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1. 发明申请

WO2005041997A1 METHODS AND COMPOSITIONS COMPRISING ILEX 审中-公开
标题翻译：包含ILEX的方法和组合
公开(公告)号：WO2005041997A1
公开(公告)日：2005-05-12
申请号：PCT/US2004/035098
申请日：2004-10-25
申请人： HERBALSCIENCE LLC? , GOW, Robert, T. , SYPERT, George, W. , PIERCE, John, W. , MARENTIS, Rodge, M. , LI, Dan? , YAN, Xun?
发明人： GOW, Robert, T. , SYPERT, George, W. , PIERCE, John, W. , MARENTIS, Rodge, M. , LI, Dan? , YAN, Xun?
IPC分类号： A61K35/78
CPC分类号： A61K36/185
摘要： The present invention comprises methods for making compositions derived from Ilex species, particularly Ilex paraguariensis , having lowered caffeine and tannin concentrations, compositions made by such methods, oral delivery formulations, and methods of use of such compositions. In particular, the present invention comprises methods for making maté compositions that have a predetermined characeteristic, such as a lowered amount of caffeine, elevated amounts of caffeoyls, and/or lowered amounts of tannin compounds compared to the native maté plant materials. Further, the invention comprises methods of additional processing steps tp produce compositions having a predetermined alkaloid ratio or profiles to meet particular considerations for final products. The compositions of the present invention may be processed for specific uses such as tablets or other oral delivery vehicles. These compositions may be used in methods for treatment of physiological and medical conditions.
摘要翻译：本发明包括用于制备衍生自具有降低的咖啡因和单宁浓度的Ilex种，特别是白僵菌的组合物的组合物的方法，通过这些方法制备的组合物，口服递送制剂和使用该组合物的方法。特别地，本发明包括与天然植物材料相比制备具有预定特征的，例如降低量的咖啡因，提高量的咖啡因和/或降低量的单宁化合物的方法。此外，本发明包括附加处理步骤的方法，tp产生具有预定生物碱比例或分布的组合物以满足最终产品的特定考虑。本发明的组合物可以用于特定用途，例如片剂或其它口服递送载体。这些组合物可用于治疗生理和医学状况的方法。

2. 发明申请

WO2005041997A8 METHODS AND COMPOSITIONS COMPRISING ILEX 审中-公开
标题翻译：包含ILEX的方法和组合物
公开(公告)号：WO2005041997A8
公开(公告)日：2006-08-10
申请号：PCT/US2004035098
申请日：2004-10-25
申请人： HERBALSCIENCE LLC , GOW ROBERT T , SYPERT GEORGE W , PIERCE JOHN W , MARENTIS RODGE M , LI DAN , YAN XUN
发明人： GOW ROBERT T , SYPERT GEORGE W , PIERCE JOHN W , MARENTIS RODGE M , LI DAN , YAN XUN
IPC分类号： A23F3/00 , A61K31/522 , A61K36/00 , A61K36/185
CPC分类号： A61K36/185
摘要： The present invention comprises methods for making compositions derived from Ilex species, particularly Ilex paraguariensis, having lowered caffeine and tannin concentrations, compositions made by such methods, oral delivery formulations, and methods of use of such compositions. In particular, the present invention comprises methods for making maté compositions that have a predetermined characeteristic, such as a lowered amount of caffeine, elevated amounts of caffeoyls, and/or lowered amounts of tannin compounds compared to the native maté plant materials. Further, the invention comprises methods of additional processing steps tp produce compositions having a predetermined alkaloid ratio or profiles to meet particular considerations for final products. The compositions of the present invention may be processed for specific uses such as tablets or other oral delivery vehicles. These compositions may be used in methods for treatment of physiological and medical conditions.
摘要翻译：本发明包括用于制备衍生自具有降低的咖啡因和单宁浓度的Ilex种，特别是白僵菌的组合物的组合物的方法，通过这些方法制备的组合物，口服递送制剂和使用该组合物的方法。特别地，本发明包括与天然植物材料相比制备具有预定特征的maté组合物的方法，例如降低量的咖啡因，升高的咖啡因量和/或降低量的单宁化合物。此外，本发明包括另外的加工步骤的方法，tp产生具有预定生物碱比例或轮廓的组合物以满足最终产品的特定考虑。本发明的组合物可以用于特定用途如片剂或其它口服递送载体。这些组合物可用于治疗生理和医学状况的方法。

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