基本信息:
- 专利标题： REMOTELY RF POWERED COMFORMABLE THERMAL APPLICATORS
- 专利标题（中）：远程射频功率可控热应用
- 申请号：PCT/US2006044672 申请日：2006-11-17
- 公开(公告)号：WO2007061843A2 公开(公告)日：2007-05-31
- 发明人： XIANG XIAO-DONG , WANG GANG , YANG HAITAO , MELMAN JONATHAN , DIONNE GERALD FRANCIS
- 申请人： INTEMATIX CORP , XIANG XIAO-DONG , WANG GANG , YANG HAITAO , MELMAN JONATHAN , DIONNE GERALD FRANCIS
- 专利权人： INTEMATIX CORP,XIANG XIAO-DONG,WANG GANG,YANG HAITAO,MELMAN JONATHAN,DIONNE GERALD FRANCIS
- 当前专利权人： INTEMATIX CORP,XIANG XIAO-DONG,WANG GANG,YANG HAITAO,MELMAN JONATHAN,DIONNE GERALD FRANCIS
- 优先权： US73798705 2005-11-17; US60108306 2006-11-16
- 主分类号： A61F2/00
- IPC分类号： A61F2/00
摘要：
The present embodiments are directed to cancer therapy; specifically a technique called "nanoparticle ferromagnetic resonance heating," where ferromagnetic resonance heating in addition to an RF hyperthermia treatment is used to cause cancer cell apoptosis and necrosis. An apparatus for carrying out a ferromagnetic resonance heating treatment of a tumor, comprises a volume concentration of super paramagnetic particles contained within the interior of the tumor, the concentration ranging from about 0.1 to about 1 percent; a magnetic field source configured to deliver a gradient DC magnetic field to the region of the tumor; and an energy source configured to deliver to the tumor an RF field at a frequency ranging from about 100 to 200 MHz. The apparatus of claim 1, wherein the super paramagnetic particles are selected from the group consisting of maghemite (?-Fe 2 O 3 ) based compounds, and yttrium iron garnet (Y 3 Fe 5 O 12 ) based compounds.
摘要（中）：
本实施例涉及癌症治疗; 具体地，称为“纳米颗粒铁磁共振加热”的技术，其中除了RF热疗处理之外的铁磁共振加热被用于引起癌细胞凋亡和坏死。 用于进行肿瘤的铁磁共振加热处理的装置包括肿瘤内部所含的超顺磁性颗粒的体积浓度，其浓度范围为约0.1％至约1％; 磁场源，被配置为向所述肿瘤的区域递送梯度DC磁场; 以及能量源，其被配置为以大约100至200MHz的频率向所述肿瘤输送RF场。 2.根据权利要求1所述的装置，其中所述超顺磁性粒子选自由以下物质组成的组：由磁赤铁矿（α-Fe 2 O 3 O 3）基化合物和钇铁石榴石（Y 3 5 12 12）基的化合物。
公开/授权文献:
- WO2007061843A8 REMOTELY RF POWERED COMFORMABLE THERMAL APPLICATORS 公开/授权日：2007-08-16