplantation methods. The mammalian tissue explant is selected from the group consisting of cartilage; bone such as, e.g., bone marrow; connective tissue; muscle tissue such as, e.g., smooth muscle tissue, heart tissue, liver tissue and skeletal muscle tissue; skin tissue such as, e.g., periosteum; mucosal tissue; brain tissue, pancreas tissue and blood vessels. In particularly, the mammalian tissue explant is cartilage, such as elastic, fibro, hyalin or articular hyalin cartilage. The cells obtained are suitable for use in autologous implantation/transplantation methods. In a specific embodiment, the cell obtained are chondroytes, especially for use in autologous chondrocyte implantation (ACI) methods.

3. 发明申请

WO2004110512A3 A METHOD FOR CELL IMPLANTATION 审中-公开
公开(公告)号：WO2004110512A3
公开(公告)日：2004-12-23
申请号：PCT/DK2004/000408
申请日：2004-06-11
申请人： INTERFACE BIOTECH A/S , OSTHER, Kurt
发明人： OSTHER, Kurt
IPC分类号： A61L27/38
摘要： An endoscopic method for treating cartilage or bone defects in an animal, said method comprising the steps of: I) identifying the position of the defect, ii) applying cells selected from the group consisting of chondrocytes, chondroblasts, osteocytes and osteoblasts and combinations thereof into the cartilage or bone defect. In particular, the invention relates to a method for arthroscopic or endoscopic implantation of homologous or autologous cells into a defect of an animal body, the method comprising a step of I) arthroscopic or endoscopic application of a fluid to a cavity or surface containing the defect, and the steps of ii) application of the cells to the defect substantially simultaneously with a support material, the application being performed at the defect covered by the fluid, iii) mixing of the cells and the supporting material, iv) solidification of the supporting material so that the defect is covered by a mixture of cells and support material without any significant amount of fluid, and v) optionally, removal of the fluid from the cavity or surface by drainage or suction.

4. 发明申请

WO2002061052A2 AN IMPROVED IN VITRO METHOD OF CULTURING MAMMALIAN CELLS FOR AUTOLOGOUS CELL IMPLANTATION/TRANSPLANTATION METHODS 审中-公开
标题翻译：改进用于自体细胞植入/移植方法的培养MAMMALIAN细胞的体外培养方法
公开(公告)号：WO2002061052A2
公开(公告)日：2002-08-08
申请号：PCT/DK2002/000065
申请日：2002-01-29
申请人： INTERFACE BIOTECH A/S , STORGAARD, Peter , OSTHER, Kurt
发明人： STORGAARD, Peter , OSTHER, Kurt
IPC分类号： C12N5/00
CPC分类号： C12N5/0655 , C12N5/0668 , C12N2500/60 , C12N2509/00 , C12N2523/00
摘要： A production method for producing cell colony forming units in vitro from a mammalian tissue explant, the method comprises the steps of a) growing a piece of the mammalian tissue explant in a growth medium to obtain cell colony forming units from immature cells from the piece of explant, and b) harvesting cells from one or more of the cell colony forming units for use in Autologous Cell Implantation/transplantation methods. The mammalian tissue explant is selected from the group consisting of cartilage; bone such as, e.g., bone marrow; connective tissue; muscle tissue such as, e.g., smooth muscle tissue, heart tissue, liver tissue and skeletal muscle tissue; skin tissue such as, e.g., periosteum; mucosal tissue; brain tissue, pancreas tissue and blood vessels. In particularly, the mammalian tissue explant is cartilage, such as elastic, fibro, hyalin or articular hyalin cartilage. The cells obtained are suitable for use in autologous implantation/transplantation methods. In a specific embodiment, the cell obtained are chondroytes, especially for use in autologous chondrocyte implantation (ACI) methods.
摘要翻译：一种用于从哺乳动物组织外植体体外产生细胞集落形成单元的生产方法，所述方法包括以下步骤：a）在生长培养基中培养一片哺乳动物组织外植体以获得细胞集落形成单位来自所述外植体的未成熟细胞，以及b）从用于自体细胞植入/移植方法的一个或多个细胞集落形成单位收获细胞。哺乳动物组织外植体选自软骨; 骨，例如骨髓; 结缔组织; 肌肉组织，例如平滑肌组织，心脏组织，肝组织和骨骼肌组织; 皮肤组织，例如骨膜; 粘膜组织; 脑组织，胰腺组织和血管。特别地，哺乳动物组织外植体是软骨，例如弹性，纤维，透明质或关节透明质软骨。获得的细胞适合用于自体植入/移植方法。在具体实施方案中，所获得的细胞是软骨细胞，特别是用于自体软骨细胞植入（ACI）方法。

5. 发明申请

WO2013007266A1 WOUND DRESSING WITH THROMBIN 审中-公开
标题翻译：带THROMBIN的连接线
公开(公告)号：WO2013007266A1
公开(公告)日：2013-01-17
申请号：PCT/DK2012/050264
申请日：2012-07-10
申请人： COLOPLAST A/S , EVERLAND, Hanne , OSTHER, Kurt , VANGE, Jakob , NIELSEN, Lene Feldskov
发明人： EVERLAND, Hanne , OSTHER, Kurt , VANGE, Jakob , NIELSEN, Lene Feldskov
IPC分类号： A61L15/26 , A61L15/38
CPC分类号： A61F13/00991 , A61L15/26 , A61L15/32 , A61L15/38 , A61L15/425 , A61L2400/04 , C08L75/04
摘要： The present invention relates to method of preparing an absorbent wound care device comprising an active agent on a wound contacting surface, such as e.g. a protein or an enzyme, by the use of electrospraying, and a wound care device obtained by said method. The invention further relates to a wound care device comprising Thrombin and a polyurethane foam, and a method of treating bleeding.
摘要翻译：本发明涉及一种制备吸收性伤口护理装置的方法，其包括在伤口接触表面上的活性剂，蛋白质或酶，通过使用电喷雾，以及通过所述方法获得的伤口护理装置。本发明还涉及包含凝血酶和聚氨酯泡沫的伤口护理装置以及治疗渗血的方法。

6. 发明申请

WO2007036232A1 METHODS FOR DIFFERENTIATING STEM CELLS AND USE THEREOF IN THE TREATMENT OF DENTAL CONDITIONS 审中-公开
标题翻译：用于分化干细胞的方法及其在治疗牙齿病症中的应用
公开(公告)号：WO2007036232A1
公开(公告)日：2007-04-05
申请号：PCT/DK2006/000533
申请日：2006-09-28
申请人： COPYGENE A/S , OSTHER, Kurt , CLAUSEN, Christian , PEDERSEN, Klaus Riskær
发明人： OSTHER, Kurt , CLAUSEN, Christian , PEDERSEN, Klaus Riskær
IPC分类号： C12N5/06 , A61K6/00
CPC分类号： C12N5/0654 , A61K35/12 , C12N5/0664
摘要： The present invention relates to a method for propagating and/or differentiating mammalian cells, the method comprising exposing or co-culturing mammalian cells with one or more of periodontal ligament tissue, periodontal ligament proteins or factors derived from periodontal ligament tissue, to obtain cells having PDL characteristics and fulfilling at least one of the following: i) show periodontal characteristics as evidenced with Von Kossa method in which calcium phosphate deposits are stained brown to black, ii) show increased osteopontin and osteocalcin and at the same time decreased bone sialoprotein (bone sialoprotein Il or BSP), iii) are capable of being implanted to repair and/or regenerate periodontal tissue, iv) are capable of repairing disorders such as paradentitis also called paradentosis, or periodontitis by healing of the gum line towards the teeth, and v) are accepted by the host without significant immune reaction or cell rejection.
摘要翻译：本发明涉及一种用于繁殖和/或分化哺乳动物细胞的方法，所述方法包括将一种或多种牙周韧带组织，牙周韧带蛋白或源自牙周韧带组织的因子暴露或共培养哺乳动物细胞，以获得具有 PDL特征并满足以下至少一个：i）显示了Von Kossa方法证明的牙周特征，其中磷酸钙沉积物被染成棕色至黑色，ii）显示出增加的骨桥蛋白和骨钙素，同时降低骨涎蛋白（骨骼）唾液酸蛋白II或BSP），iii）能够被植入以修复和/或再生牙周组织，iv）能够通过牙龈愈合牙齿修复诸如也称为间盘突出症的症状或牙周病，v ）被宿主接受，没有显着的免疫反应或细胞排斥。

7. 发明申请

WO2012136587A1 REPAIR OF NEURODEGENERATIVE DISEASE 审中-公开
标题翻译：修复神经病变疾病
公开(公告)号：WO2012136587A1
公开(公告)日：2012-10-11
申请号：PCT/EP2012/055816
申请日：2012-03-30
申请人： HumaCell Inc. , OSTHER, Kurt , KOEFOED, Peter
发明人： OSTHER, Kurt
IPC分类号： A61K38/17 , A61P25/28
CPC分类号： A61K35/51 , A61K35/14 , A61K35/28 , A61K35/35 , A61K35/50 , A61K38/1709 , A61K38/44 , A61K48/00 , C12Y114/99003 , A61K2300/00
摘要： Disclosed are methods and means for treatment of neurodegenerative disease. In particular, the methods entail administration of stem cells expressing genes encoding therapeutically effective amounts of Nrf2. Also disclosed is a gene-therapy method for treatment of neurodegenerative disease, where genes encoding Nrf2 are administered.
摘要翻译：公开了治疗神经变性疾病的方法和手段。特别地，该方法需要施用表达编码治疗有效量的Nrf2的基因的干细胞。还公开了治疗神经变性疾病的基因治疗方法，其中施用编码Nrf2的基因。

8. 发明申请

WO2010119036A1 NOVEL POST-TRANSLATIONAL FIBRINOGEN VARIANTS 审中-公开
标题翻译：新型翻译后的纤维蛋白变体
公开(公告)号：WO2010119036A1
公开(公告)日：2010-10-21
申请号：PCT/EP2010/054834
申请日：2010-04-13
申请人： HUMAGENE INC. , OSTHER, Kurt
发明人： OSTHER, Kurt
IPC分类号： A61K38/48 , A61K31/405 , C07K14/745 , A61K35/16 , A61K38/36
CPC分类号： C07K14/75 , A61K38/00
摘要： Provided are novel post-translationally modified variants of fibrinogen, in particular human fibrinogen, a method for producing and isolating said variants, as well as methods of using the variant, in particular in systemic and local/topical treatment and prophylaxis of excessive bleeding.
摘要翻译：提供了纤维蛋白原，特别是人纤维蛋白原的新的翻译后修饰变体，用于产生和分离所述变体的方法，以及使用该变体的方法，特别是全身和局部/局部治疗和预防过度出血。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式