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1. 发明申请

WO2007035723A2 COMPOSITIONS AND METHODS COMPRISING PANAX SPECIES 审中-公开
标题翻译：包含PANAX种类的组合物和方法
公开(公告)号：WO2007035723A2
公开(公告)日：2007-03-29
申请号：PCT/US2006036464
申请日：2006-09-19
申请人： HERBALSCIENCE SINGAPORE PTE LTD , GOW ROBERT T , SYPERT GEORGE W , YAN XUN , LI DAN
发明人： GOW ROBERT T , SYPERT GEORGE W , YAN XUN , LI DAN
IPC分类号： A61K36/254 , A61K31/704
CPC分类号： A61K36/258 , A61K31/704
摘要： Compositions comprising elevated amounts of a ginsenosides, polyacetylenes, essential oil and/or polysaccharide are described, as are preferred extraction methods.
摘要翻译：描述了包含升高量的人参皂苷，聚乙炔，精油和/或多糖的组合物，作为优选的提取方法。

2. 发明申请

WO2007109210A3 EXTRACTS AND METHODS COMPRISING CURCUMA SPECIES 审中-公开
标题翻译：提取和包含MA MA种的方法
公开(公告)号：WO2007109210A3
公开(公告)日：2008-04-10
申请号：PCT/US2007006771
申请日：2007-03-16
申请人： HERBALSCIENCE SINGAPORE PTE LTD , LI DAN , GOW ROBERT T , SYPERT GEORGE W , MANVILLE H BROCK , ALBERTE RANDALL S
发明人： LI DAN , GOW ROBERT T , SYPERT GEORGE W , MANVILLE H BROCK , ALBERTE RANDALL S
IPC分类号： A61K36/906
CPC分类号： A61K36/9066 , A23L33/105 , A23V2002/00 , A23V2250/21 , A23V2200/30 , A23V2250/2112
摘要： The present invention relates to extracts of curcuma species plant material using supercritical CO2 extraction methods, methods of treating a subject suffering from suffering from amyloid plaque aggregation or fibril formation associated with, for example, Alzheimer's disease, and methods of inhibiting amyloid plaque aggregation or fibril formation in tissue thereof.
摘要翻译：本发明涉及使用超临界CO 2提取方法的姜黄种植物材料的提取物，治疗患有与例如阿尔茨海默氏病相关的淀粉样蛋白斑块聚集或原纤维形成的受试者的方法，以及抑制淀粉样蛋白斑块聚集或原纤维的方法在其组织中形成。

3. 发明申请

WO2007109801A3 EXTRACTS AND METHODS COMPRISING GANODERMA SPECIES 审中-公开
标题翻译：包含灵芝属植物的提取物和方法
公开(公告)号：WO2007109801A3
公开(公告)日：2007-11-08
申请号：PCT/US2007064829
申请日：2007-03-23
申请人： HERBALSCIENCE SINGAPORE PTE LTD , GOW ROBERT T , LI DAN , SYPERT GEORGE W , ALBERTE RANDALL S
发明人： GOW ROBERT T , LI DAN , SYPERT GEORGE W , ALBERTE RANDALL S
IPC分类号： A61K36/00 , A61K31/35
CPC分类号： A61K36/074
摘要： The present invention relates to extracts of ganoderma species plant material prepared by supercritical CO 2 extractions.
摘要翻译：本发明涉及通过超临界CO 2提取制备的灵芝物种植物材料的提取物。

4. 发明申请

WO2008070783A3 COMPOSITIONS AND METHODS COMPRISING ZINGIBER SPECIES 审中-公开
标题翻译：包含ZINGIBER种类的组合物和方法
公开(公告)号：WO2008070783A3
公开(公告)日：2008-09-12
申请号：PCT/US2007086653
申请日：2007-12-06
申请人： HERBALSCIENCE SINGAPORE PTE LTD , LI DAN , SYPERT GEORGE W , GOW ROBERT T
发明人： LI DAN , SYPERT GEORGE W , GOW ROBERT T
IPC分类号： A61K36/906
CPC分类号： A61K36/9068 , A61K31/12 , A61K31/715
摘要： An aspect of the present invention relates to compositions comprising a gingerol, for example, compositions comprising gingerol in an amount greater than about 2% by weight. In some aspects of the invention, the composition comprises 6-gingerol, 8-gingerol, 10- gingerol, 6-shagaol, or combinations thereof. Another aspect of the invention relates to a method for extracting a ginger species comprising, sequentially extracting a ginger species plant material to yield an essential oil fraction, a gingerol fraction, a phenolic fraction, and a polysaccharide fraction, wherein the essential oil and gingerol fractions are derived by extracting plant feedstock material by supercritical carbon dioxide extraction, the phenolic fraction is extracted from the plant feedstock material or from the remainder of the essential oil and gingerol extractions by hydroalcoholic extraction, and the polysaccharide fraction is derived by water extraction of the remainder of the phenolic extraction.
摘要翻译：本发明的一个方面涉及包含姜酚的组合物，例如包含量大于约2重量％的姜醇的组合物。在本发明的一些方面，组合物包含6-姜酚，8-姜酚，10-姜醇，6-三聚醇或其组合。本发明的另一方面涉及一种用于提取姜物种的方法，其包括依次提取姜物种植物材料以产生精油馏分，姜酚馏分，酚类馏分和多糖馏分，其中精油和姜醇馏分是通过超临界二氧化碳萃取提取植物原料材料而得到的，酚类级分是通过水醇提取从植物原料或其余精油和姜酚提取物中提取的，并且通过水提取其余部分的酚萃取。

5. 发明申请

WO2008036932A3 COMPOSITIONS AND METHODS COMPRISING BOSWELLIA SPECIES 审中-公开
标题翻译：组合物和方法包括波斯尼亚种
公开(公告)号：WO2008036932A3
公开(公告)日：2008-07-10
申请号：PCT/US2007079211
申请日：2007-09-21
申请人： HERBALSCIENCE SINGAPORE PTE LTD , LI DAN , GOW ROBERT T , SYPERT GEORGE W
发明人： LI DAN , GOW ROBERT T , SYPERT GEORGE W
IPC分类号： A61K31/015
CPC分类号： A61K36/324 , A61K31/19
摘要： In certain aspects the invention features novel compositions and pharmaceutical preparations of the same. In certain embodiments, the compositions comprise a- and/or ß- boswellic acid and/or their C-acetates in an amount greater than 65% by weight.
摘要翻译：在某些方面，本发明的特征在于其新颖的组合物和药物制剂。在某些实施方案中，组合物包含大于65重量％的α-和/或β-乳香酸和/或它们的C-乙酸酯。

6. 发明申请

WO2007109802A3 EXTRACTS AND METHODS COMPRISING GREEN TEA SPECIES 审中-公开
标题翻译：包含绿茶种类的提取物和方法
公开(公告)号：WO2007109802A3
公开(公告)日：2007-11-22
申请号：PCT/US2007064830
申请日：2007-03-23
申请人： HERBALSCIENCE SINGAPORE PTE LTD , GOW ROBERT T , SYPERT GEORGE W , LI DAN , ALBERTE RANDALL S
发明人： GOW ROBERT T , SYPERT GEORGE W , LI DAN , ALBERTE RANDALL S
IPC分类号： A61K36/82
CPC分类号： A61K36/82
摘要： The present invention relates to extracts of green tea species plant material prepared by supercritical CO 2 extractions methods.
摘要翻译：本发明涉及通过超临界CO 2提取法制备的绿茶种植物材料的提取物。

7. 发明申请

WO2007109804A3 EXTRACTS AND METHODS COMPRISING CINNAMON SPECIES 审中-公开
标题翻译：提取物和包含中华物种的方法
公开(公告)号：WO2007109804A3
公开(公告)日：2008-09-04
申请号：PCT/US2007064832
申请日：2007-03-23
申请人： HERBALSCIENCE SINGAPORE PTE LTD , GOW ROBERT T , SYPERT GEORGE W , LI DAN , ALBERTE RANDALL S
发明人： GOW ROBERT T , SYPERT GEORGE W , LI DAN , ALBERTE RANDALL S
IPC分类号： A23L1/22
CPC分类号： C07C47/232 , A23L27/12 , A23L33/105 , A23V2002/00 , A61K36/54 , C07C29/76 , C07C31/125 , C07C33/02 , C07C33/14 , C07C33/32 , C07C35/30 , C07C45/78 , C07C47/27 , C07C47/277 , C07C47/54 , C07C51/47 , C07C67/56 , C07D311/40 , C07H17/02 , Y02P20/544 , C07C57/44 , C07C69/618 , C07C69/007 , A23V2200/15 , A23V2250/708 , A23V2250/264 , C07C69/157
摘要： The present invention relates to extracts of cinnamon species plant material prepared by supercritical CO 2 extractions methods.
摘要翻译：本发明涉及通过超临界CO 2萃取方法制备的肉桂种植物材料的提取物。

8. 发明申请

WO2007109600A2 EXTRACTIONS AND METHODS COMPRISING ELDER SPECIES 审中-公开
标题翻译：包含老化种的提取物和方法
公开(公告)号：WO2007109600A2
公开(公告)日：2007-09-27
申请号：PCT/US2007064286
申请日：2007-03-19
申请人： HERBALSCIENCE SINGAPORE PTE LTD , GOW ROBERT T , SYPERT GEORGE W , LI DAN , ALBERTE RANDALL S
发明人： GOW ROBERT T , SYPERT GEORGE W , LI DAN , ALBERTE RANDALL S
IPC分类号： A61K36/73 , A61K36/35 , A61K127/00 , A61K131/00 , A61K133/00 , A61P31/12 , A61P31/16 , A61P31/18 , A61P31/22 , C07H17/00
CPC分类号： A61K36/73 , A23L33/105 , A23L33/12 , A23V2002/00 , A61K36/35 , A23V2200/324 , A23V2250/21 , A23V2250/2117 , A23V2250/50 , A23V2250/186 , A23V2250/2116 , A23V2250/08 , A23V2250/2104
摘要： The present invention relates to extracts of elder species plant material prepared by supercritical CO 2 extractions methods, methods of treating viruses in a subject and methods of inhibiting viral infections in cells thereof.
摘要翻译：本发明涉及通过超临界CO 2萃取方法制备的老化物种植物材料的提取物，治疗受试者中的病毒的方法以及抑制其细胞中的病毒感染的方法。

9. 发明申请

WO2005041997A8 METHODS AND COMPOSITIONS COMPRISING ILEX 审中-公开
标题翻译：包含ILEX的方法和组合物
公开(公告)号：WO2005041997A8
公开(公告)日：2006-08-10
申请号：PCT/US2004035098
申请日：2004-10-25
申请人： HERBALSCIENCE LLC , GOW ROBERT T , SYPERT GEORGE W , PIERCE JOHN W , MARENTIS RODGE M , LI DAN , YAN XUN
发明人： GOW ROBERT T , SYPERT GEORGE W , PIERCE JOHN W , MARENTIS RODGE M , LI DAN , YAN XUN
IPC分类号： A23F3/00 , A61K31/522 , A61K36/00 , A61K36/185
CPC分类号： A61K36/185
摘要： The present invention comprises methods for making compositions derived from Ilex species, particularly Ilex paraguariensis, having lowered caffeine and tannin concentrations, compositions made by such methods, oral delivery formulations, and methods of use of such compositions. In particular, the present invention comprises methods for making maté compositions that have a predetermined characeteristic, such as a lowered amount of caffeine, elevated amounts of caffeoyls, and/or lowered amounts of tannin compounds compared to the native maté plant materials. Further, the invention comprises methods of additional processing steps tp produce compositions having a predetermined alkaloid ratio or profiles to meet particular considerations for final products. The compositions of the present invention may be processed for specific uses such as tablets or other oral delivery vehicles. These compositions may be used in methods for treatment of physiological and medical conditions.
摘要翻译：本发明包括用于制备衍生自具有降低的咖啡因和单宁浓度的Ilex种，特别是白僵菌的组合物的组合物的方法，通过这些方法制备的组合物，口服递送制剂和使用该组合物的方法。特别地，本发明包括与天然植物材料相比制备具有预定特征的maté组合物的方法，例如降低量的咖啡因，升高的咖啡因量和/或降低量的单宁化合物。此外，本发明包括另外的加工步骤的方法，tp产生具有预定生物碱比例或轮廓的组合物以满足最终产品的特定考虑。本发明的组合物可以用于特定用途如片剂或其它口服递送载体。这些组合物可用于治疗生理和医学状况的方法。

10. 发明申请

WO2009149288A3 EXTRACTS OF CRANBERRY AND METHODS OF USING THEREOF 审中-公开
标题翻译：藤蔓提取物及其使用方法
公开(公告)号：WO2009149288A3
公开(公告)日：2010-03-25
申请号：PCT/US2009046302
申请日：2009-06-04
申请人： HERBALSCIENCE GROUP LLC , ALBERTE RANDALL S , ROSCHEK WILLIAM P , LI DAN
发明人： ALBERTE RANDALL S , ROSCHEK WILLIAM P , LI DAN
IPC分类号： A61K36/45 , A23L1/30 , A61K9/06 , A61K36/54 , A61P13/00 , A61P31/04
CPC分类号： A61K9/0034 , A23L33/105 , A23V2002/00 , A61K9/0014 , A61K9/7023 , A23V2250/21
摘要： The present disclosure relates in part to extracts of cranberry (Vaccinium macrocarpon) comprising an enriched amount of certain compounds having anti-infective activity, e.g. antibacterial and/or antifungal activity, e.g. activity against C. albicans. Another aspect of the disclosure relates to combined cranberry and cinnamon extracts. In certain embodiments, these combined extracts have been optimized to control urinary tract infections caused by E. coli, S. aureus and C. albicans. Certain embodiments of the extract are enriched in bioactive compounds that have been shown to inhibit C. albicans adhesion and/or bio film formation and its growth in vitro. In another aspect of the disclosure, the extracts are enriched in bioactives derived from cranberry and cinnamon that have been shown to inhibit the attachment and the growth of common urinary tract pathogens like E. coli, S. aureus and C. albicans.
摘要翻译：本公开部分涉及包含富集量的某些具有抗感染活性的化合物的蔓越莓（牛痘macrocarpon）的提取物。抗菌和/或抗真菌活性，例如针对白色念珠菌的活性。本公开的另一方面涉及组合的蔓越莓和肉桂提取物。在某些实施方案中，这些组合的提取物已被优化以控制由大肠杆菌，金黄色葡萄球菌和白色念珠菌引起的尿路感染。提取物的某些实施方案富含生物活性化合物，其已被证明可抑制白色念珠菌粘附和/或生物膜形成及其体外生长。在本公开的另一方面，提取物富含衍生自蔓越莓和肉桂的生物活性物质，其已被证明可抑制普通尿道病原体如大肠杆菌，金黄色葡萄球菌和白色念珠菌的附着和生长。

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