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1. 发明申请

WO2005041997A1 METHODS AND COMPOSITIONS COMPRISING ILEX 审中-公开
标题翻译：包含ILEX的方法和组合
公开(公告)号：WO2005041997A1
公开(公告)日：2005-05-12
申请号：PCT/US2004/035098
申请日：2004-10-25
申请人： HERBALSCIENCE LLC? , GOW, Robert, T. , SYPERT, George, W. , PIERCE, John, W. , MARENTIS, Rodge, M. , LI, Dan? , YAN, Xun?
发明人： GOW, Robert, T. , SYPERT, George, W. , PIERCE, John, W. , MARENTIS, Rodge, M. , LI, Dan? , YAN, Xun?
IPC分类号： A61K35/78
CPC分类号： A61K36/185
摘要： The present invention comprises methods for making compositions derived from Ilex species, particularly Ilex paraguariensis , having lowered caffeine and tannin concentrations, compositions made by such methods, oral delivery formulations, and methods of use of such compositions. In particular, the present invention comprises methods for making maté compositions that have a predetermined characeteristic, such as a lowered amount of caffeine, elevated amounts of caffeoyls, and/or lowered amounts of tannin compounds compared to the native maté plant materials. Further, the invention comprises methods of additional processing steps tp produce compositions having a predetermined alkaloid ratio or profiles to meet particular considerations for final products. The compositions of the present invention may be processed for specific uses such as tablets or other oral delivery vehicles. These compositions may be used in methods for treatment of physiological and medical conditions.
摘要翻译：本发明包括用于制备衍生自具有降低的咖啡因和单宁浓度的Ilex种，特别是白僵菌的组合物的组合物的方法，通过这些方法制备的组合物，口服递送制剂和使用该组合物的方法。特别地，本发明包括与天然植物材料相比制备具有预定特征的，例如降低量的咖啡因，提高量的咖啡因和/或降低量的单宁化合物的方法。此外，本发明包括附加处理步骤的方法，tp产生具有预定生物碱比例或分布的组合物以满足最终产品的特定考虑。本发明的组合物可以用于特定用途，例如片剂或其它口服递送载体。这些组合物可用于治疗生理和医学状况的方法。

2. 发明申请

WO2005039612A1 METHODS AND COMPOSITIONS COMPRISING ILEX 审中-公开
标题翻译：包含ILEX的方法和组合物
公开(公告)号：WO2005039612A1
公开(公告)日：2005-05-06
申请号：PCT/US2004/035170
申请日：2004-10-22
申请人： HERBALSCIENCE LLC , GOW, Robert, T. , SYPERT, George, W. , PIERCE, John, W. , MARENTIS, Rodger, M. , LI, Dan , YAN, Xun
发明人： GOW, Robert, T. , SYPERT, George, W. , PIERCE, John, W. , MARENTIS, Rodger, M. , LI, Dan , YAN, Xun
IPC分类号： A61K35/78
CPC分类号： A61K36/185
摘要： The present invention comprises methods for making compositions derived from Ilex species, particularly Ilex paraguariensis, having lowered caffeine and tannin concentrations, compositions made by such methods, oral delivery formulations, and methods of use of such compositions. In particular, the present invention comprises methods for making maté compositions that have a predetermined characeteristic, such as a lowered amount of caffeine, elevated amounts of caffeoyls, and/or lowered amounts of tannin compounds compared to the native maté plant materials. Further, the invention comprises methods of additional processing steps tp produce compositions having a predetermined alkaloid ratio or profiles to meet particular considerations for final products. The compositions of the present invention may be processed for specific uses such as tablets or other oral delivery vehicles. These compositions may be used in methods for treatment of physiological and medical conditions.
摘要翻译：本发明包括用于制备衍生自冬青属物种，特别是巴拉圭冬青属的具有降低的咖啡因和单宁浓度的组合物的方法，通过这种方法制备的组合物，口服递送制剂以及使用这些组合物的方法。特别地，本发明包括制作垫子的方法; 具有预定特征的组合物，例如咖啡因含量降低，咖啡酰含量增加，和/或单宁化合物含量与天然成分相比降低; 植物材料。此外，本发明包括另外的加工步骤的方法以产生具有预定生物碱比例或分布的组合物以满足最终产品的特定考虑。本发明的组合物可以加工用于特定用途，例如片剂或其他口服递送载体。这些组合物可以用于治疗生理和医学病症的方法中。

3. 发明申请

WO2007035723A3 COMPOSITIONS AND METHODS COMPRISING PANAX SPECIES 审中-公开
公开(公告)号：WO2007035723A3
公开(公告)日：2007-03-29
申请号：PCT/US2006/036464
申请日：2006-09-19
申请人： HERBALSCIENCE SINGAPORE PTE. LTD. , GOW, Robert, T. , SYPERT, George, W. , YAN, Xun , LI, Dan
发明人： GOW, Robert, T. , SYPERT, George, W. , YAN, Xun , LI, Dan
IPC分类号： A01N65/00 , A61K36/254 , A61K36/258
摘要： Compositions comprising elevated amounts of a ginsenosides, polyacetylenes, essential oil and/or polysaccharide are described, as are preferred extraction methods.

4. 发明申请

WO2007109600A3 EXTRACTIONS AND METHODS COMPRISING ELDER SPECIES 审中-公开
公开(公告)号：WO2007109600A3
公开(公告)日：2007-09-27
申请号：PCT/US2007/064286
申请日：2007-03-19
申请人： HERBALSCIENCE SINGAPORE PTE. LTD. , GOW, Robert, T. , SYPERT, George, W. , LI, Dan , ALBERTE, Randall, S.
发明人： GOW, Robert, T. , SYPERT, George, W. , LI, Dan , ALBERTE, Randall, S.
IPC分类号： A01N65/00 , A61K36/00
摘要： The present invention relates to extracts of elder species plant material prepared by supercritical CO 2 extractions methods, methods of treating viruses in a subject and methods of inhibiting viral infections in cells thereof.

5. 发明申请

WO2008036932A2 COMPOSITIONS AND METHODS COMPRISING BOSWELLIA SPECIES 审中-公开
标题翻译：包含鲍氏属植物的组合物和方法
公开(公告)号：WO2008036932A2
公开(公告)日：2008-03-27
申请号：PCT/US2007/079211
申请日：2007-09-21
申请人： HERBAL SCIENCE SINGAPORE PTE. LTD. , LI, Dan , GOW, Robert, T. , SYPERT, George, W.
发明人： LI, Dan , GOW, Robert, T. , SYPERT, George, W.
IPC分类号： A61K36/324
CPC分类号： A61K36/324 , A61K31/19
摘要： In certain aspects the invention features novel compositions and pharmaceutical preparations of the same. In certain embodiments, the compositions comprise α- and/or β- boswellic acid and/or their C-acetates in an amount greater than 65% by weight.
摘要翻译：在某些方面，本发明的特征在于其新颖的组合物和药物制剂。在某些实施方案中，组合物包含大于65重量％的α-和/或β-乳香酸和/或其C-乙酸酯。

6. 发明申请

WO2007109801A2 EXTRACTS AND METHODS COMPRISING GANODERMA SPECIES 审中-公开
标题翻译：提取物和方法包括GANODERMA物种
公开(公告)号：WO2007109801A2
公开(公告)日：2007-09-27
申请号：PCT/US2007/064829
申请日：2007-03-23
申请人： HERBALSCIENCE SINGAPORE PTE. LTD. , GOW, Robert, T. , LI, Dan , SYPERT, George, W. , ALBERTE, Randall, S.
发明人： GOW, Robert, T. , LI, Dan , SYPERT, George, W. , ALBERTE, Randall, S.
IPC分类号： A61K36/074
CPC分类号： A61K36/074
摘要： The present invention relates to extracts of ganoderma species plant material prepared by supercritical CO 2 extractions.
摘要翻译：本发明涉及通过超临界CO 2萃取制备的灵芝种植物材料的提取物。

7. 发明申请

WO2008070783A2 COMPOSITIONS AND METHODS COMPRISING ZINGIBER SPECIES 审中-公开
标题翻译：包含ZINGIBER物种的组合物和方法
公开(公告)号：WO2008070783A2
公开(公告)日：2008-06-12
申请号：PCT/US2007/086653
申请日：2007-12-06
申请人： HERBALSCIENCE SINGAPORE PTE. LTD. , LI, Dan , SYPERT, George, W. , GOW, Robert, T.
发明人： LI, Dan , SYPERT, George, W. , GOW, Robert, T.
IPC分类号： A61K36/906 , A61K31/715 , A61K31/12 , A61P43/00
CPC分类号： A61K36/9068 , A61K31/12 , A61K31/715
摘要： An aspect of the present invention relates to compositions comprising a gingerol, for example, compositions comprising gingerol in an amount greater than about 2% by weight. In some aspects of the invention, the composition comprises 6-gingerol, 8-gingerol, 10- gingerol, 6-shagaol, or combinations thereof. Another aspect of the invention relates to a method for extracting a ginger species comprising, sequentially extracting a ginger species plant material to yield an essential oil fraction, a gingerol fraction, a phenolic fraction, and a polysaccharide fraction, wherein the essential oil and gingerol fractions are derived by extracting plant feedstock material by supercritical carbon dioxide extraction, the phenolic fraction is extracted from the plant feedstock material or from the remainder of the essential oil and gingerol extractions by hydroalcoholic extraction, and the polysaccharide fraction is derived by water extraction of the remainder of the phenolic extraction.
摘要翻译：本发明的一个方面涉及包含姜醇的组合物，例如包含量大于约2重量％的姜酚的组合物。在本发明的一些方面，组合物包含6-姜醇，8-姜醇，10-姜油，6-莽草醇或其组合。本发明的另一方面涉及一种用于提取生姜物种的方法，包括：依次提取姜种植物材料以产生精油馏分，姜油醇馏分，酚馏分和多糖级分，其中所述精油和姜醇馏分通过超临界二氧化碳提取提取植物原料，通过水醇提取从植物原料或其余的精油和姜油中提取酚类成分，多糖级分是通过水提取其余部分得到的的酚提取。

8. 发明申请

WO2007109210A2 EXTRACTS AND METHODS COMPRISING CURCUMA SPECIES 审中-公开
标题翻译：提取和包含MA MA种的方法
公开(公告)号：WO2007109210A2
公开(公告)日：2007-09-27
申请号：PCT/US2007/006771
申请日：2007-03-16
申请人： HERBALSCIENCE SINGAPORE PTE. LTD. , LI, Dan , GOW, Robert, T. , SYPERT, George, W. , MANVILLE, H., Brock , ALBERTE, Randall, S.
发明人： LI, Dan , GOW, Robert, T. , SYPERT, George, W. , MANVILLE, H., Brock , ALBERTE, Randall, S.
IPC分类号： A61K36/9066
CPC分类号： A61K36/9066 , A23L33/105 , A23V2002/00 , A23V2250/21 , A23V2200/30 , A23V2250/2112
摘要： The present invention relates to extracts of curcuma species plant material using supercritical CO2 extraction methods, methods of treating a subject suffering from suffering from amyloid plaque aggregation or fibril formation associated with, for example, Alzheimer's disease, and methods of inhibiting amyloid plaque aggregation or fibril formation in tissue thereof.
摘要翻译：本发明涉及使用超临界CO 2提取方法的姜黄种植物材料的提取物，治疗患有与例如阿尔茨海默氏病相关的淀粉样蛋白斑块聚集或原纤维形成的受试者的方法，以及抑制淀粉样蛋白斑块聚集或原纤维的方法在其组织中形成。

9. 发明申请

WO2007109804A2 EXTRACTS AND METHODS COMPRISING CINNAMON SPECIES 审中-公开
标题翻译：提取物和包含中华物种的方法
公开(公告)号：WO2007109804A2
公开(公告)日：2007-09-27
申请号：PCT/US2007/064832
申请日：2007-03-23
申请人： HERBALSCIENCE SINGAPORE PTE. LTD. , GOW, Robert, T. , SYPERT, George, W. , LI, Dan , ALBERTE, Randall, S.
发明人： GOW, Robert, T. , SYPERT, George, W. , LI, Dan , ALBERTE, Randall, S.
IPC分类号： A23L1/28 , A61K36/54 , A61P39/06 , C07C29/00 , C07C39/12 , C07C39/18 , C07C47/54 , C07C63/04 , C07D311/04 , C07H17/02
CPC分类号： C07C47/232 , A23L27/12 , A23L33/105 , A23V2002/00 , A61K36/54 , C07C29/76 , C07C31/125 , C07C33/02 , C07C33/14 , C07C33/32 , C07C35/30 , C07C45/78 , C07C47/27 , C07C47/277 , C07C47/54 , C07C51/47 , C07C67/56 , C07D311/40 , C07H17/02 , Y02P20/544 , C07C57/44 , C07C69/618 , C07C69/007 , A23V2200/15 , A23V2250/708 , A23V2250/264 , C07C69/157
摘要： The present invention relates to extracts of cinnamon species plant material prepared by supercritical CO 2 extractions methods.
摘要翻译：本发明涉及通过超临界CO 2萃取方法制备的肉桂种植物材料的提取物。

10. 发明申请

WO2007109802A2 EXTRACTS AND METHODS COMPRISING GREEN TEA SPECIES 审中-公开
标题翻译：包含绿茶种的提取物和方法
公开(公告)号：WO2007109802A2
公开(公告)日：2007-09-27
申请号：PCT/US2007/064830
申请日：2007-03-23
申请人： HERBALSCIENCE SINGAPORE PTE. LTD. , GOW, Robert, T. , SYPERT, George, W. , LI, Dan , ALBERTE, Randall, S.
发明人： GOW, Robert, T. , SYPERT, George, W. , LI, Dan , ALBERTE, Randall, S.
IPC分类号： A61K36/82
CPC分类号： A61K36/82
摘要： The present invention relates to extracts of green tea species plant material prepared by supercritical CO 2 extractions methods.
摘要翻译：本发明涉及通过超临界CO 2萃取方法制备的绿茶种植物材料的提取物。

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