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1. 发明申请

WO9530018A3 RECOMBINANT POXVIRUSES WITH FOREIGN POLYNUCLEOTIDES IN ESSENTIAL REGIONS 审中-公开
标题翻译：具有特殊区域的外来多核苷酸的重组病毒
公开(公告)号：WO9530018A3
公开(公告)日：1996-01-04
申请号：PCT/EP9501629
申请日：1995-04-28
申请人： IMMUNO AG , FALKNER FALKO GUENTER , HOLZER GEORG , DORNER FRIEDRICH
发明人： FALKNER FALKO-GUENTER , HOLZER GEORG , DORNER FRIEDRICH
IPC分类号： A01K67/027 , A61K39/00 , C07K14/07 , C07K14/16 , C12N5/10 , C12N7/00 , C12N7/01 , C12N15/09 , C12N15/39 , C12N15/863 , C12R1/92 , C12N15/86 , A01K67/00 , C12N15/16 , C12N15/63
CPC分类号： C12N15/86 , A01K2217/05 , A61K39/00 , C07K14/005 , C12N2710/24122 , C12N2710/24143 , C12N2740/16222 , C12N2830/00 , C12N2830/002 , C12N2830/15 , C12N2830/42 , C12N2830/55 , C12N2830/60 , C12N2840/203
摘要： Defective poxviruses that lack a function imparted by an essential region of its parental poxvirus can be employed for protein production and vaccination, among other uses. A polynucleotide encoding the protein to be produced by the recombinant virus is inserted into the defective poxvirus and placed under transcriptional control of a promoter. The defective poxvirus is viable when the lost function of the essential region is complemented by a host cell, transgenic animal or helper virus.

2. 发明申请

WO9615231A3 METHOD FOR PRODUCING BIOLOGICALS IN PROTEIN-FREE CMETHOD FOR PRODUCING BIOLOGICALS IN PROTEIN-FREE CULTURE ULTURE 审中-公开
标题翻译：在无蛋白培养基中生产生物学的无蛋白质生物学方法
公开(公告)号：WO9615231A3
公开(公告)日：1996-08-01
申请号：PCT/EP9504439
申请日：1995-11-10
申请人： IMMUNO AG , KISTNER OTFRIED , BARRETT NOEL , MUNDT WOLFGANG , DORNER FRIEDRICH
发明人： KISTNER OTFRIED , BARRETT NOEL , MUNDT WOLFGANG , DORNER FRIEDRICH
IPC分类号： G01N33/531 , A61K39/00 , A61K39/12 , A61K39/145 , A61K39/15 , A61K39/245 , C07K14/11 , C12N7/00 , C12N7/02 , C12P21/00 , G01N33/569 , C12N5/00
CPC分类号： C07K14/005 , A61K39/00 , A61K39/12 , A61K39/145 , A61K39/245 , A61K2039/5252 , A61K2039/55505 , C12N7/00 , C12N2500/95 , C12N2710/16634 , C12N2710/16651 , C12N2710/24151 , C12N2720/12351 , C12N2760/16122 , C12N2760/16134 , C12N2760/16151 , C12N2760/16234 , C12N2770/24151
摘要： The present invention refers to a method for producing viruses, selected from the group of flaviviridae, poxviridae and reoviridae and vaccines derived therefrom as well as to cells cultured under protein-free conditions. These cells show improved capabilities for propagating viruses, and eliminate the need for costly and time-consuming viral passaging und purification.
摘要翻译：本发明涉及一种选自黄病毒科，痘病毒科和呼肠肠病毒病毒的病毒及其衍生的疫苗以及在无蛋白质条件下培养的细胞的方法。这些细胞显示出增强的病毒传播能力，并且消除了昂贵且耗时的病毒传代和纯化的需要。

3. 发明申请

WO9425596A3 IMMUNOGENIC FORMULATION OF OSPC ANTIGEN VACCINES FOR THE PREVENTION AND TREATMENT OF LYME DISEASE AND RECOMBINANT METHODS FOR THE PREPARATION OF SUCH ANTIGENS 审中-公开
标题翻译：用于预防和治疗LYME疾病的OSPC抗原疫苗的免疫组织化学和用于制备这种抗原的重组方法
公开(公告)号：WO9425596A3
公开(公告)日：1994-12-22
申请号：PCT/EP9401365
申请日：1994-04-29
申请人： IMMUNO AG , LIVEY IAN , CROWE BRIAN , DORNER FRIEDRICH
发明人： LIVEY IAN , CROWE BRIAN , DORNER FRIEDRICH
IPC分类号： C12N15/09 , A61K39/00 , A61K39/02 , A61P31/04 , C07K14/20 , C12N1/19 , C12N1/21 , C12N15/31 , C12P21/02 , C12R1/01 , C12R1/19 , C12R1/84 , C12R1/89 , C07K13/00 , C12N15/10 , C12N15/70 , C12N15/74
CPC分类号： C07K14/20 , A61K39/00
摘要： An approach to Borrelia vaccine formulation taking into account serological, genotypic and epidemiological information by which OspC proteins from different strains of B. burgdorferi are grouped together. OspC antigens are chosen in order to constitute a representative sample of such groupings, so that the resulting vaccine provides the greatest cross-protectivity with the fewest number of antigens.

4. 发明申请

WO9857672A3 PROCESS FOR REDUCING THE CONCENTRATION OF VIRAL AND MOLECULAR PATHOGENS IN A BIOLOGICAL MATERIAL 审中-公开
标题翻译：减少生物材料中病毒和分子病原体浓度的方法
公开(公告)号：WO9857672A3
公开(公告)日：1999-03-18
申请号：PCT/AT9800143
申请日：1998-06-10
申请人： IMMUNO AG , EIBL JOHANN , DORNER FRIEDRICH , BARRETT NOEL , POELSLER GERHARD , LINNAU YENDRA
发明人： EIBL JOHANN , DORNER FRIEDRICH , BARRETT NOEL , POELSLER GERHARD , LINNAU YENDRA
IPC分类号： A61K35/14 , A61K39/395 , A61L2/00 , B01J41/04 , B01J41/20 , C07K1/18 , C07K16/00 , C07K16/06
CPC分类号： A61L2/0017 , A61L2/0011 , B01J41/20
摘要： A process is disclosed for reducing the concentration of viral and molecular pathogens in a biological material which contains one or several biological substances to be extracted. The biological material is mixed with an organic solvent, the biological material mixed with the solvent is brought into contact with an ion exchanger, pathogens are adsorbed by the ion exchange material and at least one of the biological substances to be extracted interacts to a reduced extent or not at all with the ion exchanger, then the ion exchanger with the adsorbed pathogens is separated from the biological material. A preparation of the biological substance with a reduced virus concentration is thus obtained.

5. 发明申请

WO9749812A3 PROCESS FOR EXTRACTING AND PURIFYING RECOMBINANT, NON-LIPIDISED OSP-PROTEIN 审中-公开
标题翻译：程序获得和重组清洗，非脂化OSP蛋白
公开(公告)号：WO9749812A3
公开(公告)日：1999-11-04
申请号：PCT/AT9700136
申请日：1997-06-19
申请人： IMMUNO AG , MITTERER ARTUR , TAUER CHRISTA , LIVEY IAN , DORNER FRIEDRICH
发明人： MITTERER ARTUR , TAUER CHRISTA , LIVEY IAN , DORNER FRIEDRICH
IPC分类号： C12N15/09 , A61K39/00 , A61K39/02 , A61P31/04 , C07K1/16 , C07K14/195 , C07K14/20 , C12N1/19 , C12N15/31 , C12P21/02 , C12R1/78
CPC分类号： C07K14/20 , A61K39/00
摘要： A recombinant, non-lipidised OspC is disclosed, as well as a process for preparing Osp-proteins and vaccines which contain these recombinant proteins.
摘要翻译：本发明公开了重组的OspC，其是非脂质化，制备OSP-蛋白和疫苗包含这些重组蛋白的方法。

6. 发明申请

WO0015251A3 INFLUENZA VIRUS VACCINE COMPOSITION 审中-公开
标题翻译：流感病毒疫苗成分
公开(公告)号：WO0015251A3
公开(公告)日：2000-08-24
申请号：PCT/AT9900223
申请日：1999-09-14
申请人： BAXTER AG , KISTNER OTFRIED , BARRETT NOEL , MUNDT WOLFGANG , DORNER FRIEDRICH
发明人： KISTNER OTFRIED , BARRETT NOEL , MUNDT WOLFGANG , DORNER FRIEDRICH
IPC分类号： A61K39/145 , A61K39/39 , A61P31/16
CPC分类号： A61K39/39 , A61K39/12 , A61K39/145 , A61K2039/525 , A61K2039/5252 , A61K2039/55505 , C12N2760/16134 , C12N2760/16234
摘要： Disclosed is an influenza virus vaccine containing an influenza virus antigen prepared from a cell culture with an influenza virus antigen content ranging from 1 mu g to 5 mu g/dose and aluminum as adjuvants and to a method for the production thereof.
摘要翻译：公开的是含有1克5克/剂量和铝之间亩亩流感病毒抗原含量作为佐剂以及它们的制备方法的细胞培养衍生的流感病毒抗原的流感病毒疫苗。

7. 发明申请

WO03049767A2 METHOD OF LARGE SCALE PRODUCTION OF HEPATITIS A VIRUS 审中-公开
标题翻译：大规模生产乙型肝炎病毒的方法
公开(公告)号：WO03049767A2
公开(公告)日：2003-06-19
申请号：PCT/EP0214012
申请日：2002-12-10
申请人： BAXTER HEALTHCARE SA , MEYER HEIDI , REITER MANFRED , MUNDT WOLFGANG , BARRETT NOEL , DORNER FRIEDRICH
发明人： MEYER HEIDI , REITER MANFRED , MUNDT WOLFGANG , BARRETT NOEL , DORNER FRIEDRICH
IPC分类号： A61K39/29 , C12N5/06 , C12N7/01 , C12N7/02
CPC分类号： C12N7/00 , A61K39/12 , A61K39/29 , A61K2039/5252 , C12N2770/32434 , C12N2770/32451
摘要： The present invention provides methods of large scale production of Hepatitis A Virus (HAV) on VERO cells bound to microcarrier. The invention also provides for methods of isolation of HAV from the cell culture supernatant of HAV infected VERO cells.
摘要翻译：本发明提供了在与微载体结合的VERO细胞上大规模生产甲型肝炎病毒（HAV）的方法。本发明还提供从HAV感染的VERO细胞的细胞培养物上清液中分离HAV的方法。

8. 发明申请

WO0047222A3 INACTIVATED INFLUENZA VIRUS VACCINE FOR NASAL OR ORAL ADMINISTRATION 审中-公开
标题翻译：流感病毒灭活疫苗鼻腔或口腔的应用
公开(公告)号：WO0047222A3
公开(公告)日：2001-10-11
申请号：PCT/AT0000023
申请日：2000-02-01
申请人： BAXTER VACCINE AG , BARRETT NOEL , KISTNER OTFRIED , GERENCER MARIJAN , DORNER FRIEDRICH
发明人： BARRETT NOEL , KISTNER OTFRIED , GERENCER MARIJAN , DORNER FRIEDRICH
IPC分类号： A61K39/145 , A61P31/16 , A61K39/39
CPC分类号： A61K39/145 , A61K39/12 , A61K2039/542 , A61K2039/543 , A61K2039/55505 , A61K2039/55544 , C12N2760/16134 , C12N2760/16234 , Y10S530/826
摘要： The invention relates to the use of a compound containing inactivated influenza virus antigen and aluminium as adjuvant, for the preparation of an influenza virus vaccine for nasal or oral administration for the prophylaxis of influenza virus infections. Said vaccine is especially suitable for inducing a mucosal IgA immune response and systemic IgG immune response.
摘要翻译：本发明涉及使用含有灭活的流感病毒抗原和铝作为制备用于经鼻或口服给药的流感病毒疫苗的流感病毒感染的预防佐剂的组合物。特别地，该疫苗能够诱导粘膜IgA和IgG的全身免疫应答。

9. 发明申请

WO2012052131A9 RECHARGEABLE BATTERY HAVING A BENDING SUPPORT AND PRODUCTION METHOD THEREFOR 审中-公开
公开(公告)号：WO2012052131A9
公开(公告)日：2012-06-21
申请号：PCT/EP2011005130
申请日：2011-10-13
申请人： MAGNA E CAR SYSTEMS GMBH & CO , DORNER FRIEDRICH
发明人： DORNER FRIEDRICH
IPC分类号： H01M2/10 , H01M10/50
CPC分类号： H01M2/1077 , H01M2/1083 , H01M10/613 , H01M10/625 , H01M10/647 , H01M10/6555 , H01M10/6556
摘要： A rechargeable battery (1a.. 1d) is specified, which comprises at least one bending support (2a, 2b) having a plurality of attachments/contact points (A, B) which are at a distance from one another, for attachment or mounting of the rechargeable battery (1a.. 1d). A plurality of voltage-producing cells (3) are attached to the longitudinal face of the bending support (2a, 2b) and come to rest at least partially between the attachment/contact points (A, B). In addition, the bending support (2a, 2b) has a tubular area (D), which is designed for guidance of a gaseous or liquid heat carrier for controlling the temperature of the rechargeable battery (1a.. 1d). Finally, recesses (E) are arranged in the area of the cells (3), in that section (C) of the bending support (2a, 2b) which is in the form of a plate. Furthermore, a production method is specified for a rechargeable battery (1a.. 1d) such as this.

10. 发明申请

WO2012052131A2 RECHARGEABLE BATTERY HAVING A BENDING SUPPORT AND PRODUCTION METHOD THEREFOR 审中-公开
标题翻译：具有弯曲支撑的蓄积器及其制造方法
公开(公告)号：WO2012052131A2
公开(公告)日：2012-04-26
申请号：PCT/EP2011005130
申请日：2011-10-13
申请人： MAGNA E CAR SYSTEMS GMBH & CO , DORNER FRIEDRICH
发明人： DORNER FRIEDRICH
IPC分类号： H01M2/10
CPC分类号： H01M2/1077 , H01M2/1083 , H01M10/613 , H01M10/625 , H01M10/647 , H01M10/6555 , H01M10/6556
摘要： A rechargeable battery (1a.. 1d) is specified, which comprises at least one bending support (2a, 2b) having a plurality of attachments/contact points (A, B) which are at a distance from one another, for attachment or mounting of the rechargeable battery (1a.. 1d). A plurality of voltage-producing cells (3) are attached to the longitudinal face of the bending support (2a, 2b) and come to rest at least partially between the attachment/contact points (A, B). In addition, the bending support (2a, 2b) has a tubular area (D), which is designed for guidance of a gaseous or liquid heat carrier for controlling the temperature of the rechargeable battery (1a.. 1d). Finally, recesses (E) are arranged in the area of the cells (3), in that section (C) of the bending support (2a, 2b) which is in the form of a plate. Furthermore, a production method is specified for a rechargeable battery (1a.. 1d) such as this.
摘要翻译：它是所示的蓄能器（1a，1d），其包括至少一个弯曲梁（2a，2b），其具有用于附接或放置电池（1a，1d）的多个间隔开的安装/支撑点（A，B）。在弯曲梁（2a，2b）的纵向侧上固定有多个电压生成单元（3），其至少部分地停留在附接/支撑点（A，B）之间。此外，弯曲梁（2a，2b）具有管状区域（D），该管状区域被设计成引导气体或液体热载体以用于蓄热器（1a，1d）的温度控制。最后，在弯曲支撑件（2a，2b）的板形部分（C）中布置在单元（3）的区域中的凹部（E）。另外，给出了这种蓄电池（1a，1d）的制造方法。

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