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1. 发明申请

WO2009056500A2 A RADIO RECEIVER IN A WIRELESS COMMUNICATIONS SYSTEM 审中-公开
标题翻译：无线通信系统中的无线电接收器
公开(公告)号：WO2009056500A2
公开(公告)日：2009-05-07
申请号：PCT/EP2008064464
申请日：2008-10-24
申请人： ICERA INC , LUSCHI CARLO , WALKER SIMON , ALLPRESS STEVE , JONES PHILIP
发明人： LUSCHI CARLO , WALKER SIMON , ALLPRESS STEVE , JONES PHILIP
IPC分类号： H04L25/03 , H04L25/02
CPC分类号： H04L25/03114 , H04L25/0212 , H04L25/0222 , H04L2025/03566 , H04L2025/03726
摘要： A radio receiver and corresponding method for a wireless communications system. The receiver comprises: channel equalisation means arranged to receive samples of an incoming signal and to generate an equalised output, the channel equalisation means comprising means for processing the digital samples in accordance with an equaliser algorithm. The receiver further comprises: means for estimating parameters of a channe! over which the incoming signal has been transmitted, and means for selecting from a plurality of equaliser algorithms an equaliser algorithm for execution by the processing means based on at least one of the estimated channel parameters.
摘要翻译：无线电接收机和用于无线通信系统的相应方法。该接收机包括：通道均衡装置，用于接收输入信号的采样并产生均衡输出，通道均衡装置包括根据均衡器算法处理数字采样的装置。该接收机还包括：用于估计信道参数的装置，基于所估计的信道参数中的至少一个，用于从多个均衡器算法中选择由处理装置执行的均衡器算法的装置。

2. 发明申请

WO2009056499A2 A RADIO RECEIVER IN A WIRELESS COMMUNICATIONS SYSTEM 审中-公开
标题翻译：无线通信系统中的无线接收器
公开(公告)号：WO2009056499A2
公开(公告)日：2009-05-07
申请号：PCT/EP2008064461
申请日：2008-10-24
申请人： ICERA INC , LUSCHI CARLO , HUCKETT SIMON , WALKER SIMON , ALLPRESS STEVE , JONES PHILIP
发明人： LUSCHI CARLO , HUCKETT SIMON , WALKER SIMON , ALLPRESS STEVE , JONES PHILIP
IPC分类号： H04L25/02 , H04L25/03
CPC分类号： H04L25/03114 , H04B2201/7071 , H04L25/0212 , H04L2025/03566 , H04L2025/03726
摘要： A method and corresponding receiver for processing radio signals in a radio receiver. The method comprises: receiving digital samples of an incoming radio signal and processing those samples in accordance with an equaliser algorithm utilising a set of equaliser parameters to generate an equalised output; estimating at least one parameter of a channel over which the incoming signal has been transmitted; and selecting at least one of the equaliser parameters based on at least one of said estimated channel parameters.
摘要翻译：一种在无线电接收机中处理无线电信号的方法和相应的接收机。该方法包括：接收输入无线电信号的数字样本并根据均衡器算法使用一组均衡器参数处理这些样本以产生均衡的输出; 估计已经发送了所述输入信号的信道的至少一个参数; 以及基于所述估计的信道参数中的至少一个来选择所述均衡器参数中的至少一个。

3. 发明申请

WO2009056505A1 WIRELESS RECEIVER WITH RECEIVE DIVERSITY 审中-公开
标题翻译：带有接收分集的无线接收器
公开(公告)号：WO2009056505A1
公开(公告)日：2009-05-07
申请号：PCT/EP2008064474
申请日：2008-10-24
申请人： ICERA INC , LUSCHI CARLO , HUCKETT SIMON , ALLPRESS STEVE , JONES PHILIP
发明人： LUSCHI CARLO , HUCKETT SIMON , ALLPRESS STEVE , JONES PHILIP
IPC分类号： H04B7/08
CPC分类号： H04B7/0874 , H04B7/02 , H04B7/04
摘要： A wireless receiver and corresponding method for receiving a signal transmitted by a transmitter. The receiver comprises: a plurality of antennas each for receiving a version of the signal via a different propagation channel and providing that version at a respective input, and signal processing means configured to operate diversity processing of a supplied number of the inputs for use in performing detection of the signal. The receiver further comprises: channel parameter estimation means configured to estimate one or more channel parameters on the propagation channels; and selection means configured to select only a subset of the inputs to implement a specific dimensionality of the receiver diversity processing, in dependence on the one or more channel parameters indicative of channel conditions on the propagation channels.
摘要翻译：一种用于接收由发射机发射的信号的无线接收机和相应的方法。接收机包括：多个天线，每个天线用于经由不同的传播信道接收信号的版本并且在相应的输入处提供该版本;以及信号处理装置，配置为操作所提供的多个输入的分集处理以用于执行信号的检测。接收机还包括：信道参数估计装置，被配置为估计传播信道上的一个或多个信道参数; 以及选择装置，被配置为根据指示传播信道上的信道条件的一个或多个信道参数，仅选择输入的子集来实现接收机分集处理的特定维度。

4. 发明申请

WO2012096929A3 HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF 审中-公开
标题翻译：异构体化合物及其使用方法
公开(公告)号：WO2012096929A3
公开(公告)日：2012-10-11
申请号：PCT/US2012020734
申请日：2012-01-10
申请人： SUNOVION PHARMACEUTICALS INC , CAMPBELL JOHN EMMERSON , JONES PHILIP , HEWITT MICHAEL CHARLES
发明人： CAMPBELL JOHN EMMERSON , JONES PHILIP , HEWITT MICHAEL CHARLES
IPC分类号： C07D471/04 , A61K31/4738 , A61P25/00 , C07D403/06 , C07D471/12 , C07D487/04
CPC分类号： C07D519/00 , A61K31/4375 , A61K31/4745 , A61K31/4985 , A61K31/519 , A61K31/5383 , A61K45/06 , C07D471/04 , C07D487/04
摘要： Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and metabolic disorders, including, but not limited to, e.g., neurological disorders, psychosis, schizophrenia, obesity, and diabetes.
摘要翻译：本文提供了杂芳基化合物，其合成方法，包含该化合物的药物组合物及其用途。在一个实施方案中，本文提供的化合物可用于治疗，预防和/或治疗各种疾病，例如CNS障碍和代谢紊乱，包括但不限于例如神经障碍，精神病，精神分裂症，肥胖症，和糖尿病。

5. 发明申请

WO2006003388A8 COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY DISORDERS 审中-公开
标题翻译：用于治疗炎症性疾病的组合物和方法
公开(公告)号：WO2006003388A8
公开(公告)日：2007-06-21
申请号：PCT/GB2005002553
申请日：2005-06-29
申请人： DOMANTIS LTD , IGNATOVICH OLGA , DE WILDT RUDOLF , WOOLVEN BENJAMIN , GRANT STEVEN , JONES PHILIP , BASRAN AMRIK , BREWIS NEIL
发明人： IGNATOVICH OLGA , DE WILDT RUDOLF , WOOLVEN BENJAMIN , GRANT STEVEN , JONES PHILIP , BASRAN AMRIK , BREWIS NEIL
IPC分类号： C07K16/24 , A61K39/395 , A61P19/02 , C07K16/22
CPC分类号： C07K16/22 , A61K47/60 , A61K47/6879 , A61K2039/505 , C07K16/18 , C07K16/241 , C07K16/40 , C07K2317/21 , C07K2317/31 , C07K2317/34 , C07K2317/55 , C07K2317/569 , C07K2317/622 , C07K2317/626 , C07K2317/92 , C07K2319/00
摘要： The invention relates to compositions and methods for treating inflammatory disorders. More specifically, the invention relates to antibody compositions and their use in the treatment of inflammatory disorders.
摘要翻译：本发明涉及用于治疗炎症性疾病的组合物和方法。更具体地，本发明涉及抗体组合物及其在治疗炎症性疾病中的用途。

6. 发明申请

WO2012054364A3 BICYCLIC DIAMINES AS JANUS KINASE INHIBITORS 审中-公开
标题翻译：作为JANUS KINASE INHIBITORS的双相DIAMINES
公开(公告)号：WO2012054364A3
公开(公告)日：2014-04-10
申请号：PCT/US2011056498
申请日：2011-10-17
申请人： MERCK SHARP & DOHME , GUERIN DAVID JOSEPH , BRUBAKER JASON D , MARTINEZ MICHELLE , JUNG JOON O , ANTHONY NEVILLE J , SCOTT MARK E , CAMMARANO CAROLYN MICHELE , HOFFMAN DAWN MARIE MAMPREIAN , WOO HYUN CHONG , DINSMORE CHRISTOPHER J , JONES PHILIP
发明人： GUERIN DAVID JOSEPH , BRUBAKER JASON D , MARTINEZ MICHELLE , JUNG JOON O , ANTHONY NEVILLE J , SCOTT MARK E , CAMMARANO CAROLYN MICHELE , HOFFMAN DAWN MARIE MAMPREIAN , WOO HYUN CHONG , DINSMORE CHRISTOPHER J , JONES PHILIP
IPC分类号： A61K31/34 , A61K31/44
CPC分类号： C07D471/04 , A61K31/519 , C07D519/00
摘要： The instant invention provides compounds of formula I which are Jak inhibitors, and as such are useful for the treatment of Jak-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.
摘要翻译：本发明提供了作为Jak抑制剂的式I化合物，因此可用于治疗Jak介导的疾病如类风湿性关节炎，哮喘，COPD和癌症。

7. 发明申请

WO2012009000A3 NOVEL FUSED PYRAZOLE DERIVATIVES AND THEIR USE AS ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS 审中-公开
标题翻译：新型掺杂的吡唑衍生物及其作为代谢谷氨酸受体的独立调节剂
公开(公告)号：WO2012009000A3
公开(公告)日：2013-04-18
申请号：PCT/US2011001206
申请日：2011-07-11
申请人： ADDEX PHARMACEUTICALS SA , MERCK SHARP & DOHME , BOLEA CHRISTELLE , CELANIRE SYLVAIN , TANG LAM , JONES PHILIP , LIVERTON NIGEL J , SOLL RICHARD , DONG JINCHAO , LEI ZHIYU , LIU FUQUING , KONG YANLING , JU YI , ZHANG HAOYONG , WEI JIEPING , WEI QAIOXIN , ZHANG MINGXIANG , LUO YUNFU
发明人： BOLEA CHRISTELLE , CELANIRE SYLVAIN , TANG LAM , JONES PHILIP , LIVERTON NIGEL J , SOLL RICHARD , DONG JINCHAO , LEI ZHIYU , LIU FUQUING , KONG YANLING , JU YI , ZHANG HAOYONG , WEI JIEPING , WEI QAIOXIN , ZHANG MINGXIANG , LUO YUNFU
IPC分类号： A01N43/42
CPC分类号： C07D513/12 , A23L27/2056 , A23L33/10 , A23V2002/00 , A61K9/0019 , A61K9/0095 , A61K9/06 , A61K9/10 , A61K9/2059 , A61K31/429 , A61K31/433 , A61K31/4439 , A61K31/506 , A61K31/55 , A61K45/06 , C07D513/04 , C07D513/14 , A61K2300/00 , A23V2200/16 , A23V2200/322 , A23V2200/328
摘要： The present invention relates to novel compounds of Formula (I), wherein M, A and Y are defined as in Formula (I); invention compounds are modulators of metabotropic glutamate receptors - subtype 4 ("mGluR4") which are useful for the treatment or prevention of central nervous system disorders as well as other disorders modulated by mGluR4 receptors. The invention is also directed to pharmaceutical compositions and the use of such compounds in the manufacture of medicaments, as well as to the use of such compounds for the prevention and treatment of such diseases in which mGluR4 is involved.
摘要翻译：本发明涉及新的式（I）化合物，其中M，A和Y如式（I）所定义; 本发明化合物是代谢型谷氨酸受体的调节剂 - 亚型4（“mGluR4”），其可用于治疗或预防中枢神经系统疾病以及由mGluR4受体调节的其它病症。本发明还涉及药物组合物和这些化合物在制备药物中的用途，以及这些化合物用于预防和治疗涉及mGluR4的疾病的用途。

8. 发明申请

WO2006103399A8 HIV INTEGRASE INHIBITORS 审中-公开
标题翻译：艾滋病毒整合抑制剂
公开(公告)号：WO2006103399A8
公开(公告)日：2007-11-01
申请号：PCT/GB2006001062
申请日：2006-03-22
申请人： ANGELETTI P IST RICHERCHE BIO , CECERE GIUSEPPE , FERREIRA MARIA DEL ROSARIO RIC , JONES PHILIP , PACE PAOLA , PETROCCHI ALESSIA , SUMMA VINCENZO
发明人： CECERE GIUSEPPE , FERREIRA MARIA DEL ROSARIO RIC , JONES PHILIP , PACE PAOLA , PETROCCHI ALESSIA , SUMMA VINCENZO
IPC分类号： C07D487/04 , A61K31/519 , A61K31/5377 , A61K31/542 , A61K31/551 , A61K31/553 , A61P31/00 , C07D487/14 , C07D493/20 , C07D498/04 , C07D513/04 , C07D513/14
CPC分类号： C07D487/04 , C07D487/14 , C07D513/04 , C07D513/14
摘要： Compounds of Formula I are inhibitors of FHV integrase and inhibitors of FHV replication (I), wherein m, n, X, R l , R 2 , R 3 , R 4 , R 5 , R 6 R 7 ; R 8 R 9 and R 10 are defined herein. The compounds are useful for the prophylaxis or treatment of infection by HTV and the prophylaxis, treatment , or delay in the onset of AIDS. The compounds are employed against HTV infection and ADDS as compounds per se or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
摘要翻译：式I化合物是FHV整合酶的抑制剂和FHV复制抑制剂（I），其中m，n，X，R 1，R 2，R 3 R 4，R 5，R 6，R 6，R 7，本文定义了R 9和R 10和R 10。该化合物可用于预防或治疗HTV感染以及预防，治疗或延迟AIDS发病。该化合物用于抗HTV感染和ADDS作为化合物本身或以药学上可接受的盐的形式。化合物及其盐可以用作药物组合物中的成分，任选与其它抗病毒剂，免疫调节剂，抗生素或疫苗组合使用。

9. 发明申请

WO2005074513A3 N-BENZYL-3,4-DIHYROXYPYRIDINE-2-CARBOXAMIDE AND N-BENZYL-2,3-DIHYDROXYPYRIDINE-4-CARBOXAMIDE COMPOUNDS USEFUL AS HIV INTEGRASE INHIBITORS 审中-公开
标题翻译：用作HIV整合酶抑制剂的N-苄基-3,4-二氧代吡啶-2-羧酰胺和N-苄基-2,3-二羟基吡啶-4-羧酰胺化合物
公开(公告)号：WO2005074513A3
公开(公告)日：2005-09-29
申请号：PCT/US2005002472
申请日：2005-01-26
申请人： MERCK & CO INC , ANGELETTI P IST RICHERCHE BIO , JONES PHILIP , WILLIAMS PETER D , MORRISSETTE MATTHEW M , KUO MICHELLE SPARKS , VACCA JOSEPH P
发明人： JONES PHILIP , WILLIAMS PETER D , MORRISSETTE MATTHEW M , KUO MICHELLE SPARKS , VACCA JOSEPH P
IPC分类号： A61K31/44 , C07D211/74
CPC分类号： C07D213/64 , C07D213/69 , C07D213/81 , C07D401/12 , C07D401/14 , C07D403/14 , C07D409/06 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04
摘要： N-Benzyl-dihydroxypyridine carboxamide compounds are inhibitors of HIV integrase and inhibitors of HIV replication. In one embodiment, the dihydroxypyridine carboxamides are of Formula (I) wherein Q is Formula (II) or Formula (III); T is Formula (IV); and R , R , X ,X ,X , and Y are defined herein. The compounds are useful in the prevention and treatment of infection by HIV and in the prevention, delay in the onset, and treatment of AIDS. The compounds are employed against HIV infection and AIDS as compounds per se or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
摘要翻译： N-苄基 - 二羟基吡啶甲酰胺化合物是HIV整合酶抑制剂和HIV复制抑制剂。在一个实施方案中，二羟基吡啶甲酰胺具有式（I），其中Q是式（II）或式（III）; T是式（IV）; 并且R 1，R 2，X 1，X 2，X 3和Y 1如本文所定义。这些化合物可用于预防和治疗HIV感染以及预防，延缓艾滋病的发作和治疗。这些化合物本身作为化合物或以药学上可接受的盐的形式用于抗HIV感染和AIDS。化合物及其盐可以用作药物组合物中的成分，任选地与其他抗病毒剂，免疫调节剂，抗生素或疫苗组合使用。

10. 发明申请

WO2011150156A3 HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF 审中-公开
标题翻译：杂芳基化合物及其使用方法
公开(公告)号：WO2011150156A3
公开(公告)日：2012-04-19
申请号：PCT/US2011038057
申请日：2011-05-26
申请人： SUNOVION PHARMACEUTICALS INC , CAMPBELL JOHN EMMERSON , HEWITT MICHAEL CHARLES , JONES PHILIP , XIE LINGHONG
发明人： CAMPBELL JOHN EMMERSON , HEWITT MICHAEL CHARLES , JONES PHILIP , XIE LINGHONG
IPC分类号： C07D403/06 , A61K31/498 , A61K31/519 , A61P25/00 , C07D401/06 , C07D471/04
CPC分类号： C07D498/06 , A61K31/4164 , A61K31/4178 , A61K31/4709 , A61K31/498 , A61K31/4985 , A61K31/506 , A61K31/517 , A61K31/5383 , C07D233/58 , C07D401/06 , C07D401/14 , C07D403/06 , C07D405/14 , C07D409/06 , C07D409/14 , C07D413/06 , C07D417/06 , C07D471/04 , C07D471/06 , C07D471/14 , C07D487/04 , C07D491/056 , C07D498/04 , C07D498/14 , C07D519/00
摘要： Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and metabolic disorders, including, but not limited to, e.g., neurological disorders, psychosis, schizophrenia, obesity, and diabetes.
摘要翻译：本文提供了杂芳基化合物，它们的合成方法，包含所述化合物的药物组合物，以及它们的使用方法。在一个实施方案中，本文提供的化合物可用于治疗，预防和/或控制各种病症，例如CNS病症和代谢病症，包括但不限于例如神经病症，精神病，精神分裂症，肥胖症，和糖尿病。

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