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1. 发明申请

WO2006063205A3 HIGH THROUGHPUT SCREENING OF CATALYSTS USING SPIN RESONANCE 审中-公开
标题翻译：使用旋转共振的催化剂的高通量筛选
公开(公告)号：WO2006063205A3
公开(公告)日：2007-02-22
申请号：PCT/US2005044562
申请日：2005-12-08
申请人： INTEMATIX CORP , XIANG XIAO-DONG , YANG HAITAO , WANG GANG , MELMAN JONATHAN
发明人： XIANG XIAO-DONG , YANG HAITAO , WANG GANG , MELMAN JONATHAN
IPC分类号： G01V3/00 , G05F1/00
CPC分类号： G01N33/542 , G01N24/087 , G01N24/088 , G01N2500/00 , G01R33/323 , G01R33/34 , G01R33/34053 , G01R33/3456 , G01R33/44 , G01R33/46 , G01R33/48 , G01R33/60 , G06F19/16
摘要： High throughput screening of catalyst libraries may be performed using spin resonance techniques, and an evanescent wave probe developed by the present inventors. The probe may operate using either nuclear magnetic resonance or electron spin resonance techniques. In one configuration, a scanning evanescent wave spin resonance probe is used in conjunction with a library of catalysts or other materials, and localized detection of spin resonance is carried out at each library address. In another configuration, the evanescent wave probe is used in a micro-reactor array assay.
摘要翻译：可以使用自旋共振技术和由本发明人开发的ev逝波探针来进行催化剂文库的高通量筛选。探针可以使用核磁共振或电子自旋共振技术进行操作。在一种配置中，扫描ev逝波自旋共振探针与催化剂或其他材料的文库结合使用，并且在每个文库地址进行自旋共振的局部检测。在另一种配置中，ev逝波探针用于微反应器阵列测定。

2. 发明申请

WO2007061843A2 REMOTELY RF POWERED COMFORMABLE THERMAL APPLICATORS 审中-公开
标题翻译：远程射频功率可控热应用
公开(公告)号：WO2007061843A2
公开(公告)日：2007-05-31
申请号：PCT/US2006044672
申请日：2006-11-17
申请人： INTEMATIX CORP , XIANG XIAO-DONG , WANG GANG , YANG HAITAO , MELMAN JONATHAN , DIONNE GERALD FRANCIS
发明人： XIANG XIAO-DONG , WANG GANG , YANG HAITAO , MELMAN JONATHAN , DIONNE GERALD FRANCIS
IPC分类号： A61F2/00
CPC分类号： A61N1/406 , A61K41/0052 , A61K49/1818
摘要： The present embodiments are directed to cancer therapy; specifically a technique called "nanoparticle ferromagnetic resonance heating," where ferromagnetic resonance heating in addition to an RF hyperthermia treatment is used to cause cancer cell apoptosis and necrosis. An apparatus for carrying out a ferromagnetic resonance heating treatment of a tumor, comprises a volume concentration of super paramagnetic particles contained within the interior of the tumor, the concentration ranging from about 0.1 to about 1 percent; a magnetic field source configured to deliver a gradient DC magnetic field to the region of the tumor; and an energy source configured to deliver to the tumor an RF field at a frequency ranging from about 100 to 200 MHz. The apparatus of claim 1, wherein the super paramagnetic particles are selected from the group consisting of maghemite (?-Fe 2 O 3 ) based compounds, and yttrium iron garnet (Y 3 Fe 5 O 12 ) based compounds.
摘要翻译：本实施例涉及癌症治疗; 具体地，称为“纳米颗粒铁磁共振加热”的技术，其中除了RF热疗处理之外的铁磁共振加热被用于引起癌细胞凋亡和坏死。用于进行肿瘤的铁磁共振加热处理的装置包括肿瘤内部所含的超顺磁性颗粒的体积浓度，其浓度范围为约0.1％至约1％; 磁场源，被配置为向所述肿瘤的区域递送梯度DC磁场; 以及能量源，其被配置为以大约100至200MHz的频率向所述肿瘤输送RF场。 2.根据权利要求1所述的装置，其中所述超顺磁性粒子选自由以下物质组成的组：由磁赤铁矿（α-Fe 2 O 3 O 3）基化合物和钇铁石榴石（Y 3 5 12 12）基的化合物。

3. 发明申请

WO2008057138A3 SCREENING OF COMBINATORIAL LIBRARIES USING RADIOACTIVITY 审中-公开
标题翻译：组合文库的放射性筛选
公开(公告)号：WO2008057138A3
公开(公告)日：2008-11-06
申请号：PCT/US2007008320
申请日：2007-04-04
申请人： INTEMATIX CORP , XIANG XIAO-DONG , MELMAN JONATHAN , WANG GANG
发明人： XIANG XIAO-DONG , MELMAN JONATHAN , WANG GANG
IPC分类号： C09K11/54 , C09K11/77
CPC分类号： C40B40/00 , G01N33/60
摘要： The combinatorial approach to materials synthesis can create vast libraries of materials. Some luminescent materials can be activated by the application of electrical current. Additionally, these materials can be activated by the application of an electron gun or some other electron source, such as a /3-emitter. In its simplest form, a library of materials can be screened for luminescence by placing the library in a position to collect beta particles emitted from radioactive /3-emitters.
摘要翻译：材料合成的组合方法可以创建大量的材料库。一些发光材料可以通过施加电流来激活。此外，这些材料可以通过应用电子枪或其他电子源（如三分之一发射器）来激活。以其最简单的形式，可以通过将文库放置在收集放射性/ 3-发射体发射的β粒子的位置来筛选材料库中的发光。

4. 发明申请

WO2007126725A3 SYSTEMS AND METHODS OF COMBINATORIAL SYNTHESIS 审中-公开
标题翻译：组合合成的系统和方法
公开(公告)号：WO2007126725A3
公开(公告)日：2008-04-24
申请号：PCT/US2007007358
申请日：2007-03-23
申请人： INTEMATIX CORP , XIANG XIAO-DONG , WANG GANG , SHAN WEI , MELMAN JONATHAN
发明人： XIANG XIAO-DONG , WANG GANG , SHAN WEI , MELMAN JONATHAN
IPC分类号： G01N33/00
CPC分类号： G01N21/1717
摘要： Disclosed are methods to synthesize new functional materials in an effective and efficient way. These methods include physical vapor deposition and laser-assisted epitaxial growth capable of synthesizing materials comprising a plurality of precursors with similar or dissimilar chemical and/or physical properties. The designated materials are formed during the combinatorial synthesis without the neccessity of post-deposition furnace heating to thermally activate simultaneous reaction and diffusion of precursor multilayers. Modulated photoreflectance spectroscopy may be used to screen regions of the library to assess deposition conditions.
摘要翻译：公开了以有效和高效的方式合成新功能材料的方法。这些方法包括物理气相沉积和激光辅助外延生长，其能够合成包含具有相似或不同化学和/或物理性质的多种前体的材料。指定的材料在组合合成期间形成，而不需要后沉积炉加热，以热激活前体多层的同时反应和扩散。可以使用调制光反射光谱来筛选文库的区域以评估沉积条件。

5. 发明申请

WO2007061843A8 REMOTELY RF POWERED COMFORMABLE THERMAL APPLICATORS 审中-公开
公开(公告)号：WO2007061843A8
公开(公告)日：2007-08-16
申请号：PCT/US2006044672
申请日：2006-11-17
申请人： INTEMATIX CORP , XIANG XIAO-DONG , WANG GANG , YANG HAITAO , MELMAN JONATHAN , DIONNE GERALD FRANCIS
发明人： XIANG XIAO-DONG , WANG GANG , YANG HAITAO , MELMAN JONATHAN , DIONNE GERALD FRANCIS
IPC分类号： A61F2/00
CPC分类号： A61N1/406 , A61K41/0052 , A61K49/1818
摘要： The present embodiments are directed to cancer therapy; specifically a technique called "nanoparticle ferromagnetic resonance heating," where ferromagnetic resonance heating in addition to an RF hyperthermia treatment is used to cause cancer cell apoptosis and necrosis. An apparatus for carrying out a ferromagnetic resonance heating treatment of a tumor, comprises a volume concentration of super paramagnetic particles contained within the interior of the tumor, the concentration ranging from about 0.1 to about 1 percent; a magnetic field source configured to deliver a gradient DC magnetic field to the region of the tumor; and an energy source configured to deliver to the tumor an RF field at a frequency ranging from about 100 to 200 MHz. The apparatus of claim 1, wherein the super paramagnetic particles are selected from the group consisting of maghemite (?-Fe 2 O 3 ) based compounds, and yttrium iron garnet (Y 3 Fe 5 O 12 ) based compounds.

6. 发明申请

WO2007098109A3 HYDROGEN-GENERATING SOLID FUEL CARTRIDGE 审中-公开
标题翻译：氢气发生固体燃料箱
公开(公告)号：WO2007098109A3
公开(公告)日：2008-11-20
申请号：PCT/US2007004276
申请日：2007-02-16
申请人： INTEMATIX CORP , ZHU GUANGHUI , XIANG XIAO-DONG , MELMAN JONATHAN
发明人： ZHU GUANGHUI , XIANG XIAO-DONG , MELMAN JONATHAN
IPC分类号： H01M8/18
CPC分类号： C01B3/065 , C01B3/501 , C01B2203/02 , C01B2203/041 , C01B2203/0495 , C01B2203/1041 , C01B2203/1047 , C01B2203/1052 , C01B2203/1058 , C01B2203/1076 , C01B2203/1205 , H01M8/04208 , H01M8/04216 , H01M8/04291 , H01M8/065 , H01M2008/1095 , H01M2250/30 , Y02B90/18 , Y02E60/362
摘要： Disclosed herein is a novel hydrogen-generating, solid fuel cartridge which may be used to provide hydrogen to a protein exchange membrane (PEM) fuel cell. The cartridge contains a mixture of the hydrogen-generating solid fuel and a catalyst. The solid fuel/catalyst mixture has a packing fraction greater than about 55 percent. Throughout the fuel/catalyst mixture is means for distributing the liquid reactant; there is also a network of hydrogen-collecting, gas permeable membranes for removing the hydrogen product from the cartridge. The hydrogen-generating solid fuel cartridge may further include a liquid reactant distribution plate for distributing the liquid reactant to the solid fuel/catalyst mixture in a substantially uniform manner. The distribution plate has distribution channels arranged in a fractal pattern.
摘要翻译：本文公开了一种新颖的产氢固体燃料盒，其可用于向蛋白质交换膜（PEM）燃料电池提供氢。筒包含产生氢的固体燃料和催化剂的混合物。固体燃料/催化剂混合物的填充率大于约55％。整个燃料/催化剂混合物是用于分配液体反应物的装置; 还有一个用于从盒中除去氢产物的氢气收集透气膜网络。产氢固体燃料盒还可以包括液体反应物分配板，用于以基本均匀的方式将液体反应物分配到固体燃料/催化剂混合物。分布板具有以分形图案布置的分配通道。

7. 发明申请

WO2012075391A3 SOLID-STATE LIGHT EMITTING DEVICES AND SIGNAGE WITH PHOTOLUMINESCENCE WAVELENGTH CONVERSION AND PHOTOLUMINESCENT COMPOSITIONS THEREFOR 审中-公开
标题翻译：固态光发射器件和具有光致变化波长转换和光致发光器件的信号
公开(公告)号：WO2012075391A3
公开(公告)日：2012-11-22
申请号：PCT/US2011063057
申请日：2011-12-02
申请人： INTEMATIX CORP , YUAN XIANGLONG , DAI BING , MELMAN JONATHAN , EDWARDS CHARLES
发明人： YUAN XIANGLONG , DAI BING , MELMAN JONATHAN , EDWARDS CHARLES
IPC分类号： H01L33/50 , F21V7/00
CPC分类号： H01L33/502 , B41F15/00 , C09K11/02 , C09K11/7734 , C09K11/7774 , G02B6/005 , G02F1/133615 , G02F2001/133614 , H01L33/501 , H01L33/60 , H01L2933/0041 , H01L2933/0058
摘要： A photoluminescent composition ("phosphor ink") comprises a suspension of particles of at least one blue light (380nm to 480nm) excitable phosphor material in a light transmissive liquid binder in which the weight loading of at least one phosphor material to binder material is in a range 40% to 75%. The binder can be U.V. curable, thermally curable, solvent based or a combination thereof and comprise a polymer resin; a monomer resin, an acrylic, a silicone or a fluorinated polymer. The composition can further comprise particles of a light reflective material suspended in the liquid binder. Photoluminescence wavelength conversion components; solid-state light emitting devices; light emitting signage surfaces and light emitting signage utilizing the composition are disclosed.
摘要翻译：光致发光组合物（“荧光体油墨”）包括在透光性液体粘合剂中的至少一种蓝光（380nm至480nm）可激发荧光体材料的颗粒悬浮液，其中至少一种磷光体材料对粘合剂材料的重量负载在范围在40％至75％之间。粘合剂可以是U.V. 可固化，可热固化，溶剂基或其组合，并且包含聚合物树脂; 单体树脂，丙烯酸，硅氧烷或氟化聚合物。组合物还可以包含悬浮在液体粘合剂中的光反射材料的颗粒。光致发光波长转换元件; 固态发光器件; 公开了发光标牌表面和利用该组合物的发光标牌。

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